ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA repair and recombination helicase protein PIF2, putative

Species:

Leishmania major

UniProt:

Q4QH48_LEIMA

TriTrypDb:

LmjF.11.0320 , LMJLV39_110008600 , LMJSD75_110008700

Length:

1223

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005657	replication fork	2	2
GO:0005737	cytoplasm	2	8
GO:0110165	cellular anatomical entity	1	8

Expansion

Sequence features

Q4QH48

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QH48

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	8
GO:0006139	nucleobase-containing compound metabolic process	3	8
GO:0006259	DNA metabolic process	4	8
GO:0006260	DNA replication	5	2
GO:0006281	DNA repair	5	8
GO:0006310	DNA recombination	5	8
GO:0006725	cellular aromatic compound metabolic process	3	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0006950	response to stress	2	8
GO:0006974	DNA damage response	4	8
GO:0006996	organelle organization	4	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0016043	cellular component organization	3	8
GO:0032200	telomere organization	6	8
GO:0032392	DNA geometric change	7	2
GO:0032508	DNA duplex unwinding	8	2
GO:0033554	cellular response to stress	3	8
GO:0034641	cellular nitrogen compound metabolic process	3	8
GO:0043170	macromolecule metabolic process	3	8
GO:0044237	cellular metabolic process	2	8
GO:0044238	primary metabolic process	2	8
GO:0044260	obsolete cellular macromolecule metabolic process	3	8
GO:0046483	heterocycle metabolic process	3	8
GO:0050896	response to stimulus	1	8
GO:0051276	chromosome organization	5	8
GO:0051716	cellular response to stimulus	2	8
GO:0071103	DNA conformation change	6	2
GO:0071704	organic substance metabolic process	2	8
GO:0071840	cellular component organization or biogenesis	2	8
GO:0090304	nucleic acid metabolic process	4	8
GO:1901360	organic cyclic compound metabolic process	3	8

