Rhodanese domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QHN0_LEIMA

TriTrypDb:

LmjF.09.1450 , LMJLV39_090022100 , LMJSD75_090021800

Length:

131

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QHN0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QHN0

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	3
GO:0004792	thiosulfate sulfurtransferase activity	5	3
GO:0016740	transferase activity	2	3
GO:0016782	transferase activity, transferring sulphur-containing groups	3	3
GO:0016783	sulfurtransferase activity	4	3

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	118	122	PF00656	0.555
CLV_NRD_NRD_1	70	72	PF00675	0.277
CLV_NRD_NRD_1	75	77	PF00675	0.265
DOC_MAPK_gen_1	104	112	PF00069	0.574
DOC_MAPK_gen_1	76	86	PF00069	0.473
DOC_PP1_RVXF_1	105	112	PF00149	0.466
DOC_USP7_MATH_1	114	118	PF00917	0.506
DOC_USP7_UBL2_3	77	81	PF12436	0.513
LIG_14-3-3_CanoR_1	104	110	PF00244	0.506
LIG_14-3-3_CanoR_1	93	101	PF00244	0.473

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P899	Leptomonas seymouri	56%	100%
A0A0N0P8M5	Leptomonas seymouri	35%	100%
A0A1X0NHS7	Trypanosomatidae	31%	100%
A0A1X0NJI4	Trypanosomatidae	34%	96%
A0A3Q8I7K7	Leishmania donovani	100%	100%
A0A3R7LB88	Trypanosoma rangeli	27%	100%
A0A3R7MT99	Trypanosoma rangeli	27%	96%
A0A3S7WQX1	Leishmania donovani	31%	100%
A4H5X2	Leishmania braziliensis	79%	100%
A4HU67	Leishmania infantum	100%	100%

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