LeishMANIAdb
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Putative proteasome regulatory ATPase subunit 2

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative proteasome regulatory ATPase subunit 2
Gene product:
proteasome regulatory ATPase subunit 2, putative
Species:
Leishmania major
UniProt:
Q4QG45_LEIMA
TriTrypDb:
LmjF.13.1090 , LMJLV39_130015100 , LMJSD75_130015100
Length:
438

Annotations

LeishMANIAdb annotations

A large and likely artifical grouping of protease domain carrying proteins related to proteasomal proteases. Only a tiny subgroup (the AFG3-related mitochondrail proteins) seem to have a TM segment.. Localization: Cytoplasmic (by homology) / Mitochondrial (by homology)

Annotations by Jardim et al.

Proteasome, proteasome regulatory ATPase subunit 2

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) yes yes: 6
Forrest at al. (procyclic) yes yes: 6
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. yes yes: 18
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005654 nucleoplasm 2 2
GO:0005737 cytoplasm 2 12
GO:0008540 proteasome regulatory particle, base subcomplex 2 2
GO:0032991 protein-containing complex 1 12
GO:0110165 cellular anatomical entity 1 12
GO:0000502 proteasome complex 3 10
GO:0005634 nucleus 5 9
GO:0043226 organelle 2 9
GO:0043227 membrane-bounded organelle 3 9
GO:0043229 intracellular organelle 3 9
GO:0043231 intracellular membrane-bounded organelle 4 9
GO:0140535 intracellular protein-containing complex 2 10
GO:1902494 catalytic complex 2 10
GO:1905368 peptidase complex 3 10
GO:1905369 endopeptidase complex 4 10

