Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QH79_LEIMA

TriTrypDb:

LmjF.11.0010 , LMJLV39_110005000 , LMJSD75_110005000

Length:

170

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QH79

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QH79

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	56	58	PF00675	0.650
CLV_NRD_NRD_1	71	73	PF00675	0.402
CLV_NRD_NRD_1	84	86	PF00675	0.450
CLV_NRD_NRD_1	92	94	PF00675	0.550
CLV_PCSK_FUR_1	72	76	PF00082	0.615
CLV_PCSK_KEX2_1	71	73	PF00082	0.543
CLV_PCSK_KEX2_1	74	76	PF00082	0.558
CLV_PCSK_KEX2_1	86	88	PF00082	0.580
CLV_PCSK_PC1ET2_1	74	76	PF00082	0.558
CLV_PCSK_PC1ET2_1	86	88	PF00082	0.446
CLV_PCSK_SKI1_1	96	100	PF00082	0.574
DEG_APCC_DBOX_1	95	103	PF00400	0.654
DEG_Nend_UBRbox_2	1	3	PF02207	0.797
DOC_CYCLIN_RxL_1	93	101	PF00134	0.568
DOC_MAPK_gen_1	4	13	PF00069	0.594
DOC_MAPK_gen_1	54	63	PF00069	0.500
DOC_MAPK_gen_1	93	102	PF00069	0.603
DOC_MAPK_MEF2A_6	93	102	PF00069	0.603
DOC_USP7_MATH_1	149	153	PF00917	0.626
DOC_USP7_MATH_1	18	22	PF00917	0.784
DOC_WW_Pin1_4	108	113	PF00397	0.562
LIG_14-3-3_CanoR_1	123	129	PF00244	0.487
LIG_14-3-3_CanoR_1	23	30	PF00244	0.686
LIG_LIR_Gen_1	115	122	PF02991	0.672
LIG_LIR_Nem_3	115	121	PF02991	0.677
LIG_PCNA_PIPBox_1	126	135	PF02747	0.606
LIG_PCNA_PIPBox_1	141	150	PF02747	0.431
LIG_PCNA_yPIPBox_3	123	133	PF02747	0.592
LIG_PCNA_yPIPBox_3	136	148	PF02747	0.377
LIG_PDZ_Class_3	165	170	PF00595	0.499
LIG_RPA_C_Fungi	28	40	PF08784	0.475
LIG_SH2_GRB2like	30	33	PF00017	0.489
LIG_SH2_NCK_1	148	152	PF00017	0.630
LIG_SH2_SRC	148	151	PF00017	0.491
LIG_SH2_STAP1	133	137	PF00017	0.640
LIG_SUMO_SIM_anti_2	59	64	PF11976	0.643
LIG_UBA3_1	161	166	PF00899	0.644
MOD_CK1_1	21	27	PF00069	0.679
MOD_CK1_1	41	47	PF00069	0.471
MOD_CK2_1	21	27	PF00069	0.604
MOD_GlcNHglycan	13	16	PF01048	0.746
MOD_GlcNHglycan	150	154	PF01048	0.598
MOD_GlcNHglycan	19	23	PF01048	0.638
MOD_GlcNHglycan	49	52	PF01048	0.508
MOD_GlcNHglycan	8	11	PF01048	0.755
MOD_N-GLC_1	47	52	PF02516	0.510
MOD_NEK2_1	11	16	PF00069	0.796
MOD_NEK2_1	98	103	PF00069	0.607
MOD_PIKK_1	122	128	PF00454	0.640
MOD_PKA_2	122	128	PF00069	0.483
MOD_Plk_1	77	83	PF00069	0.503
MOD_Plk_2-3	77	83	PF00069	0.655
MOD_ProDKin_1	108	114	PF00069	0.559
MOD_SUMO_for_1	165	168	PF00179	0.627
TRG_DiLeu_BaEn_1	95	100	PF01217	0.603
TRG_ER_diArg_1	70	72	PF00400	0.663
TRG_ER_diArg_1	84	87	PF00400	0.435
TRG_NLS_Bipartite_1	71	89	PF00514	0.459
TRG_NLS_MonoExtC_3	84	90	PF00514	0.455
TRG_Pf-PMV_PEXEL_1	33	37	PF00026	0.661
TRG_Pf-PMV_PEXEL_1	54	59	PF00026	0.652

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WRF3	Leishmania donovani	88%	100%
A4HUR3	Leishmania infantum	88%	100%
E9ANE7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%