Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QG29_LEIMA

TriTrypDb:

LmjF.13.1250 , LMJLV39_130016700 , LMJSD75_130016700

Length:

217

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

Expansion

Sequence features

Q4QG29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QG29

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	41	43	PF00675	0.443
CLV_PCSK_FUR_1	94	98	PF00082	0.431
CLV_PCSK_KEX2_1	135	137	PF00082	0.764
CLV_PCSK_KEX2_1	176	178	PF00082	0.712
CLV_PCSK_KEX2_1	215	217	PF00082	0.732
CLV_PCSK_KEX2_1	65	67	PF00082	0.422
CLV_PCSK_KEX2_1	96	98	PF00082	0.417
CLV_PCSK_PC1ET2_1	135	137	PF00082	0.714
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.712
CLV_PCSK_PC1ET2_1	215	217	PF00082	0.732
CLV_PCSK_PC1ET2_1	65	67	PF00082	0.422
CLV_PCSK_PC1ET2_1	96	98	PF00082	0.417
CLV_PCSK_PC7_1	131	137	PF00082	0.682
CLV_PCSK_SKI1_1	135	139	PF00082	0.706
CLV_PCSK_SKI1_1	65	69	PF00082	0.434
DEG_Nend_UBRbox_3	1	3	PF02207	0.642
DEG_SCF_FBW7_1	6	13	PF00400	0.629
DOC_CKS1_1	130	135	PF01111	0.467
DOC_CKS1_1	78	83	PF01111	0.695
DOC_CYCLIN_RxL_1	131	140	PF00134	0.492
DOC_USP7_MATH_1	10	14	PF00917	0.640
DOC_USP7_MATH_1	188	192	PF00917	0.452
DOC_USP7_MATH_1	67	71	PF00917	0.634
DOC_WW_Pin1_4	129	134	PF00397	0.459
DOC_WW_Pin1_4	44	49	PF00397	0.633
DOC_WW_Pin1_4	6	11	PF00397	0.629
DOC_WW_Pin1_4	77	82	PF00397	0.698
LIG_14-3-3_CanoR_1	157	163	PF00244	0.514
LIG_14-3-3_CanoR_1	94	100	PF00244	0.607
LIG_BRCT_BRCA1_1	150	154	PF00533	0.440
LIG_Clathr_ClatBox_1	107	111	PF01394	0.405
LIG_FHA_1	84	90	PF00498	0.701
LIG_SH2_STAP1	150	154	PF00017	0.440
LIG_SH2_STAT5	126	129	PF00017	0.559
LIG_SH3_3	127	133	PF00018	0.545
LIG_SH3_3	2	8	PF00018	0.642
LIG_SH3_3	79	85	PF00018	0.691
LIG_SUMO_SIM_par_1	106	111	PF11976	0.514
MOD_CDK_SPxK_1	129	135	PF00069	0.463
MOD_CDK_SPxK_1	44	50	PF00069	0.634
MOD_CDK_SPxxK_3	129	136	PF00069	0.469
MOD_CK1_1	14	20	PF00069	0.627
MOD_CK1_1	148	154	PF00069	0.507
MOD_CK1_1	155	161	PF00069	0.511
MOD_CK1_1	166	172	PF00069	0.484
MOD_CK1_1	190	196	PF00069	0.454
MOD_CK1_1	202	208	PF00069	0.511
MOD_CK1_1	95	101	PF00069	0.583
MOD_CK2_1	156	162	PF00069	0.575
MOD_CK2_1	175	181	PF00069	0.417
MOD_CK2_1	193	199	PF00069	0.545
MOD_CK2_1	67	73	PF00069	0.604
MOD_Cter_Amidation	133	136	PF01082	0.687
MOD_Cter_Amidation	63	66	PF01082	0.428
MOD_GlcNHglycan	159	162	PF01048	0.634
MOD_GlcNHglycan	201	204	PF01048	0.702
MOD_GlcNHglycan	51	54	PF01048	0.502
MOD_GlcNHglycan	69	72	PF01048	0.460
MOD_GSK3_1	145	152	PF00069	0.535
MOD_GSK3_1	153	160	PF00069	0.490
MOD_GSK3_1	166	173	PF00069	0.514
MOD_GSK3_1	184	191	PF00069	0.462
MOD_GSK3_1	6	13	PF00069	0.629
MOD_LATS_1	28	34	PF00433	0.621
MOD_NEK2_1	163	168	PF00069	0.511
MOD_PIKK_1	14	20	PF00454	0.622
MOD_PIKK_1	202	208	PF00454	0.485
MOD_PKA_2	156	162	PF00069	0.511
MOD_PKA_2	166	172	PF00069	0.458
MOD_PKA_2	49	55	PF00069	0.642
MOD_PKA_2	56	62	PF00069	0.622
MOD_ProDKin_1	129	135	PF00069	0.463
MOD_ProDKin_1	44	50	PF00069	0.634
MOD_ProDKin_1	6	12	PF00069	0.630
MOD_ProDKin_1	77	83	PF00069	0.696
MOD_SUMO_rev_2	156	166	PF00179	0.436
MOD_SUMO_rev_2	70	77	PF00179	0.630
TRG_DiLeu_BaLyEn_6	133	138	PF01217	0.494
TRG_ENDOCYTIC_2	125	128	PF00928	0.453
TRG_Pf-PMV_PEXEL_1	135	139	PF00026	0.703

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H6P6	Leishmania donovani	87%	100%
A4H7A8	Leishmania braziliensis	67%	100%
A4HVQ3	Leishmania infantum	87%	100%
E9APE9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	84%