Amidohydrolase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Amidohydrolase

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QHA2_LEIMA

TriTrypDb:

LmjF.10.1120 , LMJLV39_100018400 , LMJSD75_100018500

Length:

139


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Could not find GO cellular_component term for this entry.

Q4QHA2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QHA2

PDB structure(s): 7ane_aw


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	106	110	PF00656	0.485
CLV_NRD_NRD_1	49	51	PF00675	0.371
CLV_NRD_NRD_1	98	100	PF00675	0.560
CLV_PCSK_KEX2_1	30	32	PF00082	0.386
CLV_PCSK_KEX2_1	98	100	PF00082	0.518
CLV_PCSK_PC1ET2_1	30	32	PF00082	0.475
CLV_PCSK_SKI1_1	27	31	PF00082	0.430
CLV_PCSK_SKI1_1	99	103	PF00082	0.551
DOC_MAPK_DCC_7	30	38	PF00069	0.375
DOC_MAPK_gen_1	127	135	PF00069	0.413
DOC_MAPK_gen_1	30	38	PF00069	0.415
DOC_MAPK_MEF2A_6	30	38	PF00069	0.375
DOC_WW_Pin1_4	117	122	PF00397	0.419
LIG_deltaCOP1_diTrp_1	57	65	PF00928	0.404
LIG_FHA_1	9	15	PF00498	0.469
LIG_LIR_Gen_1	57	65	PF02991	0.425
LIG_LIR_Gen_1	78	86	PF02991	0.398
LIG_LIR_Gen_1	93	102	PF02991	0.368
LIG_LIR_Nem_3	120	125	PF02991	0.455
LIG_LIR_Nem_3	57	61	PF02991	0.425
LIG_LIR_Nem_3	78	83	PF02991	0.419
LIG_LIR_Nem_3	93	97	PF02991	0.360
LIG_LYPXL_yS_3	122	125	PF13949	0.420
LIG_SH2_CRK	94	98	PF00017	0.448
LIG_SH2_GRB2like	94	97	PF00017	0.443
LIG_SH2_NCK_1	80	84	PF00017	0.406
LIG_SH2_STAT5	13	16	PF00017	0.435
LIG_SH2_STAT5	80	83	PF00017	0.412
LIG_SH3_3	58	64	PF00018	0.459
MOD_GlcNHglycan	113	116	PF01048	0.569
MOD_NEK2_1	111	116	PF00069	0.536
MOD_NEK2_2	45	50	PF00069	0.357
MOD_ProDKin_1	117	123	PF00069	0.416
TRG_ENDOCYTIC_2	122	125	PF00928	0.403
TRG_ENDOCYTIC_2	80	83	PF00928	0.406
TRG_ENDOCYTIC_2	94	97	PF00928	0.366
TRG_ER_diArg_1	97	99	PF00400	0.511
TRG_NES_CRM1_1	32	46	PF08389	0.481
TRG_NLS_MonoExtC_3	22	27	PF00514	0.507
TRG_NLS_MonoExtN_4	23	28	PF00514	0.509


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5W9	Leptomonas seymouri	78%	75%
A0A0S4IQ26	Bodo saltans	56%	68%
A0A1X0NQG0	Trypanosomatidae	70%	75%
A0A3Q8I8X2	Leishmania donovani	96%	100%
A0A422NGL2	Trypanosoma rangeli	70%	74%
A4H6A0	Leishmania braziliensis	90%	100%
A4HUM4	Leishmania infantum	97%	100%
C9ZVQ5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	69%	76%
E9ANC2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%