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003678	DNA helicase activity	3	8
GO:0003824	catalytic activity	1	8
GO:0004386	helicase activity	2	8
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0008094	ATP-dependent activity, acting on DNA	2	8
GO:0016462	pyrophosphatase activity	5	8
GO:0016787	hydrolase activity	2	8
GO:0016817	hydrolase activity, acting on acid anhydrides	3	8
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	8
GO:0016887	ATP hydrolysis activity	7	8
GO:0017076	purine nucleotide binding	4	8
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:0140097	catalytic activity, acting on DNA	3	8
GO:0140640	catalytic activity, acting on a nucleic acid	2	8
GO:0140657	ATP-dependent activity	1	8
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	12	16	PF00656	0.580
CLV_C14_Caspase3-7	151	155	PF00656	0.634
CLV_C14_Caspase3-7	290	294	PF00656	0.791
CLV_C14_Caspase3-7	766	770	PF00656	0.453
CLV_C14_Caspase3-7	913	917	PF00656	0.661
CLV_NRD_NRD_1	1147	1149	PF00675	0.525
CLV_NRD_NRD_1	1152	1154	PF00675	0.532
CLV_NRD_NRD_1	1158	1160	PF00675	0.518
CLV_NRD_NRD_1	1168	1170	PF00675	0.475
CLV_NRD_NRD_1	1204	1206	PF00675	0.785
CLV_NRD_NRD_1	1207	1209	PF00675	0.687
CLV_NRD_NRD_1	217	219	PF00675	0.684
CLV_NRD_NRD_1	337	339	PF00675	0.613
CLV_NRD_NRD_1	552	554	PF00675	0.342
CLV_NRD_NRD_1	583	585	PF00675	0.375
CLV_NRD_NRD_1	621	623	PF00675	0.478
CLV_NRD_NRD_1	649	651	PF00675	0.452
CLV_NRD_NRD_1	736	738	PF00675	0.705
CLV_NRD_NRD_1	812	814	PF00675	0.533
CLV_NRD_NRD_1	839	841	PF00675	0.706
CLV_NRD_NRD_1	982	984	PF00675	0.512
CLV_PCSK_FUR_1	1205	1209	PF00082	0.711
CLV_PCSK_KEX2_1	1147	1149	PF00082	0.498
CLV_PCSK_KEX2_1	1152	1154	PF00082	0.540
CLV_PCSK_KEX2_1	1160	1162	PF00082	0.557
CLV_PCSK_KEX2_1	1167	1169	PF00082	0.352
CLV_PCSK_KEX2_1	1206	1208	PF00082	0.697
CLV_PCSK_KEX2_1	231	233	PF00082	0.731
CLV_PCSK_KEX2_1	316	318	PF00082	0.745
CLV_PCSK_KEX2_1	337	339	PF00082	0.568
CLV_PCSK_KEX2_1	552	554	PF00082	0.342
CLV_PCSK_KEX2_1	583	585	PF00082	0.358
CLV_PCSK_KEX2_1	621	623	PF00082	0.478
CLV_PCSK_KEX2_1	649	651	PF00082	0.452
CLV_PCSK_KEX2_1	735	737	PF00082	0.713
CLV_PCSK_KEX2_1	812	814	PF00082	0.533
CLV_PCSK_KEX2_1	839	841	PF00082	0.663
CLV_PCSK_KEX2_1	90	92	PF00082	0.747
CLV_PCSK_PC1ET2_1	1160	1162	PF00082	0.663
CLV_PCSK_PC1ET2_1	1167	1169	PF00082	0.585
CLV_PCSK_PC1ET2_1	1206	1208	PF00082	0.697
CLV_PCSK_PC1ET2_1	231	233	PF00082	0.736
CLV_PCSK_PC1ET2_1	316	318	PF00082	0.745
CLV_PCSK_PC1ET2_1	90	92	PF00082	0.674
CLV_PCSK_PC7_1	1148	1154	PF00082	0.569
CLV_PCSK_PC7_1	86	92	PF00082	0.723
CLV_PCSK_SKI1_1	1155	1159	PF00082	0.585
CLV_PCSK_SKI1_1	1192	1196	PF00082	0.650
