Kinetoplast-associated protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplast-associated protein-like protein

Species:

Leishmania major

UniProt:

Q4QHU4_LEIMA

TriTrypDb:

LmjF.09.0800 , LMJLV39_090014200 , LMJSD75_090013900

Length:

1286

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005858	axonemal dynein complex	4	2
GO:0005875	microtubule associated complex	2	2
GO:0030286	dynein complex	3	2
GO:0032991	protein-containing complex	1	2
GO:1902494	catalytic complex	2	2
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

Q4QHU4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1160	1164	PF00656	0.750
CLV_C14_Caspase3-7	1195	1199	PF00656	0.684
CLV_C14_Caspase3-7	23	27	PF00656	0.744
CLV_C14_Caspase3-7	450	454	PF00656	0.729
CLV_C14_Caspase3-7	535	539	PF00656	0.747
CLV_C14_Caspase3-7	723	727	PF00656	0.766
CLV_C14_Caspase3-7	73	77	PF00656	0.705
CLV_NRD_NRD_1	1048	1050	PF00675	0.463
CLV_NRD_NRD_1	1138	1140	PF00675	0.539
CLV_NRD_NRD_1	1230	1232	PF00675	0.589
CLV_NRD_NRD_1	1281	1283	PF00675	0.477
CLV_NRD_NRD_1	148	150	PF00675	0.494
CLV_NRD_NRD_1	163	165	PF00675	0.427
CLV_NRD_NRD_1	324	326	PF00675	0.321
CLV_NRD_NRD_1	356	358	PF00675	0.546
CLV_NRD_NRD_1	38	40	PF00675	0.589
CLV_NRD_NRD_1	401	403	PF00675	0.590
CLV_NRD_NRD_1	429	431	PF00675	0.522
CLV_NRD_NRD_1	851	853	PF00675	0.525
CLV_NRD_NRD_1	920	922	PF00675	0.419
CLV_NRD_NRD_1	968	970	PF00675	0.549
CLV_NRD_NRD_1	990	992	PF00675	0.439
CLV_PCSK_FUR_1	1228	1232	PF00082	0.534
CLV_PCSK_FUR_1	399	403	PF00082	0.593
CLV_PCSK_FUR_1	849	853	PF00082	0.523
CLV_PCSK_KEX2_1	1048	1050	PF00082	0.463
CLV_PCSK_KEX2_1	1138	1140	PF00082	0.539
CLV_PCSK_KEX2_1	1228	1230	PF00082	0.523
CLV_PCSK_KEX2_1	150	152	PF00082	0.509
CLV_PCSK_KEX2_1	163	165	PF00082	0.403
CLV_PCSK_KEX2_1	174	176	PF00082	0.309
CLV_PCSK_KEX2_1	184	186	PF00082	0.387
CLV_PCSK_KEX2_1	356	358	PF00082	0.546
CLV_PCSK_KEX2_1	38	40	PF00082	0.589
CLV_PCSK_KEX2_1	401	403	PF00082	0.590
CLV_PCSK_KEX2_1	428	430	PF00082	0.519
CLV_PCSK_KEX2_1	85	87	PF00082	0.545
CLV_PCSK_KEX2_1	851	853	PF00082	0.525
CLV_PCSK_KEX2_1	907	909	PF00082	0.582
CLV_PCSK_PC1ET2_1	150	152	PF00082	0.509
CLV_PCSK_PC1ET2_1	174	176	PF00082	0.338
CLV_PCSK_PC1ET2_1	184	186	PF00082	0.331
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.540
