Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Bromodomain factor 6, putative

Species:

Leishmania major

UniProt:

Q4QGP9_LEIMA

TriTrypDb:

LmjF.12.0430 , LMJLV39_120009800 , LMJSD75_120009600

Length:

669

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGP9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGP9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	256	260	PF00656	0.687
CLV_C14_Caspase3-7	601	605	PF00656	0.675
CLV_NRD_NRD_1	503	505	PF00675	0.547
CLV_NRD_NRD_1	585	587	PF00675	0.704
CLV_NRD_NRD_1	611	613	PF00675	0.599
CLV_PCSK_KEX2_1	503	505	PF00082	0.530
CLV_PCSK_KEX2_1	585	587	PF00082	0.719
CLV_PCSK_KEX2_1	611	613	PF00082	0.572
CLV_PCSK_SKI1_1	176	180	PF00082	0.659
CLV_PCSK_SKI1_1	443	447	PF00082	0.629
CLV_PCSK_SKI1_1	536	540	PF00082	0.693
CLV_PCSK_SKI1_1	600	604	PF00082	0.680
CLV_PCSK_SKI1_1	611	615	PF00082	0.443
DEG_APCC_DBOX_1	435	443	PF00400	0.625
DEG_Kelch_Keap1_1	241	246	PF01344	0.618
DEG_Nend_Nbox_1	1	3	PF02207	0.559
DEG_SPOP_SBC_1	213	217	PF00917	0.733
DEG_SPOP_SBC_1	551	555	PF00917	0.624
DOC_CKS1_1	182	187	PF01111	0.790
DOC_CKS1_1	444	449	PF01111	0.620
DOC_CKS1_1	539	544	PF01111	0.693
DOC_CYCLIN_RxL_1	533	543	PF00134	0.683
DOC_CYCLIN_yCln2_LP_2	182	188	PF00134	0.792
DOC_CYCLIN_yCln2_LP_2	419	425	PF00134	0.512
DOC_MAPK_gen_1	332	339	PF00069	0.780
DOC_PP2B_LxvP_1	264	267	PF13499	0.671
DOC_PP4_FxxP_1	469	472	PF00568	0.610
DOC_PP4_FxxP_1	568	571	PF00568	0.654
DOC_PP4_FxxP_1	633	636	PF00568	0.611
DOC_USP7_MATH_1	18	22	PF00917	0.669
DOC_USP7_MATH_1	207	211	PF00917	0.614
DOC_USP7_MATH_1	214	218	PF00917	0.692
DOC_USP7_MATH_1	235	239	PF00917	0.727
DOC_USP7_MATH_1	252	256	PF00917	0.782
DOC_USP7_MATH_1	280	284	PF00917	0.688
DOC_USP7_MATH_1	288	292	PF00917	0.699
DOC_USP7_MATH_1	314	318	PF00917	0.643
DOC_USP7_MATH_1	380	384	PF00917	0.813
DOC_USP7_MATH_1	50	54	PF00917	0.580
DOC_USP7_MATH_1	551	555	PF00917	0.780
DOC_USP7_MATH_1	594	598	PF00917	0.664
DOC_USP7_MATH_1	606	610	PF00917	0.504
DOC_USP7_MATH_1	71	75	PF00917	0.726
DOC_USP7_MATH_1	84	88	PF00917	0.654
DOC_WW_Pin1_4	181	186	PF00397	0.788
DOC_WW_Pin1_4	284	289	PF00397	0.841
DOC_WW_Pin1_4	323	328	PF00397	0.788
DOC_WW_Pin1_4	409	414	PF00397	0.687
DOC_WW_Pin1_4	418	423	PF00397	0.466