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

Q4QG45
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QG45

Function

Biological processes
Term Name Level Count
GO:0006508 proteolysis 4 2
GO:0006511 ubiquitin-dependent protein catabolic process 7 2
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009056 catabolic process 2 12
GO:0009057 macromolecule catabolic process 4 12
GO:0009987 cellular process 1 2
GO:0010498 proteasomal protein catabolic process 5 2
GO:0019538 protein metabolic process 3 12
GO:0019941 modification-dependent protein catabolic process 6 2
GO:0030163 protein catabolic process 4 12
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 6 2
GO:0043170 macromolecule metabolic process 3 12
GO:0043632 modification-dependent macromolecule catabolic process 5 2
GO:0044237 cellular metabolic process 2 2
GO:0044238 primary metabolic process 2 12
GO:0044248 cellular catabolic process 3 2
GO:0044260 obsolete cellular macromolecule metabolic process 3 2
GO:0044265 obsolete cellular macromolecule catabolic process 4 2
GO:0051603 proteolysis involved in protein catabolic process 5 2
GO:0071704 organic substance metabolic process 2 12
GO:1901564 organonitrogen compound metabolic process 3 12
GO:1901565 organonitrogen compound catabolic process 4 12
GO:1901575 organic substance catabolic process 3 12
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0016462 pyrophosphatase activity 5 12
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 12
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 12
GO:0016887 ATP hydrolysis activity 7 12
GO:0017076 purine nucleotide binding 4 12
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 12
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0036402 proteasome-activating activity 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0140657 ATP-dependent activity 1 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 283 287 PF00656 0.247
CLV_C14_Caspase3-7 312 316 PF00656 0.247
CLV_NRD_NRD_1 27 29 PF00675 0.637
CLV_NRD_NRD_1 346 348 PF00675 0.247
CLV_NRD_NRD_1 360 362 PF00675 0.358
CLV_NRD_NRD_1 408 410 PF00675 0.262
CLV_NRD_NRD_1 426 428 PF00675 0.398
CLV_NRD_NRD_1 51 53 PF00675 0.504
CLV_PCSK_FUR_1 406 410 PF00082 0.262
CLV_PCSK_KEX2_1 27 29 PF00082 0.647
CLV_PCSK_KEX2_1 291 293 PF00082 0.247
CLV_PCSK_KEX2_1 31 33 PF00082 0.680
CLV_PCSK_KEX2_1 359 361 PF00082 0.503
CLV_PCSK_KEX2_1 408 410 PF00082 0.262
CLV_PCSK_KEX2_1 96 98 PF00082 0.542
CLV_PCSK_PC1ET2_1 27 29 PF00082 0.647
CLV_PCSK_PC1ET2_1 291 293 PF00082 0.247
CLV_PCSK_PC1ET2_1 31 33 PF00082 0.680
CLV_PCSK_PC1ET2_1 359 361 PF00082 0.503
CLV_PCSK_PC1ET2_1 96 98 PF00082 0.542
CLV_PCSK_SKI1_1 230 234 PF00082 0.247
CLV_PCSK_SKI1_1 266 270 PF00082 0.247
CLV_PCSK_SKI1_1 305 309 PF00082 0.247
CLV_PCSK_SKI1_1 360 364 PF00082 0.392
CLV_PCSK_SKI1_1 408 412 PF00082 0.262
DEG_APCC_DBOX_1 304 312 PF00400 0.247
DEG_APCC_KENBOX_2 420 424 PF00400 0.355
DOC_CYCLIN_RxL_1 263 273 PF00134 0.262
DOC_MAPK_FxFP_2 351 354 PF00069 0.344
DOC_MAPK_gen_1 341 351 PF00069 0.247
DOC_MAPK_gen_1 55 65 PF00069 0.359
DOC_MAPK_MEF2A_6 162 171 PF00069 0.546
DOC_MAPK_RevD_3 277 292 PF00069 0.247
DOC_PP1_RVXF_1 345 352 PF00149 0.247
DOC_PP4_FxxP_1 351 354 PF00568 0.344
DOC_USP7_MATH_1 120 124 PF00917 0.413
DOC_USP7_MATH_1 132 136 PF00917 0.413
DOC_USP7_MATH_1 167 171 PF00917 0.403
DOC_USP7_UBL2_3 27 31 PF12436 0.687
DOC_WW_Pin1_4 101 106 PF00397 0.482
DOC_WW_Pin1_4 273 278 PF00397 0.247
LIG_14-3-3_CanoR_1 240 246 PF00244 0.400
LIG_14-3-3_CanoR_1 369 373 PF00244 0.352
LIG_BIR_III_4 286 290 PF00653 0.247