CLV_PCSK_PC1ET2_1	907	909	PF00082	0.471
CLV_PCSK_SKI1_1	1085	1089	PF00082	0.441
CLV_PCSK_SKI1_1	1107	1111	PF00082	0.478
CLV_PCSK_SKI1_1	596	600	PF00082	0.530
CLV_PCSK_SKI1_1	631	635	PF00082	0.431
CLV_PCSK_SKI1_1	725	729	PF00082	0.557
CLV_PCSK_SKI1_1	805	809	PF00082	0.589
CLV_PCSK_SKI1_1	924	928	PF00082	0.519
DEG_APCC_DBOX_1	1013	1021	PF00400	0.583
DEG_SPOP_SBC_1	742	746	PF00917	0.712
DOC_ANK_TNKS_1	71	78	PF00023	0.737
DOC_CKS1_1	256	261	PF01111	0.608
DOC_CKS1_1	680	685	PF01111	0.650
DOC_CYCLIN_RxL_1	291	304	PF00134	0.580
DOC_CYCLIN_RxL_1	94	105	PF00134	0.744
DOC_CYCLIN_yCln2_LP_2	563	569	PF00134	0.739
DOC_MAPK_gen_1	174	180	PF00069	0.597
DOC_MAPK_gen_1	356	363	PF00069	0.626
DOC_MAPK_RevD_3	1268	1283	PF00069	0.522
DOC_PP2B_LxvP_1	570	573	PF13499	0.795
DOC_USP7_MATH_1	100	104	PF00917	0.661
DOC_USP7_MATH_1	1150	1154	PF00917	0.754
DOC_USP7_MATH_1	1157	1161	PF00917	0.714
DOC_USP7_MATH_1	116	120	PF00917	0.657
DOC_USP7_MATH_1	1192	1196	PF00917	0.720
DOC_USP7_MATH_1	1251	1255	PF00917	0.600
DOC_USP7_MATH_1	30	34	PF00917	0.842
DOC_USP7_MATH_1	386	390	PF00917	0.796
DOC_USP7_MATH_1	583	587	PF00917	0.652
DOC_USP7_MATH_1	687	691	PF00917	0.613
DOC_USP7_MATH_1	742	746	PF00917	0.712
DOC_USP7_UBL2_3	1103	1107	PF12436	0.683
DOC_WW_Pin1_4	239	244	PF00397	0.636
DOC_WW_Pin1_4	255	260	PF00397	0.446
DOC_WW_Pin1_4	28	33	PF00397	0.843
DOC_WW_Pin1_4	37	42	PF00397	0.829
DOC_WW_Pin1_4	46	51	PF00397	0.689
DOC_WW_Pin1_4	490	495	PF00397	0.700
DOC_WW_Pin1_4	533	538	PF00397	0.856
DOC_WW_Pin1_4	540	545	PF00397	0.781
DOC_WW_Pin1_4	607	612	PF00397	0.757
DOC_WW_Pin1_4	679	684	PF00397	0.647
LIG_14-3-3_CanoR_1	1014	1024	PF00244	0.609
LIG_14-3-3_CanoR_1	1049	1059	PF00244	0.646
LIG_14-3-3_CanoR_1	106	112	PF00244	0.737
LIG_14-3-3_CanoR_1	1115	1121	PF00244	0.737
LIG_14-3-3_CanoR_1	1138	1145	PF00244	0.761
LIG_14-3-3_CanoR_1	118	126	PF00244	0.673
LIG_14-3-3_CanoR_1	1258	1264	PF00244	0.508
LIG_14-3-3_CanoR_1	175	181	PF00244	0.519
LIG_14-3-3_CanoR_1	274	278	PF00244	0.580
LIG_14-3-3_CanoR_1	374	380	PF00244	0.690
LIG_14-3-3_CanoR_1	428	438	PF00244	0.760
LIG_14-3-3_CanoR_1	584	591	PF00244	0.712
LIG_14-3-3_CanoR_1	699	704	PF00244	0.608
LIG_Actin_WH2_2	173	190	PF00022	0.636
LIG_BIR_III_2	883	887	PF00653	0.739