DOC_WW_Pin1_4	429	434	PF00397	0.399
DOC_WW_Pin1_4	443	448	PF00397	0.441
DOC_WW_Pin1_4	468	473	PF00397	0.609
DOC_WW_Pin1_4	492	497	PF00397	0.454
DOC_WW_Pin1_4	538	543	PF00397	0.729
DOC_WW_Pin1_4	80	85	PF00397	0.778
LIG_14-3-3_CanoR_1	176	181	PF00244	0.668
LIG_14-3-3_CanoR_1	198	208	PF00244	0.589
LIG_14-3-3_CanoR_1	225	235	PF00244	0.757
LIG_14-3-3_CanoR_1	347	357	PF00244	0.825
LIG_14-3-3_CanoR_1	494	500	PF00244	0.484
LIG_14-3-3_CanoR_1	503	513	PF00244	0.429
LIG_14-3-3_CanoR_1	515	521	PF00244	0.569
LIG_14-3-3_CanoR_1	55	61	PF00244	0.595
LIG_14-3-3_CanoR_1	611	617	PF00244	0.597
LIG_14-3-3_CanoR_1	639	647	PF00244	0.613
LIG_BIR_III_4	6	10	PF00653	0.581
LIG_BRCT_BRCA1_1	32	36	PF00533	0.556
LIG_CtBP_PxDLS_1	496	500	PF00389	0.600
LIG_deltaCOP1_diTrp_1	104	111	PF00928	0.680
LIG_deltaCOP1_diTrp_1	420	427	PF00928	0.645
LIG_EVH1_2	410	414	PF00568	0.719
LIG_FHA_1	120	126	PF00498	0.686
LIG_FHA_1	177	183	PF00498	0.682
LIG_FHA_1	200	206	PF00498	0.797
LIG_FHA_1	227	233	PF00498	0.744
LIG_FHA_1	36	42	PF00498	0.553
LIG_FHA_1	87	93	PF00498	0.812
LIG_FHA_2	254	260	PF00498	0.763
LIG_FHA_2	295	301	PF00498	0.782
LIG_FHA_2	35	41	PF00498	0.770
LIG_FHA_2	475	481	PF00498	0.629
LIG_FHA_2	575	581	PF00498	0.669
LIG_FHA_2	613	619	PF00498	0.582
LIG_LIR_Apic_2	467	472	PF02991	0.611
LIG_LIR_Apic_2	566	571	PF02991	0.578
LIG_LIR_Gen_1	108	119	PF02991	0.643
LIG_LIR_Gen_1	29	36	PF02991	0.555
LIG_LIR_Gen_1	451	461	PF02991	0.589
LIG_LIR_Gen_1	486	497	PF02991	0.629
LIG_LIR_Nem_3	104	109	PF02991	0.694
LIG_LIR_Nem_3	110	114	PF02991	0.538
LIG_LIR_Nem_3	29	34	PF02991	0.610
LIG_LIR_Nem_3	420	426	PF02991	0.510
LIG_LIR_Nem_3	451	456	PF02991	0.591
LIG_LIR_Nem_3	458	463	PF02991	0.482
LIG_LIR_Nem_3	480	484	PF02991	0.667
LIG_LIR_Nem_3	486	492	PF02991	0.529
LIG_LIR_Nem_3	580	584	PF02991	0.828
LIG_PDZ_Class_2	664	669	PF00595	0.680
LIG_SH2_CRK	13	17	PF00017	0.616
LIG_SH2_CRK	444	448	PF00017	0.622
LIG_SH2_CRK	489	493	PF00017	0.624
LIG_SH2_CRK	581	585	PF00017	0.833
LIG_SH2_NCK_1	513	517	PF00017	0.613
LIG_SH2_STAP1	13	17	PF00017	0.616
LIG_SH2_STAP1	166	170	PF00017	0.621
LIG_SH2_STAP1	513	517	PF00017	0.652
LIG_SH2_STAT5	424	427	PF00017	0.402
LIG_SH2_STAT5	505	508	PF00017	0.606
LIG_SH2_STAT5	658	661	PF00017	0.593
