Mitochondrial 28S ribosomal protein S29

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Mitochondrial SSU ribosomal protein 29, putative

Species:

Leishmania major

UniProt:

Q4QGU0_LEIMA

TriTrypDb:

LmjF.12.0040 , LMJLV39_120005400 , LMJSD75_120006200

Length:

467

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0000314	organellar small ribosomal subunit	5	2
GO:0005737	cytoplasm	2	2
GO:0005763	mitochondrial small ribosomal subunit	3	2
GO:0015935	small ribosomal subunit	4	2
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0032991	protein-containing complex	1	12
GO:0043233	organelle lumen	3	2
GO:0044391	ribosomal subunit	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0097014	ciliary plasm	5	2
GO:0098798	mitochondrial protein-containing complex	2	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	12
GO:1990904	ribonucleoprotein complex	2	12
GO:0005739	mitochondrion	5	10
GO:0005840	ribosome	5	10
GO:0043226	organelle	2	10
GO:0043227	membrane-bounded organelle	3	10
GO:0043228	non-membrane-bounded organelle	3	10
GO:0043229	intracellular organelle	3	10
GO:0043231	intracellular membrane-bounded organelle	4	10
GO:0043232	intracellular non-membrane-bounded organelle	4	10

Expansion

Sequence features

Q4QGU0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGU0

PDB structure(s): 7ane_r

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	2
GO:0005198	structural molecule activity	1	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.328
CLV_C14_Caspase3-7	279	283	PF00656	0.518
CLV_NRD_NRD_1	407	409	PF00675	0.379
CLV_NRD_NRD_1	450	452	PF00675	0.454
CLV_NRD_NRD_1	80	82	PF00675	0.391
CLV_PCSK_KEX2_1	439	441	PF00082	0.451
CLV_PCSK_KEX2_1	450	452	PF00082	0.420
CLV_PCSK_PC1ET2_1	439	441	PF00082	0.463
CLV_PCSK_PC7_1	435	441	PF00082	0.495
CLV_PCSK_SKI1_1	105	109	PF00082	0.453
CLV_PCSK_SKI1_1	124	128	PF00082	0.164
CLV_PCSK_SKI1_1	174	178	PF00082	0.328
CLV_PCSK_SKI1_1	21	25	PF00082	0.526
CLV_PCSK_SKI1_1	236	240	PF00082	0.413
CLV_PCSK_SKI1_1	275	279	PF00082	0.575
CLV_PCSK_SKI1_1	310	314	PF00082	0.389
CLV_PCSK_SKI1_1	328	332	PF00082	0.259
CLV_PCSK_SKI1_1	379	383	PF00082	0.406
CLV_PCSK_SKI1_1	76	80	PF00082	0.370
CLV_Separin_Metazoa	293	297	PF03568	0.408
DEG_APCC_DBOX_1	173	181	PF00400	0.475
DEG_Nend_Nbox_1	1	3	PF02207	0.441
DOC_AGCK_PIF_2	373	378	PF00069	0.394
DOC_CYCLIN_yCln2_LP_2	69	72	PF00134	0.482
DOC_MAPK_FxFP_2	266	269	PF00069	0.328
DOC_MAPK_gen_1	136	145	PF00069	0.315
DOC_MAPK_gen_1	243	252	PF00069	0.355
DOC_MAPK_gen_1	408	415	PF00069	0.388
DOC_MAPK_MEF2A_6	136	145	PF00069	0.330
DOC_MAPK_MEF2A_6	230	237	PF00069	0.341
DOC_MAPK_MEF2A_6	246	254	PF00069	0.284
DOC_MAPK_NFAT4_5	138	146	PF00069	0.363
DOC_PP1_RVXF_1	299	305	PF00149	0.379
DOC_PP1_RVXF_1	410	416	PF00149	0.395
DOC_PP2B_LxvP_1	69	72	PF13499	0.482
DOC_PP4_FxxP_1	167	170	PF00568	0.328
DOC_PP4_FxxP_1	266	269	PF00568	0.328
DOC_PP4_FxxP_1	364	367	PF00568	0.487
DOC_SPAK_OSR1_1	383	387	PF12202	0.353
DOC_USP7_MATH_1	103	107	PF00917	0.549
DOC_USP7_MATH_1	183	187	PF00917	0.355
DOC_USP7_MATH_1	385	389	PF00917	0.412
DOC_USP7_MATH_1	457	461	PF00917	0.668
DOC_WW_Pin1_4	193	198	PF00397	0.328
LIG_14-3-3_CanoR_1	230	234	PF00244	0.328
LIG_14-3-3_CanoR_1	275	281	PF00244	0.457
LIG_14-3-3_CanoR_1	301	305	PF00244	0.372
LIG_14-3-3_CanoR_1	346	352	PF00244	0.484
