Complex1_LYR_dom domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Complex 1 protein (LYR family), putative

Species:

Leishmania major

UniProt:

Q4QG24_LEIMA

TriTrypDb:

LmjF.13.1300 , LMJLV39_130017300 , LMJSD75_130017300

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QG24

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QG24

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.374
CLV_NRD_NRD_1	121	123	PF00675	0.508
CLV_NRD_NRD_1	186	188	PF00675	0.492
CLV_NRD_NRD_1	46	48	PF00675	0.283
CLV_NRD_NRD_1	9	11	PF00675	0.491
CLV_PCSK_FUR_1	44	48	PF00082	0.317
CLV_PCSK_KEX2_1	121	123	PF00082	0.599
CLV_PCSK_KEX2_1	186	188	PF00082	0.492
CLV_PCSK_KEX2_1	46	48	PF00082	0.283
CLV_PCSK_KEX2_1	9	11	PF00082	0.664
CLV_PCSK_SKI1_1	157	161	PF00082	0.519
CLV_PCSK_SKI1_1	186	190	PF00082	0.490
CLV_PCSK_SKI1_1	32	36	PF00082	0.317
CLV_PCSK_SKI1_1	74	78	PF00082	0.315
CLV_PCSK_SKI1_1	83	87	PF00082	0.283
DEG_Nend_Nbox_1	1	3	PF02207	0.707
DOC_MAPK_gen_1	23	30	PF00069	0.274
DOC_PP4_FxxP_1	58	61	PF00568	0.283
DOC_USP7_MATH_1	42	46	PF00917	0.283
DOC_USP7_UBL2_3	153	157	PF12436	0.554
LIG_14-3-3_CanoR_1	130	139	PF00244	0.567
LIG_14-3-3_CanoR_1	29	35	PF00244	0.366
LIG_14-3-3_CanoR_1	3	7	PF00244	0.491
LIG_14-3-3_CanoR_1	55	59	PF00244	0.377
LIG_FHA_1	131	137	PF00498	0.459
LIG_FHA_1	2	8	PF00498	0.603
LIG_FHA_1	49	55	PF00498	0.305
LIG_FHA_2	55	61	PF00498	0.317
LIG_FHA_2	85	91	PF00498	0.422
LIG_LIR_Apic_2	56	61	PF02991	0.317
LIG_LIR_Nem_3	141	146	PF02991	0.490
LIG_LIR_Nem_3	70	76	PF02991	0.323
LIG_Pex14_2	184	188	PF04695	0.515
LIG_Pex14_2	192	196	PF04695	0.517
LIG_REV1ctd_RIR_1	181	191	PF16727	0.531
LIG_SH2_CRK	31	35	PF00017	0.329
LIG_SH2_CRK	73	77	PF00017	0.317
LIG_SH2_GRB2like	143	146	PF00017	0.512
LIG_SH2_STAP1	88	92	PF00017	0.317
LIG_SH2_STAT5	107	110	PF00017	0.377
LIG_SH3_3	173	179	PF00018	0.560
LIG_TYR_ITIM	71	76	PF00017	0.317
MOD_CK1_1	84	90	PF00069	0.390
MOD_CK2_1	84	90	PF00069	0.426
MOD_CK2_1	94	100	PF00069	0.244
MOD_GSK3_1	130	137	PF00069	0.461
MOD_NEK2_1	1	6	PF00069	0.602
MOD_NEK2_1	139	144	PF00069	0.480
MOD_NEK2_1	30	35	PF00069	0.366
MOD_PK_1	81	87	PF00069	0.377
MOD_PKA_2	2	8	PF00069	0.555
MOD_PKA_2	54	60	PF00069	0.377
MOD_Plk_2-3	48	54	PF00069	0.283
MOD_Plk_2-3	64	70	PF00069	0.283
MOD_Plk_4	139	145	PF00069	0.489
MOD_Plk_4	2	8	PF00069	0.683
MOD_SUMO_rev_2	109	117	PF00179	0.412
MOD_SUMO_rev_2	134	142	PF00179	0.542
TRG_ENDOCYTIC_2	143	146	PF00928	0.490
TRG_ENDOCYTIC_2	31	34	PF00928	0.331
TRG_ENDOCYTIC_2	73	76	PF00928	0.317
TRG_ER_diArg_1	120	122	PF00400	0.346
TRG_ER_diArg_1	166	169	PF00400	0.529
TRG_ER_diArg_1	185	187	PF00400	0.507
TRG_ER_diArg_1	22	25	PF00400	0.370
TRG_ER_diArg_1	43	46	PF00400	0.317

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7Q9	Leptomonas seymouri	79%	100%
A0A0S4JJ94	Bodo saltans	66%	100%
A0A3Q8I9K5	Leishmania donovani	97%	100%
A4H7B3	Leishmania braziliensis	90%	100%
A4HVQ8	Leishmania infantum	97%	100%
D0A6I2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	87%
E9APF4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%