Axonemal_dynein_light_chain_-_putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QHV3_LEIMA

TriTrypDb:

LmjF.09.0710 , LMJLV39_090013300 , LMJSD75_090012900

Length:

516

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QHV3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QHV3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	306	310	PF00656	0.783
CLV_NRD_NRD_1	198	200	PF00675	0.621
CLV_NRD_NRD_1	301	303	PF00675	0.708
CLV_NRD_NRD_1	31	33	PF00675	0.678
CLV_NRD_NRD_1	312	314	PF00675	0.662
CLV_NRD_NRD_1	316	318	PF00675	0.644
CLV_NRD_NRD_1	416	418	PF00675	0.539
CLV_PCSK_KEX2_1	198	200	PF00082	0.621
CLV_PCSK_KEX2_1	301	303	PF00082	0.710
CLV_PCSK_KEX2_1	31	33	PF00082	0.678
CLV_PCSK_KEX2_1	312	314	PF00082	0.659
CLV_PCSK_KEX2_1	355	357	PF00082	0.836
CLV_PCSK_KEX2_1	416	418	PF00082	0.539
CLV_PCSK_KEX2_1	508	510	PF00082	0.648
CLV_PCSK_PC1ET2_1	355	357	PF00082	0.836
CLV_PCSK_PC1ET2_1	508	510	PF00082	0.648
CLV_PCSK_SKI1_1	100	104	PF00082	0.579
CLV_PCSK_SKI1_1	180	184	PF00082	0.583
CLV_PCSK_SKI1_1	189	193	PF00082	0.619
CLV_PCSK_SKI1_1	198	202	PF00082	0.648
CLV_PCSK_SKI1_1	206	210	PF00082	0.613
CLV_PCSK_SKI1_1	301	305	PF00082	0.573
CLV_PCSK_SKI1_1	31	35	PF00082	0.672
CLV_PCSK_SKI1_1	93	97	PF00082	0.600
DEG_Nend_UBRbox_1	1	4	PF02207	0.822
DEG_ODPH_VHL_1	253	266	PF01847	0.619
DEG_SCF_FBW7_1	374	380	PF00400	0.763
DEG_SPOP_SBC_1	21	25	PF00917	0.726
DOC_CKS1_1	374	379	PF01111	0.839
DOC_CKS1_1	53	58	PF01111	0.609
DOC_CYCLIN_RxL_1	298	306	PF00134	0.566
DOC_MAPK_gen_1	492	500	PF00069	0.514
DOC_MAPK_MEF2A_6	483	490	PF00069	0.564
DOC_MAPK_MEF2A_6	81	88	PF00069	0.557
DOC_MAPK_NFAT4_5	483	491	PF00069	0.570
DOC_PP1_RVXF_1	185	191	PF00149	0.606
DOC_PP1_RVXF_1	494	501	PF00149	0.627
DOC_PP1_SILK_1	259	264	PF00149	0.697
DOC_USP7_MATH_1	129	133	PF00917	0.751
DOC_USP7_MATH_1	137	141	PF00917	0.793
DOC_USP7_MATH_1	21	25	PF00917	0.556
DOC_USP7_MATH_1	257	261	PF00917	0.763
DOC_USP7_MATH_1	431	435	PF00917	0.645
DOC_USP7_MATH_1	9	13	PF00917	0.836
DOC_WW_Pin1_4	155	160	PF00397	0.784
DOC_WW_Pin1_4	165	170	PF00397	0.511
DOC_WW_Pin1_4	191	196	PF00397	0.607
DOC_WW_Pin1_4	253	258	PF00397	0.675
DOC_WW_Pin1_4	272	277	PF00397	0.499
DOC_WW_Pin1_4	373	378	PF00397	0.750
DOC_WW_Pin1_4	383	388	PF00397	0.777
DOC_WW_Pin1_4	411	416	PF00397	0.478
DOC_WW_Pin1_4	49	54	PF00397	0.758
DOC_WW_Pin1_4	67	72	PF00397	0.609
