Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QGG1_LEIMA

TriTrypDb:

LmjF.12.1280 , LMJLV39_120015000 , LMJSD75_120015900

Length:

654

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGG1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGG1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	447	451	PF00656	0.615
CLV_C14_Caspase3-7	554	558	PF00656	0.559
CLV_C14_Caspase3-7	649	653	PF00656	0.695
CLV_NRD_NRD_1	102	104	PF00675	0.730
CLV_NRD_NRD_1	133	135	PF00675	0.766
CLV_NRD_NRD_1	153	155	PF00675	0.487
CLV_NRD_NRD_1	16	18	PF00675	0.703
CLV_NRD_NRD_1	205	207	PF00675	0.738
CLV_NRD_NRD_1	25	27	PF00675	0.661
CLV_NRD_NRD_1	569	571	PF00675	0.573
CLV_NRD_NRD_1	59	61	PF00675	0.771
CLV_NRD_NRD_1	624	626	PF00675	0.583
CLV_NRD_NRD_1	632	634	PF00675	0.502
CLV_PCSK_FUR_1	131	135	PF00082	0.764
CLV_PCSK_FUR_1	630	634	PF00082	0.583
CLV_PCSK_KEX2_1	102	104	PF00082	0.730
CLV_PCSK_KEX2_1	131	133	PF00082	0.755
CLV_PCSK_KEX2_1	153	155	PF00082	0.647
CLV_PCSK_KEX2_1	205	207	PF00082	0.738
CLV_PCSK_KEX2_1	59	61	PF00082	0.771
CLV_PCSK_KEX2_1	624	626	PF00082	0.607
CLV_PCSK_KEX2_1	630	632	PF00082	0.510
CLV_PCSK_SKI1_1	103	107	PF00082	0.616
CLV_PCSK_SKI1_1	591	595	PF00082	0.744
CLV_PCSK_SKI1_1	625	629	PF00082	0.558
CLV_PCSK_SKI1_1	97	101	PF00082	0.668
DEG_COP1_1	362	369	PF00400	0.655
DEG_SCF_FBW7_1	460	467	PF00400	0.666
DEG_SCF_FBW7_1	592	598	PF00400	0.743
DEG_SPOP_SBC_1	157	161	PF00917	0.605
DOC_CKS1_1	234	239	PF01111	0.672
DOC_CKS1_1	361	366	PF01111	0.688
DOC_CKS1_1	421	426	PF01111	0.621
DOC_CKS1_1	461	466	PF01111	0.760
DOC_CKS1_1	51	56	PF01111	0.740
DOC_CKS1_1	592	597	PF01111	0.745
DOC_CYCLIN_RxL_1	94	104	PF00134	0.552
DOC_MAPK_gen_1	102	108	PF00069	0.734
DOC_PP1_RVXF_1	501	507	PF00149	0.591
DOC_PP2B_LxvP_1	116	119	PF13499	0.646
DOC_PP4_FxxP_1	269	272	PF00568	0.644
DOC_USP7_MATH_1	119	123	PF00917	0.746
DOC_USP7_MATH_1	177	181	PF00917	0.685
DOC_USP7_MATH_1	293	297	PF00917	0.614
DOC_USP7_MATH_1	32	36	PF00917	0.646
DOC_USP7_MATH_1	326	330	PF00917	0.662
DOC_USP7_MATH_1	386	390	PF00917	0.677
DOC_USP7_MATH_1	46	50	PF00917	0.698
DOC_USP7_MATH_1	574	578	PF00917	0.699
DOC_USP7_MATH_1	595	599	PF00917	0.712
DOC_USP7_MATH_1	602	606	PF00917	0.650
DOC_WW_Pin1_4	219	224	PF00397	0.659
DOC_WW_Pin1_4	230	235	PF00397	0.587
DOC_WW_Pin1_4	28	33	PF00397	0.771
DOC_WW_Pin1_4	281	286	PF00397	0.579
DOC_WW_Pin1_4	347	352	PF00397	0.733
DOC_WW_Pin1_4	360	365	PF00397	0.591
DOC_WW_Pin1_4	411	416	PF00397	0.681
DOC_WW_Pin1_4	420	425	PF00397	0.613
