Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QGP3_LEIMA

TriTrypDb:

LmjF.12.0490 , LMJLV39_120010500 , LMJSD75_120010400

Length:

303

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGP3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGP3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DEG_COP1_1	124	135	PF00400	0.555
DEG_SPOP_SBC_1	8	12	PF00917	0.603
DOC_PP2B_LxvP_1	15	18	PF13499	0.751
DOC_PP4_FxxP_1	60	63	PF00568	0.786
DOC_USP7_MATH_1	115	119	PF00917	0.793
DOC_USP7_MATH_1	141	145	PF00917	0.776
DOC_USP7_MATH_1	157	161	PF00917	0.571
DOC_USP7_MATH_1	18	22	PF00917	0.720
DOC_USP7_MATH_1	184	188	PF00917	0.741
DOC_USP7_MATH_1	233	237	PF00917	0.582
DOC_USP7_MATH_2	151	157	PF00917	0.792
DOC_WW_Pin1_4	137	142	PF00397	0.775
DOC_WW_Pin1_4	212	217	PF00397	0.785
LIG_BIR_II_1	1	5	PF00653	0.615
LIG_deltaCOP1_diTrp_1	200	209	PF00928	0.732
LIG_FHA_1	122	128	PF00498	0.722
LIG_FHA_1	138	144	PF00498	0.569
LIG_FHA_2	123	129	PF00498	0.576
LIG_FHA_2	251	257	PF00498	0.691
LIG_LIR_Apic_2	46	51	PF02991	0.733
LIG_LIR_LC3C_4	28	32	PF02991	0.688
LIG_LIR_Nem_3	223	227	PF02991	0.773
LIG_Pex14_1	168	172	PF04695	0.733
LIG_SH2_CRK	48	52	PF00017	0.697
LIG_SH2_STAT5	48	51	PF00017	0.697
LIG_SH3_3	28	34	PF00018	0.733
LIG_SH3_3	78	84	PF00018	0.665
LIG_SUMO_SIM_anti_2	28	34	PF11976	0.685
LIG_TRAF2_1	216	219	PF00917	0.797
LIG_TRAF2_1	282	285	PF00917	0.753
MOD_CDK_SPK_2	212	217	PF00069	0.785
MOD_CK1_1	113	119	PF00069	0.799
MOD_CK1_1	2	8	PF00069	0.732
MOD_CK1_1	212	218	PF00069	0.787
MOD_CK1_1	46	52	PF00069	0.733
MOD_CK1_1	71	77	PF00069	0.761
MOD_CK2_1	1	7	PF00069	0.730
MOD_CK2_1	122	128	PF00069	0.576
MOD_CK2_1	212	218	PF00069	0.787
MOD_CK2_1	250	256	PF00069	0.663
MOD_CK2_1	58	64	PF00069	0.774
MOD_GlcNHglycan	117	120	PF01048	0.788
MOD_GlcNHglycan	155	158	PF01048	0.783
MOD_GlcNHglycan	173	176	PF01048	0.518
MOD_GlcNHglycan	190	193	PF01048	0.460
MOD_GlcNHglycan	20	23	PF01048	0.773
MOD_GlcNHglycan	210	214	PF01048	0.488
MOD_GlcNHglycan	236	239	PF01048	0.723
MOD_GlcNHglycan	280	283	PF01048	0.687
MOD_GlcNHglycan	71	74	PF01048	0.768
MOD_GlcNHglycan	99	102	PF01048	0.743
MOD_GSK3_1	110	117	PF00069	0.839
MOD_GSK3_1	131	138	PF00069	0.757
MOD_GSK3_1	149	156	PF00069	0.762
MOD_GSK3_1	173	180	PF00069	0.674
MOD_GSK3_1	184	191	PF00069	0.574
MOD_GSK3_1	2	9	PF00069	0.683
MOD_GSK3_1	205	212	PF00069	0.754
MOD_GSK3_1	39	46	PF00069	0.738
MOD_GSK3_1	93	100	PF00069	0.717
MOD_N-GLC_1	188	193	PF02516	0.671
MOD_N-GLC_1	69	74	PF02516	0.762
MOD_NEK2_1	1	6	PF00069	0.653
MOD_NEK2_1	135	140	PF00069	0.741
MOD_NEK2_1	209	214	PF00069	0.773
MOD_NEK2_1	93	98	PF00069	0.752
MOD_PIKK_1	173	179	PF00454	0.678
MOD_PIKK_1	270	276	PF00454	0.636
MOD_PIKK_1	43	49	PF00454	0.696
MOD_Plk_4	10	16	PF00069	0.724
MOD_Plk_4	143	149	PF00069	0.708
MOD_Plk_4	93	99	PF00069	0.705
MOD_ProDKin_1	137	143	PF00069	0.778
MOD_ProDKin_1	212	218	PF00069	0.787
MOD_SUMO_rev_2	74	84	PF00179	0.760
TRG_DiLeu_BaLyEn_6	54	59	PF01217	0.758
TRG_Pf-PMV_PEXEL_1	161	165	PF00026	0.743

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8I979	Leishmania donovani	91%	96%
A4H6W8	Leishmania braziliensis	65%	100%
E9AGD7	Leishmania infantum	92%	96%
E9ANX7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%