Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

Q4QGQ2_LEIMA

TriTrypDb:

LmjF.12.0405 , LMJLV39_120009500 , LMJSD75_120009300

Length:

410

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGQ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGQ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	216	220	PF00656	0.585
CLV_C14_Caspase3-7	48	52	PF00656	0.621
CLV_NRD_NRD_1	101	103	PF00675	0.622
CLV_PCSK_SKI1_1	184	188	PF00082	0.683
CLV_PCSK_SKI1_1	296	300	PF00082	0.700
DEG_Nend_Nbox_1	1	3	PF02207	0.645
DEG_ODPH_VHL_1	176	188	PF01847	0.638
DEG_SCF_FBW7_1	300	307	PF00400	0.576
DEG_SCF_FBW7_1	396	402	PF00400	0.629
DEG_SCF_FBW7_2	348	355	PF00400	0.652
DEG_SPOP_SBC_1	16	20	PF00917	0.646
DOC_CKS1_1	301	306	PF01111	0.606
DOC_CKS1_1	396	401	PF01111	0.674
DOC_CYCLIN_yCln2_LP_2	388	394	PF00134	0.668
DOC_PP1_RVXF_1	236	243	PF00149	0.609
DOC_PP2B_LxvP_1	175	178	PF13499	0.559
DOC_PP4_FxxP_1	106	109	PF00568	0.632
DOC_USP7_MATH_1	143	147	PF00917	0.646
DOC_USP7_MATH_1	16	20	PF00917	0.742
DOC_USP7_MATH_1	266	270	PF00917	0.712
DOC_USP7_MATH_1	381	385	PF00917	0.636
DOC_WW_Pin1_4	107	112	PF00397	0.643
DOC_WW_Pin1_4	129	134	PF00397	0.659
DOC_WW_Pin1_4	155	160	PF00397	0.666
DOC_WW_Pin1_4	197	202	PF00397	0.709
DOC_WW_Pin1_4	250	255	PF00397	0.761
DOC_WW_Pin1_4	300	305	PF00397	0.691
DOC_WW_Pin1_4	322	327	PF00397	0.549
DOC_WW_Pin1_4	348	353	PF00397	0.725
DOC_WW_Pin1_4	382	387	PF00397	0.778
DOC_WW_Pin1_4	395	400	PF00397	0.651
LIG_14-3-3_CanoR_1	197	201	PF00244	0.721
LIG_14-3-3_CanoR_1	72	81	PF00244	0.603
LIG_AP_GAE_1	93	99	PF02883	0.578
LIG_BIR_III_2	282	286	PF00653	0.667
LIG_BIR_III_4	51	55	PF00653	0.603
LIG_BRCT_BRCA1_1	324	328	PF00533	0.675
LIG_Clathr_ClatBox_1	8	12	PF01394	0.605
LIG_FHA_1	152	158	PF00498	0.686
LIG_FHA_1	305	311	PF00498	0.645
LIG_FHA_1	387	393	PF00498	0.667
LIG_FHA_2	177	183	PF00498	0.540
LIG_FHA_2	214	220	PF00498	0.574
LIG_FHA_2	368	374	PF00498	0.672
LIG_FHA_2	46	52	PF00498	0.593
LIG_IRF3_LxIS_1	56	63	PF10401	0.622
LIG_LIR_Apic_2	105	109	PF02991	0.632
LIG_LIR_Gen_1	93	104	PF02991	0.637
LIG_LIR_Nem_3	93	99	PF02991	0.650
LIG_NRBOX	4	10	PF00104	0.584
LIG_RPA_C_Fungi	67	79	PF08784	0.581
LIG_SH2_GRB2like	150	153	PF00017	0.632
LIG_SH2_STAT5	361	364	PF00017	0.625
LIG_SH3_3	130	136	PF00018	0.632
LIG_SH3_3	161	167	PF00018	0.607
LIG_SH3_3	227	233	PF00018	0.748
LIG_SH3_3	302	308	PF00018	0.735
LIG_SH3_3	318	324	PF00018	0.530
LIG_SUMO_SIM_anti_2	181	190	PF11976	0.633
