B30.2/SPRY domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SPRY domain/HECT-domain (ubiquitin-transferase), putative

Species:

Leishmania major

UniProt:

Q4QG07_LEIMA

TriTrypDb:

LmjF.13.1470 , LMJLV39_130019200 , LMJSD75_130019300

Length:

5636

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

Q4QG07

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	6
GO:0004842	ubiquitin-protein transferase activity	4	6
GO:0016740	transferase activity	2	6
GO:0019787	ubiquitin-like protein transferase activity	3	6
GO:0140096	catalytic activity, acting on a protein	2	6

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1220	1224	PF00656	0.641
CLV_C14_Caspase3-7	1235	1239	PF00656	0.655
CLV_C14_Caspase3-7	1244	1248	PF00656	0.662
CLV_C14_Caspase3-7	1408	1412	PF00656	0.574
CLV_C14_Caspase3-7	1414	1418	PF00656	0.622
CLV_C14_Caspase3-7	1468	1472	PF00656	0.585
CLV_C14_Caspase3-7	1855	1859	PF00656	0.500
CLV_C14_Caspase3-7	2432	2436	PF00656	0.446
CLV_C14_Caspase3-7	2649	2653	PF00656	0.429
CLV_C14_Caspase3-7	2889	2893	PF00656	0.332

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2H9	Leptomonas seymouri	52%	100%
A0A3S7WSP0	Leishmania donovani	95%	100%
A4H7C8	Leishmania braziliensis	79%	100%
A4HVS5	Leishmania infantum	95%	100%
E9APH1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%

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