LIG_BIR_III_4	1126	1130	PF00653	0.634
LIG_BRCT_BRCA1_1	241	245	PF00533	0.636
LIG_FHA_1	122	128	PF00498	0.841
LIG_FHA_1	136	142	PF00498	0.791
LIG_FHA_1	232	238	PF00498	0.636
LIG_FHA_1	358	364	PF00498	0.666
LIG_FHA_1	378	384	PF00498	0.738
LIG_FHA_1	465	471	PF00498	0.799
LIG_FHA_1	47	53	PF00498	0.710
LIG_FHA_1	494	500	PF00498	0.626
LIG_FHA_1	508	514	PF00498	0.467
LIG_FHA_1	6	12	PF00498	0.638
LIG_FHA_1	719	725	PF00498	0.774
LIG_FHA_1	766	772	PF00498	0.760
LIG_FHA_1	792	798	PF00498	0.686
LIG_FHA_1	866	872	PF00498	0.613
LIG_FHA_1	94	100	PF00498	0.746
LIG_FHA_1	954	960	PF00498	0.651
LIG_FHA_2	1016	1022	PF00498	0.661
LIG_FHA_2	1160	1166	PF00498	0.701
LIG_FHA_2	256	262	PF00498	0.608
LIG_FHA_2	448	454	PF00498	0.753
LIG_FHA_2	533	539	PF00498	0.762
LIG_FHA_2	597	603	PF00498	0.740
LIG_FHA_2	757	763	PF00498	0.692
LIG_FHA_2	816	822	PF00498	0.708
LIG_FHA_2	852	858	PF00498	0.677
LIG_FHA_2	894	900	PF00498	0.663
LIG_GBD_Chelix_1	1009	1017	PF00786	0.429
LIG_LIR_Apic_2	496	501	PF02991	0.668
LIG_LIR_Gen_1	105	116	PF02991	0.682
LIG_LIR_Gen_1	1064	1071	PF02991	0.685
LIG_LIR_Gen_1	1262	1271	PF02991	0.427
LIG_LIR_Gen_1	1275	1284	PF02991	0.321
LIG_LIR_Gen_1	276	281	PF02991	0.580
LIG_LIR_Gen_1	602	611	PF02991	0.755
LIG_LIR_Gen_1	92	101	PF02991	0.719
LIG_LIR_Nem_3	105	111	PF02991	0.630
LIG_LIR_Nem_3	1064	1069	PF02991	0.679
LIG_LIR_Nem_3	1262	1266	PF02991	0.442
LIG_LIR_Nem_3	1275	1279	PF02991	0.379
LIG_LIR_Nem_3	276	280	PF02991	0.580
LIG_LIR_Nem_3	602	606	PF02991	0.756
LIG_LIR_Nem_3	92	98	PF02991	0.720
LIG_LYPXL_yS_3	669	672	PF13949	0.705
LIG_NRBOX	1267	1273	PF00104	0.530
LIG_PDZ_Class_2	1281	1286	PF00595	0.447
LIG_PTB_Apo_2	269	276	PF02174	0.552
LIG_RPA_C_Fungi	812	824	PF08784	0.637
LIG_SH2_CRK	108	112	PF00017	0.572
LIG_SH2_CRK	208	212	PF00017	0.530
LIG_SH2_CRK	95	99	PF00017	0.686
LIG_SH2_NCK_1	1248	1252	PF00017	0.521
LIG_SH2_SRC	277	280	PF00017	0.530
LIG_SH2_STAP1	277	281	PF00017	0.530
LIG_SH2_STAP1	95	99	PF00017	0.686
LIG_SH2_STAT3	974	977	PF00017	0.659
LIG_SH2_STAT5	217	220	PF00017	0.296
LIG_SH2_STAT5	511	514	PF00017	0.575
LIG_SH2_STAT5	95	98	PF00017	0.686
LIG_SH3_3	470	476	PF00018	0.658
LIG_SH3_3	477	483	PF00018	0.603
LIG_SH3_3	569	575	PF00018	0.792
LIG_SH3_3	646	652	PF00018	0.637
LIG_SUMO_SIM_par_1	1177	1184	PF11976	0.559
