RNA-binding protein 5-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein 5-like protein

Species:

Leishmania major

UniProt:

Q4QI27_LEIMA

TriTrypDb:

LmjF.09.0080 , LMJLV39_090006000 , LMJSD75_090006000

Length:

245

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2
GO:1990904	ribonucleoprotein complex	2	2

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Expansion

Sequence features

Q4QI27

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QI27

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	132	136	PF00656	0.534
CLV_NRD_NRD_1	94	96	PF00675	0.595
CLV_PCSK_KEX2_1	94	96	PF00082	0.595
CLV_PCSK_PC7_1	90	96	PF00082	0.366
DEG_SIAH_1	162	170	PF03145	0.601
DOC_CKS1_1	108	113	PF01111	0.607
DOC_CYCLIN_yCln2_LP_2	108	114	PF00134	0.610
DOC_USP7_MATH_1	150	154	PF00917	0.529
DOC_USP7_MATH_1	157	161	PF00917	0.719
DOC_USP7_MATH_1	171	175	PF00917	0.498

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P379	Leptomonas seymouri	47%	100%
A0A3S5H6A8	Leishmania donovani	93%	100%
A4H5I5	Leishmania braziliensis	81%	100%
A4HTS6	Leishmania infantum	93%	100%
E9AMK9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
P0CB38	Homo sapiens	23%	66%

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