Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QGV1_LEIMA

TriTrypDb:

LmjF.11.1310 , LMJLV39_110020500 , LMJSD75_110021000

Length:

402

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005930	axoneme	2	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

Q4QGV1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGV1

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	278	280	PF00675	0.485
CLV_NRD_NRD_1	61	63	PF00675	0.449
CLV_NRD_NRD_1	7	9	PF00675	0.546
CLV_PCSK_KEX2_1	278	280	PF00082	0.502
CLV_PCSK_KEX2_1	6	8	PF00082	0.527
CLV_PCSK_KEX2_1	61	63	PF00082	0.434
CLV_PCSK_KEX2_1	86	88	PF00082	0.508
CLV_PCSK_PC1ET2_1	86	88	PF00082	0.503
CLV_PCSK_SKI1_1	133	137	PF00082	0.565
CLV_PCSK_SKI1_1	180	184	PF00082	0.448

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVS3	Leptomonas seymouri	64%	99%
A0A0S4KKN0	Bodo saltans	33%	100%
A0A1X0NUU6	Trypanosomatidae	37%	100%
A0A3R7M4V0	Trypanosoma rangeli	37%	100%
A0A3S7WRS2	Leishmania donovani	95%	100%
A4H6Q2	Leishmania braziliensis	80%	100%
A4HV37	Leishmania infantum	95%	100%
D0A7B4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	76%
E9ANR8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
V5BWJ3	Trypanosoma cruzi	36%	100%

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