Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QGP2_LEIMA

TriTrypDb:

LmjF.12.0500 , LMJLV39_120010600 , LMJSD75_120010500

Length:

1036

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGP2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGP2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	134	138	PF00656	0.674
CLV_C14_Caspase3-7	428	432	PF00656	0.604
CLV_C14_Caspase3-7	603	607	PF00656	0.686
CLV_C14_Caspase3-7	952	956	PF00656	0.555
CLV_NRD_NRD_1	1014	1016	PF00675	0.700
CLV_NRD_NRD_1	180	182	PF00675	0.713
CLV_NRD_NRD_1	367	369	PF00675	0.757
CLV_NRD_NRD_1	390	392	PF00675	0.723
CLV_NRD_NRD_1	471	473	PF00675	0.728
CLV_NRD_NRD_1	496	498	PF00675	0.677
CLV_NRD_NRD_1	538	540	PF00675	0.673
CLV_NRD_NRD_1	67	69	PF00675	0.608
CLV_NRD_NRD_1	680	682	PF00675	0.761
CLV_NRD_NRD_1	701	703	PF00675	0.691
CLV_NRD_NRD_1	800	802	PF00675	0.584
CLV_NRD_NRD_1	839	841	PF00675	0.721
CLV_PCSK_FUR_1	798	802	PF00082	0.582
CLV_PCSK_KEX2_1	1014	1016	PF00082	0.700
CLV_PCSK_KEX2_1	180	182	PF00082	0.713
CLV_PCSK_KEX2_1	367	369	PF00082	0.685
CLV_PCSK_KEX2_1	470	472	PF00082	0.768
CLV_PCSK_KEX2_1	496	498	PF00082	0.677
CLV_PCSK_KEX2_1	519	521	PF00082	0.572
CLV_PCSK_KEX2_1	537	539	PF00082	0.612
CLV_PCSK_KEX2_1	700	702	PF00082	0.698
CLV_PCSK_KEX2_1	771	773	PF00082	0.568
CLV_PCSK_KEX2_1	800	802	PF00082	0.584
CLV_PCSK_KEX2_1	839	841	PF00082	0.721
CLV_PCSK_PC1ET2_1	519	521	PF00082	0.564
CLV_PCSK_PC1ET2_1	771	773	PF00082	0.568
CLV_PCSK_PC7_1	466	472	PF00082	0.727
CLV_PCSK_PC7_1	796	802	PF00082	0.577
CLV_PCSK_SKI1_1	180	184	PF00082	0.679
CLV_PCSK_SKI1_1	392	396	PF00082	0.600
CLV_PCSK_SKI1_1	513	517	PF00082	0.712
CLV_PCSK_SKI1_1	519	523	PF00082	0.628
CLV_PCSK_SKI1_1	645	649	PF00082	0.681
CLV_PCSK_SKI1_1	68	72	PF00082	0.643
DEG_APCC_DBOX_1	179	187	PF00400	0.674
DEG_APCC_DBOX_1	258	266	PF00400	0.643
DEG_SPOP_SBC_1	326	330	PF00917	0.654
DEG_SPOP_SBC_1	481	485	PF00917	0.748
DEG_SPOP_SBC_1	647	651	PF00917	0.691
DOC_CKS1_1	1	6	PF01111	0.634
DOC_CKS1_1	237	242	PF01111	0.701
DOC_CKS1_1	897	902	PF01111	0.588
DOC_CYCLIN_RxL_1	177	185	PF00134	0.676
DOC_CYCLIN_yCln2_LP_2	443	449	PF00134	0.658
DOC_CYCLIN_yCln2_LP_2	582	588	PF00134	0.612
DOC_MAPK_MEF2A_6	303	310	PF00069	0.627
DOC_MAPK_MEF2A_6	399	406	PF00069	0.672
DOC_MAPK_MEF2A_6	562	571	PF00069	0.668
DOC_MAPK_MEF2A_6	90	99	PF00069	0.601
DOC_MAPK_NFAT4_5	303	311	PF00069	0.628
DOC_PP2B_LxvP_1	422	425	PF13499	0.722