LIG_SUMO_SIM_par_1	124	132	PF11976	0.678
LIG_SUMO_SIM_par_1	1269	1275	PF11976	0.526
LIG_SUMO_SIM_par_1	96	103	PF11976	0.431
LIG_TRAF2_1	1141	1144	PF00917	0.468
LIG_TRAF2_1	1174	1177	PF00917	0.494
LIG_TRAF2_1	119	122	PF00917	0.567
LIG_TRAF2_1	1211	1214	PF00917	0.613
LIG_TRAF2_1	317	320	PF00917	0.413
LIG_TRAF2_1	759	762	PF00917	0.701
LIG_TRAF2_1	801	804	PF00917	0.569
LIG_TRAF2_1	932	935	PF00917	0.679
LIG_TRFH_1	208	212	PF08558	0.530
LIG_UBA3_1	155	160	PF00899	0.532
LIG_UBA3_1	870	878	PF00899	0.660
LIG_WRC_WIRS_1	1273	1278	PF05994	0.452
LIG_WRC_WIRS_1	249	254	PF05994	0.413
MOD_CDK_SPK_2	39	44	PF00069	0.617
MOD_CDK_SPxxK_3	37	44	PF00069	0.621
MOD_CDK_SPxxK_3	46	53	PF00069	0.516
MOD_CDK_SPxxK_3	490	497	PF00069	0.618
MOD_CK1_1	1254	1260	PF00069	0.538
MOD_CK1_1	1275	1281	PF00069	0.530
MOD_CK1_1	16	22	PF00069	0.640
MOD_CK1_1	244	250	PF00069	0.530
MOD_CK1_1	33	39	PF00069	0.771
MOD_CK1_1	377	383	PF00069	0.651
MOD_CK1_1	431	437	PF00069	0.638
MOD_CK1_1	493	499	PF00069	0.518
MOD_CK1_1	582	588	PF00069	0.696
MOD_CK1_1	653	659	PF00069	0.672
MOD_CK2_1	1015	1021	PF00069	0.509
MOD_CK2_1	1080	1086	PF00069	0.626
MOD_CK2_1	1159	1165	PF00069	0.619
MOD_CK2_1	116	122	PF00069	0.565
MOD_CK2_1	314	320	PF00069	0.452
MOD_CK2_1	406	412	PF00069	0.693
MOD_CK2_1	458	464	PF00069	0.646
MOD_CK2_1	596	602	PF00069	0.671
MOD_CK2_1	607	613	PF00069	0.517
MOD_CK2_1	682	688	PF00069	0.578
MOD_CK2_1	699	705	PF00069	0.467
MOD_CK2_1	756	762	PF00069	0.630
MOD_CK2_1	798	804	PF00069	0.568
MOD_Cter_Amidation	1226	1229	PF01082	0.582
MOD_DYRK1A_RPxSP_1	39	43	PF00069	0.621
MOD_GlcNHglycan	1035	1038	PF01048	0.611
MOD_GlcNHglycan	1152	1155	PF01048	0.724
MOD_GlcNHglycan	1168	1171	PF01048	0.442
MOD_GlcNHglycan	1189	1192	PF01048	0.573
MOD_GlcNHglycan	1194	1197	PF01048	0.533
MOD_GlcNHglycan	156	159	PF01048	0.609
MOD_GlcNHglycan	3	6	PF01048	0.633
MOD_GlcNHglycan	304	307	PF01048	0.452
MOD_GlcNHglycan	32	35	PF01048	0.817
MOD_GlcNHglycan	357	360	PF01048	0.603
MOD_GlcNHglycan	408	411	PF01048	0.766
MOD_GlcNHglycan	445	448	PF01048	0.603
MOD_GlcNHglycan	576	579	PF01048	0.807
MOD_GlcNHglycan	581	584	PF01048	0.698
MOD_GlcNHglycan	800	803	PF01048	0.552
MOD_GlcNHglycan	927	930	PF01048	0.650
MOD_GSK3_1	1	8	PF00069	0.612
MOD_GSK3_1	102	109	PF00069	0.694
