Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QGN7_LEIMA

TriTrypDb:

LmjF.12.0550 , LMJLV39_120011100 , LMJSD75_120011000

Length:

499

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGN7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGN7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	82	86	PF00656	0.523
CLV_NRD_NRD_1	107	109	PF00675	0.558
CLV_NRD_NRD_1	119	121	PF00675	0.488
CLV_NRD_NRD_1	156	158	PF00675	0.519
CLV_NRD_NRD_1	18	20	PF00675	0.456
CLV_NRD_NRD_1	330	332	PF00675	0.593
CLV_PCSK_KEX2_1	107	109	PF00082	0.558
CLV_PCSK_KEX2_1	119	121	PF00082	0.488
CLV_PCSK_KEX2_1	18	20	PF00082	0.456
CLV_PCSK_KEX2_1	491	493	PF00082	0.648
CLV_PCSK_PC1ET2_1	491	493	PF00082	0.648
CLV_PCSK_PC7_1	487	493	PF00082	0.632
CLV_PCSK_SKI1_1	119	123	PF00082	0.654
CLV_PCSK_SKI1_1	471	475	PF00082	0.424
CLV_Separin_Metazoa	413	417	PF03568	0.794
CLV_Separin_Metazoa	468	472	PF03568	0.628
DEG_APCC_KENBOX_2	270	274	PF00400	0.829
DEG_SCF_FBW7_1	166	173	PF00400	0.752
DEG_SPOP_SBC_1	170	174	PF00917	0.770
DEG_SPOP_SBC_1	368	372	PF00917	0.634
DOC_CYCLIN_RxL_1	468	477	PF00134	0.361
DOC_MAPK_FxFP_2	422	425	PF00069	0.809
DOC_MAPK_gen_1	145	153	PF00069	0.637
DOC_PP4_FxxP_1	296	299	PF00568	0.819
DOC_PP4_FxxP_1	422	425	PF00568	0.809
DOC_USP7_MATH_1	170	174	PF00917	0.695
DOC_USP7_MATH_1	189	193	PF00917	0.486
DOC_USP7_MATH_1	198	202	PF00917	0.781
DOC_USP7_MATH_1	207	211	PF00917	0.669
DOC_USP7_MATH_1	232	236	PF00917	0.820
DOC_USP7_MATH_1	310	314	PF00917	0.680
DOC_USP7_MATH_1	334	338	PF00917	0.716
DOC_USP7_MATH_1	347	351	PF00917	0.777
DOC_USP7_MATH_1	369	373	PF00917	0.635
DOC_USP7_MATH_1	389	393	PF00917	0.800
DOC_USP7_MATH_1	456	460	PF00917	0.618
DOC_USP7_UBL2_3	143	147	PF12436	0.644
DOC_USP7_UBL2_3	271	275	PF12436	0.824
DOC_WW_Pin1_4	166	171	PF00397	0.623
DOC_WW_Pin1_4	213	218	PF00397	0.776
DOC_WW_Pin1_4	223	228	PF00397	0.553
DOC_WW_Pin1_4	233	238	PF00397	0.703
DOC_WW_Pin1_4	255	260	PF00397	0.818
DOC_WW_Pin1_4	277	282	PF00397	0.645
DOC_WW_Pin1_4	295	300	PF00397	0.817
DOC_WW_Pin1_4	364	369	PF00397	0.848
DOC_WW_Pin1_4	371	376	PF00397	0.721
LIG_14-3-3_CanoR_1	19	25	PF00244	0.597
LIG_14-3-3_CanoR_1	244	248	PF00244	0.827
LIG_14-3-3_CanoR_1	338	348	PF00244	0.834
LIG_14-3-3_CanoR_1	384	390	PF00244	0.745
LIG_14-3-3_CanoR_1	79	87	PF00244	0.485
LIG_14-3-3_CanoR_1	97	106	PF00244	0.474
LIG_AP2alpha_2	420	422	PF02296	0.795