DOC_PP2B_LxvP_1	455	458	PF13499	0.658
DOC_PP2B_LxvP_1	582	585	PF13499	0.607
DOC_PP2B_LxvP_1	970	973	PF13499	0.653
DOC_PP4_FxxP_1	59	62	PF00568	0.623
DOC_PP4_FxxP_1	897	900	PF00568	0.560
DOC_PP4_MxPP_1	241	244	PF00568	0.692
DOC_USP7_MATH_1	117	121	PF00917	0.691
DOC_USP7_MATH_1	161	165	PF00917	0.697
DOC_USP7_MATH_1	197	201	PF00917	0.848
DOC_USP7_MATH_1	32	36	PF00917	0.722
DOC_USP7_MATH_1	326	330	PF00917	0.681
DOC_USP7_MATH_1	418	422	PF00917	0.657
DOC_USP7_MATH_1	553	557	PF00917	0.695
DOC_USP7_MATH_1	561	565	PF00917	0.761
DOC_USP7_MATH_1	600	604	PF00917	0.703
DOC_USP7_MATH_1	670	674	PF00917	0.575
DOC_USP7_MATH_1	851	855	PF00917	0.671
DOC_USP7_MATH_1	891	895	PF00917	0.641
DOC_USP7_MATH_1	920	924	PF00917	0.675
DOC_USP7_MATH_1	973	977	PF00917	0.615
DOC_USP7_MATH_2	409	415	PF00917	0.656
DOC_WW_Pin1_4	107	112	PF00397	0.693
DOC_WW_Pin1_4	118	123	PF00397	0.612
DOC_WW_Pin1_4	129	134	PF00397	0.614
DOC_WW_Pin1_4	144	149	PF00397	0.597
DOC_WW_Pin1_4	236	241	PF00397	0.666
DOC_WW_Pin1_4	248	253	PF00397	0.565
DOC_WW_Pin1_4	277	282	PF00397	0.646
DOC_WW_Pin1_4	329	334	PF00397	0.647
DOC_WW_Pin1_4	457	462	PF00397	0.679
DOC_WW_Pin1_4	548	553	PF00397	0.665
DOC_WW_Pin1_4	592	597	PF00397	0.836
DOC_WW_Pin1_4	755	760	PF00397	0.679
DOC_WW_Pin1_4	801	806	PF00397	0.596
DOC_WW_Pin1_4	860	865	PF00397	0.643
DOC_WW_Pin1_4	896	901	PF00397	0.595
DOC_WW_Pin1_4	909	914	PF00397	0.631
DOC_WW_Pin1_4	983	988	PF00397	0.701
LIG_14-3-3_CanoR_1	116	122	PF00244	0.681
LIG_14-3-3_CanoR_1	181	187	PF00244	0.568
LIG_14-3-3_CanoR_1	341	347	PF00244	0.684
LIG_14-3-3_CanoR_1	437	447	PF00244	0.670
LIG_14-3-3_CanoR_1	496	501	PF00244	0.669
LIG_14-3-3_CanoR_1	75	85	PF00244	0.636
LIG_14-3-3_CanoR_1	761	766	PF00244	0.583
LIG_14-3-3_CanoR_1	803	813	PF00244	0.580
LIG_APCC_ABBA_1	788	793	PF00400	0.671
LIG_APCC_ABBA_1	957	962	PF00400	0.654
LIG_BRCT_BRCA1_1	120	124	PF00533	0.710
LIG_BRCT_BRCA1_1	35	39	PF00533	0.630
LIG_BRCT_BRCA1_1	893	897	PF00533	0.574
LIG_FHA_1	130	136	PF00498	0.682
LIG_FHA_1	15	21	PF00498	0.558
LIG_FHA_1	209	215	PF00498	0.680
LIG_FHA_1	267	273	PF00498	0.652
LIG_FHA_1	330	336	PF00498	0.639
LIG_FHA_1	378	384	PF00498	0.679
LIG_FHA_1	438	444	PF00498	0.686
LIG_FHA_1	648	654	PF00498	0.709
LIG_FHA_1	778	784	PF00498	0.600
LIG_FHA_1	822	828	PF00498	0.659
LIG_FHA_1	871	877	PF00498	0.675
LIG_FHA_1	92	98	PF00498	0.593
LIG_FHA_2	125	131	PF00498	0.708
LIG_FHA_2	132	138	PF00498	0.649
LIG_FHA_2	426	432	PF00498	0.632