LIG_BRCT_BRCA1_1 241 245 PF00533 0.273
LIG_FHA_1 298 304 PF00498 0.393
LIG_FHA_1 327 333 PF00498 0.262
LIG_FHA_2 102 108 PF00498 0.403
LIG_FHA_2 179 185 PF00498 0.380
LIG_FHA_2 304 310 PF00498 0.247
LIG_LIR_Apic_2 127 132 PF02991 0.454
LIG_LIR_Apic_2 15 20 PF02991 0.556
LIG_LIR_Apic_2 350 354 PF02991 0.247
LIG_LIR_Gen_1 179 188 PF02991 0.395
LIG_LIR_Gen_1 207 217 PF02991 0.380
LIG_LIR_Gen_1 242 253 PF02991 0.247
LIG_LIR_Gen_1 431 438 PF02991 0.520
LIG_LIR_Gen_1 61 70 PF02991 0.359
LIG_LIR_Nem_3 127 133 PF02991 0.508
LIG_LIR_Nem_3 179 185 PF02991 0.406
LIG_LIR_Nem_3 207 212 PF02991 0.389
LIG_LIR_Nem_3 242 248 PF02991 0.256
LIG_LIR_Nem_3 431 436 PF02991 0.509
LIG_LIR_Nem_3 61 65 PF02991 0.365
LIG_PCNA_yPIPBox_3 153 161 PF02747 0.437
LIG_PCNA_yPIPBox_3 301 311 PF02747 0.247
LIG_PDZ_Class_2 433 438 PF00595 0.468
LIG_RPA_C_Fungi 235 247 PF08784 0.393
LIG_SH2_CRK 223 227 PF00017 0.247
LIG_SH2_NCK_1 182 186 PF00017 0.365
LIG_SH2_NCK_1 209 213 PF00017 0.390
LIG_SH2_PTP2 130 133 PF00017 0.341
LIG_SH2_SRC 182 185 PF00017 0.370
LIG_SH2_SRC 209 212 PF00017 0.389
LIG_SH2_STAP1 91 95 PF00017 0.419
LIG_SH2_STAT5 130 133 PF00017 0.291
LIG_SH2_STAT5 62 65 PF00017 0.351
LIG_SH3_3 17 23 PF00018 0.599
LIG_SH3_3 196 202 PF00018 0.380
LIG_SH3_3 3 9 PF00018 0.723
LIG_SUMO_SIM_anti_2 306 312 PF11976 0.247
LIG_SUMO_SIM_par_1 104 110 PF11976 0.394
LIG_SUMO_SIM_par_1 120 125 PF11976 0.289
LIG_SUMO_SIM_par_1 306 312 PF11976 0.247
LIG_SUMO_SIM_par_1 401 407 PF11976 0.262
LIG_TRAF2_1 110 113 PF00917 0.247
LIG_WRC_WIRS_1 133 138 PF05994 0.268
MOD_CK1_1 297 303 PF00069 0.393
MOD_CK1_1 368 374 PF00069 0.365
MOD_CK1_1 431 437 PF00069 0.468
MOD_CK2_1 101 107 PF00069 0.468
MOD_CK2_1 122 128 PF00069 0.306
MOD_CK2_1 201 207 PF00069 0.360
MOD_CK2_1 303 309 PF00069 0.247
MOD_CK2_1 368 374 PF00069 0.422
MOD_CK2_1 78 84 PF00069 0.488
MOD_Cter_Amidation 25 28 PF01082 0.507
MOD_GlcNHglycan 124 127 PF01048 0.306
MOD_GlcNHglycan 241 244 PF01048 0.247
MOD_GlcNHglycan 257 260 PF01048 0.247
MOD_GlcNHglycan 296 300 PF01048 0.262
MOD_GlcNHglycan 386 391 PF01048 0.262
MOD_GSK3_1 120 127 PF00069 0.262
MOD_GSK3_1 364 371 PF00069 0.359
MOD_LATS_1 151 157 PF00433 0.306
MOD_N-GLC_1 238 243 PF02516 0.247
MOD_NEK2_1 144 149 PF00069 0.247
MOD_NEK2_1 69 74 PF00069 0.401
MOD_PIKK_1 309 315 PF00454 0.247
MOD_PK_1 153 159 PF00069 0.341
MOD_PKA_2 239 245 PF00069 0.400
MOD_PKA_2 368 374 PF00069 0.365
MOD_Plk_1 178 184 PF00069 0.493
MOD_Plk_1 428 434 PF00069 0.470
MOD_Plk_2-3 107 113 PF00069 0.247
MOD_Plk_4 132 138 PF00069 0.247
MOD_Plk_4 144 150 PF00069 0.247
MOD_Plk_4 153 159 PF00069 0.247
MOD_Plk_4 167 173 PF00069 0.397
MOD_Plk_4 228 234 PF00069 0.298
MOD_Plk_4 241 247 PF00069 0.298
MOD_ProDKin_1 101 107 PF00069 0.479
MOD_ProDKin_1 273 279 PF00069 0.247
MOD_SUMO_for_1 384 387 PF00179 0.281
MOD_SUMO_rev_2 189 198 PF00179 0.349
MOD_SUMO_rev_2 318 326 PF00179 0.247
MOD_SUMO_rev_2 350 358 PF00179 0.397
MOD_SUMO_rev_2 386 396 PF00179 0.262
MOD_SUMO_rev_2 92 98 PF00179 0.503
TRG_DiLeu_BaEn_1 260 265 PF01217 0.284
TRG_ENDOCYTIC_2 130 133 PF00928 0.247
TRG_ENDOCYTIC_2 182 185 PF00928 0.399
TRG_ENDOCYTIC_2 209 212 PF00928 0.398
TRG_ENDOCYTIC_2 62 65 PF00928 0.351
TRG_ER_diArg_1 360 362 PF00400 0.503
TRG_ER_diArg_1 408 410 PF00400 0.262
TRG_NLS_Bipartite_1 347 363 PF00514 0.498
TRG_NLS_MonoCore_2 26 31 PF00514 0.535
TRG_NLS_MonoExtC_3 26 31 PF00514 0.535
TRG_NLS_MonoExtC_3 358 364 PF00514 0.489
TRG_NLS_MonoExtC_3 51 57 PF00514 0.496
TRG_NLS_MonoExtN_4 27 34 PF00514 0.583
TRG_NLS_MonoExtN_4 357 363 PF00514 0.492
TRG_Pf-PMV_PEXEL_1 360 364 PF00026 0.498

