Mitochondrial protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Present in the outer mitochondrial membrane proteome 18

Species:

Leishmania major

UniProt:

Q4QGN8_LEIMA

TriTrypDb:

LmjF.12.0540 , LMJLV39_120011000 , LMJSD75_120010900

Length:

167

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0005741	mitochondrial outer membrane	5	2
GO:0016020	membrane	2	2
GO:0019867	outer membrane	3	2
GO:0031090	organelle membrane	3	2
GO:0031966	mitochondrial membrane	4	2
GO:0031968	organelle outer membrane	4	2
GO:0098588	bounding membrane of organelle	4	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

Q4QGN8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGN8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	144	146	PF00675	0.618
CLV_NRD_NRD_1	45	47	PF00675	0.626
CLV_PCSK_KEX2_1	133	135	PF00082	0.569
CLV_PCSK_PC1ET2_1	133	135	PF00082	0.569
CLV_PCSK_SKI1_1	3	7	PF00082	0.613
DEG_Nend_UBRbox_3	1	3	PF02207	0.513
DOC_PP1_RVXF_1	100	107	PF00149	0.506
DOC_PP1_RVXF_1	78	85	PF00149	0.474
DOC_USP7_UBL2_3	153	157	PF12436	0.553
DOC_USP7_UBL2_3	19	23	PF12436	0.600

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0S4JMJ7	Bodo saltans	43%	100%
A0A3S7WRX5	Leishmania donovani	93%	100%
E9AGE2	Leishmania infantum	93%	100%
E9ANY2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%

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