CW-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QH90_LEIMA

TriTrypDb:

LmjF.10.1225 , LMJLV39_100019800 , LMJSD75_100019800

Length:

310

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QH90

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QH90

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	294	298	PF00656	0.854
CLV_NRD_NRD_1	74	76	PF00675	0.821
CLV_PCSK_KEX2_1	74	76	PF00082	0.821
CLV_PCSK_SKI1_1	156	160	PF00082	0.711
CLV_PCSK_SKI1_1	219	223	PF00082	0.698
CLV_PCSK_SKI1_1	270	274	PF00082	0.774
DEG_SCF_FBW7_1	29	36	PF00400	0.840
DEG_SPOP_SBC_1	199	203	PF00917	0.775
DOC_CYCLIN_RxL_1	267	274	PF00134	0.779
DOC_CYCLIN_yClb1_LxF_4	154	159	PF00134	0.719
DOC_MAPK_gen_1	64	71	PF00069	0.801
DOC_PP1_RVXF_1	154	160	PF00149	0.716
DOC_USP7_MATH_1	133	137	PF00917	0.681
DOC_USP7_MATH_1	27	31	PF00917	0.851
DOC_USP7_MATH_1	275	279	PF00917	0.804
DOC_WW_Pin1_4	150	155	PF00397	0.734
DOC_WW_Pin1_4	25	30	PF00397	0.849
LIG_14-3-3_CanoR_1	132	138	PF00244	0.683
LIG_14-3-3_CanoR_1	156	162	PF00244	0.706
LIG_Actin_WH2_2	140	158	PF00022	0.735
LIG_APCC_ABBA_1	159	164	PF00400	0.691
LIG_APCC_ABBAyCdc20_2	176	182	PF00400	0.719
LIG_CtBP_PxDLS_1	149	153	PF00389	0.741
LIG_deltaCOP1_diTrp_1	51	59	PF00928	0.823
LIG_FHA_1	124	130	PF00498	0.664
LIG_FHA_1	220	226	PF00498	0.713
LIG_FHA_1	82	88	PF00498	0.804
LIG_FHA_2	208	214	PF00498	0.701
LIG_LIR_Apic_2	228	234	PF02991	0.691
LIG_LIR_Gen_1	141	152	PF02991	0.746
LIG_LIR_Gen_1	160	168	PF02991	0.373
LIG_LIR_Nem_3	160	165	PF02991	0.699
LIG_NRP_CendR_1	308	310	PF00754	0.836
LIG_Pex14_2	211	215	PF04695	0.691
LIG_PTB_Apo_2	220	227	PF02174	0.714
LIG_PTB_Apo_2	257	264	PF02174	0.702
LIG_PTB_Phospho_1	257	263	PF10480	0.698
LIG_RPA_C_Fungi	120	132	PF08784	0.665
LIG_SH2_NCK_1	127	131	PF00017	0.660
LIG_SH2_SRC	264	267	PF00017	0.746
LIG_SH2_STAP1	127	131	PF00017	0.660
LIG_SH2_STAT3	91	94	PF00017	0.808
LIG_SH2_STAT5	252	255	PF00017	0.670
LIG_SH2_STAT5	264	267	PF00017	0.535
LIG_SH3_3	137	143	PF00018	0.703
LIG_SH3_3	253	259	PF00018	0.678
LIG_SH3_3	62	68	PF00018	0.804
LIG_SUMO_SIM_par_1	148	153	PF11976	0.746
LIG_SxIP_EBH_1	38	48	PF03271	0.838
MOD_CDK_SPxK_1	150	156	PF00069	0.734
MOD_CK1_1	22	28	PF00069	0.846
MOD_CK2_1	207	213	PF00069	0.709
MOD_Cter_Amidation	298	301	PF01082	0.842
MOD_GlcNHglycan	194	197	PF01048	0.754
MOD_GlcNHglycan	203	206	PF01048	0.611
MOD_GlcNHglycan	21	24	PF01048	0.521
MOD_GlcNHglycan	277	280	PF01048	0.811
MOD_GlcNHglycan	297	300	PF01048	0.498
MOD_GlcNHglycan	3	6	PF01048	0.795
MOD_GlcNHglycan	36	39	PF01048	0.599
MOD_GSK3_1	1	8	PF00069	0.803
MOD_GSK3_1	188	195	PF00069	0.741
MOD_GSK3_1	25	32	PF00069	0.850
MOD_GSK3_1	291	298	PF00069	0.855
MOD_N-GLC_1	25	30	PF02516	0.849
MOD_NEK2_1	1	6	PF00069	0.803
MOD_NEK2_1	138	143	PF00069	0.701
MOD_NEK2_1	14	19	PF00069	0.581
MOD_NEK2_1	157	162	PF00069	0.369
MOD_NEK2_1	200	205	PF00069	0.778
MOD_OFUCOSY	253	258	PF10250	0.672
MOD_PIKK_1	291	297	PF00454	0.856
MOD_Plk_4	133	139	PF00069	0.683
MOD_Plk_4	14	20	PF00069	0.811
MOD_Plk_4	167	173	PF00069	0.728
MOD_Plk_4	174	180	PF00069	0.601
MOD_Plk_4	183	189	PF00069	0.440
MOD_ProDKin_1	150	156	PF00069	0.734
MOD_ProDKin_1	25	31	PF00069	0.849
MOD_SUMO_for_1	280	283	PF00179	0.813
TRG_ENDOCYTIC_2	252	255	PF00928	0.670
TRG_ER_diArg_1	73	75	PF00400	0.817
TRG_Pf-PMV_PEXEL_1	270	274	PF00026	0.774
TRG_Pf-PMV_PEXEL_1	77	82	PF00026	0.811