Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QGA1_LEIMA

TriTrypDb:

LmjF.13.0530 , LMJLV39_130009300 , LMJSD75_130009400

Length:

996

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QGA1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGA1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	216	220	PF00656	0.504
CLV_C14_Caspase3-7	583	587	PF00656	0.460
CLV_C14_Caspase3-7	865	869	PF00656	0.579
CLV_C14_Caspase3-7	949	953	PF00656	0.571
CLV_C14_Caspase3-7	984	988	PF00656	0.583
CLV_NRD_NRD_1	225	227	PF00675	0.433
CLV_NRD_NRD_1	3	5	PF00675	0.510
CLV_NRD_NRD_1	353	355	PF00675	0.507
CLV_NRD_NRD_1	372	374	PF00675	0.377
CLV_NRD_NRD_1	466	468	PF00675	0.490
CLV_NRD_NRD_1	563	565	PF00675	0.476
CLV_NRD_NRD_1	570	572	PF00675	0.425
CLV_NRD_NRD_1	637	639	PF00675	0.464
CLV_NRD_NRD_1	642	644	PF00675	0.460
CLV_NRD_NRD_1	645	647	PF00675	0.468
CLV_PCSK_FUR_1	370	374	PF00082	0.462
CLV_PCSK_FUR_1	635	639	PF00082	0.497
CLV_PCSK_FUR_1	643	647	PF00082	0.517
CLV_PCSK_KEX2_1	200	202	PF00082	0.529
CLV_PCSK_KEX2_1	225	227	PF00082	0.433
CLV_PCSK_KEX2_1	353	355	PF00082	0.458
CLV_PCSK_KEX2_1	372	374	PF00082	0.444
CLV_PCSK_KEX2_1	466	468	PF00082	0.602
CLV_PCSK_KEX2_1	562	564	PF00082	0.486
CLV_PCSK_KEX2_1	570	572	PF00082	0.423
CLV_PCSK_KEX2_1	637	639	PF00082	0.461
CLV_PCSK_KEX2_1	642	644	PF00082	0.459
CLV_PCSK_KEX2_1	645	647	PF00082	0.472
CLV_PCSK_KEX2_1	65	67	PF00082	0.489
CLV_PCSK_KEX2_1	70	72	PF00082	0.479
CLV_PCSK_KEX2_1	739	741	PF00082	0.673
CLV_PCSK_PC1ET2_1	200	202	PF00082	0.529
CLV_PCSK_PC1ET2_1	562	564	PF00082	0.494
CLV_PCSK_PC1ET2_1	65	67	PF00082	0.419
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.411
CLV_PCSK_PC1ET2_1	739	741	PF00082	0.673
CLV_PCSK_PC7_1	559	565	PF00082	0.508
CLV_PCSK_PC7_1	638	644	PF00082	0.485
CLV_PCSK_PC7_1	66	72	PF00082	0.409
CLV_PCSK_SKI1_1	114	118	PF00082	0.492
CLV_PCSK_SKI1_1	127	131	PF00082	0.534
CLV_PCSK_SKI1_1	143	147	PF00082	0.445
CLV_PCSK_SKI1_1	240	244	PF00082	0.446
CLV_PCSK_SKI1_1	261	265	PF00082	0.465
CLV_PCSK_SKI1_1	296	300	PF00082	0.466
CLV_PCSK_SKI1_1	317	321	PF00082	0.461
CLV_PCSK_SKI1_1	380	384	PF00082	0.515
CLV_PCSK_SKI1_1	467	471	PF00082	0.501
CLV_PCSK_SKI1_1	564	568	PF00082	0.461
CLV_PCSK_SKI1_1	822	826	PF00082	0.637
CLV_PCSK_SKI1_1	83	87	PF00082	0.516
DEG_APCC_DBOX_1	142	150	PF00400	0.439
DEG_Nend_UBRbox_2	1	3	PF02207	0.403
DEG_SPOP_SBC_1	213	217	PF00917	0.473
DEG_SPOP_SBC_1	519	523	PF00917	0.571
DEG_SPOP_SBC_1	723	727	PF00917	0.661
DEG_SPOP_SBC_1	823	827	PF00917	0.635
DEG_SPOP_SBC_1	887	891	PF00917	0.609
DEG_SPOP_SBC_1	989	993	PF00917	0.522
DOC_CKS1_1	745	750	PF01111	0.622
DOC_CYCLIN_RxL_1	559	569	PF00134	0.459
DOC_MAPK_gen_1	122	132	PF00069	0.506
DOC_MAPK_gen_1	837	847	PF00069	0.621
DOC_MAPK_MEF2A_6	125	134	PF00069	0.505
DOC_MAPK_MEF2A_6	610	619	PF00069	0.534
DOC_MAPK_NFAT4_5	127	135	PF00069	0.465
DOC_PP2B_LxvP_1	516	519	PF13499	0.580
DOC_PP2B_LxvP_1	667	670	PF13499	0.591
DOC_USP7_MATH_1	148	152	PF00917	0.631
DOC_USP7_MATH_1	171	175	PF00917	0.661
DOC_USP7_MATH_1	176	180	PF00917	0.714
DOC_USP7_MATH_1	220	224	PF00917	0.475
DOC_USP7_MATH_1	392	396	PF00917	0.585
DOC_USP7_MATH_1	425	429	PF00917	0.522
DOC_USP7_MATH_1	512	516	PF00917	0.538
DOC_USP7_MATH_1	519	523	PF00917	0.591
DOC_USP7_MATH_1	721	725	PF00917	0.668
DOC_USP7_MATH_1	758	762	PF00917	0.714
DOC_USP7_MATH_1	768	772	PF00917	0.594
DOC_USP7_MATH_1	79	83	PF00917	0.482
DOC_USP7_MATH_1	795	799	PF00917	0.629
DOC_USP7_MATH_1	860	864	PF00917	0.650
DOC_USP7_MATH_1	887	891	PF00917	0.643
DOC_USP7_MATH_1	893	897	PF00917	0.583
DOC_USP7_MATH_1	933	937	PF00917	0.603
DOC_USP7_MATH_1	959	963	PF00917	0.640
DOC_USP7_MATH_1	989	993	PF00917	0.488
DOC_WW_Pin1_4	521	526	PF00397	0.598
DOC_WW_Pin1_4	665	670	PF00397	0.600
DOC_WW_Pin1_4	725	730	PF00397	0.664
DOC_WW_Pin1_4	744	749	PF00397	0.536
DOC_WW_Pin1_4	751	756	PF00397	0.622
DOC_WW_Pin1_4	789	794	PF00397	0.648
DOC_WW_Pin1_4	907	912	PF00397	0.641
DOC_WW_Pin1_4	969	974	PF00397	0.547
DOC_WW_Pin1_4	985	990	PF00397	0.707
LIG_14-3-3_CanoR_1	114	121	PF00244	0.493
LIG_14-3-3_CanoR_1	301	305	PF00244	0.621
LIG_14-3-3_CanoR_1	431	440	PF00244	0.517
LIG_14-3-3_CanoR_1	442	446	PF00244	0.656
LIG_14-3-3_CanoR_1	563	567	PF00244	0.530
LIG_14-3-3_CanoR_1	570	578	PF00244	0.475
LIG_14-3-3_CanoR_1	610	617	PF00244	0.578
LIG_14-3-3_CanoR_1	71	77	PF00244	0.445
LIG_14-3-3_CanoR_1	753	762	PF00244	0.594
LIG_14-3-3_CanoR_1	802	809	PF00244	0.643
LIG_14-3-3_CanoR_1	840	847	PF00244	0.650
LIG_14-3-3_CanoR_1	920	925	PF00244	0.716
LIG_14-3-3_CanoR_1	947	954	PF00244	0.746
LIG_Actin_WH2_2	187	205	PF00022	0.509
LIG_Actin_WH2_2	401	419	PF00022	0.614
LIG_APCC_ABBA_1	134	139	PF00400	0.512
LIG_BRCT_BRCA1_1	732	736	PF00533	0.675
LIG_BRCT_BRCA1_1	961	965	PF00533	0.724
LIG_BRCT_BRCA1_1	990	994	PF00533	0.639
LIG_CaM_IQ_9	288	303	PF13499	0.394
LIG_CaM_IQ_9	549	565	PF13499	0.516
