Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QGD5_LEIMA

TriTrypDb:

LmjF.13.0190 , LMJLV39_130006900 , LMJSD75_130007000

Length:

248

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGD5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGD5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	120	122	PF00675	0.671
CLV_NRD_NRD_1	134	136	PF00675	0.577
CLV_NRD_NRD_1	208	210	PF00675	0.607
CLV_NRD_NRD_1	8	10	PF00675	0.724
CLV_PCSK_KEX2_1	27	29	PF00082	0.693
CLV_PCSK_KEX2_1	66	68	PF00082	0.566
CLV_PCSK_KEX2_1	8	10	PF00082	0.724
CLV_PCSK_PC1ET2_1	27	29	PF00082	0.693
CLV_PCSK_PC1ET2_1	66	68	PF00082	0.626
CLV_PCSK_SKI1_1	121	125	PF00082	0.770
CLV_PCSK_SKI1_1	63	67	PF00082	0.651
CLV_PCSK_SKI1_1	76	80	PF00082	0.534
DEG_Kelch_Keap1_1	168	173	PF01344	0.654
DEG_Nend_Nbox_1	1	3	PF02207	0.690
DOC_CKS1_1	54	59	PF01111	0.599
DOC_CKS1_1	82	87	PF01111	0.666
DOC_USP7_MATH_1	15	19	PF00917	0.782
DOC_USP7_MATH_1	156	160	PF00917	0.752
DOC_USP7_UBL2_3	59	63	PF12436	0.626
DOC_WW_Pin1_4	152	157	PF00397	0.778
DOC_WW_Pin1_4	191	196	PF00397	0.622
DOC_WW_Pin1_4	42	47	PF00397	0.576
DOC_WW_Pin1_4	53	58	PF00397	0.550
DOC_WW_Pin1_4	81	86	PF00397	0.700
LIG_14-3-3_CanoR_1	121	127	PF00244	0.667
LIG_14-3-3_CanoR_1	28	36	PF00244	0.642
LIG_14-3-3_CanoR_1	51	57	PF00244	0.669
LIG_14-3-3_CanoR_1	8	16	PF00244	0.720
LIG_APCC_ABBA_1	230	235	PF00400	0.600
LIG_DCNL_PONY_1	1	4	PF03556	0.688
LIG_EVH1_1	81	85	PF00568	0.653
LIG_FHA_1	203	209	PF00498	0.551
LIG_LIR_Gen_1	159	167	PF02991	0.693
LIG_LIR_Nem_3	125	129	PF02991	0.640
LIG_LIR_Nem_3	130	134	PF02991	0.553
LIG_LIR_Nem_3	154	160	PF02991	0.719
LIG_LIR_Nem_3	64	68	PF02991	0.525
LIG_PTB_Apo_2	93	100	PF02174	0.515
LIG_SH2_CRK	201	205	PF00017	0.544
LIG_SH2_GRB2like	160	163	PF00017	0.693
LIG_SH2_NCK_1	160	164	PF00017	0.692
LIG_SH2_NCK_1	69	73	PF00017	0.669
LIG_SH2_STAT5	236	239	PF00017	0.525
LIG_SH2_STAT5	24	27	PF00017	0.729
LIG_SH2_STAT5	245	248	PF00017	0.601
LIG_SH2_STAT5	36	39	PF00017	0.816
LIG_SH3_3	51	57	PF00018	0.741
LIG_SH3_3	79	85	PF00018	0.644
MOD_CDK_SPxK_1	53	59	PF00069	0.665
MOD_CK1_1	149	155	PF00069	0.807
MOD_CK1_1	171	177	PF00069	0.759
MOD_CK1_1	45	51	PF00069	0.637
MOD_CK1_1	55	61	PF00069	0.634
MOD_CK2_1	105	111	PF00069	0.496
MOD_CK2_1	158	164	PF00069	0.691
MOD_CK2_1	167	173	PF00069	0.714
MOD_CK2_1	190	196	PF00069	0.655
MOD_GlcNHglycan	17	20	PF01048	0.748
MOD_GlcNHglycan	170	173	PF01048	0.756
MOD_GlcNHglycan	220	223	PF01048	0.594
MOD_GlcNHglycan	31	34	PF01048	0.533
MOD_GlcNHglycan	47	50	PF01048	0.713
MOD_GSK3_1	145	152	PF00069	0.726
MOD_GSK3_1	167	174	PF00069	0.695
MOD_GSK3_1	72	79	PF00069	0.563
MOD_N-GLC_1	218	223	PF02516	0.576
MOD_N-GLC_1	29	34	PF02516	0.732
MOD_NEK2_1	167	172	PF00069	0.688
MOD_NEK2_1	2	7	PF00069	0.697
MOD_NEK2_2	236	241	PF00069	0.409
MOD_OFUCOSY	103	109	PF10250	0.656
MOD_PKA_1	135	141	PF00069	0.666
MOD_PKA_2	7	13	PF00069	0.729
MOD_PKB_1	74	82	PF00069	0.663
MOD_Plk_1	76	82	PF00069	0.593
MOD_Plk_4	2	8	PF00069	0.696
MOD_ProDKin_1	152	158	PF00069	0.776
MOD_ProDKin_1	191	197	PF00069	0.615
MOD_ProDKin_1	42	48	PF00069	0.579
MOD_ProDKin_1	53	59	PF00069	0.549
MOD_ProDKin_1	81	87	PF00069	0.703
MOD_SUMO_rev_2	114	124	PF00179	0.637
MOD_SUMO_rev_2	58	68	PF00179	0.632
TRG_ENDOCYTIC_2	126	129	PF00928	0.639
TRG_ENDOCYTIC_2	160	163	PF00928	0.693
TRG_ENDOCYTIC_2	201	204	PF00928	0.491
TRG_ENDOCYTIC_2	69	72	PF00928	0.614
TRG_ER_diArg_1	7	9	PF00400	0.734
TRG_Pf-PMV_PEXEL_1	93	98	PF00026	0.574

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZ69	Leptomonas seymouri	57%	100%
A0A3Q8I9J1	Leishmania donovani	94%	100%
A4H726	Leishmania braziliensis	79%	69%
A4HVF5	Leishmania infantum	93%	100%
E9AP53	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%