Putative 40S ribosomal protein S15A

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S15A, putative

Species:

Leishmania major

UniProt:

Q4QGW3_LEIMA

TriTrypDb:

LmjF.11.1190 , LMJLV39_110019400 , LMJSD75_290025600

Length:

130

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 40S ribosomal S15A

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 40

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005840	ribosome	5	12
GO:0015935	small ribosomal subunit	4	2
GO:0022627	cytosolic small ribosomal subunit	5	2
GO:0032991	protein-containing complex	1	14
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0044391	ribosomal subunit	3	2

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Expansion

Sequence features

Q4QGW3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGW3

Function

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Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	14
GO:0006518	peptide metabolic process	4	14
GO:0006807	nitrogen compound metabolic process	2	14
GO:0008152	metabolic process	1	14
GO:0009058	biosynthetic process	2	14
GO:0009059	macromolecule biosynthetic process	4	14
GO:0009987	cellular process	1	14
GO:0019538	protein metabolic process	3	14
GO:0034641	cellular nitrogen compound metabolic process	3	14
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	14

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Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	14
GO:0005198	structural molecule activity	1	14

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	19	21	PF00675	0.253
CLV_PCSK_FUR_1	20	24	PF00082	0.253
CLV_PCSK_KEX2_1	19	21	PF00082	0.253
CLV_PCSK_KEX2_1	22	24	PF00082	0.253
CLV_PCSK_PC1ET2_1	22	24	PF00082	0.253
CLV_PCSK_SKI1_1	23	27	PF00082	0.253
CLV_PCSK_SKI1_1	88	92	PF00082	0.273
DEG_SPOP_SBC_1	103	107	PF00917	0.453
DOC_MAPK_gen_1	19	27	PF00069	0.453
DOC_MAPK_gen_1	57	65	PF00069	0.453

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0S4J0M6	Bodo saltans	89%	100%
A0A0S4KI65	Bodo saltans	89%	85%
A0A1X0P063	Trypanosomatidae	95%	100%
A0A3Q8IFF7	Leishmania donovani	100%	100%
A0A3R7NIE4	Trypanosoma rangeli	95%	100%
A0B9V5	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	46%	100%
A0RVY8	Cenarchaeum symbiosum (strain A)	41%	100%
A1KRI7	Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)	27%	100%
A1RVN1	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	45%	100%
A1RWS0	Thermofilum pendens (strain DSM 2475 / Hrk 5)	48%	100%

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