Putative phosphoprotein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplastid-specific phospho-protein phosphatase, putative

Species:

Leishmania major

UniProt:

Q4QG03_LEIMA

TriTrypDb:

LmjF.13.1510 , LMJLV39_130020400 , LMJSD75_130019700

Length:

433

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 12
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 28

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 25
NetGPI	no	yes: 0, no: 25

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	4
GO:0005737	cytoplasm	2	4
GO:0043226	organelle	2	4
GO:0043227	membrane-bounded organelle	3	4
GO:0043229	intracellular organelle	3	4
GO:0043231	intracellular membrane-bounded organelle	4	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

Q4QG03

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QG03

Function

Biological processes
Term	Name	Level	Count
GO:0000724	double-strand break repair via homologous recombination	7	4
GO:0000725	recombinational repair	6	4
GO:0006139	nucleobase-containing compound metabolic process	3	4
GO:0006259	DNA metabolic process	4	4
GO:0006281	DNA repair	5	4
GO:0006302	double-strand break repair	6	4
GO:0006310	DNA recombination	5	4
GO:0006725	cellular aromatic compound metabolic process	3	4
GO:0006807	nitrogen compound metabolic process	2	4
GO:0006950	response to stress	2	4
GO:0006974	DNA damage response	4	4
GO:0008152	metabolic process	1	4
GO:0009987	cellular process	1	4
GO:0033554	cellular response to stress	3	4
GO:0034641	cellular nitrogen compound metabolic process	3	4
GO:0043170	macromolecule metabolic process	3	4
GO:0044237	cellular metabolic process	2	4
GO:0044238	primary metabolic process	2	4
GO:0044260	obsolete cellular macromolecule metabolic process	3	4
GO:0046483	heterocycle metabolic process	3	4
GO:0050896	response to stimulus	1	4
GO:0051716	cellular response to stimulus	2	4
GO:0071704	organic substance metabolic process	2	4
GO:0090304	nucleic acid metabolic process	4	4
GO:1901360	organic cyclic compound metabolic process	3	4

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	26
GO:0004721	phosphoprotein phosphatase activity	3	25
GO:0004722	protein serine/threonine phosphatase activity	4	25
GO:0016787	hydrolase activity	2	26
GO:0016788	hydrolase activity, acting on ester bonds	3	25
GO:0016791	phosphatase activity	5	25
GO:0017018	myosin phosphatase activity	5	25
GO:0042578	phosphoric ester hydrolase activity	4	25
GO:0140096	catalytic activity, acting on a protein	2	25

