PITH domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

PITH domain-containing protein

Species:

Leishmania major

UniProt:

Q4QGU2_LEIMA

TriTrypDb:

LmjF.12.0020 , LMJLV39_120005200 , LMJSD75_120006000

Length:

215


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

Q4QGU2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGU2


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	209	213	PF00082	0.581
DOC_CDC14_PxL_1	76	84	PF14671	0.411
DOC_MAPK_gen_1	103	110	PF00069	0.538
DOC_MAPK_MEF2A_6	103	110	PF00069	0.538
DOC_PP1_RVXF_1	86	93	PF00149	0.458
DOC_PP2B_LxvP_1	27	30	PF13499	0.482
DOC_PP4_FxxP_1	92	95	PF00568	0.539
DOC_USP7_MATH_1	10	14	PF00917	0.599
DOC_USP7_MATH_1	66	70	PF00917	0.456
DOC_WW_Pin1_4	45	50	PF00397	0.564
LIG_APCC_ABBA_1	172	177	PF00400	0.471
LIG_APCC_ABBAyCdc20_2	171	177	PF00400	0.456
LIG_BIR_III_4	132	136	PF00653	0.395
LIG_BRCT_BRCA1_1	152	156	PF00533	0.538
LIG_FHA_1	165	171	PF00498	0.450
LIG_FHA_1	187	193	PF00498	0.528
LIG_FHA_2	46	52	PF00498	0.465
LIG_LIR_Apic_2	91	95	PF02991	0.589
LIG_Pex14_2	158	162	PF04695	0.440
MOD_CK1_1	149	155	PF00069	0.473
MOD_CK1_1	45	51	PF00069	0.517
MOD_CK2_1	207	213	PF00069	0.581
MOD_CK2_1	45	51	PF00069	0.461
MOD_GlcNHglycan	36	40	PF01048	0.333
MOD_GlcNHglycan	60	63	PF01048	0.350
MOD_GlcNHglycan	77	80	PF01048	0.348
MOD_GSK3_1	146	153	PF00069	0.499
MOD_GSK3_1	176	183	PF00069	0.633
MOD_GSK3_1	6	13	PF00069	0.567
MOD_N-GLC_1	96	101	PF02516	0.289
MOD_NEK2_1	158	163	PF00069	0.464
MOD_NEK2_1	42	47	PF00069	0.528
MOD_NEK2_1	56	61	PF00069	0.528
MOD_NEK2_1	75	80	PF00069	0.508
MOD_PIKK_1	180	186	PF00454	0.508
MOD_PK_1	147	153	PF00069	0.458
MOD_PKA_2	202	208	PF00069	0.483
MOD_Plk_1	158	164	PF00069	0.457
MOD_Plk_1	35	41	PF00069	0.465
MOD_Plk_2-3	207	213	PF00069	0.509
MOD_Plk_4	152	158	PF00069	0.499
MOD_Plk_4	207	213	PF00069	0.647
MOD_Plk_4	88	94	PF00069	0.524
MOD_ProDKin_1	45	51	PF00069	0.564
MOD_SUMO_rev_2	201	211	PF00179	0.598
TRG_DiLeu_BaLyEn_6	77	82	PF01217	0.411
TRG_Pf-PMV_PEXEL_1	209	213	PF00026	0.601


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5T0	Leptomonas seymouri	73%	100%
A0A0S4KLB0	Bodo saltans	42%	98%
A0A1X0NNQ9	Trypanosomatidae	49%	100%
A0A3S7WRT2	Leishmania donovani	94%	100%
A0A422N6F9	Trypanosoma rangeli	53%	100%
A4H6R6	Leishmania braziliensis	84%	100%
A4HV46	Leishmania infantum	94%	75%
C9ZQE0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9ANS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q6DJI5	Xenopus laevis	28%	100%
Q8BWR2	Mus musculus	27%	100%
Q9GZP4	Homo sapiens	27%	100%
Q9VK68	Drosophila melanogaster	30%	100%