CLV_PCSK_SKI1_1	228	232	PF00082	0.721
CLV_PCSK_SKI1_1	338	342	PF00082	0.534
CLV_PCSK_SKI1_1	468	472	PF00082	0.561
CLV_PCSK_SKI1_1	502	506	PF00082	0.340
CLV_PCSK_SKI1_1	507	511	PF00082	0.340
CLV_PCSK_SKI1_1	572	576	PF00082	0.422
CLV_PCSK_SKI1_1	59	63	PF00082	0.545
CLV_PCSK_SKI1_1	922	926	PF00082	0.586
CLV_PCSK_SKI1_1	960	964	PF00082	0.413
DEG_Nend_UBRbox_3	1	3	PF02207	0.503
DEG_SCF_FBW7_2	300	306	PF00400	0.596
DEG_SPOP_SBC_1	690	694	PF00917	0.564
DEG_SPOP_SBC_1	845	849	PF00917	0.714
DOC_CDC14_PxL_1	773	781	PF14671	0.480
DOC_CKS1_1	300	305	PF01111	0.593
DOC_CKS1_1	945	950	PF01111	0.614
DOC_CYCLIN_RxL_1	90	101	PF00134	0.714
DOC_CYCLIN_yClb5_NLxxxL_5	373	379	PF00134	0.623
DOC_CYCLIN_yClb5_NLxxxL_5	962	971	PF00134	0.479
DOC_CYCLIN_yCln2_LP_2	779	782	PF00134	0.603
DOC_CYCLIN_yCln2_LP_2	949	955	PF00134	0.515
DOC_MAPK_DCC_7	795	804	PF00069	0.598
DOC_MAPK_DCC_7	871	880	PF00069	0.601
DOC_MAPK_gen_1	1099	1108	PF00069	0.462
DOC_MAPK_gen_1	337	347	PF00069	0.586
DOC_MAPK_gen_1	430	437	PF00069	0.693
DOC_MAPK_gen_1	621	629	PF00069	0.437
DOC_MAPK_gen_1	649	657	PF00069	0.528
DOC_MAPK_gen_1	90	97	PF00069	0.707
DOC_MAPK_JIP1_4	951	957	PF00069	0.576
DOC_MAPK_MEF2A_6	348	357	PF00069	0.504
DOC_MAPK_MEF2A_6	430	437	PF00069	0.693
DOC_MAPK_MEF2A_6	515	522	PF00069	0.356
DOC_MAPK_MEF2A_6	621	629	PF00069	0.490
DOC_MAPK_MEF2A_6	649	657	PF00069	0.486
DOC_MAPK_MEF2A_6	795	804	PF00069	0.627
DOC_MAPK_RevD_3	800	813	PF00069	0.567
DOC_PP1_RVXF_1	381	387	PF00149	0.518
DOC_PP1_RVXF_1	657	664	PF00149	0.626
DOC_PP2B_LxvP_1	655	658	PF13499	0.537
DOC_PP2B_LxvP_1	779	782	PF13499	0.603
DOC_PP4_FxxP_1	1017	1020	PF00568	0.518
DOC_PP4_FxxP_1	312	315	PF00568	0.723
DOC_USP7_MATH_1	104	108	PF00917	0.716
DOC_USP7_MATH_1	186	190	PF00917	0.642
DOC_USP7_MATH_1	211	215	PF00917	0.731
DOC_USP7_MATH_1	230	234	PF00917	0.562
DOC_USP7_MATH_1	238	242	PF00917	0.676
DOC_USP7_MATH_1	279	283	PF00917	0.738
DOC_USP7_MATH_1	308	312	PF00917	0.635
DOC_USP7_MATH_1	324	328	PF00917	0.713
DOC_USP7_MATH_1	457	461	PF00917	0.705
DOC_USP7_MATH_1	713	717	PF00917	0.804
DOC_USP7_MATH_1	844	848	PF00917	0.739
DOC_USP7_MATH_1	851	855	PF00917	0.673
DOC_USP7_MATH_2	411	417	PF00917	0.550
DOC_USP7_UBL2_3	801	805	PF12436	0.580
DOC_WW_Pin1_4	1207	1212	PF00397	0.716
DOC_WW_Pin1_4	1217	1222	PF00397	0.638
DOC_WW_Pin1_4	299	304	PF00397	0.728
DOC_WW_Pin1_4	34	39	PF00397	0.754
DOC_WW_Pin1_4	542	547	PF00397	0.499
DOC_WW_Pin1_4	723	728	PF00397	0.797
DOC_WW_Pin1_4	786	791	PF00397	0.491
DOC_WW_Pin1_4	944	949	PF00397	0.613
LIG_14-3-3_CanoR_1	1152	1158	PF00244	0.629
LIG_14-3-3_CanoR_1	1205	1211	PF00244	0.698
LIG_14-3-3_CanoR_1	144	152	PF00244	0.678
LIG_14-3-3_CanoR_1	250	257	PF00244	0.832
