Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QGA0_LEIMA

TriTrypDb:

LmjF.13.0540 , LMJLV39_130009400 , LMJSD75_130009500

Length:

198

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	2
GO:0016020	membrane	2	6
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	8

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Expansion

Sequence features

Q4QGA0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QGA0

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	180	182	PF00675	0.519
CLV_NRD_NRD_1	54	56	PF00675	0.432
CLV_PCSK_FUR_1	45	49	PF00082	0.457
CLV_PCSK_KEX2_1	178	180	PF00082	0.457
CLV_PCSK_KEX2_1	47	49	PF00082	0.436
CLV_PCSK_KEX2_1	53	55	PF00082	0.417
CLV_PCSK_PC1ET2_1	178	180	PF00082	0.452
CLV_PCSK_PC1ET2_1	47	49	PF00082	0.434
CLV_PCSK_SKI1_1	128	132	PF00082	0.437
CLV_PCSK_SKI1_1	33	37	PF00082	0.456

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE47	Leptomonas seymouri	76%	100%
A0A0S4J5J9	Bodo saltans	40%	100%
A0A1X0NNT8	Trypanosomatidae	44%	96%
A0A3Q8IHY4	Leishmania donovani	96%	100%
A0A3R7MTA4	Trypanosoma rangeli	46%	100%
A4H743	Leishmania braziliensis	84%	100%
A4HVI3	Leishmania infantum	96%	100%
D0A6S6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
E9AP78	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
V5DBH6	Trypanosoma cruzi	46%	100%

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