LIG_Clathr_ClatBox_1	41	45	PF01394	0.475
LIG_deltaCOP1_diTrp_1	974	979	PF00928	0.561
LIG_DLG_GKlike_1	920	927	PF00625	0.625
LIG_FHA_1	148	154	PF00498	0.535
LIG_FHA_1	213	219	PF00498	0.448
LIG_FHA_1	297	303	PF00498	0.454
LIG_FHA_1	363	369	PF00498	0.594
LIG_FHA_1	37	43	PF00498	0.477
LIG_FHA_1	408	414	PF00498	0.489
LIG_FHA_1	418	424	PF00498	0.441
LIG_FHA_1	432	438	PF00498	0.430
LIG_FHA_1	44	50	PF00498	0.396
LIG_FHA_1	468	474	PF00498	0.484
LIG_FHA_1	543	549	PF00498	0.663
LIG_FHA_1	649	655	PF00498	0.585
LIG_FHA_1	674	680	PF00498	0.788
LIG_FHA_1	685	691	PF00498	0.685
LIG_FHA_1	833	839	PF00498	0.620
LIG_FHA_2	118	124	PF00498	0.508
LIG_FHA_2	324	330	PF00498	0.473
LIG_FHA_2	51	57	PF00498	0.620
LIG_FHA_2	927	933	PF00498	0.725
LIG_FHA_2	940	946	PF00498	0.606
LIG_LIR_Apic_2	534	540	PF02991	0.583
LIG_LIR_Gen_1	11	21	PF02991	0.502
LIG_LIR_Gen_1	702	708	PF02991	0.735
LIG_LIR_Gen_1	939	946	PF02991	0.680
LIG_LIR_Gen_1	974	983	PF02991	0.604
LIG_LIR_Nem_3	11	16	PF02991	0.504
LIG_LIR_Nem_3	702	706	PF02991	0.628
LIG_LIR_Nem_3	939	943	PF02991	0.681
LIG_LIR_Nem_3	974	979	PF02991	0.599
LIG_LYPXL_SIV_4	136	144	PF13949	0.518
LIG_NRBOX	290	296	PF00104	0.480
LIG_NRBOX	662	668	PF00104	0.595
LIG_PCNA_PIPBox_1	672	681	PF02747	0.615
LIG_SH2_CRK	537	541	PF00017	0.571
LIG_SH2_NCK_1	137	141	PF00017	0.510
LIG_SH2_NCK_1	537	541	PF00017	0.571
LIG_SH2_STAP1	84	88	PF00017	0.482
LIG_SH2_STAT5	197	200	PF00017	0.526
LIG_SH2_STAT5	212	215	PF00017	0.503
LIG_SH2_STAT5	532	535	PF00017	0.611
LIG_SH2_STAT5	72	75	PF00017	0.549
LIG_SH3_2	745	750	PF14604	0.622
LIG_SH3_3	150	156	PF00018	0.579
LIG_SH3_3	652	658	PF00018	0.494
LIG_SH3_3	742	748	PF00018	0.653
LIG_SH3_3	932	938	PF00018	0.537
LIG_SUMO_SIM_anti_2	977	984	PF11976	0.567
LIG_SUMO_SIM_par_1	37	47	PF11976	0.491
LIG_SUMO_SIM_par_1	403	410	PF11976	0.503
LIG_TRAF2_1	312	315	PF00917	0.490
LIG_TRAF2_1	670	673	PF00917	0.595
LIG_TRAF2_1	942	945	PF00917	0.661
LIG_UBA3_1	548	555	PF00899	0.491
MOD_CDK_SPxK_1	744	750	PF00069	0.622
MOD_CK1_1	163	169	PF00069	0.635
MOD_CK1_1	391	397	PF00069	0.615
MOD_CK1_1	472	478	PF00069	0.501
MOD_CK1_1	521	527	PF00069	0.598
MOD_CK1_1	665	671	PF00069	0.602
MOD_CK1_1	699	705	PF00069	0.623
MOD_CK1_1	724	730	PF00069	0.612
MOD_CK1_1	761	767	PF00069	0.628
MOD_CK1_1	789	795	PF00069	0.672
MOD_CK1_1	807	813	PF00069	0.668
MOD_CK1_1	863	869	PF00069	0.691
MOD_CK1_1	931	937	PF00069	0.618
MOD_CK1_1	988	994	PF00069	0.617