LIG_SH3_3	248	254	PF00018	0.854
LIG_SH3_3	279	285	PF00018	0.833
LIG_SH3_3	407	413	PF00018	0.743
LIG_SH3_3	490	496	PF00018	0.645
LIG_SH3_3	568	574	PF00018	0.609
LIG_SUMO_SIM_par_1	446	452	PF11976	0.378
LIG_SUMO_SIM_par_1	495	501	PF11976	0.607
LIG_SUMO_SIM_par_1	612	618	PF11976	0.589
LIG_TYR_ITIM	11	16	PF00017	0.596
LIG_WRC_WIRS_1	663	668	PF05994	0.571
MOD_CDK_SPxxK_3	429	436	PF00069	0.562
MOD_CK1_1	255	261	PF00069	0.752
MOD_CK1_1	29	35	PF00069	0.554
MOD_CK1_1	317	323	PF00069	0.640
MOD_CK1_1	326	332	PF00069	0.661
MOD_CK1_1	387	393	PF00069	0.655
MOD_CK1_1	429	435	PF00069	0.642
MOD_CK1_1	495	501	PF00069	0.429
MOD_CK1_1	566	572	PF00069	0.784
MOD_CK1_1	605	611	PF00069	0.701
MOD_CK2_1	18	24	PF00069	0.621
MOD_CK2_1	240	246	PF00069	0.617
MOD_CK2_1	294	300	PF00069	0.658
MOD_CK2_1	409	415	PF00069	0.718
MOD_CK2_1	452	458	PF00069	0.583
MOD_CK2_1	474	480	PF00069	0.631
MOD_CK2_1	495	501	PF00069	0.607
MOD_CK2_1	551	557	PF00069	0.666
MOD_CK2_1	574	580	PF00069	0.693
MOD_CK2_1	612	618	PF00069	0.589
MOD_CK2_1	96	102	PF00069	0.700
MOD_DYRK1A_RPxSP_1	409	413	PF00069	0.582
MOD_GlcNHglycan	126	129	PF01048	0.548
MOD_GlcNHglycan	243	246	PF01048	0.807
MOD_GlcNHglycan	247	250	PF01048	0.785
MOD_GlcNHglycan	259	262	PF01048	0.694
MOD_GlcNHglycan	290	293	PF01048	0.722
MOD_GlcNHglycan	312	315	PF01048	0.830
MOD_GlcNHglycan	381	385	PF01048	0.807
MOD_GlcNHglycan	386	389	PF01048	0.726
MOD_GlcNHglycan	485	488	PF01048	0.631
MOD_GlcNHglycan	547	550	PF01048	0.792
MOD_GlcNHglycan	565	568	PF01048	0.517
MOD_GlcNHglycan	590	593	PF01048	0.654
MOD_GlcNHglycan	604	607	PF01048	0.483
MOD_GlcNHglycan	66	69	PF01048	0.725
MOD_GlcNHglycan	73	76	PF01048	0.617
MOD_GSK3_1	208	215	PF00069	0.612
MOD_GSK3_1	235	242	PF00069	0.841
MOD_GSK3_1	253	260	PF00069	0.678
MOD_GSK3_1	26	33	PF00069	0.709
MOD_GSK3_1	280	287	PF00069	0.673
MOD_GSK3_1	294	301	PF00069	0.679
MOD_GSK3_1	310	317	PF00069	0.824
MOD_GSK3_1	322	329	PF00069	0.677
MOD_GSK3_1	360	367	PF00069	0.687
MOD_GSK3_1	380	387	PF00069	0.562
MOD_GSK3_1	399	406	PF00069	0.513
MOD_GSK3_1	488	495	PF00069	0.494
MOD_GSK3_1	50	57	PF00069	0.581
MOD_GSK3_1	541	548	PF00069	0.769
MOD_GSK3_1	551	558	PF00069	0.677
MOD_GSK3_1	569	576	PF00069	0.509
MOD_GSK3_1	594	601	PF00069	0.672