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	105	109	PF00656	0.676
CLV_NRD_NRD_1	176	178	PF00675	0.455
CLV_NRD_NRD_1	403	405	PF00675	0.286
CLV_NRD_NRD_1	421	423	PF00675	0.409
CLV_NRD_NRD_1	92	94	PF00675	0.499
CLV_PCSK_KEX2_1	175	177	PF00082	0.422
CLV_PCSK_KEX2_1	330	332	PF00082	0.147
CLV_PCSK_KEX2_1	403	405	PF00082	0.284
CLV_PCSK_KEX2_1	68	70	PF00082	0.715
CLV_PCSK_KEX2_1	92	94	PF00082	0.539
CLV_PCSK_PC1ET2_1	330	332	PF00082	0.147
CLV_PCSK_PC1ET2_1	68	70	PF00082	0.502
CLV_PCSK_SKI1_1	186	190	PF00082	0.263
CLV_PCSK_SKI1_1	258	262	PF00082	0.297
CLV_PCSK_SKI1_1	375	379	PF00082	0.333
CLV_PCSK_SKI1_1	68	72	PF00082	0.504
DOC_ANK_TNKS_1	176	183	PF00023	0.253
DOC_CYCLIN_RxL_1	66	77	PF00134	0.334
DOC_CYCLIN_yCln2_LP_2	261	267	PF00134	0.297
DOC_MAPK_gen_1	390	398	PF00069	0.203
DOC_MAPK_HePTP_8	133	145	PF00069	0.366
DOC_MAPK_MEF2A_6	136	145	PF00069	0.325
DOC_MAPK_MEF2A_6	196	205	PF00069	0.294
DOC_MAPK_MEF2A_6	258	265	PF00069	0.297
DOC_MAPK_NFAT4_5	258	266	PF00069	0.297
DOC_PP2B_LxvP_1	261	264	PF13499	0.297
DOC_PP4_FxxP_1	380	383	PF00568	0.268
DOC_SPAK_OSR1_1	275	279	PF12202	0.297
DOC_USP7_MATH_1	102	106	PF00917	0.727
DOC_USP7_MATH_1	2	6	PF00917	0.693
DOC_USP7_MATH_1	240	244	PF00917	0.351
DOC_USP7_MATH_1	342	346	PF00917	0.416
DOC_USP7_MATH_1	413	417	PF00917	0.423
DOC_WW_Pin1_4	22	27	PF00397	0.507
DOC_WW_Pin1_4	281	286	PF00397	0.310
DOC_WW_Pin1_4	53	58	PF00397	0.595
DOC_WW_Pin1_4	74	79	PF00397	0.402
DOC_WW_Pin1_4	81	86	PF00397	0.350
LIG_14-3-3_CanoR_1	18	26	PF00244	0.490
LIG_14-3-3_CanoR_1	196	202	PF00244	0.374
LIG_14-3-3_CanoR_1	275	285	PF00244	0.379
LIG_14-3-3_CanoR_1	298	306	PF00244	0.216
LIG_14-3-3_CanoR_1	375	380	PF00244	0.374
LIG_14-3-3_CanoR_1	38	44	PF00244	0.459
LIG_14-3-3_CanoR_1	4	9	PF00244	0.492
LIG_14-3-3_CanoR_1	422	428	PF00244	0.641
LIG_AP2alpha_1	428	432	PF02296	0.360
LIG_BIR_II_1	1	5	PF00653	0.728
LIG_BRCT_BRCA1_1	344	348	PF00533	0.360
LIG_BRCT_BRCA1_1	79	83	PF00533	0.530
LIG_Clathr_ClatBox_1	140	144	PF01394	0.315
LIG_FHA_1	129	135	PF00498	0.411
LIG_FHA_1	148	154	PF00498	0.161
LIG_FHA_1	164	170	PF00498	0.422
LIG_FHA_1	228	234	PF00498	0.300
LIG_FHA_1	239	245	PF00498	0.287
LIG_FHA_1	321	327	PF00498	0.360
LIG_FHA_1	5	11	PF00498	0.516
LIG_FHA_1	54	60	PF00498	0.445
LIG_FHA_2	305	311	PF00498	0.362
LIG_FHA_2	369	375	PF00498	0.460
LIG_Integrin_RGD_1	96	98	PF01839	0.452
LIG_LIR_Apic_2	378	383	PF02991	0.304
LIG_LIR_Gen_1	163	173	PF02991	0.422
LIG_LIR_Gen_1	184	194	PF02991	0.302
LIG_LIR_Gen_1	250	261	PF02991	0.331
LIG_LIR_Gen_1	271	278	PF02991	0.454
LIG_LIR_Gen_1	351	360	PF02991	0.318
LIG_LIR_Gen_1	425	433	PF02991	0.496
LIG_LIR_LC3C_4	149	153	PF02991	0.325
LIG_LIR_Nem_3	163	168	PF02991	0.381
LIG_LIR_Nem_3	213	217	PF02991	0.355
LIG_LIR_Nem_3	231	237	PF02991	0.340
LIG_LIR_Nem_3	250	256	PF02991	0.255
LIG_LIR_Nem_3	271	276	PF02991	0.444
LIG_LIR_Nem_3	351	357	PF02991	0.353
LIG_LIR_Nem_3	80	86	PF02991	0.531
LIG_LYPXL_yS_3	214	217	PF13949	0.347
LIG_MAD2	375	383	PF02301	0.332
LIG_PCNA_yPIPBox_3	359	369	PF02747	0.362
LIG_Pex14_2	428	432	PF04695	0.513
