Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QGP8_LEIMA

TriTrypDb:

LmjF.12.0440 , LMJLV39_120009900 , LMJSD75_120009700 , LMJSD75_120009800

Length:

710

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGP8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGP8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	266	270	PF00656	0.802
CLV_C14_Caspase3-7	322	326	PF00656	0.725
CLV_C14_Caspase3-7	390	394	PF00656	0.702
CLV_C14_Caspase3-7	423	427	PF00656	0.742
CLV_C14_Caspase3-7	543	547	PF00656	0.515
CLV_NRD_NRD_1	138	140	PF00675	0.548
CLV_NRD_NRD_1	141	143	PF00675	0.563
CLV_NRD_NRD_1	334	336	PF00675	0.720
CLV_NRD_NRD_1	419	421	PF00675	0.625
CLV_NRD_NRD_1	464	466	PF00675	0.623

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2D5	Leptomonas seymouri	37%	100%
A0A3S7WRY8	Leishmania donovani	87%	100%
A4H6V9	Leishmania braziliensis	68%	98%
E9AGD2	Leishmania infantum	87%	100%
E9ANX2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%

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