Sulfurtransferase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Sulfurtransferase

Gene product:

rhodanese-like domain containing protein, putative

Species:

Leishmania major

UniProt:

Q4QHM8_LEIMA

TriTrypDb:

LmjF.09.1470 , LMJLV39_090022300 , LMJSD75_090022000

Length:

119

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QHM8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QHM8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0004792	thiosulfate sulfurtransferase activity	5	8
GO:0016740	transferase activity	2	8
GO:0016782	transferase activity, transferring sulphur-containing groups	3	8
GO:0016783	sulfurtransferase activity	4	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	61	63	PF00675	0.273
DEG_Nend_UBRbox_3	1	3	PF02207	0.456
DOC_USP7_MATH_1	70	74	PF00917	0.495
DOC_USP7_MATH_1	92	96	PF00917	0.495
LIG_14-3-3_CanoR_1	62	68	PF00244	0.473
LIG_FHA_1	12	18	PF00498	0.438
LIG_FHA_1	29	35	PF00498	0.417
LIG_FHA_1	76	82	PF00498	0.504
LIG_FHA_2	55	61	PF00498	0.527
LIG_LIR_Gen_1	5	13	PF02991	0.427
LIG_LIR_Nem_3	95	101	PF02991	0.494
LIG_SH2_CRK	65	69	PF00017	0.527
LIG_SH2_STAT5	79	82	PF00017	0.443
LIG_SH3_3	40	46	PF00018	0.474
LIG_SUMO_SIM_par_1	24	33	PF11976	0.504
LIG_TRAF2_1	112	115	PF00917	0.594
MOD_CK2_1	104	110	PF00069	0.478
MOD_CK2_1	27	33	PF00069	0.439
MOD_CK2_1	54	60	PF00069	0.528
MOD_CMANNOS	108	111	PF00535	0.247
MOD_GlcNHglycan	17	20	PF01048	0.520
MOD_GlcNHglycan	65	68	PF01048	0.284
MOD_GlcNHglycan	95	98	PF01048	0.332
MOD_GSK3_1	11	18	PF00069	0.420
MOD_NEK2_1	93	98	PF00069	0.558
MOD_PKA_1	15	21	PF00069	0.542
MOD_PKA_1	63	69	PF00069	0.514
MOD_PKA_2	28	34	PF00069	0.442
MOD_SUMO_for_1	68	71	PF00179	0.527
TRG_ENDOCYTIC_2	6	9	PF00928	0.406
TRG_ENDOCYTIC_2	98	101	PF00928	0.466

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P899	Leptomonas seymouri	32%	91%
A0A0N0P8M5	Leptomonas seymouri	68%	100%
A0A0N1PG29	Leptomonas seymouri	38%	88%
A0A1X0NHS7	Trypanosomatidae	50%	100%
A0A1X0NIC3	Trypanosomatidae	49%	100%
A0A1X0NJI4	Trypanosomatidae	30%	87%
A0A1X0NJQ7	Trypanosomatidae	36%	82%
A0A3Q8I7K7	Leishmania donovani	30%	91%
A0A3R7LB88	Trypanosoma rangeli	51%	96%
A0A3R7MT99	Trypanosoma rangeli	35%	87%
A0A3R7P0U7	Trypanosoma rangeli	34%	82%
A0A3S7WQW6	Leishmania donovani	39%	79%
A0A3S7WQX1	Leishmania donovani	93%	100%
A4H5X2	Leishmania braziliensis	33%	91%
A4H5X3	Leishmania braziliensis	38%	79%
A4H5X4	Leishmania braziliensis	83%	100%
A4HU67	Leishmania infantum	30%	91%
A4HU68	Leishmania infantum	39%	79%
A4HU69	Leishmania infantum	93%	100%
D0A9P9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	87%
D0A9Q0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	83%
E9AMZ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	91%
E9AMZ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	79%
E9AMZ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
P22978	Drosophila melanogaster	42%	100%
Q08742	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	80%
Q10215	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	84%
Q12305	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	86%
Q4QHM9	Leishmania major	38%	79%
Q4QHN0	Leishmania major	30%	91%
Q8NFU3	Homo sapiens	41%	100%
Q9D0B5	Mus musculus	37%	76%
V5BI16	Trypanosoma cruzi	33%	73%
V5BMN5	Trypanosoma cruzi	37%	84%
V5BMN9	Trypanosoma cruzi	44%	96%