LIG_PTB_Apo_2	116	123	PF02174	0.321
LIG_PTB_Phospho_1	116	122	PF10480	0.329
LIG_SH2_CRK	165	169	PF00017	0.425
LIG_SH2_CRK	234	238	PF00017	0.368
LIG_SH2_CRK	385	389	PF00017	0.400
LIG_SH2_NCK_1	112	116	PF00017	0.379
LIG_SH2_NCK_1	410	414	PF00017	0.406
LIG_SH2_STAP1	165	169	PF00017	0.297
LIG_SH2_STAT5	112	115	PF00017	0.584
LIG_SH2_STAT5	122	125	PF00017	0.469
LIG_SH2_STAT5	165	168	PF00017	0.297
LIG_SH2_STAT5	193	196	PF00017	0.302
LIG_SH2_STAT5	219	222	PF00017	0.379
LIG_SH2_STAT5	385	388	PF00017	0.372
LIG_SH3_3	209	215	PF00018	0.287
LIG_SH3_3	96	102	PF00018	0.491
LIG_SUMO_SIM_anti_2	142	147	PF11976	0.384
LIG_SUMO_SIM_anti_2	149	156	PF11976	0.237
LIG_SUMO_SIM_anti_2	200	205	PF11976	0.286
LIG_SUMO_SIM_par_1	139	144	PF11976	0.329
LIG_SUMO_SIM_par_1	149	156	PF11976	0.218
LIG_SUMO_SIM_par_1	374	381	PF11976	0.330
LIG_SUMO_SIM_par_1	5	12	PF11976	0.498
LIG_TYR_ITIM	212	217	PF00017	0.347
LIG_UBA3_1	205	211	PF00899	0.295
MOD_CDK_SPxxK_3	22	29	PF00069	0.501
MOD_CK1_1	22	28	PF00069	0.738
MOD_CK1_1	320	326	PF00069	0.332
MOD_CK1_1	52	58	PF00069	0.542
MOD_CK2_1	304	310	PF00069	0.422
MOD_CK2_1	39	45	PF00069	0.722
MOD_GlcNHglycan	253	256	PF01048	0.410
MOD_GlcNHglycan	342	345	PF01048	0.395
MOD_GlcNHglycan	380	383	PF01048	0.336
MOD_GlcNHglycan	411	414	PF01048	0.371
MOD_GlcNHglycan	45	48	PF01048	0.604
MOD_GlcNHglycan	51	54	PF01048	0.602
MOD_GlcNHglycan	74	77	PF01048	0.517
MOD_GlcNHglycan	79	82	PF01048	0.476
MOD_GSK3_1	235	242	PF00069	0.316
MOD_GSK3_1	247	254	PF00069	0.416
MOD_GSK3_1	39	46	PF00069	0.616
MOD_GSK3_1	409	416	PF00069	0.454
MOD_GSK3_1	48	55	PF00069	0.582
MOD_GSK3_1	77	84	PF00069	0.349
MOD_N-GLC_1	299	304	PF02516	0.267
MOD_N-GLC_1	38	43	PF02516	0.699
MOD_N-GLC_2	125	127	PF02516	0.255
MOD_N-GLC_2	384	386	PF02516	0.355
MOD_NEK2_1	164	169	PF00069	0.422
MOD_NEK2_1	19	24	PF00069	0.479
MOD_NEK2_1	276	281	PF00069	0.313
MOD_PIKK_1	102	108	PF00454	0.676
MOD_PIKK_1	110	116	PF00454	0.621
MOD_PKA_2	17	23	PF00069	0.748
MOD_PKA_2	3	9	PF00069	0.469
MOD_PKA_2	421	427	PF00069	0.562
MOD_Plk_1	38	44	PF00069	0.580
MOD_Plk_4	113	119	PF00069	0.579
MOD_Plk_4	147	153	PF00069	0.410
MOD_Plk_4	164	170	PF00069	0.422
MOD_Plk_4	213	219	PF00069	0.466
MOD_Plk_4	268	274	PF00069	0.457
MOD_Plk_4	375	381	PF00069	0.301
MOD_Plk_4	39	45	PF00069	0.640
MOD_Plk_4	4	10	PF00069	0.535
MOD_ProDKin_1	22	28	PF00069	0.505
MOD_ProDKin_1	281	287	PF00069	0.310
MOD_ProDKin_1	53	59	PF00069	0.595
MOD_ProDKin_1	74	80	PF00069	0.401
MOD_ProDKin_1	81	87	PF00069	0.348
MOD_SUMO_for_1	210	213	PF00179	0.254
MOD_SUMO_rev_2	226	231	PF00179	0.253
MOD_SUMO_rev_2	6	15	PF00179	0.675
TRG_DiLeu_BaEn_1	202	207	PF01217	0.283
TRG_DiLeu_BaEn_1	213	218	PF01217	0.308
TRG_DiLeu_LyEn_5	82	87	PF01217	0.343
TRG_ENDOCYTIC_2	165	168	PF00928	0.442
TRG_ENDOCYTIC_2	214	217	PF00928	0.356
TRG_ENDOCYTIC_2	234	237	PF00928	0.268
TRG_ENDOCYTIC_2	273	276	PF00928	0.443
TRG_ENDOCYTIC_2	385	388	PF00928	0.343
TRG_ER_diArg_1	175	177	PF00400	0.405
TRG_ER_diArg_1	403	405	PF00400	0.561
TRG_ER_diArg_1	91	93	PF00400	0.533
TRG_Pf-PMV_PEXEL_1	404	408	PF00026	0.388