LIG_FHA_2	448	454	PF00498	0.539
LIG_FHA_2	620	626	PF00498	0.643
LIG_LIR_Apic_2	58	62	PF02991	0.622
LIG_LIR_Apic_2	894	900	PF02991	0.567
LIG_LIR_Gen_1	155	163	PF02991	0.656
LIG_LIR_Gen_1	636	647	PF02991	0.568
LIG_LIR_Nem_3	101	106	PF02991	0.506
LIG_LIR_Nem_3	155	159	PF02991	0.673
LIG_LIR_Nem_3	58	63	PF02991	0.618
LIG_LIR_Nem_3	636	642	PF02991	0.572
LIG_LIR_Nem_3	84	89	PF02991	0.605
LIG_MYND_1	596	600	PF01753	0.698
LIG_Pex14_1	510	514	PF04695	0.600
LIG_SH2_CRK	635	639	PF00017	0.681
LIG_SH2_CRK	86	90	PF00017	0.603
LIG_SH2_NCK_1	635	639	PF00017	0.573
LIG_SH2_SRC	960	963	PF00017	0.541
LIG_SH2_STAP1	635	639	PF00017	0.654
LIG_SH2_STAP1	960	964	PF00017	0.619
LIG_SH2_STAT5	106	109	PF00017	0.511
LIG_SH2_STAT5	635	638	PF00017	0.570
LIG_SH2_STAT5	86	89	PF00017	0.606
LIG_SH2_STAT5	865	868	PF00017	0.680
LIG_SH3_2	111	116	PF14604	0.680
LIG_SH3_2	584	589	PF14604	0.699
LIG_SH3_3	1010	1016	PF00018	0.691
LIG_SH3_3	108	114	PF00018	0.699
LIG_SH3_3	119	125	PF00018	0.612
LIG_SH3_3	130	136	PF00018	0.591
LIG_SH3_3	145	151	PF00018	0.650
LIG_SH3_3	231	237	PF00018	0.678
LIG_SH3_3	239	245	PF00018	0.623
LIG_SH3_3	320	326	PF00018	0.564
LIG_SH3_3	455	461	PF00018	0.682
LIG_SH3_3	581	587	PF00018	0.724
LIG_SH3_3	590	596	PF00018	0.645
LIG_SH3_3	705	711	PF00018	0.679
LIG_SH3_3	749	755	PF00018	0.668
LIG_SH3_3	910	916	PF00018	0.694
LIG_SUMO_SIM_anti_2	94	99	PF11976	0.597
LIG_SUMO_SIM_par_1	168	173	PF11976	0.619
LIG_SUMO_SIM_par_1	785	793	PF11976	0.670
LIG_SUMO_SIM_par_1	96	102	PF11976	0.613
LIG_SxIP_EBH_1	1005	1018	PF03271	0.584
LIG_SxIP_EBH_1	589	598	PF03271	0.589
LIG_TRAF2_1	62	65	PF00917	0.497
LIG_WW_3	113	117	PF00397	0.683
LIG_WW_3	559	563	PF00397	0.835
MOD_CDC14_SPxK_1	758	761	PF00782	0.668
MOD_CDK_SPxK_1	755	761	PF00069	0.677
MOD_CK1_1	1001	1007	PF00069	0.572
MOD_CK1_1	1028	1034	PF00069	0.592
MOD_CK1_1	144	150	PF00069	0.708
MOD_CK1_1	173	179	PF00069	0.675
MOD_CK1_1	189	195	PF00069	0.537
MOD_CK1_1	248	254	PF00069	0.679
MOD_CK1_1	289	295	PF00069	0.630
MOD_CK1_1	329	335	PF00069	0.658
MOD_CK1_1	414	420	PF00069	0.826
MOD_CK1_1	460	466	PF00069	0.678
MOD_CK1_1	476	482	PF00069	0.574
MOD_CK1_1	554	560	PF00069	0.801
MOD_CK1_1	686	692	PF00069	0.644
MOD_CK1_1	777	783	PF00069	0.624
MOD_CK1_1	789	795	PF00069	0.614
MOD_CK1_1	804	810	PF00069	0.537
MOD_CK1_1	84	90	PF00069	0.603
MOD_CK1_1	91	97	PF00069	0.537
MOD_CK1_1	943	949	PF00069	0.676
MOD_CK1_1	976	982	PF00069	0.644
MOD_CK1_1	983	989	PF00069	0.669