DOC_WW_Pin1_4	7	12	PF00397	0.731
LIG_14-3-3_CanoR_1	189	195	PF00244	0.609
LIG_14-3-3_CanoR_1	31	38	PF00244	0.670
LIG_14-3-3_CanoR_1	368	373	PF00244	0.616
LIG_14-3-3_CanoR_1	69	79	PF00244	0.695
LIG_14-3-3_CanoR_1	93	99	PF00244	0.589
LIG_APCC_ABBA_1	497	502	PF00400	0.703
LIG_APCC_ABBAyCdc20_2	496	502	PF00400	0.704
LIG_CtBP_PxDLS_1	387	391	PF00389	0.603
LIG_CtBP_PxDLS_1	438	442	PF00389	0.696
LIG_FHA_1	103	109	PF00498	0.485
LIG_FHA_1	146	152	PF00498	0.746
LIG_FHA_1	156	162	PF00498	0.684
LIG_FHA_1	166	172	PF00498	0.513
LIG_FHA_1	32	38	PF00498	0.668
LIG_FHA_1	81	87	PF00498	0.702
LIG_FHA_2	21	27	PF00498	0.707
LIG_FHA_2	346	352	PF00498	0.734
LIG_FHA_2	384	390	PF00498	0.842
LIG_FHA_2	451	457	PF00498	0.515
LIG_FHA_2	463	469	PF00498	0.599
LIG_LIR_Apic_2	124	129	PF02991	0.741
LIG_LIR_Gen_1	332	340	PF02991	0.694
LIG_LIR_Gen_1	452	463	PF02991	0.494
LIG_LIR_Nem_3	176	182	PF02991	0.574
LIG_LIR_Nem_3	332	337	PF02991	0.683
LIG_LIR_Nem_3	452	458	PF02991	0.486
LIG_PCNA_yPIPBox_3	172	180	PF02747	0.468
LIG_SH2_STAT5	419	422	PF00017	0.528
LIG_SH3_3	156	162	PF00018	0.725
LIG_SH3_3	242	248	PF00018	0.619
LIG_SH3_3	371	377	PF00018	0.739
LIG_SH3_3	48	54	PF00018	0.765
LIG_SH3_3	65	71	PF00018	0.618
LIG_SUMO_SIM_par_1	437	443	PF11976	0.692
LIG_SUMO_SIM_par_1	82	90	PF11976	0.484
LIG_TRAF2_1	386	389	PF00917	0.730
LIG_UBA3_1	261	265	PF00899	0.665
MOD_CDC14_SPxK_1	414	417	PF00782	0.530
MOD_CDK_SPK_2	253	258	PF00069	0.768
MOD_CDK_SPK_2	411	416	PF00069	0.538
MOD_CDK_SPxK_1	411	417	PF00069	0.534
MOD_CDK_SPxxK_3	191	198	PF00069	0.605
MOD_CDK_SPxxK_3	272	279	PF00069	0.585
MOD_CK1_1	12	18	PF00069	0.763
MOD_CK1_1	140	146	PF00069	0.819
MOD_CK1_1	22	28	PF00069	0.770
MOD_CK1_1	220	226	PF00069	0.800
MOD_CK1_1	230	236	PF00069	0.605
MOD_CK1_1	275	281	PF00069	0.753
MOD_CK1_1	332	338	PF00069	0.622
MOD_CK1_1	52	58	PF00069	0.608
MOD_CK1_1	70	76	PF00069	0.819
MOD_CK2_1	119	125	PF00069	0.814
MOD_CK2_1	20	26	PF00069	0.796
MOD_CK2_1	253	259	PF00069	0.740
MOD_CK2_1	345	351	PF00069	0.732
MOD_CK2_1	383	389	PF00069	0.796
MOD_CK2_1	437	443	PF00069	0.657
MOD_CK2_1	462	468	PF00069	0.555
MOD_CK2_1	70	76	PF00069	0.742
MOD_Cter_Amidation	196	199	PF01082	0.613
MOD_DYRK1A_RPxSP_1	155	159	PF00069	0.805
MOD_GlcNHglycan	100	103	PF01048	0.643
MOD_GlcNHglycan	11	14	PF01048	0.842
MOD_GlcNHglycan	121	124	PF01048	0.749
MOD_GlcNHglycan	222	225	PF01048	0.760
MOD_GlcNHglycan	284	287	PF01048	0.687