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4E9 Leptomonas seymouri 45% 100%
A0A0N0P5B8 Leptomonas seymouri 51% 99%
A0A0N1IGY9 Leptomonas seymouri 48% 100%
A0A0N1IM81 Leptomonas seymouri 98% 100%
A0A0N1PAS8 Leptomonas seymouri 42% 100%
A0A0S4IJE6 Bodo saltans 42% 100%
A0A0S4ITX1 Bodo saltans 49% 99%
A0A0S4IY28 Bodo saltans 47% 100%
A0A0S4JCD0 Bodo saltans 80% 100%
A0A0S4JDU3 Bodo saltans 52% 100%
A0A0S4JSD8 Bodo saltans 51% 100%
A0A1X0NMZ3 Trypanosomatidae 85% 100%
A0A1X0NNS1 Trypanosomatidae 52% 100%
A0A1X0NT86 Trypanosomatidae 48% 99%
A0A1X0NUX3 Trypanosomatidae 41% 100%
A0A1X0P1T5 Trypanosomatidae 51% 100%
A0A1X0P8T7 Trypanosomatidae 45% 100%
A0A3Q8IHU1 Leishmania donovani 33% 100%
A0A3Q8IJS0 Leishmania donovani 54% 100%
A0A3R7LUG9 Trypanosoma rangeli 45% 99%
A0A3R7N4Y5 Trypanosoma rangeli 53% 100%
A0A3S5H547 Leishmania donovani 43% 100%
A0A3S7WRY0 Leishmania donovani 48% 100%
A0A3S7WSK7 Leishmania donovani 100% 100%
A0A3S7WX14 Leishmania donovani 51% 99%
A0A3S7WX46 Leishmania donovani 42% 100%
A0A422NDS9 Trypanosoma rangeli 43% 100%
A0A422NLD8 Trypanosoma rangeli 83% 100%
A0A422NMN6 Trypanosoma rangeli 44% 100%
A0A422NUD9 Trypanosoma rangeli 53% 100%
A0JWY3 Arthrobacter sp. (strain FB24) 34% 74%
A1R6Q4 Paenarthrobacter aurescens (strain TC1) 36% 73%
A1TAQ3 Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1) 34% 71%
A3CV35 Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) 46% 100%
A4FBX6 Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) 36% 73%
A4G0S4 Methanococcus maripaludis (strain C5 / ATCC BAA-1333) 48% 100%
A4H3L6 Leishmania braziliensis 43% 100%
A4H6T6 Leishmania braziliensis 49% 100%
A4H795 Leishmania braziliensis 99% 100%
A4HCA3 Leishmania braziliensis 42% 100%
A4HCA7 Leishmania braziliensis 51% 99%
A4HME8 Leishmania braziliensis 32% 100%
A4HPV3 Leishmania braziliensis 54% 100%
A4HVN7 Leishmania infantum 100% 100%
A4HZT4 Leishmania infantum 42% 100%
A4HZT9 Leishmania infantum 51% 99%
A4IB20 Leishmania infantum 33% 100%
A4IE38 Leishmania infantum 54% 100%
A4TB65 Mycolicibacterium gilvum (strain PYR-GCK) 37% 71%
A6UQT3 Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) 49% 100%
A6VHR1 Methanococcus maripaludis (strain C7 / ATCC BAA-1331) 49% 100%
A7I8B8 Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8) 47% 100%
A9A916 Methanococcus maripaludis (strain C6 / ATCC BAA-1332) 49% 100%
B1MAH2 Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) 34% 73%
B1VDV2 Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) 37% 81%
B6YXR2 Thermococcus onnurineus (strain NA1) 47% 100%
B8GGN4 Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) 44% 100%
B8ZRF0 Mycobacterium leprae (strain Br4923) 33% 72%
C0ZZV2 Rhodococcus erythropolis (strain PR4 / NBRC 100887) 36% 74%
C3MRF1 Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) 45% 100%
C3MY47 Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) 45% 100%
C3MZI6 Sulfolobus islandicus (strain M.16.27) 45% 100%
C3N7K8 Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) 45% 100%
C3NFW6 Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) 45% 100%
C3PGA0 Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CIP 107346 / CN-1) 34% 84%
C4KIR6 Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) 45% 100%
C5A6P8 Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) 48% 100%
C6WIC8 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101) 37% 73%
C7PVU9 Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908) 35% 74%