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7Y2	Leptomonas seymouri	29%	79%
A0A0N1HSR2	Leptomonas seymouri	33%	100%
A0A0N1I0V3	Leptomonas seymouri	34%	100%
A0A0N1I548	Leptomonas seymouri	32%	68%
A0A0N1ILH2	Leptomonas seymouri	28%	100%
A0A0N1P9X9	Leptomonas seymouri	34%	100%
A0A0N1PBN9	Leptomonas seymouri	32%	92%
A0A0N1PD03	Leptomonas seymouri	26%	98%
A0A0N1PDK9	Leptomonas seymouri	36%	100%
A0A0S4IIW0	Bodo saltans	33%	100%
A0A0S4IS15	Bodo saltans	45%	90%
A0A0S4IYE4	Bodo saltans	32%	78%
A0A0S4J1J1	Bodo saltans	45%	100%
A0A0S4J323	Bodo saltans	39%	75%
A0A0S4JDD1	Bodo saltans	31%	96%
A0A0S4JEU6	Bodo saltans	36%	92%
A0A0S4JJ52	Bodo saltans	33%	100%
A0A0S4JJ96	Bodo saltans	35%	100%
A0A0S4JJH3	Bodo saltans	31%	100%
A0A0S4JP77	Bodo saltans	31%	68%
A0A0S4KGD7	Bodo saltans	38%	100%
A0A1X0NJI7	Trypanosomatidae	50%	78%
A0A1X0NNN6	Trypanosomatidae	38%	100%
A0A1X0NPA5	Trypanosomatidae	33%	67%
A0A1X0NUA6	Trypanosomatidae	31%	100%
A0A1X0P2R2	Trypanosomatidae	32%	68%
A0A1X0P6J3	Trypanosomatidae	34%	100%
A0A1X0P7H9	Trypanosomatidae	30%	97%
A0A1X0P7Q5	Trypanosomatidae	30%	100%
A0A1X0P9R6	Trypanosomatidae	40%	96%
A0A1X0PAK9	Trypanosomatidae	32%	100%
A0A3Q8I8M6	Leishmania donovani	91%	100%
A0A3Q8ID20	Leishmania donovani	29%	90%
A0A3Q8IFB2	Leishmania donovani	32%	100%
A0A3Q8IH18	Leishmania donovani	41%	100%
A0A3Q8II54	Leishmania donovani	79%	74%
A0A3R7KQR6	Trypanosoma rangeli	36%	100%
A0A3R7M399	Trypanosoma rangeli	42%	100%
A0A3R7MBA3	Trypanosoma rangeli	29%	97%
A0A3R7MFZ7	Trypanosoma rangeli	33%	100%
A0A3R7MM48	Trypanosoma rangeli	31%	100%
A0A3R7NXP6	Trypanosoma rangeli	33%	67%
A0A3S5H5F8	Leishmania donovani	32%	68%
A0A3S5H6D4	Leishmania donovani	33%	66%
A0A3S5H6T9	Leishmania donovani	32%	100%
A0A3S5H7Q6	Leishmania donovani	34%	100%
A0A3S7WZ39	Leishmania donovani	35%	100%
A0A3S7X190	Leishmania donovani	35%	100%
A0A3S7X1Y0	Leishmania donovani	34%	100%
A0A3S7X7I6	Leishmania donovani	31%	100%
A0A3S7X7J8	Leishmania donovani	34%	100%
A0A3S7X7K2	Leishmania donovani	33%	100%
A0A3S7X8K6	Leishmania donovani	34%	100%
A0A3S7XAY3	Leishmania donovani	30%	100%
A0A422N1U7	Trypanosoma rangeli	32%	72%
A0A422N9D5	Trypanosoma rangeli	32%	100%
A0A422NKG0	Trypanosoma rangeli	35%	100%
A0A422NYB5	Trypanosoma rangeli	32%	68%
A0A422P483	Trypanosoma rangeli	47%	100%
A0C1E4	Paramecium tetraurelia	36%	100%
A0DJ90	Paramecium tetraurelia	35%	100%
A2X2G3	Oryza sativa subsp. indica	38%	100%
A2XN40	Oryza sativa subsp. indica	35%	100%
A2YEB4	Oryza sativa subsp. indica	38%	100%
A3C4N5	Oryza sativa subsp. japonica	35%	100%
A4H456	Leishmania braziliensis	32%	68%
A4H5M4	Leishmania braziliensis	33%	67%
A4H7D2	Leishmania braziliensis	73%	79%
A4H7E7	Leishmania braziliensis	72%	74%
A4H7Z3	Leishmania braziliensis	32%	100%
A4HAI7	Leishmania braziliensis	32%	100%
A4HAI8	Leishmania braziliensis	32%	94%
A4HAI9	Leishmania braziliensis	30%	100%
A4HAJ8	Leishmania braziliensis	34%	100%
A4HBE2	Leishmania braziliensis	36%	100%
A4HF98	Leishmania braziliensis	29%	79%
A4HGA9	Leishmania braziliensis	35%	100%
A4HJQ1	Leishmania braziliensis	35%	100%
A4HKU9	Leishmania braziliensis	41%	100%
A4HP65	Leishmania braziliensis	31%	100%
A4HSD9	Leishmania infantum	32%	68%
A4HTW1	Leishmania infantum	33%	66%