MOD_CK2_1	124	130	PF00069	0.709
MOD_CK2_1	447	453	PF00069	0.540
MOD_CK2_1	670	676	PF00069	0.599
MOD_CK2_1	884	890	PF00069	0.568
MOD_Cter_Amidation	389	392	PF01082	0.685
MOD_GlcNHglycan	1027	1030	PF01048	0.621
MOD_GlcNHglycan	163	166	PF01048	0.677
MOD_GlcNHglycan	17	20	PF01048	0.574
MOD_GlcNHglycan	172	175	PF01048	0.609
MOD_GlcNHglycan	188	191	PF01048	0.526
MOD_GlcNHglycan	229	232	PF01048	0.681
MOD_GlcNHglycan	247	250	PF01048	0.558
MOD_GlcNHglycan	288	291	PF01048	0.751
MOD_GlcNHglycan	323	326	PF01048	0.649
MOD_GlcNHglycan	329	332	PF01048	0.651
MOD_GlcNHglycan	418	421	PF01048	0.741
MOD_GlcNHglycan	422	425	PF01048	0.730
MOD_GlcNHglycan	475	478	PF01048	0.711
MOD_GlcNHglycan	52	55	PF01048	0.654
MOD_GlcNHglycan	531	534	PF01048	0.753
MOD_GlcNHglycan	563	566	PF01048	0.694
MOD_GlcNHglycan	655	658	PF01048	0.700
MOD_GlcNHglycan	733	736	PF01048	0.692
MOD_GlcNHglycan	754	758	PF01048	0.690
MOD_GlcNHglycan	784	787	PF01048	0.562
MOD_GlcNHglycan	806	809	PF01048	0.662
MOD_GlcNHglycan	848	851	PF01048	0.646
MOD_GlcNHglycan	854	857	PF01048	0.652
MOD_GlcNHglycan	867	870	PF01048	0.548
MOD_GlcNHglycan	893	896	PF01048	0.645
MOD_GlcNHglycan	9	12	PF01048	0.668
MOD_GlcNHglycan	979	982	PF01048	0.572
MOD_GSK3_1	1001	1008	PF00069	0.585
MOD_GSK3_1	125	132	PF00069	0.695
MOD_GSK3_1	182	189	PF00069	0.674
MOD_GSK3_1	253	260	PF00069	0.561
MOD_GSK3_1	321	328	PF00069	0.663
MOD_GSK3_1	374	381	PF00069	0.779
MOD_GSK3_1	407	414	PF00069	0.698
MOD_GSK3_1	416	423	PF00069	0.669
MOD_GSK3_1	471	478	PF00069	0.718
MOD_GSK3_1	480	487	PF00069	0.617
MOD_GSK3_1	492	499	PF00069	0.586
MOD_GSK3_1	587	594	PF00069	0.783
MOD_GSK3_1	641	648	PF00069	0.787
MOD_GSK3_1	649	656	PF00069	0.737
MOD_GSK3_1	683	690	PF00069	0.729
MOD_GSK3_1	7	14	PF00069	0.584
MOD_GSK3_1	753	760	PF00069	0.585
MOD_GSK3_1	77	84	PF00069	0.638
MOD_GSK3_1	775	782	PF00069	0.673
MOD_GSK3_1	880	887	PF00069	0.680
MOD_GSK3_1	939	946	PF00069	0.686
MOD_GSK3_1	973	980	PF00069	0.633
MOD_LATS_1	494	500	PF00433	0.665
MOD_N-GLC_1	1001	1006	PF02516	0.544
MOD_N-GLC_1	940	945	PF02516	0.686
MOD_N-GLC_1	989	994	PF02516	0.600
MOD_NEK2_1	182	187	PF00069	0.709
MOD_NEK2_1	208	213	PF00069	0.582
MOD_NEK2_1	588	593	PF00069	0.699
MOD_NEK2_1	685	690	PF00069	0.652
MOD_NEK2_1	7	12	PF00069	0.673
MOD_NEK2_1	939	944	PF00069	0.690
MOD_NEK2_2	402	407	PF00069	0.676
MOD_NEK2_2	786	791	PF00069	0.670
MOD_PIKK_1	11	17	PF00454	0.560
MOD_PIKK_1	633	639	PF00454	0.634