LIG_14-3-3_CanoR_1	383	387	PF00244	0.536
LIG_14-3-3_CanoR_1	401	408	PF00244	0.508
LIG_14-3-3_CanoR_1	718	727	PF00244	0.730
LIG_14-3-3_CanoR_1	824	829	PF00244	0.714
LIG_Actin_WH2_2	567	585	PF00022	0.375
LIG_APCC_ABBA_1	700	705	PF00400	0.744
LIG_APCC_ABBA_1	924	929	PF00400	0.661
LIG_BIR_III_2	154	158	PF00653	0.569
LIG_BRCT_BRCA1_1	599	603	PF00533	0.410
LIG_BRCT_BRCA1_1	616	620	PF00533	0.290
LIG_BRCT_BRCA1_1	659	663	PF00533	0.631
LIG_BRCT_BRCA1_1	853	857	PF00533	0.768
LIG_CSL_BTD_1	787	790	PF09270	0.548
LIG_CtBP_PxDLS_1	1058	1062	PF00389	0.467
LIG_CtBP_PxDLS_1	781	785	PF00389	0.609
LIG_FHA_1	1036	1042	PF00498	0.448
LIG_FHA_1	126	132	PF00498	0.657
LIG_FHA_1	138	144	PF00498	0.685
LIG_FHA_1	204	210	PF00498	0.679
LIG_FHA_1	318	324	PF00498	0.738
LIG_FHA_1	334	340	PF00498	0.474
LIG_FHA_1	347	353	PF00498	0.467
LIG_FHA_1	359	365	PF00498	0.614
LIG_FHA_1	523	529	PF00498	0.340
LIG_FHA_1	614	620	PF00498	0.482
LIG_FHA_1	70	76	PF00498	0.545
LIG_FHA_1	702	708	PF00498	0.766
LIG_FHA_1	723	729	PF00498	0.805
LIG_FHA_1	760	766	PF00498	0.625
LIG_FHA_1	789	795	PF00498	0.412
LIG_FHA_1	804	810	PF00498	0.476
LIG_FHA_1	90	96	PF00498	0.676
LIG_FHA_2	113	119	PF00498	0.602
LIG_FHA_2	149	155	PF00498	0.608
LIG_FHA_2	244	250	PF00498	0.794
LIG_FHA_2	358	364	PF00498	0.606
LIG_FHA_2	365	371	PF00498	0.562
LIG_FHA_2	440	446	PF00498	0.754
LIG_FHA_2	469	475	PF00498	0.525
LIG_FHA_2	751	757	PF00498	0.514
LIG_FHA_2	758	764	PF00498	0.548
LIG_FHA_2	931	937	PF00498	0.504
LIG_Integrin_isoDGR_2	1028	1030	PF01839	0.570
LIG_IRF3_LxIS_1	538	545	PF10401	0.499
LIG_LIR_Apic_2	1014	1020	PF02991	0.525
LIG_LIR_Apic_2	309	315	PF02991	0.764
LIG_LIR_Gen_1	208	217	PF02991	0.739
LIG_LIR_Gen_1	557	567	PF02991	0.369
LIG_LIR_Gen_1	573	582	PF02991	0.269
LIG_LIR_Gen_1	600	611	PF02991	0.346
LIG_LIR_Nem_3	1009	1013	PF02991	0.451
LIG_LIR_Nem_3	208	213	PF02991	0.740
LIG_LIR_Nem_3	385	389	PF02991	0.551
LIG_LIR_Nem_3	51	57	PF02991	0.718
LIG_LIR_Nem_3	557	562	PF02991	0.369
LIG_LIR_Nem_3	573	578	PF02991	0.269
LIG_LIR_Nem_3	600	606	PF02991	0.384
LIG_LYPXL_S_1	875	879	PF13949	0.592
LIG_MYND_1	777	781	PF01753	0.596
LIG_PCNA_yPIPBox_3	680	691	PF02747	0.626
LIG_PCNA_yPIPBox_3	973	984	PF02747	0.463
LIG_Pex14_1	788	792	PF04695	0.465
LIG_Pex14_2	620	624	PF04695	0.413
LIG_PTB_Apo_2	1043	1050	PF02174	0.521
LIG_SH2_CRK	222	226	PF00017	0.581
LIG_SH2_CRK	559	563	PF00017	0.375
LIG_SH2_NCK_1	210	214	PF00017	0.669
LIG_SH2_SRC	210	213	PF00017	0.670
LIG_SH2_STAP1	1007	1011	PF00017	0.433
LIG_SH2_STAP1	1063	1067	PF00017	0.380
LIG_SH2_STAP1	139	143	PF00017	0.675
LIG_SH2_STAP1	559	563	PF00017	0.375
LIG_SH2_STAT5	1010	1013	PF00017	0.447
LIG_SH2_STAT5	1094	1097	PF00017	0.380