A4HVT0	Leishmania infantum	90%	100%
A4HVT6	Leishmania infantum	79%	74%
A4HWC1	Leishmania infantum	32%	100%
A4I1H6	Leishmania infantum	35%	100%
A4I2J0	Leishmania infantum	29%	90%
A4I3E3	Leishmania infantum	35%	100%
A4I400	Leishmania infantum	34%	100%
A4I768	Leishmania infantum	34%	100%
A4I8C8	Leishmania infantum	41%	100%
A4I9P2	Leishmania infantum	34%	100%
A4IAJ0	Leishmania infantum	34%	100%
A4IDH0	Leishmania infantum	30%	100%
A6H772	Bos taurus	36%	100%
A8WGP3	Danio rerio	36%	100%
A8XE00	Caenorhabditis briggsae	37%	100%
A9JRC7	Danio rerio	36%	100%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
C9ZPX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	68%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
D0A366	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	68%
D0A9C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	68%
E9AHS9	Leishmania infantum	33%	100%
E9AHT0	Leishmania infantum	32%	100%
E9AHT1	Leishmania infantum	32%	100%
E9AKB4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	68%
E9AMP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	66%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
E9API1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	74%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9AYN4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	86%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
G5EGK8	Caenorhabditis elegans	36%	100%
O00743	Homo sapiens	35%	100%
O04860	Nicotiana tabacum	34%	100%
O04951	Arabidopsis thaliana	36%	100%
O14829	Homo sapiens	25%	66%
O35655	Mus musculus	27%	67%
O42773	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	33%	68%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
O76932	Drosophila melanogaster	37%	100%
O82734	Arabidopsis thaliana	36%	100%
P0C5D7	Oryza sativa subsp. indica	35%	100%
P11084	Oryctolagus cuniculus	36%	100%
P11493	Sus scrofa	36%	100%
P11611	Oryctolagus cuniculus	35%	100%
P14747	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	72%
P16298	Homo sapiens	32%	83%
P20651	Rattus norvegicus	32%	82%
P23287	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	78%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	100%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P23696	Drosophila melanogaster	35%	100%
P23778	Brassica napus	34%	100%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P32945	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	79%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
P48452	Bos taurus	32%	83%
P48453	Mus musculus	32%	82%
P48454	Homo sapiens	32%	85%
P48455	Mus musculus	33%	84%
P48456	Drosophila melanogaster	34%	70%
P48457	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	79%
P48460	Caenorhabditis elegans	33%	95%
P48463	Gallus gallus	36%	100%
P48483	Arabidopsis thaliana	35%	100%
P48488	Medicago sativa subsp. varia	36%	100%
P48528	Arabidopsis thaliana	38%	100%
P48529	Arabidopsis thaliana	36%	100%
P48577	Acetabularia peniculus	35%	100%
P48578	Arabidopsis thaliana	34%	100%
P48579	Helianthus annuus	36%	100%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	36%	100%
P49576	Paramecium tetraurelia	34%	100%
P53041	Homo sapiens	34%	87%
P53042	Rattus norvegicus	33%	87%
