Glycosyltransferase family-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glycosyltransferase family-like protein

Species:

Leishmania major

UniProt:

Q4QG61_LEIMA

TriTrypDb:

LmjF.13.0930 , LMJLV39_130013400 , LMJSD75_130013500

Length:

275

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 21
NetGPI	no	yes: 0, no: 21

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	3
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0043233	organelle lumen	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	3

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Expansion

Sequence features

Q4QG61

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QG61

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	22
GO:0016740	transferase activity	2	22

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	256	260	PF00656	0.429
CLV_C14_Caspase3-7	53	57	PF00656	0.259
CLV_NRD_NRD_1	22	24	PF00675	0.457
CLV_NRD_NRD_1	262	264	PF00675	0.529
CLV_NRD_NRD_1	6	8	PF00675	0.527
CLV_PCSK_KEX2_1	22	24	PF00082	0.455
CLV_PCSK_KEX2_1	262	264	PF00082	0.529
CLV_PCSK_KEX2_1	35	37	PF00082	0.458
CLV_PCSK_KEX2_1	6	8	PF00082	0.527
CLV_PCSK_PC1ET2_1	35	37	PF00082	0.513

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P896	Leptomonas seymouri	79%	100%
A0A0N1PCD6	Leptomonas seymouri	33%	95%
A0A0S4IK22	Bodo saltans	63%	98%
A0A1X0NN04	Trypanosomatidae	67%	100%
A0A1X0P3F1	Trypanosomatidae	39%	80%
A0A3Q8I9N9	Leishmania donovani	96%	100%
A0A3R7K9Z6	Trypanosoma rangeli	36%	91%
A0A3R7MES7	Trypanosoma rangeli	71%	100%
A0A3S7XB94	Leishmania donovani	32%	96%
A4H781	Leishmania braziliensis	91%	100%

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