C8XAR0 Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 / Y-104) 35% 74%
C9ZQC1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 53% 100%
C9ZRM0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 47% 100%
C9ZRM8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 98%
D0A259 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 45% 100%
D0A4A2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 48% 100%
D0A6K9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 83% 100%
D0LDS6 Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / BCRC 13721 / JCM 3198 / KCTC 3076 / NBRC 16047 / NCTC 10667) 34% 72%
D1BHU2 Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74) 35% 75%
D1BS23 Xylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07) 34% 81%
D2Q9C6 Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1) 39% 83%
D4GUJ7 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) 47% 100%
E9ACJ9 Leishmania major 43% 100%
E9AEU9 Leishmania major 33% 100%
E9AG43 Leishmania infantum 43% 100%
E9AGB0 Leishmania infantum 48% 100%
E9AJT7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 43% 100%
E9ANU8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 48% 100%
E9APD3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 100% 100%
E9ATM0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%
E9AVN9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 42% 100%
E9AVP4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 51% 99%
E9B605 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 100%
O04019 Arabidopsis thaliana 51% 100%
O14126 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 45% 100%
O16368 Caenorhabditis elegans 68% 99%
O17071 Caenorhabditis elegans 45% 100%
O23894 Brassica campestris 51% 100%
O26824 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 53% 100%
O28303 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) 52% 100%
O32617 Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1) 38% 69%
O42586 Xenopus laevis 49% 100%
O42587 Xenopus laevis 50% 100%
O42931 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 44% 100%
O50202 Rhodococcus erythropolis 36% 74%
O57940 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 49% 100%
O64982 Prunus persica 46% 100%
O74445 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 41% 100%
O74894 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 49% 100%
O76371 Caenorhabditis elegans 49% 100%
O88685 Mus musculus 50% 99%
P0DKJ9 Oryza sativa subsp. japonica 46% 100%
P0DKK0 Oryza sativa subsp. japonica 46% 100%
P17980 Homo sapiens 50% 100%
P33297 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 47% 100%
P33298 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 48% 100%
P33299 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 48% 94%
P34123 Dictyostelium discoideum 49% 100%
P35998 Homo sapiens 46% 100%
P36612 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 65% 98%
P40327 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 61% 100%
P43686 Homo sapiens 51% 100%
P46465 Oryza sativa subsp. japonica 51% 100%
P46466 Oryza sativa subsp. japonica 64% 98%
P46470 Xenopus laevis 47% 95%
P46471 Mus musculus 46% 100%
P46472 Xenopus laevis 46% 100%
P46502 Caenorhabditis elegans 51% 100%
P46507 Manduca sexta 51% 100%
P46509 Mycobacterium leprae (strain TN) 33% 72%
P48601 Drosophila melanogaster 66% 100%
P53549 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 44% 100%