MOD_PIKK_1	834	840	PF00454	0.719
MOD_PIKK_1	940	946	PF00454	0.683
MOD_PK_1	1005	1011	PF00069	0.688
MOD_PK_1	81	87	PF00069	0.619
MOD_PKA_1	470	476	PF00069	0.724
MOD_PKA_1	496	502	PF00069	0.663
MOD_PKA_2	1025	1031	PF00069	0.600
MOD_PKA_2	115	121	PF00069	0.683
MOD_PKA_2	381	387	PF00069	0.795
MOD_PKA_2	438	444	PF00069	0.738
MOD_PKA_2	470	476	PF00069	0.864
MOD_PKA_2	49	55	PF00069	0.633
MOD_PKA_2	496	502	PF00069	0.808
MOD_PKA_2	561	567	PF00069	0.837
MOD_PKA_2	904	910	PF00069	0.679
MOD_PKB_1	437	445	PF00069	0.576
MOD_PKB_1	470	478	PF00069	0.719
MOD_Plk_1	260	266	PF00069	0.643
MOD_Plk_1	619	625	PF00069	0.790
MOD_Plk_1	740	746	PF00069	0.660
MOD_Plk_2-3	620	626	PF00069	0.643
MOD_Plk_4	402	408	PF00069	0.677
MOD_Plk_4	439	445	PF00069	0.679
MOD_Plk_4	55	61	PF00069	0.636
MOD_Plk_4	649	655	PF00069	0.699
MOD_Plk_4	81	87	PF00069	0.619
MOD_Plk_4	814	820	PF00069	0.659
MOD_Plk_4	904	910	PF00069	0.679
MOD_Plk_4	93	99	PF00069	0.493
MOD_Plk_4	955	961	PF00069	0.654
MOD_Plk_4	980	986	PF00069	0.586
MOD_ProDKin_1	107	113	PF00069	0.695
MOD_ProDKin_1	118	124	PF00069	0.613
MOD_ProDKin_1	129	135	PF00069	0.615
MOD_ProDKin_1	144	150	PF00069	0.596
MOD_ProDKin_1	236	242	PF00069	0.663
MOD_ProDKin_1	248	254	PF00069	0.563
MOD_ProDKin_1	277	283	PF00069	0.649
MOD_ProDKin_1	329	335	PF00069	0.642
MOD_ProDKin_1	457	463	PF00069	0.681
MOD_ProDKin_1	548	554	PF00069	0.667
MOD_ProDKin_1	592	598	PF00069	0.838
MOD_ProDKin_1	755	761	PF00069	0.677
MOD_ProDKin_1	801	807	PF00069	0.593
MOD_ProDKin_1	860	866	PF00069	0.642
MOD_ProDKin_1	896	902	PF00069	0.595
MOD_ProDKin_1	909	915	PF00069	0.632
MOD_ProDKin_1	983	989	PF00069	0.703
MOD_SUMO_rev_2	641	647	PF00179	0.676
TRG_DiLeu_BaLyEn_6	178	183	PF01217	0.568
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.641
TRG_DiLeu_BaLyEn_6	390	395	PF01217	0.570
TRG_ENDOCYTIC_2	635	638	PF00928	0.678
TRG_ENDOCYTIC_2	86	89	PF00928	0.606
TRG_ER_diArg_1	1013	1015	PF00400	0.692
TRG_ER_diArg_1	180	182	PF00400	0.572
TRG_ER_diArg_1	470	472	PF00400	0.731
TRG_ER_diArg_1	496	498	PF00400	0.677
TRG_ER_diArg_1	537	539	PF00400	0.770
TRG_ER_diArg_1	700	702	PF00400	0.690
TRG_ER_diArg_1	797	800	PF00400	0.573
TRG_Pf-PMV_PEXEL_1	1015	1019	PF00026	0.702
TRG_Pf-PMV_PEXEL_1	520	525	PF00026	0.680

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H6K9	Leishmania donovani	84%	100%
E9AGD8	Leishmania infantum	84%	70%
E9ANX8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	72%	95%