LIG_BRCT_BRCA1_1	171	175	PF00533	0.774
LIG_CSL_BTD_1	318	321	PF09270	0.797
LIG_EVH1_1	424	428	PF00568	0.813
LIG_FHA_1	135	141	PF00498	0.552
LIG_FHA_1	368	374	PF00498	0.667
LIG_FHA_1	385	391	PF00498	0.698
LIG_FHA_2	112	118	PF00498	0.648
LIG_FHA_2	441	447	PF00498	0.549
LIG_LIR_Apic_2	226	231	PF02991	0.793
LIG_LIR_Apic_2	295	299	PF02991	0.816
LIG_LIR_Apic_2	420	425	PF02991	0.802
LIG_LIR_Gen_1	25	34	PF02991	0.335
LIG_LIR_Gen_1	9	17	PF02991	0.607
LIG_LIR_Nem_3	25	30	PF02991	0.616
LIG_LIR_Nem_3	488	493	PF02991	0.508
LIG_NRBOX	469	475	PF00104	0.552
LIG_PCNA_yPIPBox_3	464	474	PF02747	0.370
LIG_RPA_C_Fungi	388	400	PF08784	0.542
LIG_SH2_CRK	222	226	PF00017	0.808
LIG_SH2_CRK	228	232	PF00017	0.704
LIG_SH2_CRK	490	494	PF00017	0.634
LIG_SH2_STAP1	27	31	PF00017	0.596
LIG_SH2_STAP1	385	389	PF00017	0.807
LIG_SH2_STAT5	385	388	PF00017	0.812
LIG_SH3_2	224	229	PF14604	0.605
LIG_SH3_3	211	217	PF00018	0.653
LIG_SH3_3	221	227	PF00018	0.577
LIG_SH3_3	231	237	PF00018	0.665
LIG_SH3_3	253	259	PF00018	0.669
LIG_SH3_3	314	320	PF00018	0.796
LIG_SH3_3	363	369	PF00018	0.646
LIG_SH3_3	422	428	PF00018	0.662
LIG_SH3_CIN85_PxpxPR_1	421	426	PF14604	0.810
LIG_SUMO_SIM_anti_2	313	319	PF11976	0.733
LIG_TRAF2_1	102	105	PF00917	0.725
LIG_TRAF2_1	121	124	PF00917	0.352
LIG_UBA3_1	469	476	PF00899	0.549
MOD_CDC14_SPxK_1	226	229	PF00782	0.603
MOD_CDK_SPxK_1	223	229	PF00069	0.609
MOD_CDK_SPxxK_3	213	220	PF00069	0.758
MOD_CDK_SPxxK_3	299	306	PF00069	0.817
MOD_CK1_1	168	174	PF00069	0.628
MOD_CK1_1	192	198	PF00069	0.549
MOD_CK1_1	212	218	PF00069	0.693
MOD_CK1_1	235	241	PF00069	0.819
MOD_CK1_1	245	251	PF00069	0.747
MOD_CK1_1	277	283	PF00069	0.671
MOD_CK1_1	286	292	PF00069	0.652
MOD_CK1_1	295	301	PF00069	0.761
MOD_CK1_1	3	9	PF00069	0.671
MOD_CK1_1	333	339	PF00069	0.703
MOD_CK1_1	341	347	PF00069	0.713
MOD_CK1_1	367	373	PF00069	0.779
MOD_CK1_1	439	445	PF00069	0.605
MOD_CK1_1	81	87	PF00069	0.633
MOD_CK2_1	111	117	PF00069	0.647
MOD_CK2_1	198	204	PF00069	0.630
MOD_CK2_1	233	239	PF00069	0.819
MOD_CK2_1	255	261	PF00069	0.686
MOD_CK2_1	3	9	PF00069	0.671
MOD_CK2_1	440	446	PF00069	0.586
MOD_CK2_1	457	463	PF00069	0.528
MOD_DYRK1A_RPxSP_1	223	227	PF00069	0.545
MOD_GlcNHglycan	124	129	PF01048	0.578
MOD_GlcNHglycan	209	212	PF01048	0.720
MOD_GlcNHglycan	250	254	PF01048	0.561
MOD_GlcNHglycan	312	315	PF01048	0.673
MOD_GlcNHglycan	332	335	PF01048	0.534
MOD_GlcNHglycan	349	352	PF01048	0.597