LIG_SH2_STAT5	1165	1168	PF00017	0.611
LIG_SH2_STAT5	139	142	PF00017	0.660
LIG_SH2_STAT5	493	496	PF00017	0.340
LIG_SH2_STAT5	792	795	PF00017	0.515
LIG_SH2_STAT5	814	817	PF00017	0.458
LIG_SH2_STAT5	819	822	PF00017	0.551
LIG_SH2_STAT5	904	907	PF00017	0.600
LIG_SH2_STAT5	943	946	PF00017	0.422
LIG_SH2_STAT5	993	996	PF00017	0.529
LIG_SH3_3	1017	1023	PF00018	0.432
LIG_SH3_3	1030	1036	PF00018	0.369
LIG_SH3_3	1097	1103	PF00018	0.410
LIG_SH3_3	381	387	PF00018	0.582
LIG_SH3_3	405	411	PF00018	0.650
LIG_SH3_3	71	77	PF00018	0.665
LIG_SH3_3	724	730	PF00018	0.781
LIG_SH3_3	871	877	PF00018	0.516
LIG_SH3_3	884	890	PF00018	0.337
LIG_SUMO_SIM_anti_2	349	354	PF11976	0.546
LIG_SUMO_SIM_anti_2	560	566	PF11976	0.340
LIG_SUMO_SIM_par_1	560	566	PF11976	0.340
LIG_TRAF2_1	200	203	PF00917	0.666
LIG_TRAF2_1	39	42	PF00917	0.712
LIG_UBA3_1	461	468	PF00899	0.710
LIG_UBA3_1	505	510	PF00899	0.429
LIG_WRC_WIRS_1	1108	1113	PF05994	0.480
LIG_WRC_WIRS_1	772	777	PF05994	0.521
LIG_WRC_WIRS_1	804	809	PF05994	0.604
MOD_CDK_SPxK_1	1207	1213	PF00069	0.675
MOD_CDK_SPxK_1	723	729	PF00069	0.566
MOD_CDK_SPxxK_3	944	951	PF00069	0.621
MOD_CK1_1	1107	1113	PF00069	0.529
MOD_CK1_1	1175	1181	PF00069	0.662
MOD_CK1_1	189	195	PF00069	0.738
MOD_CK1_1	32	38	PF00069	0.583
MOD_CK1_1	346	352	PF00069	0.501
MOD_CK1_1	568	574	PF00069	0.363
MOD_CK1_1	69	75	PF00069	0.543
MOD_CK1_1	692	698	PF00069	0.661
MOD_CK1_1	716	722	PF00069	0.804
MOD_CK1_1	827	833	PF00069	0.740
MOD_CK1_1	847	853	PF00069	0.458
MOD_CK1_1	869	875	PF00069	0.567
MOD_CK1_1	975	981	PF00069	0.448
MOD_CK2_1	112	118	PF00069	0.688
MOD_CK2_1	150	156	PF00069	0.765
MOD_CK2_1	197	203	PF00069	0.699
MOD_CK2_1	249	255	PF00069	0.725
MOD_CK2_1	357	363	PF00069	0.617
MOD_CK2_1	364	370	PF00069	0.549
MOD_CK2_1	439	445	PF00069	0.726
MOD_CK2_1	457	463	PF00069	0.779
MOD_CK2_1	750	756	PF00069	0.469
MOD_CK2_1	757	763	PF00069	0.478
MOD_CK2_1	835	841	PF00069	0.528
MOD_CK2_1	864	870	PF00069	0.637
MOD_GlcNHglycan	1200	1203	PF01048	0.740
MOD_GlcNHglycan	133	136	PF01048	0.683
MOD_GlcNHglycan	164	167	PF01048	0.688
MOD_GlcNHglycan	186	189	PF01048	0.700
MOD_GlcNHglycan	281	284	PF01048	0.807
MOD_GlcNHglycan	30	34	PF01048	0.757
MOD_GlcNHglycan	4	7	PF01048	0.689
MOD_GlcNHglycan	415	418	PF01048	0.590
MOD_GlcNHglycan	448	451	PF01048	0.771
MOD_GlcNHglycan	599	602	PF01048	0.429
MOD_GlcNHglycan	720	723	PF01048	0.792
MOD_GlcNHglycan	833	836	PF01048	0.770
MOD_GlcNHglycan	853	856	PF01048	0.438
MOD_GSK3_1	1044	1051	PF00069	0.511
MOD_GSK3_1	1107	1114	PF00069	0.478
MOD_GSK3_1	112	119	PF00069	0.641
MOD_GSK3_1	1142	1149	PF00069	0.546
MOD_GSK3_1	144	151	PF00069	0.627
MOD_GSK3_1	453	460	PF00069	0.787