LIG_SUMO_SIM_par_1	153	158	PF11976	0.641
LIG_SUMO_SIM_par_1	181	190	PF11976	0.644
LIG_SUMO_SIM_par_1	6	12	PF11976	0.597
LIG_TRAF2_1	111	114	PF00917	0.536
LIG_TRAF2_1	352	355	PF00917	0.649
LIG_WW_3	79	83	PF00397	0.626
MOD_CDC14_SPxK_1	200	203	PF00782	0.715
MOD_CDK_SPxK_1	197	203	PF00069	0.712
MOD_CK1_1	124	130	PF00069	0.590
MOD_CK1_1	135	141	PF00069	0.615
MOD_CK1_1	18	24	PF00069	0.713
MOD_CK1_1	199	205	PF00069	0.672
MOD_CK1_1	26	32	PF00069	0.655
MOD_CK2_1	122	128	PF00069	0.632
MOD_CK2_1	70	76	PF00069	0.759
MOD_GlcNHglycan	168	171	PF01048	0.651
MOD_GlcNHglycan	194	197	PF01048	0.632
MOD_GlcNHglycan	219	223	PF01048	0.720
MOD_GlcNHglycan	258	261	PF01048	0.731
MOD_GlcNHglycan	268	271	PF01048	0.723
MOD_GlcNHglycan	28	31	PF01048	0.647
MOD_GlcNHglycan	355	359	PF01048	0.646
MOD_GlcNHglycan	72	75	PF01048	0.661
MOD_GlcNHglycan	87	90	PF01048	0.592
MOD_GSK3_1	15	22	PF00069	0.744
MOD_GSK3_1	151	158	PF00069	0.655
MOD_GSK3_1	192	199	PF00069	0.723
MOD_GSK3_1	24	31	PF00069	0.720
MOD_GSK3_1	300	307	PF00069	0.702
MOD_GSK3_1	382	389	PF00069	0.741
MOD_GSK3_1	395	402	PF00069	0.666
MOD_GSK3_1	66	73	PF00069	0.692
MOD_N-GLC_1	151	156	PF02516	0.612
MOD_N-GLC_1	44	49	PF02516	0.505
MOD_NEK2_1	121	126	PF00069	0.674
MOD_NEK2_1	299	304	PF00069	0.699
MOD_NEK2_1	328	333	PF00069	0.655
MOD_NEK2_1	60	65	PF00069	0.639
MOD_NEK2_1	70	75	PF00069	0.572
MOD_NEK2_1	92	97	PF00069	0.576
MOD_PIKK_1	231	237	PF00454	0.651
MOD_PKA_2	196	202	PF00069	0.700
MOD_Plk_1	151	157	PF00069	0.615
MOD_Plk_1	44	50	PF00069	0.503
MOD_Plk_1	92	98	PF00069	0.601
MOD_Plk_4	171	177	PF00069	0.583
MOD_Plk_4	3	9	PF00069	0.553
MOD_ProDKin_1	107	113	PF00069	0.645
MOD_ProDKin_1	129	135	PF00069	0.657
MOD_ProDKin_1	155	161	PF00069	0.691
MOD_ProDKin_1	197	203	PF00069	0.712
MOD_ProDKin_1	250	256	PF00069	0.763
MOD_ProDKin_1	300	306	PF00069	0.691
MOD_ProDKin_1	322	328	PF00069	0.552
MOD_ProDKin_1	348	354	PF00069	0.726
MOD_ProDKin_1	382	388	PF00069	0.781
MOD_ProDKin_1	395	401	PF00069	0.650
TRG_DiLeu_BaEn_1	181	186	PF01217	0.679
TRG_DiLeu_LyEn_5	181	186	PF01217	0.679
TRG_ER_diArg_1	236	239	PF00400	0.590
TRG_NES_CRM1_1	364	376	PF08389	0.526
TRG_Pf-PMV_PEXEL_1	238	243	PF00026	0.610
TRG_Pf-PMV_PEXEL_1	90	94	PF00026	0.590

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H6K7	Leishmania donovani	89%	100%
A4H6V6	Leishmania braziliensis	58%	100%
E9AGC8	Leishmania infantum	89%	100%
E9ANW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%