DOC_WW_Pin1_4	429	434	PF00397	0.530
DOC_WW_Pin1_4	460	465	PF00397	0.699
DOC_WW_Pin1_4	475	480	PF00397	0.552
DOC_WW_Pin1_4	493	498	PF00397	0.555
DOC_WW_Pin1_4	50	55	PF00397	0.743
DOC_WW_Pin1_4	557	562	PF00397	0.724
DOC_WW_Pin1_4	572	577	PF00397	0.586
DOC_WW_Pin1_4	591	596	PF00397	0.523
DOC_WW_Pin1_4	68	73	PF00397	0.547
LIG_14-3-3_CanoR_1	102	108	PF00244	0.734
LIG_14-3-3_CanoR_1	11	15	PF00244	0.580
LIG_14-3-3_CanoR_1	123	130	PF00244	0.640
LIG_14-3-3_CanoR_1	158	164	PF00244	0.585
LIG_14-3-3_CanoR_1	360	364	PF00244	0.665
LIG_14-3-3_CanoR_1	435	441	PF00244	0.705
LIG_14-3-3_CanoR_1	550	554	PF00244	0.661
LIG_BIR_III_2	450	454	PF00653	0.618
LIG_BRCT_BRCA1_1	476	480	PF00533	0.569
LIG_CSL_BTD_1	348	351	PF09270	0.676
LIG_CSL_BTD_1	392	395	PF09270	0.703
LIG_DLG_GKlike_1	17	25	PF00625	0.674
LIG_FHA_1	119	125	PF00498	0.686
LIG_FHA_1	216	222	PF00498	0.712
LIG_FHA_1	340	346	PF00498	0.597
LIG_FHA_1	361	367	PF00498	0.724
LIG_FHA_1	421	427	PF00498	0.677
LIG_FHA_1	461	467	PF00498	0.774
LIG_FHA_1	594	600	PF00498	0.577
LIG_FHA_1	78	84	PF00498	0.666
LIG_FHA_2	171	177	PF00498	0.670
LIG_FHA_2	290	296	PF00498	0.712
LIG_FHA_2	375	381	PF00498	0.706
LIG_IRF3_LxIS_1	182	187	PF10401	0.574
LIG_LIR_Apic_2	266	272	PF02991	0.646
LIG_LIR_Apic_2	347	352	PF02991	0.646
LIG_LIR_Gen_1	183	189	PF02991	0.545
LIG_LIR_Nem_3	183	188	PF02991	0.589
LIG_LIR_Nem_3	4	9	PF02991	0.551
LIG_LYPXL_yS_3	375	378	PF13949	0.674
LIG_MYND_1	407	411	PF01753	0.562
LIG_MYND_1	75	79	PF01753	0.560
LIG_NRBOX	301	307	PF00104	0.554
LIG_PDZ_Class_3	649	654	PF00595	0.702
LIG_SH2_CRK	6	10	PF00017	0.551
LIG_SH2_STAT5	6	9	PF00017	0.554
LIG_SH3_1	589	595	PF00018	0.688
LIG_SH3_2	54	59	PF14604	0.750
LIG_SH3_3	217	223	PF00018	0.667
LIG_SH3_3	231	237	PF00018	0.558
LIG_SH3_3	241	247	PF00018	0.653
LIG_SH3_3	320	326	PF00018	0.602
LIG_SH3_3	348	354	PF00018	0.717
LIG_SH3_3	361	367	PF00018	0.597
LIG_SH3_3	370	376	PF00018	0.592
LIG_SH3_3	380	386	PF00018	0.533
LIG_SH3_3	51	57	PF00018	0.742
LIG_SH3_3	589	595	PF00018	0.688
LIG_SH3_3	69	75	PF00018	0.539
LIG_SH3_4	18	25	PF00018	0.658
LIG_SH3_4	97	104	PF00018	0.670
LIG_SUMO_SIM_par_1	217	222	PF11976	0.657
LIG_TRAF2_1	240	243	PF00917	0.702
MOD_CDC14_SPxK_1	432	435	PF00782	0.578
MOD_CDC14_SPxK_1	575	578	PF00782	0.699
MOD_CDK_SPxK_1	429	435	PF00069	0.585
MOD_CDK_SPxK_1	572	578	PF00069	0.746
MOD_CDK_SPxxK_3	281	288	PF00069	0.556
MOD_CK1_1	180	186	PF00069	0.709
MOD_CK1_1	187	193	PF00069	0.642
MOD_CK1_1	214	220	PF00069	0.656
