RNA-binding protein 5-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein 5-like protein

Species:

Leishmania major

UniProt:

Q4QI26_LEIMA

TriTrypDb:

LmjF.09.0090 , LMJLV39_090006100 , LMJSD75_090006100

Length:

298

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0032991	protein-containing complex	1	2
GO:1990904	ribonucleoprotein complex	2	2

Expansion

Sequence features

Q4QI26

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QI26

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	122	128	PF00089	0.346
CLV_NRD_NRD_1	177	179	PF00675	0.529
CLV_PCSK_KEX2_1	124	126	PF00082	0.346
CLV_PCSK_KEX2_1	177	179	PF00082	0.529
CLV_PCSK_PC1ET2_1	124	126	PF00082	0.346
DOC_CKS1_1	32	37	PF01111	0.772
DOC_CYCLIN_yCln2_LP_2	32	38	PF00134	0.772
DOC_PP2B_LxvP_1	51	54	PF13499	0.637
DOC_USP7_MATH_1	100	104	PF00917	0.485
DOC_USP7_MATH_1	128	132	PF00917	0.619
DOC_USP7_MATH_1	81	85	PF00917	0.755
DOC_WW_Pin1_4	210	215	PF00397	0.660
DOC_WW_Pin1_4	237	242	PF00397	0.757
DOC_WW_Pin1_4	24	29	PF00397	0.627
DOC_WW_Pin1_4	31	36	PF00397	0.667
DOC_WW_Pin1_4	77	82	PF00397	0.661
LIG_14-3-3_CanoR_1	177	187	PF00244	0.600
LIG_14-3-3_CanoR_1	206	215	PF00244	0.769
LIG_BRCT_BRCA1_1	194	198	PF00533	0.782
LIG_BRCT_MDC1_1	294	298	PF00533	0.685
LIG_deltaCOP1_diTrp_1	14	17	PF00928	0.757
LIG_FHA_1	234	240	PF00498	0.766
LIG_FHA_1	292	298	PF00498	0.756
LIG_FHA_2	113	119	PF00498	0.514
LIG_FHA_2	195	201	PF00498	0.683
LIG_FHA_2	20	26	PF00498	0.672
LIG_FHA_2	40	46	PF00498	0.631
LIG_Integrin_isoDGR_2	268	270	PF01839	0.682
LIG_LIR_Gen_1	14	24	PF02991	0.760
LIG_LIR_Gen_1	2	13	PF02991	0.632
LIG_LIR_Gen_1	278	288	PF02991	0.749
LIG_LIR_Nem_3	121	126	PF02991	0.543
LIG_LIR_Nem_3	14	20	PF02991	0.762
LIG_LIR_Nem_3	2	8	PF02991	0.633
LIG_LIR_Nem_3	228	232	PF02991	0.697
LIG_LIR_Nem_3	278	284	PF02991	0.753
LIG_PTAP_UEV_1	20	25	PF05743	0.760
LIG_PTAP_UEV_1	247	252	PF05743	0.676
LIG_PTB_Apo_2	227	234	PF02174	0.694
LIG_PTB_Phospho_1	227	233	PF10480	0.696
LIG_SH2_CRK	146	150	PF00017	0.546
LIG_SH2_CRK	281	285	PF00017	0.649
LIG_SH2_STAP1	101	105	PF00017	0.593
LIG_SH2_STAP1	217	221	PF00017	0.780
LIG_SH2_STAP1	75	79	PF00017	0.619
LIG_SH2_STAT5	106	109	PF00017	0.546
LIG_SH2_STAT5	243	246	PF00017	0.685
LIG_SH3_2	21	26	PF14604	0.760
LIG_SH3_3	18	24	PF00018	0.708
LIG_SH3_3	228	234	PF00018	0.751
LIG_SH3_3	245	251	PF00018	0.607
LIG_SH3_3	261	267	PF00018	0.711
LIG_SH3_5	71	75	PF00018	0.742
LIG_TYR_ITIM	279	284	PF00017	0.652
MOD_CDC14_SPxK_1	80	83	PF00782	0.658
MOD_CDK_SPxK_1	77	83	PF00069	0.662
MOD_CK1_1	181	187	PF00069	0.630
MOD_CK1_1	192	198	PF00069	0.701
MOD_CK1_1	201	207	PF00069	0.717
MOD_CK1_1	210	216	PF00069	0.655
MOD_CK1_1	62	68	PF00069	0.590
MOD_CK1_1	73	79	PF00069	0.600
MOD_CK2_1	106	112	PF00069	0.614
MOD_CK2_1	19	25	PF00069	0.607
MOD_CK2_1	194	200	PF00069	0.782
MOD_GlcNHglycan	130	133	PF01048	0.346
MOD_GlcNHglycan	180	183	PF01048	0.624
MOD_GlcNHglycan	191	194	PF01048	0.626
MOD_GlcNHglycan	200	204	PF01048	0.590
MOD_GlcNHglycan	248	251	PF01048	0.656
MOD_GlcNHglycan	286	289	PF01048	0.665
MOD_GlcNHglycan	294	297	PF01048	0.578
MOD_GlcNHglycan	48	51	PF01048	0.692
MOD_GlcNHglycan	59	62	PF01048	0.633
MOD_GSK3_1	181	188	PF00069	0.734
MOD_GSK3_1	192	199	PF00069	0.687
MOD_GSK3_1	201	208	PF00069	0.725
MOD_GSK3_1	221	228	PF00069	0.676
MOD_GSK3_1	233	240	PF00069	0.662
MOD_GSK3_1	62	69	PF00069	0.679
MOD_GSK3_1	73	80	PF00069	0.691
MOD_GSK3_1	83	90	PF00069	0.610
MOD_N-GLC_1	210	215	PF02516	0.724
MOD_N-GLC_1	253	258	PF02516	0.802
MOD_N-GLC_1	77	82	PF02516	0.661
MOD_N-GLC_1	87	92	PF02516	0.658
MOD_NEK2_1	198	203	PF00069	0.557
MOD_NEK2_1	284	289	PF00069	0.734
MOD_NEK2_1	291	296	PF00069	0.623
MOD_NEK2_1	36	41	PF00069	0.766
MOD_NEK2_1	46	51	PF00069	0.757
MOD_NEK2_1	59	64	PF00069	0.629
MOD_NEK2_1	87	92	PF00069	0.746
MOD_PIKK_1	221	227	PF00454	0.616
MOD_PIKK_1	255	261	PF00454	0.727
MOD_PKA_2	205	211	PF00069	0.711
MOD_Plk_1	215	221	PF00069	0.548
MOD_Plk_1	87	93	PF00069	0.712
MOD_Plk_2-3	112	118	PF00069	0.546
MOD_Plk_4	239	245	PF00069	0.725
MOD_ProDKin_1	210	216	PF00069	0.659
MOD_ProDKin_1	237	243	PF00069	0.760
MOD_ProDKin_1	24	30	PF00069	0.626
MOD_ProDKin_1	31	37	PF00069	0.666
MOD_ProDKin_1	77	83	PF00069	0.662
TRG_ENDOCYTIC_2	146	149	PF00928	0.543
TRG_ENDOCYTIC_2	281	284	PF00928	0.650
TRG_ER_diArg_1	176	178	PF00400	0.523

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2F1	Leptomonas seymouri	50%	96%
A0A3S7WQG5	Leishmania donovani	95%	100%
A4H5I6	Leishmania braziliensis	86%	100%
A4HTS7	Leishmania infantum	95%	100%
E9AML0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%