Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QGE7_LEIMA

TriTrypDb:

LmjF.13.0070 , LMJLV39_130005700 , LMJSD75_130005800

Length:

307

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGE7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGE7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	110	114	PF00656	0.766
CLV_NRD_NRD_1	186	188	PF00675	0.562
CLV_NRD_NRD_1	210	212	PF00675	0.648
CLV_NRD_NRD_1	215	217	PF00675	0.617
CLV_NRD_NRD_1	262	264	PF00675	0.555
CLV_PCSK_FUR_1	184	188	PF00082	0.567
CLV_PCSK_KEX2_1	186	188	PF00082	0.535
CLV_PCSK_KEX2_1	214	216	PF00082	0.641
CLV_PCSK_KEX2_1	262	264	PF00082	0.567
CLV_PCSK_PC7_1	211	217	PF00082	0.577
CLV_PCSK_SKI1_1	248	252	PF00082	0.763
CLV_PCSK_SKI1_1	37	41	PF00082	0.715
DEG_SCF_FBW7_1	51	56	PF00400	0.599
DOC_CKS1_1	179	184	PF01111	0.597
DOC_CKS1_1	94	99	PF01111	0.766
DOC_CYCLIN_yCln2_LP_2	74	80	PF00134	0.560
DOC_PP1_RVXF_1	35	42	PF00149	0.582
DOC_PP4_FxxP_1	297	300	PF00568	0.764
DOC_PP4_FxxP_1	40	43	PF00568	0.755
DOC_PP4_FxxP_1	86	89	PF00568	0.762
DOC_USP7_MATH_1	149	153	PF00917	0.750
DOC_USP7_MATH_1	277	281	PF00917	0.666
DOC_USP7_MATH_1	28	32	PF00917	0.554
DOC_USP7_MATH_1	303	307	PF00917	0.797
DOC_USP7_MATH_1	43	47	PF00917	0.575
DOC_WW_Pin1_4	119	124	PF00397	0.642
DOC_WW_Pin1_4	160	165	PF00397	0.783
DOC_WW_Pin1_4	178	183	PF00397	0.578
DOC_WW_Pin1_4	241	246	PF00397	0.714
DOC_WW_Pin1_4	283	288	PF00397	0.663
DOC_WW_Pin1_4	296	301	PF00397	0.417
DOC_WW_Pin1_4	39	44	PF00397	0.588
DOC_WW_Pin1_4	49	54	PF00397	0.462
DOC_WW_Pin1_4	73	78	PF00397	0.735
DOC_WW_Pin1_4	93	98	PF00397	0.766
LIG_14-3-3_CanoR_1	186	193	PF00244	0.549
LIG_BRCT_BRCA1_1	293	297	PF00533	0.659
LIG_BRCT_BRCA1_1	80	84	PF00533	0.564
LIG_Clathr_ClatBox_1	54	58	PF01394	0.600
LIG_FHA_1	104	110	PF00498	0.580
LIG_FHA_2	108	114	PF00498	0.762
LIG_FHA_2	143	149	PF00498	0.674
LIG_FHA_2	205	211	PF00498	0.651
LIG_LIR_Apic_2	294	300	PF02991	0.766
LIG_LIR_Apic_2	38	43	PF02991	0.585
LIG_LIR_Apic_2	83	89	PF02991	0.732
LIG_LIR_Gen_1	22	28	PF02991	0.696
LIG_LIR_Nem_3	22	26	PF02991	0.695
LIG_LIR_Nem_3	81	87	PF02991	0.712
LIG_MLH1_MIPbox_1	82	86	PF16413	0.575
LIG_PDZ_Class_1	302	307	PF00595	0.794
LIG_Pex14_2	23	27	PF04695	0.552
LIG_Pex14_2	293	297	PF04695	0.659
LIG_Pex14_2	55	59	PF04695	0.771
LIG_Pex14_2	86	90	PF04695	0.713
LIG_RPA_C_Fungi	148	160	PF08784	0.591
LIG_SH2_STAT3	295	298	PF00017	0.660
LIG_SH2_STAT5	225	228	PF00017	0.746
LIG_SH2_STAT5	275	278	PF00017	0.658
LIG_SH3_3	115	121	PF00018	0.603
LIG_SH3_3	176	182	PF00018	0.624