MOD_CK1_1	222	228	PF00069	0.663
MOD_CK1_1	233	239	PF00069	0.556
MOD_CK1_1	281	287	PF00069	0.695
MOD_CK1_1	308	314	PF00069	0.664
MOD_CK1_1	329	335	PF00069	0.680
MOD_CK1_1	341	347	PF00069	0.660
MOD_CK1_1	362	368	PF00069	0.670
MOD_CK1_1	389	395	PF00069	0.635
MOD_CK1_1	413	419	PF00069	0.694
MOD_CK1_1	443	449	PF00069	0.700
MOD_CK1_1	523	529	PF00069	0.732
MOD_CK1_1	562	568	PF00069	0.669
MOD_CK1_1	584	590	PF00069	0.765
MOD_CK1_1	605	611	PF00069	0.695
MOD_CK1_1	614	620	PF00069	0.536
MOD_CK1_1	73	79	PF00069	0.652
MOD_CK2_1	123	129	PF00069	0.758
MOD_CK2_1	170	176	PF00069	0.672
MOD_CK2_1	188	194	PF00069	0.491
MOD_CK2_1	289	295	PF00069	0.636
MOD_CK2_1	301	307	PF00069	0.516
MOD_CK2_1	422	428	PF00069	0.640
MOD_DYRK1A_RPxSP_1	591	595	PF00069	0.657
MOD_GlcNHglycan	111	114	PF01048	0.676
MOD_GlcNHglycan	141	144	PF01048	0.733
MOD_GlcNHglycan	145	148	PF01048	0.739
MOD_GlcNHglycan	165	168	PF01048	0.478
MOD_GlcNHglycan	212	216	PF01048	0.714
MOD_GlcNHglycan	259	262	PF01048	0.678
MOD_GlcNHglycan	295	298	PF01048	0.646
MOD_GlcNHglycan	313	316	PF01048	0.679
MOD_GlcNHglycan	326	329	PF01048	0.623
MOD_GlcNHglycan	335	338	PF01048	0.633
MOD_GlcNHglycan	415	418	PF01048	0.632
MOD_GlcNHglycan	482	485	PF01048	0.717
MOD_GlcNHglycan	508	511	PF01048	0.710
MOD_GlcNHglycan	522	525	PF01048	0.633
MOD_GlcNHglycan	553	556	PF01048	0.705
MOD_GlcNHglycan	607	610	PF01048	0.655
MOD_GlcNHglycan	613	616	PF01048	0.554
MOD_GlcNHglycan	618	621	PF01048	0.473
MOD_GSK3_1	104	111	PF00069	0.668
MOD_GSK3_1	119	126	PF00069	0.631
MOD_GSK3_1	135	142	PF00069	0.567
MOD_GSK3_1	143	150	PF00069	0.572
MOD_GSK3_1	158	165	PF00069	0.507
MOD_GSK3_1	180	187	PF00069	0.720
MOD_GSK3_1	211	218	PF00069	0.720
MOD_GSK3_1	22	29	PF00069	0.707
MOD_GSK3_1	263	270	PF00069	0.645
MOD_GSK3_1	271	278	PF00069	0.623
MOD_GSK3_1	289	296	PF00069	0.644
MOD_GSK3_1	301	308	PF00069	0.606
MOD_GSK3_1	326	333	PF00069	0.738
MOD_GSK3_1	340	347	PF00069	0.550
MOD_GSK3_1	374	381	PF00069	0.650
MOD_GSK3_1	46	53	PF00069	0.703
MOD_GSK3_1	460	467	PF00069	0.597
MOD_GSK3_1	474	481	PF00069	0.540
MOD_GSK3_1	516	523	PF00069	0.651
MOD_GSK3_1	526	533	PF00069	0.644
MOD_GSK3_1	549	556	PF00069	0.695
MOD_GSK3_1	559	566	PF00069	0.627
MOD_GSK3_1	572	579	PF00069	0.656
MOD_GSK3_1	591	598	PF00069	0.636
MOD_GSK3_1	610	617	PF00069	0.464
MOD_GSK3_1	73	80	PF00069	0.650
MOD_N-GLC_1	584	589	PF02516	0.766
MOD_N-GLC_1	645	650	PF02516	0.635
MOD_NEK2_1	188	193	PF00069	0.542
MOD_NEK2_1	211	216	PF00069	0.713
MOD_NEK2_1	275	280	PF00069	0.661