MOD_GSK3_1	689	696	PF00069	0.693
MOD_GSK3_1	703	710	PF00069	0.795
MOD_GSK3_1	718	725	PF00069	0.586
MOD_GSK3_1	780	787	PF00069	0.499
MOD_GSK3_1	823	830	PF00069	0.625
MOD_GSK3_1	831	838	PF00069	0.616
MOD_GSK3_1	847	854	PF00069	0.695
MOD_LATS_1	1204	1210	PF00433	0.670
MOD_LATS_1	626	632	PF00433	0.388
MOD_N-GLC_1	2	7	PF02516	0.553
MOD_N-GLC_1	318	323	PF02516	0.561
MOD_N-GLC_1	423	428	PF02516	0.566
MOD_N-GLC_1	585	590	PF02516	0.258
MOD_N-GLC_1	855	860	PF02516	0.715
MOD_N-GLC_1	972	977	PF02516	0.454
MOD_NEK2_1	1081	1086	PF00069	0.413
MOD_NEK2_1	1106	1111	PF00069	0.426
MOD_NEK2_1	112	117	PF00069	0.719
MOD_NEK2_1	1125	1130	PF00069	0.406
MOD_NEK2_1	184	189	PF00069	0.607
MOD_NEK2_1	614	619	PF00069	0.427
MOD_NEK2_1	691	696	PF00069	0.583
MOD_NEK2_1	707	712	PF00069	0.588
MOD_NEK2_1	784	789	PF00069	0.584
MOD_NEK2_1	938	943	PF00069	0.580
MOD_NEK2_1	962	967	PF00069	0.494
MOD_NEK2_2	1063	1068	PF00069	0.389
MOD_NEK2_2	343	348	PF00069	0.582
MOD_NEK2_2	534	539	PF00069	0.375
MOD_NEK2_2	713	718	PF00069	0.808
MOD_PIKK_1	1130	1136	PF00454	0.597
MOD_PIKK_1	186	192	PF00454	0.706
MOD_PIKK_1	528	534	PF00454	0.413
MOD_PIKK_1	716	722	PF00454	0.760
MOD_PIKK_1	824	830	PF00454	0.679
MOD_PIKK_1	938	944	PF00454	0.462
MOD_PK_1	1000	1006	PF00069	0.594
MOD_PK_1	736	742	PF00069	0.650
MOD_PKA_1	1147	1153	PF00069	0.563
MOD_PKA_1	1206	1212	PF00069	0.709
MOD_PKA_1	736	742	PF00069	0.650
MOD_PKA_2	1146	1152	PF00069	0.670
MOD_PKA_2	1198	1204	PF00069	0.727
MOD_PKA_2	1206	1212	PF00069	0.531
MOD_PKA_2	249	255	PF00069	0.794
MOD_PKA_2	358	364	PF00069	0.602
MOD_PKA_2	382	388	PF00069	0.545
MOD_PKA_2	413	419	PF00069	0.551
MOD_PKA_2	446	452	PF00069	0.688
MOD_PKA_2	736	742	PF00069	0.731
MOD_PKA_2	823	829	PF00069	0.746
MOD_PKA_2	831	837	PF00069	0.641
MOD_Plk_1	1000	1006	PF00069	0.577
MOD_Plk_1	1081	1087	PF00069	0.418
MOD_Plk_1	112	118	PF00069	0.688
MOD_Plk_1	1125	1131	PF00069	0.441
MOD_Plk_1	148	154	PF00069	0.669
MOD_Plk_1	196	202	PF00069	0.787
MOD_Plk_1	2	8	PF00069	0.556
MOD_Plk_1	318	324	PF00069	0.666
MOD_Plk_1	423	429	PF00069	0.557
MOD_Plk_1	50	56	PF00069	0.552
MOD_Plk_1	554	560	PF00069	0.380
MOD_Plk_1	565	571	PF00069	0.290
MOD_Plk_1	69	75	PF00069	0.543
MOD_Plk_1	713	719	PF00069	0.805
MOD_Plk_1	869	875	PF00069	0.543
MOD_Plk_1	936	942	PF00069	0.552
MOD_Plk_2-3	197	203	PF00069	0.775
MOD_Plk_2-3	249	255	PF00069	0.716
MOD_Plk_2-3	555	561	PF00069	0.429
MOD_Plk_2-3	66	72	PF00069	0.705
MOD_Plk_4	1000	1006	PF00069	0.568
MOD_Plk_4	1071	1077	PF00069	0.437
MOD_Plk_4	1111	1117	PF00069	0.468
MOD_Plk_4	112	118	PF00069	0.667
MOD_Plk_4	1153	1159	PF00069	0.630
MOD_Plk_4	457	463	PF00069	0.718
MOD_Plk_4	489	495	PF00069	0.358
MOD_Plk_4	500	506	PF00069	0.311
