Btz domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QI83_LEIMA

TriTrypDb:

LmjF.08.0860 , LMJSD75_080012600

Length:

290

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QI83

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QI83

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	150	154	PF00656	0.692
CLV_C14_Caspase3-7	157	161	PF00656	0.580
CLV_C14_Caspase3-7	177	181	PF00656	0.677
CLV_NRD_NRD_1	140	142	PF00675	0.703
CLV_NRD_NRD_1	167	169	PF00675	0.650
CLV_NRD_NRD_1	214	216	PF00675	0.732
CLV_NRD_NRD_1	220	222	PF00675	0.699
CLV_NRD_NRD_1	29	31	PF00675	0.689
CLV_NRD_NRD_1	6	8	PF00675	0.702
CLV_PCSK_KEX2_1	139	141	PF00082	0.693
CLV_PCSK_KEX2_1	167	169	PF00082	0.650
CLV_PCSK_KEX2_1	214	216	PF00082	0.732
CLV_PCSK_KEX2_1	220	222	PF00082	0.699
CLV_PCSK_KEX2_1	29	31	PF00082	0.689
CLV_PCSK_KEX2_1	5	7	PF00082	0.701
CLV_PCSK_PC1ET2_1	139	141	PF00082	0.699
CLV_PCSK_SKI1_1	220	224	PF00082	0.616
DOC_MAPK_gen_1	101	109	PF00069	0.681
DOC_PP4_MxPP_1	199	202	PF00568	0.733
DOC_USP7_MATH_1	20	24	PF00917	0.716
DOC_USP7_MATH_1	210	214	PF00917	0.698
DOC_USP7_MATH_1	225	229	PF00917	0.592
DOC_USP7_UBL2_3	133	137	PF12436	0.690
DOC_WW_Pin1_4	22	27	PF00397	0.662
DOC_WW_Pin1_4	221	226	PF00397	0.628
DOC_WW_Pin1_4	233	238	PF00397	0.701
DOC_WW_Pin1_4	243	248	PF00397	0.583
DOC_WW_Pin1_4	257	262	PF00397	0.601
LIG_14-3-3_CanoR_1	140	148	PF00244	0.682
LIG_14-3-3_CanoR_1	7	16	PF00244	0.612
LIG_14-3-3_CanoR_1	95	100	PF00244	0.544
LIG_AP2alpha_1	205	209	PF02296	0.764
LIG_AP2alpha_2	187	189	PF02296	0.725
LIG_AP2alpha_2	284	286	PF02296	0.501
LIG_BIR_III_2	207	211	PF00653	0.653
LIG_BRCT_BRCA1_1	244	248	PF00533	0.512
LIG_BRCT_BRCA1_1	80	84	PF00533	0.521
LIG_deltaCOP1_diTrp_1	183	189	PF00928	0.669
LIG_EVH1_2	201	205	PF00568	0.744
LIG_FHA_1	247	253	PF00498	0.492
LIG_FHA_1	37	43	PF00498	0.573
LIG_FHA_2	29	35	PF00498	0.506
LIG_LIR_Apic_2	183	188	PF02991	0.726
LIG_LIR_Nem_3	284	289	PF02991	0.522
LIG_LIR_Nem_3	50	56	PF02991	0.520
LIG_LIR_Nem_3	81	87	PF02991	0.498
LIG_Pex14_2	205	209	PF04695	0.764
LIG_Pex14_2	65	69	PF04695	0.633
LIG_SH2_GRB2like	56	59	PF00017	0.483
LIG_SH2_NCK_1	158	162	PF00017	0.700
LIG_SH2_STAP1	53	57	PF00017	0.506
LIG_SH2_STAT5	86	89	PF00017	0.583
LIG_SH3_2	258	263	PF14604	0.600
LIG_SH3_3	106	112	PF00018	0.728
LIG_SH3_3	146	152	PF00018	0.643
LIG_SH3_3	255	261	PF00018	0.567
LIG_SUMO_SIM_par_1	105	111	PF11976	0.759
LIG_TRAF2_1	64	67	PF00917	0.515
MOD_CDC14_SPxK_1	260	263	PF00782	0.592
MOD_CDK_SPxK_1	257	263	PF00069	0.598
MOD_CDK_SPxxK_3	22	29	PF00069	0.647
MOD_CDK_SPxxK_3	233	240	PF00069	0.699
MOD_CK1_1	121	127	PF00069	0.691
MOD_CK1_1	228	234	PF00069	0.774
MOD_CK1_1	236	242	PF00069	0.636
MOD_CK1_1	246	252	PF00069	0.427
MOD_CK2_1	22	28	PF00069	0.593
MOD_Cter_Amidation	169	172	PF01082	0.772
MOD_GlcNHglycan	123	126	PF01048	0.722
MOD_GlcNHglycan	22	25	PF01048	0.605
MOD_GlcNHglycan	80	83	PF01048	0.639
MOD_GSK3_1	221	228	PF00069	0.750
MOD_GSK3_1	242	249	PF00069	0.523
MOD_GSK3_1	34	41	PF00069	0.544
MOD_GSK3_1	52	59	PF00069	0.585
MOD_GSK3_1	78	85	PF00069	0.514
MOD_N-GLC_1	228	233	PF02516	0.565
MOD_N-GLC_1	95	100	PF02516	0.579
MOD_NEK2_1	252	257	PF00069	0.652
MOD_NEK2_1	52	57	PF00069	0.592
MOD_NEK2_1	78	83	PF00069	0.514
MOD_PK_1	223	229	PF00069	0.564
MOD_PKA_1	139	145	PF00069	0.684
MOD_PKA_1	6	12	PF00069	0.693
MOD_PKA_2	139	145	PF00069	0.699
MOD_PKA_2	28	34	PF00069	0.471
MOD_PKA_2	6	12	PF00069	0.637
MOD_PKA_2	70	76	PF00069	0.498
MOD_PKB_1	45	53	PF00069	0.455
MOD_Plk_1	95	101	PF00069	0.578
MOD_Plk_2-3	151	157	PF00069	0.551
MOD_Plk_4	190	196	PF00069	0.702
MOD_Plk_4	38	44	PF00069	0.496
MOD_Plk_4	52	58	PF00069	0.538
MOD_Plk_4	95	101	PF00069	0.543
MOD_ProDKin_1	22	28	PF00069	0.653
MOD_ProDKin_1	221	227	PF00069	0.628
MOD_ProDKin_1	233	239	PF00069	0.697
MOD_ProDKin_1	243	249	PF00069	0.583
MOD_ProDKin_1	257	263	PF00069	0.604
TRG_ER_diArg_1	103	106	PF00400	0.719
TRG_ER_diArg_1	166	168	PF00400	0.583
TRG_ER_diArg_1	220	222	PF00400	0.643
TRG_ER_diArg_1	29	32	PF00400	0.692
TRG_ER_diArg_1	5	7	PF00400	0.701

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEG2	Leptomonas seymouri	39%	100%
A0A3S5H670	Leishmania donovani	87%	100%
A4H6C7	Leishmania braziliensis	58%	91%
A4HTM6	Leishmania infantum	87%	100%
E9AMG0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%