MOD_GSK3_1	602	609	PF00069	0.593
MOD_GSK3_1	71	78	PF00069	0.745
MOD_GSK3_1	80	87	PF00069	0.764
MOD_LATS_1	362	368	PF00433	0.732
MOD_N-GLC_1	240	245	PF02516	0.732
MOD_NEK2_1	199	204	PF00069	0.763
MOD_NEK2_1	239	244	PF00069	0.773
MOD_NEK2_1	391	396	PF00069	0.711
MOD_NEK2_1	426	431	PF00069	0.490
MOD_NEK2_1	550	555	PF00069	0.810
MOD_NEK2_1	556	561	PF00069	0.709
MOD_NEK2_1	602	607	PF00069	0.721
MOD_NEK2_1	619	624	PF00069	0.300
MOD_NEK2_2	516	521	PF00069	0.590
MOD_PIKK_1	265	271	PF00454	0.644
MOD_PIKK_1	327	333	PF00454	0.652
MOD_PK_1	364	370	PF00069	0.736
MOD_PKA_1	44	50	PF00069	0.817
MOD_PKA_2	26	32	PF00069	0.584
MOD_PKA_2	54	60	PF00069	0.704
MOD_Plk_1	109	115	PF00069	0.631
MOD_Plk_1	208	214	PF00069	0.609
MOD_Plk_1	399	405	PF00069	0.718
MOD_Plk_1	451	457	PF00069	0.586
MOD_Plk_1	619	625	PF00069	0.581
MOD_Plk_2-3	452	458	PF00069	0.583
MOD_Plk_2-3	598	604	PF00069	0.658
MOD_Plk_4	26	32	PF00069	0.607
MOD_Plk_4	260	266	PF00069	0.611
MOD_Plk_4	399	405	PF00069	0.659
MOD_Plk_4	452	458	PF00069	0.583
MOD_Plk_4	474	480	PF00069	0.631
MOD_Plk_4	488	494	PF00069	0.403
MOD_Plk_4	662	668	PF00069	0.564
MOD_ProDKin_1	181	187	PF00069	0.790
MOD_ProDKin_1	284	290	PF00069	0.835
MOD_ProDKin_1	323	329	PF00069	0.788
MOD_ProDKin_1	409	415	PF00069	0.676
MOD_ProDKin_1	418	424	PF00069	0.461
MOD_ProDKin_1	429	435	PF00069	0.391
MOD_ProDKin_1	443	449	PF00069	0.440
MOD_ProDKin_1	468	474	PF00069	0.614
MOD_ProDKin_1	492	498	PF00069	0.446
MOD_ProDKin_1	538	544	PF00069	0.729
MOD_ProDKin_1	80	86	PF00069	0.777
MOD_SUMO_rev_2	67	74	PF00179	0.592
TRG_DiLeu_BaEn_1	458	463	PF01217	0.598
TRG_DiLeu_BaLyEn_6	534	539	PF01217	0.684
TRG_ENDOCYTIC_2	13	16	PF00928	0.607
TRG_ENDOCYTIC_2	489	492	PF00928	0.633
TRG_ENDOCYTIC_2	581	584	PF00928	0.833
TRG_ER_diArg_1	502	504	PF00400	0.529
TRG_ER_diArg_1	534	537	PF00400	0.792
TRG_ER_diArg_1	584	586	PF00400	0.822
TRG_ER_diArg_1	611	613	PF00400	0.613
TRG_Pf-PMV_PEXEL_1	504	508	PF00026	0.613
TRG_Pf-PMV_PEXEL_1	600	604	PF00026	0.662

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WRW8	Leishmania donovani	90%	100%
A4H6V8	Leishmania braziliensis	68%	100%
E9AGD1	Leishmania infantum	90%	100%
E9ANX1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%