LIG_14-3-3_CanoR_1	81	90	PF00244	0.477
LIG_BRCT_BRCA1_1	402	406	PF00533	0.372
LIG_deltaCOP1_diTrp_1	155	158	PF00928	0.336
LIG_deltaCOP1_diTrp_1	255	260	PF00928	0.344
LIG_FHA_1	140	146	PF00498	0.338
LIG_FHA_1	18	24	PF00498	0.553
LIG_FHA_1	245	251	PF00498	0.449
LIG_FHA_2	150	156	PF00498	0.328
LIG_FHA_2	177	183	PF00498	0.421
LIG_FHA_2	194	200	PF00498	0.201
LIG_FHA_2	277	283	PF00498	0.479
LIG_FHA_2	324	330	PF00498	0.367
LIG_FHA_2	372	378	PF00498	0.525
LIG_Integrin_isoDGR_2	109	111	PF01839	0.540
LIG_LIR_Apic_2	155	159	PF02991	0.328
LIG_LIR_Apic_2	26	30	PF02991	0.451
LIG_LIR_Apic_2	263	269	PF02991	0.315
LIG_LIR_Apic_2	362	367	PF02991	0.487
LIG_LIR_Gen_1	255	263	PF02991	0.344
LIG_LIR_Gen_1	337	347	PF02991	0.562
LIG_LIR_Gen_1	39	47	PF02991	0.409
LIG_LIR_Nem_3	255	260	PF02991	0.334
LIG_LIR_Nem_3	327	333	PF02991	0.381
LIG_LIR_Nem_3	337	342	PF02991	0.426
LIG_LIR_Nem_3	352	357	PF02991	0.394
LIG_LIR_Nem_3	371	376	PF02991	0.447
LIG_LIR_Nem_3	377	381	PF02991	0.333
LIG_LIR_Nem_3	39	43	PF02991	0.429
LIG_PCNA_yPIPBox_3	51	65	PF02747	0.405
LIG_Pex14_1	434	438	PF04695	0.413
LIG_PTB_Apo_2	341	348	PF02174	0.558
LIG_SH2_NCK_1	27	31	PF00017	0.447
LIG_SH2_STAP1	376	380	PF00017	0.433
LIG_SH2_STAP1	402	406	PF00017	0.492
LIG_SH2_STAT3	80	83	PF00017	0.495
LIG_SH2_STAT5	144	147	PF00017	0.326
LIG_SH2_STAT5	446	449	PF00017	0.440
LIG_SH2_STAT5	47	50	PF00017	0.347
LIG_SH2_STAT5	57	60	PF00017	0.368
LIG_SH3_2	356	361	PF14604	0.496
LIG_SH3_3	292	298	PF00018	0.410
LIG_SH3_3	353	359	PF00018	0.473
LIG_SH3_3	456	462	PF00018	0.587
LIG_SH3_3	69	75	PF00018	0.417
LIG_SUMO_SIM_par_1	250	255	PF11976	0.348
LIG_WRPW_2	330	333	PF00400	0.400
MOD_CK1_1	261	267	PF00069	0.344
MOD_CK1_1	300	306	PF00069	0.385
MOD_CK2_1	149	155	PF00069	0.325
MOD_CK2_1	176	182	PF00069	0.449
MOD_CK2_1	347	353	PF00069	0.439
MOD_CK2_1	371	377	PF00069	0.511
MOD_CK2_1	401	407	PF00069	0.379
MOD_GlcNHglycan	124	127	PF01048	0.343
MOD_GlcNHglycan	336	339	PF01048	0.464
MOD_GlcNHglycan	387	390	PF01048	0.344
MOD_N-GLC_1	183	188	PF02516	0.364
MOD_N-GLC_1	36	41	PF02516	0.549
MOD_N-GLC_1	371	376	PF02516	0.520
MOD_NEK2_1	176	181	PF00069	0.432
MOD_NEK2_1	273	278	PF00069	0.465
MOD_NEK2_1	311	316	PF00069	0.453
MOD_NEK2_1	321	326	PF00069	0.280
MOD_PKA_1	81	87	PF00069	0.454
MOD_PKA_2	229	235	PF00069	0.328
MOD_PKA_2	300	306	PF00069	0.385
MOD_Plk_1	36	42	PF00069	0.543
MOD_Plk_2-3	282	288	PF00069	0.444
MOD_Plk_2-3	371	377	PF00069	0.511
MOD_Plk_4	158	164	PF00069	0.480
MOD_Plk_4	183	189	PF00069	0.322
MOD_Plk_4	300	306	PF00069	0.404
MOD_Plk_4	360	366	PF00069	0.430
MOD_Plk_4	42	48	PF00069	0.368
MOD_ProDKin_1	193	199	PF00069	0.328
MOD_SUMO_for_1	8	11	PF00179	0.545
MOD_SUMO_rev_2	403	410	PF00179	0.366
MOD_SUMO_rev_2	431	441	PF00179	0.493
TRG_DiLeu_BaEn_2	376	382	PF01217	0.425
TRG_ENDOCYTIC_2	378	381	PF00928	0.420
TRG_Pf-PMV_PEXEL_1	210	214	PF00026	0.434

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5D9	Leptomonas seymouri	89%	94%
A0A0S4KHM8	Bodo saltans	66%	93%
A0A1X0NMI2	Trypanosomatidae	76%	94%
A0A3R7K3G1	Trypanosoma rangeli	76%	93%
A0A3S7WRW9	Leishmania donovani	98%	100%
A4H6R8	Leishmania braziliensis	94%	94%
A4HV48	Leishmania infantum	98%	94%
C9ZQD8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	94%
E9ANS9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
V5DE49	Trypanosoma cruzi	76%	93%