DnaJ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein, putative

Species:

Leishmania major

UniProt:

Q4QI70_LEIMA

TriTrypDb:

LmjF.08.0990 , LMJLV39_080014500 , LMJSD75_080014600

Length:

326

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QI70

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QI70

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	251	255	PF00656	0.638
CLV_NRD_NRD_1	155	157	PF00675	0.400
CLV_NRD_NRD_1	18	20	PF00675	0.460
CLV_NRD_NRD_1	183	185	PF00675	0.299
CLV_NRD_NRD_1	232	234	PF00675	0.577
CLV_NRD_NRD_1	273	275	PF00675	0.537
CLV_NRD_NRD_1	295	297	PF00675	0.502
CLV_NRD_NRD_1	316	318	PF00675	0.432
CLV_NRD_NRD_1	43	45	PF00675	0.421
CLV_NRD_NRD_1	87	89	PF00675	0.472
CLV_PCSK_KEX2_1	119	121	PF00082	0.596
CLV_PCSK_KEX2_1	155	157	PF00082	0.400
CLV_PCSK_KEX2_1	183	185	PF00082	0.299
CLV_PCSK_KEX2_1	272	274	PF00082	0.680
CLV_PCSK_KEX2_1	294	296	PF00082	0.467
CLV_PCSK_KEX2_1	84	86	PF00082	0.445
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.596
CLV_PCSK_PC1ET2_1	272	274	PF00082	0.680
CLV_PCSK_PC1ET2_1	84	86	PF00082	0.445
CLV_PCSK_PC7_1	269	275	PF00082	0.549
CLV_PCSK_SKI1_1	155	159	PF00082	0.411
CLV_PCSK_SKI1_1	226	230	PF00082	0.571
CLV_PCSK_SKI1_1	296	300	PF00082	0.589
CLV_PCSK_SKI1_1	45	49	PF00082	0.406
DOC_MAPK_gen_1	220	229	PF00069	0.486
DOC_MAPK_gen_1	315	325	PF00069	0.446
DOC_MAPK_gen_1	41	50	PF00069	0.445
DOC_MAPK_MEF2A_6	41	50	PF00069	0.436
DOC_PP1_RVXF_1	219	226	PF00149	0.429
DOC_SPAK_OSR1_1	224	228	PF12202	0.428
DOC_USP7_MATH_1	103	107	PF00917	0.592
DOC_USP7_MATH_1	132	136	PF00917	0.463
DOC_USP7_MATH_1	260	264	PF00917	0.569
DOC_WW_Pin1_4	19	24	PF00397	0.443
LIG_APCC_ABBA_1	48	53	PF00400	0.418
LIG_CAP-Gly_1	319	326	PF01302	0.466
LIG_deltaCOP1_diTrp_1	319	326	PF00928	0.466
LIG_eIF4E_1	43	49	PF01652	0.406
LIG_EVH1_2	129	133	PF00568	0.516
LIG_FHA_1	135	141	PF00498	0.448
LIG_FHA_1	31	37	PF00498	0.439
LIG_FHA_2	175	181	PF00498	0.299
LIG_FHA_2	205	211	PF00498	0.324
LIG_FHA_2	263	269	PF00498	0.513
LIG_LIR_Gen_1	163	173	PF02991	0.299
LIG_LIR_Gen_1	204	212	PF02991	0.309
LIG_LIR_Gen_1	22	32	PF02991	0.423
LIG_LIR_Gen_1	319	326	PF02991	0.460
LIG_LIR_Nem_3	163	169	PF02991	0.299
LIG_LIR_Nem_3	204	209	PF02991	0.309
LIG_LIR_Nem_3	22	27	PF02991	0.404
LIG_LIR_Nem_3	319	323	PF02991	0.436
LIG_LIR_Nem_3	77	83	PF02991	0.429
LIG_Pex14_2	225	229	PF04695	0.477
LIG_SH2_CRK	43	47	PF00017	0.398
LIG_SH2_STAT3	87	90	PF00017	0.513
LIG_SH2_STAT5	165	168	PF00017	0.314
LIG_SH2_STAT5	26	29	PF00017	0.354
LIG_SUMO_SIM_par_1	167	172	PF11976	0.299
LIG_TRAF2_1	265	268	PF00917	0.531
LIG_TYR_ITSM	161	168	PF00017	0.299
LIG_UBA3_1	79	84	PF00899	0.429
MOD_CK1_1	142	148	PF00069	0.477
MOD_CK1_1	174	180	PF00069	0.382
MOD_CK1_1	75	81	PF00069	0.551
MOD_CK2_1	19	25	PF00069	0.438
MOD_CK2_1	204	210	PF00069	0.348
MOD_CK2_1	262	268	PF00069	0.562
MOD_GlcNHglycan	141	144	PF01048	0.546
MOD_GlcNHglycan	248	251	PF01048	0.579
MOD_GlcNHglycan	99	102	PF01048	0.610
MOD_GSK3_1	139	146	PF00069	0.542
MOD_GSK3_1	204	211	PF00069	0.348
MOD_GSK3_1	30	37	PF00069	0.458
MOD_GSK3_1	97	104	PF00069	0.694
MOD_NEK2_1	139	144	PF00069	0.492
MOD_PIKK_1	134	140	PF00454	0.478
MOD_PIKK_1	72	78	PF00454	0.427
MOD_Plk_1	260	266	PF00069	0.601
MOD_Plk_1	304	310	PF00069	0.488
MOD_Plk_2-3	204	210	PF00069	0.477
MOD_Plk_4	75	81	PF00069	0.480
MOD_ProDKin_1	19	25	PF00069	0.447
MOD_SUMO_for_1	298	301	PF00179	0.519
MOD_SUMO_rev_2	215	223	PF00179	0.345
TRG_DiLeu_BaEn_1	9	14	PF01217	0.400
TRG_DiLeu_LyEn_5	9	14	PF01217	0.360
TRG_ENDOCYTIC_2	165	168	PF00928	0.299
TRG_ENDOCYTIC_2	185	188	PF00928	0.299
TRG_ENDOCYTIC_2	26	29	PF00928	0.354
TRG_ENDOCYTIC_2	43	46	PF00928	0.403
TRG_ER_diArg_1	154	156	PF00400	0.407
TRG_ER_diArg_1	183	185	PF00400	0.344
TRG_ER_diArg_1	273	275	PF00400	0.597
TRG_ER_diArg_1	294	296	PF00400	0.499
TRG_NES_CRM1_1	198	210	PF08389	0.299
TRG_Pf-PMV_PEXEL_1	12	17	PF00026	0.354
TRG_Pf-PMV_PEXEL_1	296	300	PF00026	0.547

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIH8	Leptomonas seymouri	75%	98%
A0A3S7WQC4	Leishmania donovani	96%	100%
A4HTN9	Leishmania infantum	97%	100%
E9AMH3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%