MOD_GSK3_1	1155	1162	PF00069	0.581
MOD_GSK3_1	117	124	PF00069	0.772
MOD_GSK3_1	1187	1194	PF00069	0.506
MOD_GSK3_1	13	20	PF00069	0.484
MOD_GSK3_1	154	161	PF00069	0.610
MOD_GSK3_1	231	238	PF00069	0.515
MOD_GSK3_1	244	251	PF00069	0.300
MOD_GSK3_1	30	37	PF00069	0.621
MOD_GSK3_1	355	362	PF00069	0.720
MOD_GSK3_1	369	376	PF00069	0.539
MOD_GSK3_1	397	404	PF00069	0.744
MOD_GSK3_1	429	436	PF00069	0.642
MOD_GSK3_1	443	450	PF00069	0.444
MOD_GSK3_1	459	466	PF00069	0.450
MOD_GSK3_1	579	586	PF00069	0.776
MOD_GSK3_1	592	599	PF00069	0.454
MOD_GSK3_1	650	657	PF00069	0.649
MOD_GSK3_1	847	854	PF00069	0.692
MOD_GSK3_1	89	96	PF00069	0.674
MOD_LATS_1	594	600	PF00433	0.666
MOD_N-GLC_1	1064	1069	PF02516	0.591
MOD_N-GLC_1	231	236	PF02516	0.530
MOD_N-GLC_1	538	543	PF02516	0.759
MOD_N-GLC_1	953	958	PF02516	0.547
MOD_N-GLC_2	1025	1027	PF02516	0.511
MOD_N-GLC_2	1265	1267	PF02516	0.491
MOD_NEK2_1	1116	1121	PF00069	0.573
MOD_NEK2_1	1148	1153	PF00069	0.643
MOD_NEK2_1	1166	1171	PF00069	0.411
MOD_NEK2_1	1272	1277	PF00069	0.530
MOD_NEK2_1	17	22	PF00069	0.634
MOD_NEK2_1	281	286	PF00069	0.530
MOD_NEK2_1	458	463	PF00069	0.677
MOD_NEK2_1	506	511	PF00069	0.587
MOD_NEK2_1	513	518	PF00069	0.476
MOD_NEK2_1	549	554	PF00069	0.632
MOD_NEK2_1	778	783	PF00069	0.716
MOD_NEK2_2	107	112	PF00069	0.661
MOD_NEK2_2	158	163	PF00069	0.471
MOD_PIKK_1	100	106	PF00454	0.490
MOD_PIKK_1	315	321	PF00454	0.375
MOD_PIKK_1	369	375	PF00454	0.737
MOD_PIKK_1	386	392	PF00454	0.509
MOD_PIKK_1	589	595	PF00454	0.643
MOD_PIKK_1	718	724	PF00454	0.685
MOD_PIKK_1	743	749	PF00454	0.693
MOD_PIKK_1	778	784	PF00454	0.716
MOD_PIKK_1	833	839	PF00454	0.620
MOD_PIKK_1	89	95	PF00454	0.663
MOD_PKA_1	401	407	PF00069	0.736
MOD_PKA_1	428	434	PF00069	0.638
MOD_PKA_1	851	857	PF00069	0.663
MOD_PKA_2	1137	1143	PF00069	0.707
MOD_PKA_2	117	123	PF00069	0.802
MOD_PKA_2	273	279	PF00069	0.406
MOD_PKA_2	355	361	PF00069	0.682
MOD_PKA_2	373	379	PF00069	0.522
MOD_PKA_2	401	407	PF00069	0.813
MOD_PKA_2	428	434	PF00069	0.720
MOD_PKA_2	513	519	PF00069	0.583
MOD_PKA_2	526	532	PF00069	0.576
MOD_PKA_2	583	589	PF00069	0.733
MOD_PKA_2	851	857	PF00069	0.674
MOD_PKA_2	865	871	PF00069	0.473
MOD_PKB_1	399	407	PF00069	0.741
MOD_PKB_1	428	436	PF00069	0.488
MOD_PKB_1	849	857	PF00069	0.699
MOD_Plk_1	1064	1070	PF00069	0.595