LIG_SH3_3	284	290	PF00018	0.662
LIG_SH3_3	42	48	PF00018	0.662
LIG_SH3_3	91	97	PF00018	0.764
LIG_SUMO_SIM_par_1	76	81	PF11976	0.563
MOD_CDK_SPK_2	283	288	PF00069	0.663
MOD_CDK_SPxK_1	178	184	PF00069	0.602
MOD_CDK_SPxxK_3	119	126	PF00069	0.754
MOD_CDK_SPxxK_3	241	248	PF00069	0.710
MOD_CK1_1	119	125	PF00069	0.755
MOD_CK1_1	218	224	PF00069	0.577
MOD_CK1_1	280	286	PF00069	0.613
MOD_CK1_1	291	297	PF00069	0.623
MOD_CK1_1	299	305	PF00069	0.654
MOD_CK1_1	31	37	PF00069	0.581
MOD_CK1_1	95	101	PF00069	0.657
MOD_CK2_1	142	148	PF00069	0.650
MOD_CK2_1	204	210	PF00069	0.599
MOD_DYRK1A_RPxSP_1	178	182	PF00069	0.612
MOD_GlcNHglycan	188	191	PF01048	0.650
MOD_GlcNHglycan	30	33	PF01048	0.672
MOD_GlcNHglycan	301	304	PF01048	0.666
MOD_GlcNHglycan	61	64	PF01048	0.744
MOD_GlcNHglycan	98	101	PF01048	0.661
MOD_GSK3_1	103	110	PF00069	0.473
MOD_GSK3_1	154	161	PF00069	0.763
MOD_GSK3_1	174	181	PF00069	0.751
MOD_GSK3_1	215	222	PF00069	0.747
MOD_GSK3_1	271	278	PF00069	0.595
MOD_GSK3_1	299	306	PF00069	0.775
MOD_GSK3_1	31	38	PF00069	0.564
MOD_GSK3_1	39	46	PF00069	0.610
MOD_GSK3_1	49	56	PF00069	0.501
MOD_GSK3_1	88	95	PF00069	0.764
MOD_N-GLC_1	154	159	PF02516	0.781
MOD_N-GLC_1	164	169	PF02516	0.584
MOD_NEK2_1	131	136	PF00069	0.672
MOD_NEK2_1	14	19	PF00069	0.566
MOD_NEK2_1	258	263	PF00069	0.545
MOD_NEK2_1	26	31	PF00069	0.451
MOD_NEK2_2	142	147	PF00069	0.624
MOD_NEK2_2	35	40	PF00069	0.577
MOD_OFUCOSY	25	30	PF10250	0.555
MOD_PIKK_1	147	153	PF00454	0.574
MOD_PIKK_1	89	95	PF00454	0.765
MOD_PK_1	219	225	PF00069	0.759
MOD_PKA_1	158	164	PF00069	0.613
MOD_PKA_1	186	192	PF00069	0.527
MOD_PKA_1	215	221	PF00069	0.630
MOD_PKA_2	186	192	PF00069	0.558
MOD_PKA_2	215	221	PF00069	0.630
MOD_PKB_1	184	192	PF00069	0.559
MOD_Plk_1	219	225	PF00069	0.759
MOD_Plk_4	80	86	PF00069	0.660
MOD_ProDKin_1	119	125	PF00069	0.642
MOD_ProDKin_1	160	166	PF00069	0.781
MOD_ProDKin_1	178	184	PF00069	0.575
MOD_ProDKin_1	241	247	PF00069	0.712
MOD_ProDKin_1	283	289	PF00069	0.662
MOD_ProDKin_1	296	302	PF00069	0.419
MOD_ProDKin_1	39	45	PF00069	0.583
MOD_ProDKin_1	49	55	PF00069	0.464
MOD_ProDKin_1	73	79	PF00069	0.735
MOD_ProDKin_1	93	99	PF00069	0.767
MOD_SUMO_rev_2	204	213	PF00179	0.616
TRG_ENDOCYTIC_2	127	130	PF00928	0.624
TRG_ENDOCYTIC_2	193	196	PF00928	0.504
TRG_ER_diArg_1	184	187	PF00400	0.572
TRG_ER_diArg_1	213	216	PF00400	0.645
TRG_ER_diArg_1	8	11	PF00400	0.597

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0F4	Leptomonas seymouri	50%	100%
A4HVE3	Leishmania infantum	89%	100%