MOD_CK2_1	117	123	PF00069	0.465
MOD_CK2_1	171	177	PF00069	0.643
MOD_CK2_1	323	329	PF00069	0.563
MOD_CK2_1	360	366	PF00069	0.524
MOD_CK2_1	50	56	PF00069	0.527
MOD_CK2_1	576	582	PF00069	0.536
MOD_CK2_1	716	722	PF00069	0.642
MOD_CK2_1	926	932	PF00069	0.727
MOD_CK2_1	938	944	PF00069	0.596
MOD_GlcNHglycan	174	177	PF01048	0.716
MOD_GlcNHglycan	184	187	PF01048	0.557
MOD_GlcNHglycan	373	376	PF01048	0.501
MOD_GlcNHglycan	390	393	PF01048	0.690
MOD_GlcNHglycan	420	423	PF01048	0.609
MOD_GlcNHglycan	599	602	PF01048	0.617
MOD_GlcNHglycan	719	722	PF01048	0.676
MOD_GlcNHglycan	770	773	PF01048	0.635
MOD_GlcNHglycan	806	809	PF01048	0.650
MOD_GlcNHglycan	841	844	PF01048	0.675
MOD_GlcNHglycan	862	865	PF01048	0.755
MOD_GlcNHglycan	949	952	PF01048	0.744
MOD_GlcNHglycan	961	964	PF01048	0.799
MOD_GSK3_1	158	165	PF00069	0.632
MOD_GSK3_1	172	179	PF00069	0.680
MOD_GSK3_1	296	303	PF00069	0.476
MOD_GSK3_1	388	395	PF00069	0.677
MOD_GSK3_1	431	438	PF00069	0.601
MOD_GSK3_1	468	475	PF00069	0.475
MOD_GSK3_1	520	527	PF00069	0.537
MOD_GSK3_1	562	569	PF00069	0.513
MOD_GSK3_1	597	604	PF00069	0.548
MOD_GSK3_1	695	702	PF00069	0.720
MOD_GSK3_1	712	719	PF00069	0.593
MOD_GSK3_1	721	728	PF00069	0.665
MOD_GSK3_1	754	761	PF00069	0.623
MOD_GSK3_1	763	770	PF00069	0.600
MOD_GSK3_1	782	789	PF00069	0.520
MOD_GSK3_1	839	846	PF00069	0.786
MOD_GSK3_1	877	884	PF00069	0.622
MOD_GSK3_1	961	968	PF00069	0.668
MOD_GSK3_1	981	988	PF00069	0.514
MOD_GSK3_1	989	996	PF00069	0.627
MOD_N-GLC_1	699	704	PF02516	0.628
MOD_N-GLC_1	965	970	PF02516	0.613
MOD_NEK2_1	26	31	PF00069	0.467
MOD_NEK2_1	44	49	PF00069	0.382
MOD_NEK2_1	441	446	PF00069	0.614
MOD_NEK2_1	469	474	PF00069	0.459
MOD_NEK2_1	481	486	PF00069	0.527
MOD_NEK2_1	498	503	PF00069	0.476
MOD_NEK2_1	566	571	PF00069	0.500
MOD_NEK2_1	650	655	PF00069	0.620
MOD_NEK2_1	662	667	PF00069	0.584
MOD_NEK2_1	824	829	PF00069	0.640
MOD_NEK2_1	965	970	PF00069	0.710
MOD_NEK2_2	220	225	PF00069	0.502
MOD_NEK2_2	712	717	PF00069	0.627
MOD_PIKK_1	303	309	PF00454	0.494
MOD_PIKK_1	392	398	PF00454	0.582
MOD_PIKK_1	601	607	PF00454	0.506
MOD_PIKK_1	609	615	PF00454	0.488
MOD_PIKK_1	763	769	PF00454	0.777
MOD_PIKK_1	795	801	PF00454	0.665
MOD_PIKK_1	824	830	PF00454	0.632
MOD_PIKK_1	933	939	PF00454	0.644
MOD_PKA_1	562	568	PF00069	0.480
MOD_PKA_1	70	76	PF00069	0.402
MOD_PKA_1	717	723	PF00069	0.675
MOD_PKA_2	202	208	PF00069	0.495
MOD_PKA_2	300	306	PF00069	0.451
MOD_PKA_2	307	313	PF00069	0.413