MOD_Plk_1	459	465	PF00069	0.542
MOD_Plk_1	756	762	PF00069	0.630
MOD_Plk_1	954	960	PF00069	0.708
MOD_Plk_2-3	720	726	PF00069	0.722
MOD_Plk_4	122	128	PF00069	0.763
MOD_Plk_4	1251	1257	PF00069	0.592
MOD_Plk_4	241	247	PF00069	0.530
MOD_Plk_4	5	11	PF00069	0.586
MOD_Plk_4	507	513	PF00069	0.501
MOD_Plk_4	586	592	PF00069	0.606
MOD_Plk_4	602	608	PF00069	0.530
MOD_Plk_4	668	674	PF00069	0.630
MOD_ProDKin_1	239	245	PF00069	0.530
MOD_ProDKin_1	255	261	PF00069	0.265
MOD_ProDKin_1	28	34	PF00069	0.821
MOD_ProDKin_1	37	43	PF00069	0.798
MOD_ProDKin_1	46	52	PF00069	0.601
MOD_ProDKin_1	490	496	PF00069	0.620
MOD_ProDKin_1	533	539	PF00069	0.836
MOD_ProDKin_1	540	546	PF00069	0.729
MOD_ProDKin_1	607	613	PF00069	0.698
MOD_ProDKin_1	679	685	PF00069	0.549
MOD_SUMO_for_1	1211	1214	PF00179	0.613
MOD_SUMO_for_1	807	810	PF00179	0.714
MOD_SUMO_rev_2	1100	1109	PF00179	0.622
MOD_SUMO_rev_2	136	146	PF00179	0.647
MOD_SUMO_rev_2	888	896	PF00179	0.728
MOD_SUMO_rev_2	899	909	PF00179	0.593
MOD_SUMO_rev_2	918	923	PF00179	0.523
MOD_SUMO_rev_2	935	940	PF00179	0.431
TRG_DiLeu_BaEn_1	1084	1089	PF01217	0.545
TRG_DiLeu_BaEn_1	341	346	PF01217	0.452
TRG_DiLeu_BaEn_1	731	736	PF01217	0.573
TRG_DiLeu_BaEn_4	935	941	PF01217	0.571
TRG_DiLeu_BaLyEn_6	1112	1117	PF01217	0.451
TRG_DiLeu_BaLyEn_6	866	871	PF01217	0.581
TRG_ENDOCYTIC_2	108	111	PF00928	0.565
TRG_ENDOCYTIC_2	277	280	PF00928	0.475
TRG_ENDOCYTIC_2	669	672	PF00928	0.627
TRG_ENDOCYTIC_2	95	98	PF00928	0.686
TRG_ER_diArg_1	1047	1049	PF00400	0.456
TRG_ER_diArg_1	1228	1231	PF00400	0.661
TRG_ER_diArg_1	148	151	PF00400	0.577
TRG_ER_diArg_1	162	164	PF00400	0.463
TRG_ER_diArg_1	399	402	PF00400	0.753
TRG_ER_diArg_1	428	430	PF00400	0.499
TRG_ER_diArg_1	849	852	PF00400	0.729
TRG_NES_CRM1_1	612	627	PF08389	0.545
TRG_NLS_MonoExtN_4	967	973	PF00514	0.539
TRG_Pf-PMV_PEXEL_1	185	189	PF00026	0.530
TRG_Pf-PMV_PEXEL_1	336	340	PF00026	0.471
TRG_Pf-PMV_PEXEL_1	641	646	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	869	873	PF00026	0.612
TRG_Pf-PMV_PEXEL_1	921	925	PF00026	0.601

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WQP8	Leishmania donovani	89%	100%
A4H5R1	Leishmania braziliensis	55%	92%
A4HU01	Leishmania infantum	89%	100%
E9AMT1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	89%