P53043	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	84%
P60510	Homo sapiens	36%	100%
P62714	Homo sapiens	35%	100%
P62715	Mus musculus	35%	100%
P62716	Rattus norvegicus	35%	100%
P63328	Mus musculus	32%	83%
P63329	Rattus norvegicus	32%	83%
P63330	Mus musculus	35%	100%
P63331	Rattus norvegicus	35%	100%
P67774	Bos taurus	35%	100%
P67775	Homo sapiens	35%	100%
P67776	Sus scrofa	35%	100%
P67777	Oryctolagus cuniculus	35%	100%
P97470	Mus musculus	36%	100%
Q05681	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	78%
Q06009	Medicago sativa	34%	100%
Q07098	Arabidopsis thaliana	36%	100%
Q07099	Arabidopsis thaliana	37%	100%
Q07100	Arabidopsis thaliana	34%	100%
Q08209	Homo sapiens	32%	83%
Q09496	Caenorhabditis elegans	33%	100%
Q0DBD3	Oryza sativa subsp. japonica	38%	100%
Q0E2S4	Oryza sativa subsp. japonica	38%	100%
Q0G819	Caenorhabditis elegans	31%	80%
Q0P594	Bos taurus	35%	100%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
Q10BT5	Oryza sativa subsp. japonica	35%	100%
Q12705	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	78%
Q27884	Drosophila melanogaster	35%	100%
Q3SWT6	Rattus norvegicus	26%	68%
Q4Q1M5	Leishmania major	30%	100%
Q4Q2C2	Leishmania major	37%	100%
Q4Q3C0	Leishmania major	35%	100%
Q4Q3C5	Leishmania major	31%	100%
Q4Q3C6	Leishmania major	32%	100%
Q4Q3C7	Leishmania major	33%	100%
Q4Q3C8	Leishmania major	33%	100%
Q4Q4W8	Leishmania major	41%	100%
Q4Q5Z8	Leishmania major	34%	100%
Q4Q7Z5	Leishmania major	34%	100%
Q4Q8K1	Leishmania major	35%	100%
Q4Q8T8	Leishmania major	31%	87%
Q4Q9W1	Leishmania major	36%	100%
Q4QFG0	Leishmania major	33%	100%
Q4QFZ7	Leishmania major	78%	74%
Q4QHX7	Leishmania major	33%	66%
Q4QJJ3	Leishmania major	32%	68%
Q4WUR1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	81%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	34%	100%
Q5BJ92	Rattus norvegicus	36%	100%
Q5R6K8	Pongo abelii	36%	100%
Q60676	Mus musculus	33%	87%
Q64620	Rattus norvegicus	35%	100%
Q6BFF6	Paramecium tetraurelia	34%	100%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	36%	100%
Q6IP91	Xenopus laevis	36%	100%
Q6P861	Xenopus tropicalis	36%	100%
Q7YSW8	Dictyostelium discoideum	34%	70%
Q84K11	Solanum lycopersicum	33%	78%
Q84XU2	Arabidopsis thaliana	33%	80%
Q8X178	Blumeria hordei	35%	100%
Q9CQR6	Mus musculus	35%	100%
Q9FN02	Arabidopsis thaliana	32%	100%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	100%
Q9LEV0	Arabidopsis thaliana	29%	72%
Q9LHE7	Arabidopsis thaliana	32%	100%
Q9SX52	Arabidopsis thaliana	33%	100%
Q9U9A3	Dictyostelium discoideum	32%	100%
Q9VXF1	Drosophila melanogaster	32%	74%
Q9XGH7	Nicotiana tabacum	35%	100%
Q9XTT8	Caenorhabditis elegans	35%	100%
Q9XW79	Caenorhabditis elegans	37%	100%
Q9XZE5	Dictyostelium discoideum	34%	100%
Q9Y0B7	Dictyostelium discoideum	35%	100%
Q9ZSE4	Hevea brasiliensis	38%	100%
V5B3V2	Trypanosoma cruzi	31%	100%
V5B5K9	Trypanosoma cruzi	36%	100%
V5B8G5	Trypanosoma cruzi	37%	100%
V5BAC7	Trypanosoma cruzi	33%	68%
V5BBR3	Trypanosoma cruzi	30%	100%
V5BBS3	Trypanosoma cruzi	32%	72%
V5BGM0	Trypanosoma cruzi	31%	100%
V5BQD7	Trypanosoma cruzi	43%	99%
V5D2G9	Trypanosoma cruzi	34%	100%
V5D5S2	Trypanosoma cruzi	29%	92%
V5DCW3	Trypanosoma cruzi	35%	100%
V5DIG8	Trypanosoma cruzi	44%	100%