MOD_GlcNHglycan	331	334	PF01048	0.619
MOD_GlcNHglycan	361	364	PF01048	0.698
MOD_GlcNHglycan	38	41	PF01048	0.702
MOD_GlcNHglycan	470	473	PF01048	0.589
MOD_GSK3_1	117	124	PF00069	0.781
MOD_GSK3_1	253	260	PF00069	0.769
MOD_GSK3_1	270	277	PF00069	0.535
MOD_GSK3_1	278	285	PF00069	0.687
MOD_GSK3_1	3	10	PF00069	0.748
MOD_GSK3_1	373	380	PF00069	0.690
MOD_GSK3_1	462	469	PF00069	0.487
MOD_GSK3_1	94	101	PF00069	0.583
MOD_LATS_1	115	121	PF00433	0.716
MOD_N-GLC_1	19	24	PF02516	0.741
MOD_N-GLC_1	211	216	PF02516	0.570
MOD_N-GLC_1	383	388	PF02516	0.763
MOD_N-GLC_1	431	436	PF02516	0.603
MOD_NEK2_1	94	99	PF00069	0.581
MOD_PK_1	270	276	PF00069	0.579
MOD_PKA_1	31	37	PF00069	0.670
MOD_PKA_1	449	455	PF00069	0.629
MOD_PKA_2	218	224	PF00069	0.689
MOD_PKA_2	31	37	PF00069	0.670
MOD_PKA_2	367	373	PF00069	0.745
MOD_PKA_2	466	472	PF00069	0.469
MOD_PKB_1	155	163	PF00069	0.563
MOD_PKB_1	187	195	PF00069	0.712
MOD_Plk_1	137	143	PF00069	0.818
MOD_Plk_2-3	82	88	PF00069	0.484
MOD_Plk_4	137	143	PF00069	0.585
MOD_Plk_4	230	236	PF00069	0.712
MOD_Plk_4	257	263	PF00069	0.689
MOD_ProDKin_1	155	161	PF00069	0.776
MOD_ProDKin_1	165	171	PF00069	0.505
MOD_ProDKin_1	191	197	PF00069	0.603
MOD_ProDKin_1	253	259	PF00069	0.675
MOD_ProDKin_1	272	278	PF00069	0.502
MOD_ProDKin_1	373	379	PF00069	0.751
MOD_ProDKin_1	383	389	PF00069	0.775
MOD_ProDKin_1	411	417	PF00069	0.474
MOD_ProDKin_1	49	55	PF00069	0.758
MOD_ProDKin_1	67	73	PF00069	0.608
MOD_ProDKin_1	7	13	PF00069	0.732
MOD_SUMO_for_1	354	357	PF00179	0.832
TRG_DiLeu_BaEn_4	314	320	PF01217	0.760
TRG_DiLeu_BaLyEn_6	299	304	PF01217	0.568
TRG_DiLeu_LyEn_5	502	507	PF01217	0.702
TRG_ENDOCYTIC_2	455	458	PF00928	0.556
TRG_ER_diArg_1	154	157	PF00400	0.581
TRG_ER_diArg_1	187	190	PF00400	0.715
TRG_ER_diArg_1	301	303	PF00400	0.716
TRG_ER_diArg_1	31	33	PF00400	0.678
TRG_ER_diArg_1	311	313	PF00400	0.652
TRG_ER_diArg_1	415	417	PF00400	0.519
TRG_Pf-PMV_PEXEL_1	180	184	PF00026	0.571
TRG_Pf-PMV_PEXEL_1	301	306	PF00026	0.734
TRG_Pf-PMV_PEXEL_1	31	35	PF00026	0.672
TRG_Pf-PMV_PEXEL_1	317	322	PF00026	0.551
TRG_Pf-PMV_PEXEL_1	423	427	PF00026	0.668

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILK1	Leptomonas seymouri	37%	98%
A0A3S7WQP0	Leishmania donovani	91%	100%
A4H5Q2	Leishmania braziliensis	72%	97%
A4HTZ2	Leishmania infantum	91%	100%
E9AMS2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%