MOD_NEK2_1	305	310	PF00069	0.707
MOD_NEK2_1	480	485	PF00069	0.649
MOD_NEK2_1	610	615	PF00069	0.583
MOD_PIKK_1	177	183	PF00454	0.631
MOD_PIKK_1	440	446	PF00454	0.759
MOD_PIKK_1	516	522	PF00454	0.674
MOD_PIKK_1	526	532	PF00454	0.594
MOD_PKA_1	17	23	PF00069	0.702
MOD_PKA_1	26	32	PF00069	0.629
MOD_PKA_2	10	16	PF00069	0.579
MOD_PKA_2	101	107	PF00069	0.731
MOD_PKA_2	157	163	PF00069	0.727
MOD_PKA_2	308	314	PF00069	0.664
MOD_PKA_2	333	339	PF00069	0.719
MOD_PKA_2	359	365	PF00069	0.695
MOD_PKA_2	434	440	PF00069	0.733
MOD_PKA_2	520	526	PF00069	0.813
MOD_PKA_2	534	540	PF00069	0.631
MOD_PKA_2	549	555	PF00069	0.535
MOD_PKB_1	60	68	PF00069	0.775
MOD_Plk_1	147	153	PF00069	0.609
MOD_Plk_1	319	325	PF00069	0.691
MOD_Plk_1	645	651	PF00069	0.644
MOD_Plk_2-3	422	428	PF00069	0.589
MOD_Plk_4	10	16	PF00069	0.562
MOD_Plk_4	147	153	PF00069	0.580
MOD_Plk_4	180	186	PF00069	0.575
MOD_Plk_4	215	221	PF00069	0.708
MOD_Plk_4	301	307	PF00069	0.554
MOD_Plk_4	344	350	PF00069	0.684
MOD_Plk_4	37	43	PF00069	0.577
MOD_Plk_4	374	380	PF00069	0.679
MOD_Plk_4	389	395	PF00069	0.531
MOD_Plk_4	405	411	PF00069	0.554
MOD_Plk_4	422	428	PF00069	0.551
MOD_Plk_4	534	540	PF00069	0.699
MOD_ProDKin_1	219	225	PF00069	0.660
MOD_ProDKin_1	230	236	PF00069	0.588
MOD_ProDKin_1	28	34	PF00069	0.770
MOD_ProDKin_1	281	287	PF00069	0.575
MOD_ProDKin_1	347	353	PF00069	0.735
MOD_ProDKin_1	360	366	PF00069	0.588
MOD_ProDKin_1	411	417	PF00069	0.684
MOD_ProDKin_1	420	426	PF00069	0.616
MOD_ProDKin_1	429	435	PF00069	0.531
MOD_ProDKin_1	460	466	PF00069	0.702
MOD_ProDKin_1	475	481	PF00069	0.553
MOD_ProDKin_1	493	499	PF00069	0.556
MOD_ProDKin_1	50	56	PF00069	0.743
MOD_ProDKin_1	557	563	PF00069	0.723
MOD_ProDKin_1	572	578	PF00069	0.586
MOD_ProDKin_1	591	597	PF00069	0.510
MOD_ProDKin_1	68	74	PF00069	0.543
TRG_DiLeu_BaLyEn_6	120	125	PF01217	0.635
TRG_DiLeu_BaLyEn_6	95	100	PF01217	0.554
TRG_ENDOCYTIC_2	375	378	PF00928	0.674
TRG_ENDOCYTIC_2	6	9	PF00928	0.554
TRG_ER_diArg_1	130	133	PF00400	0.749
TRG_ER_diArg_1	152	154	PF00400	0.714
TRG_ER_diArg_1	204	206	PF00400	0.740
TRG_ER_diArg_1	501	504	PF00400	0.652
TRG_ER_diArg_1	589	592	PF00400	0.721
TRG_ER_diArg_1	59	62	PF00400	0.772
TRG_ER_diArg_1	630	633	PF00400	0.585
TRG_Pf-PMV_PEXEL_1	625	629	PF00026	0.558

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WSA2	Leishmania donovani	84%	100%
E9AGJ0	Leishmania infantum	84%	100%
E9AIN8	Leishmania braziliensis	50%	100%
E9AP28	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%