MOD_PKA_2	371	377	PF00069	0.532
MOD_PKA_2	441	447	PF00069	0.501
MOD_PKA_2	562	568	PF00069	0.548
MOD_PKA_2	609	615	PF00069	0.519
MOD_PKA_2	641	647	PF00069	0.523
MOD_PKA_2	70	76	PF00069	0.480
MOD_PKA_2	839	845	PF00069	0.653
MOD_PKA_2	860	866	PF00069	0.764
MOD_PKA_2	946	952	PF00069	0.752
MOD_PKB_1	415	423	PF00069	0.443
MOD_PKB_1	918	926	PF00069	0.535
MOD_Plk_1	117	123	PF00069	0.462
MOD_Plk_1	26	32	PF00069	0.623
MOD_Plk_1	360	366	PF00069	0.447
MOD_Plk_1	435	441	PF00069	0.524
MOD_Plk_1	44	50	PF00069	0.396
MOD_Plk_1	699	705	PF00069	0.625
MOD_Plk_1	833	839	PF00069	0.654
MOD_Plk_1	843	849	PF00069	0.555
MOD_Plk_1	881	887	PF00069	0.644
MOD_Plk_2-3	360	366	PF00069	0.521
MOD_Plk_2-3	94	100	PF00069	0.430
MOD_Plk_4	323	329	PF00069	0.475
MOD_Plk_4	44	50	PF00069	0.631
MOD_Plk_4	453	459	PF00069	0.625
MOD_Plk_4	512	518	PF00069	0.551
MOD_Plk_4	662	668	PF00069	0.618
MOD_ProDKin_1	521	527	PF00069	0.601
MOD_ProDKin_1	665	671	PF00069	0.602
MOD_ProDKin_1	725	731	PF00069	0.660
MOD_ProDKin_1	744	750	PF00069	0.538
MOD_ProDKin_1	751	757	PF00069	0.622
MOD_ProDKin_1	789	795	PF00069	0.647
MOD_ProDKin_1	907	913	PF00069	0.642
MOD_ProDKin_1	969	975	PF00069	0.544
MOD_ProDKin_1	985	991	PF00069	0.709
TRG_DiLeu_BaEn_1	126	131	PF01217	0.514
TRG_DiLeu_BaEn_1	315	320	PF01217	0.495
TRG_DiLeu_BaEn_1	37	42	PF01217	0.479
TRG_DiLeu_BaEn_1	45	50	PF01217	0.473
TRG_DiLeu_BaEn_4	37	43	PF01217	0.465
TRG_DiLeu_BaEn_4	403	409	PF01217	0.534
TRG_DiLeu_BaLyEn_6	342	347	PF01217	0.501
TRG_ENDOCYTIC_2	13	16	PF00928	0.462
TRG_ENDOCYTIC_2	254	257	PF00928	0.494
TRG_ER_diArg_1	224	226	PF00400	0.439
TRG_ER_diArg_1	353	356	PF00400	0.513
TRG_ER_diArg_1	370	373	PF00400	0.399
TRG_ER_diArg_1	465	467	PF00400	0.502
TRG_ER_diArg_1	556	559	PF00400	0.493
TRG_ER_diArg_1	637	639	PF00400	0.539
TRG_ER_diArg_1	642	645	PF00400	0.498
TRG_NES_CRM1_1	106	118	PF08389	0.415
TRG_NES_CRM1_1	11	24	PF08389	0.407
TRG_NES_CRM1_1	40	54	PF08389	0.477
TRG_Pf-PMV_PEXEL_1	122	126	PF00026	0.474
TRG_Pf-PMV_PEXEL_1	317	321	PF00026	0.461
TRG_Pf-PMV_PEXEL_1	345	349	PF00026	0.469
TRG_Pf-PMV_PEXEL_1	645	649	PF00026	0.511

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMF5	Leptomonas seymouri	46%	82%
A0A3S7WSE4	Leishmania donovani	92%	81%
A0A422NQU2	Trypanosoma rangeli	27%	99%
A4H742	Leishmania braziliensis	75%	100%
A4HVI2	Leishmania infantum	92%	81%
E9AP77	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	81%