P54775 Mus musculus 51% 100%
P54776 Solanum lycopersicum 51% 100%
P54778 Solanum tuberosum 48% 100%
P62191 Homo sapiens 70% 100%
P62192 Mus musculus 70% 100%
P62193 Rattus norvegicus 70% 100%
P62194 Bos taurus 47% 100%
P62195 Homo sapiens 47% 100%
P62196 Mus musculus 47% 100%
P62197 Sus scrofa 47% 100%
P62198 Rattus norvegicus 47% 100%
P62333 Homo sapiens 43% 100%
P62334 Mus musculus 43% 100%
P62335 Ictidomys tridecemlineatus 43% 100%
P71408 Helicobacter pylori (strain ATCC 700392 / 26695) 37% 69%
P78578 Aspergillus niger 49% 100%
P85200 Helianthus annuus 48% 100%
Q01939 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 52% 100%
Q0W257 Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) 45% 100%
Q18787 Caenorhabditis elegans 46% 100%
Q25544 Naegleria fowleri 53% 100%
Q2FQ56 Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) 50% 100%
Q2KIW6 Bos taurus 43% 100%
Q3T030 Bos taurus 51% 100%
Q41365 Spinacia oleracea 46% 100%
Q4JVP5 Corynebacterium jeikeium (strain K411) 35% 85%
Q4Q0X8 Leishmania major 54% 100%
Q4QBT5 Leishmania major 51% 100%
Q4QBU0 Leishmania major 42% 100%
Q4QGS2 Leishmania major 48% 100%
Q4R4R0 Macaca fascicularis 46% 100%
Q4R7L3 Macaca fascicularis 51% 100%
Q54PJ1 Dictyostelium discoideum 44% 100%
Q54PN7 Dictyostelium discoideum 50% 100%
Q55BV5 Dictyostelium discoideum 62% 100%
Q58576 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 50% 100%
Q5E9F9 Bos taurus 46% 100%
Q5JHS5 Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) 48% 100%
Q5R8D7 Pongo abelii 46% 100%
Q5UT56 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) 44% 100%
Q63347 Rattus norvegicus 46% 100%
Q63569 Rattus norvegicus 50% 100%
Q63570 Rattus norvegicus 51% 100%
Q67T82 Symbiobacterium thermophilum (strain T / IAM 14863) 37% 75%
Q6LWR0 Methanococcus maripaludis (strain S2 / LL) 49% 100%
Q86JA1 Dictyostelium discoideum 46% 100%
Q8FTE3 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) 39% 83%
Q8PY58 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) 43% 100%
Q8SQI9 Encephalitozoon cuniculi (strain GB-M1) 54% 100%
Q8SR13 Encephalitozoon cuniculi (strain GB-M1) 47% 100%
Q8SRH0 Encephalitozoon cuniculi (strain GB-M1) 60% 100%
Q8TI88 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) 43% 100%
Q8TX03 Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) 48% 100%
Q8U4H3 Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) 48% 100%
Q90732 Gallus gallus 69% 100%
Q975U2 Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) 46% 100%
Q980M1 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) 46% 100%
Q9HNP9 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 48% 100%
Q9HRW6 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 46% 100%
Q9MAK9 Arabidopsis thaliana 47% 100%
Q9SEI2 Arabidopsis thaliana 51% 100%
Q9SEI3 Arabidopsis thaliana 43% 100%
Q9SEI4 Arabidopsis thaliana 49% 100%
Q9SL67 Arabidopsis thaliana 67% 99%
Q9SSB4 Arabidopsis thaliana 46% 94%
Q9SSB5 Arabidopsis thaliana 46% 100%
Q9SZD4 Arabidopsis thaliana 66% 99%
Q9V287 Pyrococcus abyssi (strain GE5 / Orsay) 47% 100%
Q9XTT9 Caenorhabditis elegans 53% 100%
Q9YAC7 Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) 51% 100%
Q9ZM66 Helicobacter pylori (strain J99 / ATCC 700824) 37% 69%
V5AV12 Trypanosoma cruzi 83% 100%
V5B5X1 Trypanosoma cruzi 42% 100%
V5B5X6 Trypanosoma cruzi 48% 100%
V5BKL6 Trypanosoma cruzi 53% 100%
V5BSS5 Trypanosoma cruzi 44% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS