Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

Q4QGX3_LEIMA

TriTrypDb:

LmjF.11.1070 , LMJLV39_110018300 , LMJSD75_110018800

Length:

239

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGX3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGX3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	20	22	PF00675	0.625
CLV_PCSK_KEX2_1	19	21	PF00082	0.657
CLV_PCSK_SKI1_1	21	25	PF00082	0.725
DEG_APCC_DBOX_1	19	27	PF00400	0.664
DOC_CYCLIN_yCln2_LP_2	48	54	PF00134	0.640
DOC_MAPK_gen_1	19	28	PF00069	0.602
DOC_USP7_MATH_1	109	113	PF00917	0.832
DOC_USP7_MATH_1	37	41	PF00917	0.553
DOC_USP7_MATH_1	87	91	PF00917	0.797
DOC_USP7_UBL2_3	131	135	PF12436	0.660
DOC_USP7_UBL2_3	85	89	PF12436	0.809
DOC_WW_Pin1_4	151	156	PF00397	0.718
DOC_WW_Pin1_4	96	101	PF00397	0.740
LIG_14-3-3_CanoR_1	102	106	PF00244	0.782
LIG_14-3-3_CanoR_1	223	227	PF00244	0.740
LIG_14-3-3_CanoR_1	41	47	PF00244	0.753
LIG_BIR_II_1	1	5	PF00653	0.840
LIG_FHA_1	102	108	PF00498	0.814
LIG_FHA_1	152	158	PF00498	0.763
LIG_FHA_1	205	211	PF00498	0.693
LIG_FHA_1	22	28	PF00498	0.719
LIG_FHA_1	43	49	PF00498	0.606
LIG_FHA_2	72	78	PF00498	0.762
LIG_LIR_Nem_3	97	101	PF02991	0.738
LIG_PCNA_yPIPBox_3	25	39	PF02747	0.582
LIG_SH2_CRK	98	102	PF00017	0.762
LIG_SH3_3	143	149	PF00018	0.772
LIG_SUMO_SIM_anti_2	118	126	PF11976	0.672
LIG_SUMO_SIM_par_1	206	212	PF11976	0.692
LIG_TRAF2_1	111	114	PF00917	0.825
LIG_TRAF2_1	127	130	PF00917	0.716
LIG_TRAF2_1	165	168	PF00917	0.711
LIG_TRAF2_1	59	62	PF00917	0.736
LIG_TYR_ITIM	96	101	PF00017	0.740
MOD_CDC14_SPxK_1	99	102	PF00782	0.626
MOD_CDK_SPxK_1	96	102	PF00069	0.747
MOD_CDK_SPxxK_3	151	158	PF00069	0.763
MOD_CK1_1	141	147	PF00069	0.706
MOD_CK1_1	225	231	PF00069	0.659
MOD_CK1_1	90	96	PF00069	0.609
MOD_CK2_1	1	7	PF00069	0.747
MOD_CK2_1	109	115	PF00069	0.686
MOD_CK2_1	141	147	PF00069	0.841
MOD_CK2_1	71	77	PF00069	0.716
MOD_GlcNHglycan	141	144	PF01048	0.687
MOD_GlcNHglycan	195	198	PF01048	0.723
MOD_GlcNHglycan	227	231	PF01048	0.741
MOD_GlcNHglycan	68	71	PF01048	0.822
MOD_GlcNHglycan	88	92	PF01048	0.651
MOD_GSK3_1	147	154	PF00069	0.693
MOD_GSK3_1	222	229	PF00069	0.741
MOD_GSK3_1	90	97	PF00069	0.616
MOD_N-GLC_1	139	144	PF02516	0.693
MOD_NEK2_1	1	6	PF00069	0.839
MOD_NEK2_1	138	143	PF00069	0.831
MOD_NEK2_1	226	231	PF00069	0.770
MOD_PIKK_1	209	215	PF00454	0.688
MOD_PIKK_1	232	238	PF00454	0.740
MOD_PKA_2	101	107	PF00069	0.784
MOD_PKA_2	222	228	PF00069	0.719
MOD_PKB_1	19	27	PF00069	0.678
MOD_Plk_2-3	147	153	PF00069	0.703
MOD_Plk_2-3	222	228	PF00069	0.741
MOD_Plk_4	90	96	PF00069	0.669
MOD_ProDKin_1	151	157	PF00069	0.714
MOD_ProDKin_1	96	102	PF00069	0.747
MOD_SUMO_rev_2	123	133	PF00179	0.664
TRG_ENDOCYTIC_2	98	101	PF00928	0.756
TRG_ER_diArg_1	18	21	PF00400	0.643

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IHI7	Leishmania donovani	85%	100%
E9ANQ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	74%	100%