LeishMANIAdb
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C2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
C2 domain-containing protein
Gene product:
C2 domain containing protein, putative
Species:
Leishmania major
UniProt:
Q4QG78_LEIMA
TriTrypDb:
LmjF.13.0760 , LMJLV39_130011600 * , LMJSD75_130011700 *
Length:
2063

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
TermNameLevelCount
GO:0005886 plasma membrane 3 2
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2
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Expansion

Sequence features

Q4QG78
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 2
GO:0006886 intracellular protein transport 4 2
GO:0008104 protein localization 4 2
GO:0009987 cellular process 1 2
GO:0010638 positive regulation of organelle organization 6 2
GO:0010827 regulation of glucose transmembrane transport 5 2
GO:0010828 positive regulation of glucose transmembrane transport 6 2
GO:0015031 protein transport 4 2
GO:0031338 regulation of vesicle fusion 5 2
GO:0031340 positive regulation of vesicle fusion 5 2
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Molecular functions
TermNameLevelCount
GO:0005488 binding 1 6
GO:0005509 calcium ion binding 5 2
GO:0005543 phospholipid binding 3 6
GO:0005544 calcium-dependent phospholipid binding 4 6
GO:0008289 lipid binding 2 6
GO:0043167 ion binding 2 2
GO:0043169 cation binding 3 2
GO:0046872 metal ion binding 4 2
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1191 1195 PF00656 0.709
CLV_C14_Caspase3-7 1509 1513 PF00656 0.462
CLV_C14_Caspase3-7 1805 1809 PF00656 0.753
CLV_C14_Caspase3-7 1861 1865 PF00656 0.480
CLV_C14_Caspase3-7 1952 1956 PF00656 0.610
CLV_C14_Caspase3-7 2051 2055 PF00656 0.654
CLV_C14_Caspase3-7 248 252 PF00656 0.579
CLV_C14_Caspase3-7 441 445 PF00656 0.582
CLV_C14_Caspase3-7 679 683 PF00656 0.695
CLV_C14_Caspase3-7 747 751 PF00656 0.411
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WSG4 Leishmania donovani 94% 100%
A4H765 Leishmania braziliensis 74% 100%
A4HVK4 Leishmania infantum 94% 100%
E9APA0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS