Leucine-rich repeat-containing protein 29

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QHM3_LEIMA

TriTrypDb:

LmjF.09.1520 , LMJLV39_090022800 , LMJSD75_090022500

Length:

338

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 18
NetGPI	no	yes: 0, no: 18

Show entries

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	19
GO:0016020	membrane	2	1
GO:0042995	cell projection	2	19
GO:0043226	organelle	2	19
GO:0043227	membrane-bounded organelle	3	19
GO:0110165	cellular anatomical entity	1	19
GO:0120025	plasma membrane bounded cell projection	3	19

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Expansion

Sequence features

Q4QHM3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QHM3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	30	32	PF00675	0.388
CLV_NRD_NRD_1	48	50	PF00675	0.493
CLV_PCSK_KEX2_1	30	32	PF00082	0.356
CLV_PCSK_KEX2_1	48	50	PF00082	0.387
CLV_PCSK_SKI1_1	161	165	PF00082	0.269
CLV_PCSK_SKI1_1	208	212	PF00082	0.346
CLV_PCSK_SKI1_1	48	52	PF00082	0.364
CLV_PCSK_SKI1_1	8	12	PF00082	0.623
CLV_Separin_Metazoa	53	57	PF03568	0.251
DEG_SCF_FBW7_1	283	288	PF00400	0.468

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I317	Leptomonas seymouri	26%	85%
A0A0N1PBA8	Leptomonas seymouri	70%	100%
A0A0S4JEI1	Bodo saltans	38%	90%
A0A1X0NI28	Trypanosomatidae	47%	100%
A0A1X0NTY3	Trypanosomatidae	26%	75%
A0A3Q8IDE6	Leishmania donovani	27%	85%
A0A3R7L7Y9	Trypanosoma rangeli	26%	76%
A0A3R7N0J2	Trypanosoma rangeli	45%	100%
A0A3S5H6F0	Leishmania donovani	95%	100%
A4H5X9	Leishmania braziliensis	87%	100%

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