MOD_GlcNHglycan	357	361	PF01048	0.701
MOD_GlcNHglycan	387	390	PF01048	0.777
MOD_GlcNHglycan	429	432	PF01048	0.654
MOD_GlcNHglycan	452	456	PF01048	0.733
MOD_GlcNHglycan	459	462	PF01048	0.521
MOD_GlcNHglycan	75	78	PF01048	0.539
MOD_GlcNHglycan	91	94	PF01048	0.672
MOD_GSK3_1	107	114	PF00069	0.660
MOD_GSK3_1	164	171	PF00069	0.733
MOD_GSK3_1	192	199	PF00069	0.550
MOD_GSK3_1	209	216	PF00069	0.765
MOD_GSK3_1	242	249	PF00069	0.794
MOD_GSK3_1	288	295	PF00069	0.720
MOD_GSK3_1	326	333	PF00069	0.697
MOD_GSK3_1	334	341	PF00069	0.680
MOD_GSK3_1	364	371	PF00069	0.834
MOD_GSK3_1	385	392	PF00069	0.806
MOD_GSK3_1	427	434	PF00069	0.654
MOD_GSK3_1	436	443	PF00069	0.768
MOD_GSK3_1	447	454	PF00069	0.694
MOD_N-GLC_1	436	441	PF02516	0.556
MOD_N-GLC_1	97	102	PF02516	0.499
MOD_NEK2_1	164	169	PF00069	0.531
MOD_NEK2_1	243	248	PF00069	0.827
MOD_NEK2_1	356	361	PF00069	0.586
MOD_NEK2_1	457	462	PF00069	0.401
MOD_NEK2_1	89	94	PF00069	0.574
MOD_PIKK_1	198	204	PF00454	0.757
MOD_PIKK_1	215	221	PF00454	0.820
MOD_PIKK_1	336	342	PF00454	0.835
MOD_PIKK_1	391	397	PF00454	0.796
MOD_PKA_1	107	113	PF00069	0.410
MOD_PKA_2	107	113	PF00069	0.513
MOD_PKA_2	134	140	PF00069	0.639
MOD_PKA_2	243	249	PF00069	0.825
MOD_PKA_2	330	336	PF00069	0.592
MOD_PKA_2	383	389	PF00069	0.755
MOD_PKA_2	73	79	PF00069	0.535
MOD_PKA_2	96	102	PF00069	0.605
MOD_Plk_1	289	295	PF00069	0.601
MOD_Plk_1	3	9	PF00069	0.671
MOD_Plk_1	436	442	PF00069	0.554
MOD_Plk_4	171	177	PF00069	0.520
MOD_Plk_4	292	298	PF00069	0.817
MOD_Plk_4	436	442	PF00069	0.751
MOD_ProDKin_1	166	172	PF00069	0.629
MOD_ProDKin_1	213	219	PF00069	0.777
MOD_ProDKin_1	223	229	PF00069	0.554
MOD_ProDKin_1	233	239	PF00069	0.703
MOD_ProDKin_1	255	261	PF00069	0.818
MOD_ProDKin_1	277	283	PF00069	0.646
MOD_ProDKin_1	295	301	PF00069	0.817
MOD_ProDKin_1	364	370	PF00069	0.845
MOD_ProDKin_1	371	377	PF00069	0.722
TRG_ENDOCYTIC_2	21	24	PF00928	0.596
TRG_ENDOCYTIC_2	27	30	PF00928	0.514
TRG_ENDOCYTIC_2	490	493	PF00928	0.636
TRG_ER_diArg_1	106	108	PF00400	0.545
TRG_ER_diArg_1	118	120	PF00400	0.618
TRG_ER_diArg_1	17	19	PF00400	0.613
TRG_Pf-PMV_PEXEL_1	120	124	PF00026	0.654
TRG_Pf-PMV_PEXEL_1	471	475	PF00026	0.624
TRG_Pf-PMV_PEXEL_1	491	495	PF00026	0.646

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WS06	Leishmania donovani	90%	100%
E9AGE3	Leishmania infantum	90%	100%
E9ANY3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%