MOD_Plk_4	565	571	PF00069	0.340
MOD_Plk_4	615	621	PF00069	0.476
MOD_Plk_4	628	634	PF00069	0.447
MOD_Plk_4	780	786	PF00069	0.498
MOD_Plk_4	788	794	PF00069	0.384
MOD_Plk_4	975	981	PF00069	0.448
MOD_ProDKin_1	1207	1213	PF00069	0.719
MOD_ProDKin_1	1217	1223	PF00069	0.641
MOD_ProDKin_1	299	305	PF00069	0.728
MOD_ProDKin_1	34	40	PF00069	0.754
MOD_ProDKin_1	542	548	PF00069	0.499
MOD_ProDKin_1	723	729	PF00069	0.798
MOD_ProDKin_1	786	792	PF00069	0.486
MOD_ProDKin_1	944	950	PF00069	0.609
MOD_SUMO_for_1	1011	1014	PF00179	0.520
MOD_SUMO_rev_2	1185	1194	PF00179	0.648
MOD_SUMO_rev_2	460	470	PF00179	0.682
MOD_SUMO_rev_2	58	64	PF00179	0.545
TRG_DiLeu_BaEn_1	326	331	PF01217	0.600
TRG_DiLeu_BaEn_3	896	902	PF01217	0.536
TRG_DiLeu_BaEn_4	196	202	PF01217	0.717
TRG_DiLeu_BaLyEn_6	1184	1189	PF01217	0.552
TRG_DiLeu_BaLyEn_6	398	403	PF01217	0.536
TRG_DiLeu_BaLyEn_6	610	615	PF01217	0.518
TRG_ENDOCYTIC_2	1094	1097	PF00928	0.380
TRG_ENDOCYTIC_2	210	213	PF00928	0.670
TRG_ENDOCYTIC_2	332	335	PF00928	0.445
TRG_ENDOCYTIC_2	396	399	PF00928	0.480
TRG_ENDOCYTIC_2	54	57	PF00928	0.718
TRG_ENDOCYTIC_2	559	562	PF00928	0.375
TRG_ENDOCYTIC_2	876	879	PF00928	0.473
TRG_ER_diArg_1	1146	1148	PF00400	0.529
TRG_ER_diArg_1	1158	1161	PF00400	0.550
TRG_ER_diArg_1	1205	1208	PF00400	0.672
TRG_ER_diArg_1	143	146	PF00400	0.655
TRG_ER_diArg_1	337	339	PF00400	0.613
TRG_ER_diArg_1	582	584	PF00400	0.375
TRG_ER_diArg_1	620	622	PF00400	0.462
TRG_ER_diArg_1	648	650	PF00400	0.437
TRG_ER_diArg_1	734	737	PF00400	0.712
TRG_ER_diArg_1	811	813	PF00400	0.531
TRG_ER_diArg_1	885	888	PF00400	0.448
TRG_ER_diArg_1	919	922	PF00400	0.552
TRG_NES_CRM1_1	1071	1082	PF08389	0.419
TRG_NLS_Bipartite_1	1152	1171	PF00514	0.611
TRG_NLS_Bipartite_1	218	232	PF00514	0.814
TRG_NLS_MonoCore_2	1204	1209	PF00514	0.669
TRG_NLS_MonoExtC_3	227	232	PF00514	0.784
TRG_NLS_MonoExtN_4	1152	1157	PF00514	0.634
TRG_NLS_MonoExtN_4	1205	1210	PF00514	0.712
TRG_NLS_MonoExtN_4	225	232	PF00514	0.827
TRG_Pf-PMV_PEXEL_1	1187	1191	PF00026	0.550
TRG_Pf-PMV_PEXEL_1	17	21	PF00026	0.758
TRG_Pf-PMV_PEXEL_1	25	30	PF00026	0.640
TRG_Pf-PMV_PEXEL_1	373	378	PF00026	0.543
TRG_Pf-PMV_PEXEL_1	401	405	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	507	511	PF00026	0.429
TRG_Pf-PMV_PEXEL_1	572	576	PF00026	0.422
TRG_Pf-PMV_PEXEL_1	93	98	PF00026	0.716
TRG_Pf-PMV_PEXEL_1	983	988	PF00026	0.534

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIS5	Leptomonas seymouri	63%	90%
A0A3R7MZY3	Trypanosoma rangeli	43%	100%
A0A3S7WRJ2	Leishmania donovani	93%	100%
A4H6E9	Leishmania braziliensis	79%	100%
A4HUU3	Leishmania infantum	93%	81%
E9ANH8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%