LeishMANIAdb
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Phospholipid-transporting ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phospholipid-transporting ATPase
Gene product:
phospholipid-transporting ATPase 1-like protein
Species:
Leishmania major
UniProt:
Q4QG01_LEIMA
TriTrypDb:
LmjF.13.1530 , LMJLV39_130020000 * , LMJSD75_130020000 *
Length:
1097

Annotations

LeishMANIAdb annotations

Homologous to endosomal / ER-localized phospholipid flippases of other Eukaryotes.. These genes only duplicated in Trypasoma conorini and Trypansoma cruzi. Localization: ER (by homology) / Endosomal (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 6
Silverman et al. no yes: 0
Pissara et al. yes yes: 4
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 13
NetGPI no yes: 0, no: 13
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 2
GO:0005886 plasma membrane 3 2
GO:0016020 membrane 2 14
GO:0110165 cellular anatomical entity 1 14

Expansion

Sequence features

Q4QG01
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QG01

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 13
GO:0006869 lipid transport 5 13
GO:0009987 cellular process 1 2
GO:0015748 organophosphate ester transport 5 13
GO:0015914 phospholipid transport 6 13
GO:0016043 cellular component organization 3 2
GO:0034204 lipid translocation 4 2
GO:0045332 phospholipid translocation 5 2
GO:0051179 localization 1 13
GO:0051234 establishment of localization 2 13
GO:0061024 membrane organization 4 2
GO:0065007 biological regulation 1 2
GO:0065008 regulation of biological quality 2 2
GO:0071702 organic substance transport 4 13
GO:0071840 cellular component organization or biogenesis 2 2
GO:0097035 regulation of membrane lipid distribution 3 2
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 14
GO:0000287 magnesium ion binding 5 13
GO:0003824 catalytic activity 1 13
GO:0005215 transporter activity 1 13
GO:0005319 lipid transporter activity 2 13
GO:0005488 binding 1 14
GO:0005524 ATP binding 5 13
GO:0016462 pyrophosphatase activity 5 13
GO:0016787 hydrolase activity 2 13
GO:0016817 hydrolase activity, acting on acid anhydrides 3 13
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 13
GO:0016887 ATP hydrolysis activity 7 13
GO:0017076 purine nucleotide binding 4 13
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 13
GO:0030554 adenyl nucleotide binding 5 13
GO:0032553 ribonucleotide binding 3 13
GO:0032555 purine ribonucleotide binding 4 13
GO:0032559 adenyl ribonucleotide binding 5 13
GO:0035639 purine ribonucleoside triphosphate binding 4 13
GO:0036094 small molecule binding 2 14
GO:0043167 ion binding 2 13
GO:0043168 anion binding 3 13
GO:0043169 cation binding 3 13
GO:0046872 metal ion binding 4 13
GO:0097159 organic cyclic compound binding 2 14
GO:0097367 carbohydrate derivative binding 2 13
GO:0140303 intramembrane lipid transporter activity 3 13
GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2 13
GO:0140657 ATP-dependent activity 1 13
GO:1901265 nucleoside phosphate binding 3 14
GO:1901363 heterocyclic compound binding 2 14

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 203 205 PF00675 0.259
CLV_NRD_NRD_1 296 298 PF00675 0.304
CLV_NRD_NRD_1 340 342 PF00675 0.445
CLV_NRD_NRD_1 452 454 PF00675 0.449
CLV_NRD_NRD_1 528 530 PF00675 0.306
CLV_NRD_NRD_1 543 545 PF00675 0.220
CLV_NRD_NRD_1 611 613 PF00675 0.430
CLV_NRD_NRD_1 743 745 PF00675 0.369
CLV_NRD_NRD_1 8 10 PF00675 0.539
CLV_PCSK_KEX2_1 10 12 PF00082 0.384
CLV_PCSK_KEX2_1 128 130 PF00082 0.356
CLV_PCSK_KEX2_1 203 205 PF00082 0.283
CLV_PCSK_KEX2_1 611 613 PF00082 0.430
CLV_PCSK_KEX2_1 683 685 PF00082 0.334
CLV_PCSK_KEX2_1 743 745 PF00082 0.354
CLV_PCSK_PC1ET2_1 10 12 PF00082 0.377
CLV_PCSK_PC1ET2_1 128 130 PF00082 0.453
CLV_PCSK_PC1ET2_1 683 685 PF00082 0.334
CLV_PCSK_PC7_1 607 613 PF00082 0.255
CLV_PCSK_SKI1_1 1075 1079 PF00082 0.283
CLV_PCSK_SKI1_1 203 207 PF00082 0.251
CLV_PCSK_SKI1_1 283 287 PF00082 0.299
CLV_PCSK_SKI1_1 342 346 PF00082 0.440
CLV_PCSK_SKI1_1 413 417 PF00082 0.275
CLV_PCSK_SKI1_1 518 522 PF00082 0.319
CLV_PCSK_SKI1_1 557 561 PF00082 0.304
CLV_PCSK_SKI1_1 600 604 PF00082 0.319
CLV_PCSK_SKI1_1 607 611 PF00082 0.309
CLV_PCSK_SKI1_1 798 802 PF00082 0.288
CLV_PCSK_SKI1_1 869 873 PF00082 0.428
CLV_PCSK_SKI1_1 997 1001 PF00082 0.392
DEG_Nend_UBRbox_1 1 4 PF02207 0.578
DEG_ODPH_VHL_1 108 119 PF01847 0.356
DEG_SPOP_SBC_1 691 695 PF00917 0.549
DOC_CDC14_PxL_1 961 969 PF14671 0.358
DOC_CKS1_1 930 935 PF01111 0.558
DOC_CYCLIN_RxL_1 1072 1080 PF00134 0.475
DOC_CYCLIN_yClb5_NLxxxL_5 1075 1081 PF00134 0.437
DOC_CYCLIN_yClb5_NLxxxL_5 291 299 PF00134 0.558
DOC_CYCLIN_yCln2_LP_2 436 442 PF00134 0.513
DOC_CYCLIN_yCln2_LP_2 930 936 PF00134 0.479
DOC_MAPK_FxFP_2 53 56 PF00069 0.558
DOC_MAPK_gen_1 327 336 PF00069 0.501
DOC_MAPK_gen_1 515 524 PF00069 0.461
DOC_MAPK_gen_1 544 551 PF00069 0.449
DOC_MAPK_gen_1 61 70 PF00069 0.501
DOC_MAPK_gen_1 683 690 PF00069 0.530
DOC_MAPK_gen_1 741 749 PF00069 0.561
DOC_MAPK_gen_1 80 87 PF00069 0.593
DOC_MAPK_gen_1 814 822 PF00069 0.479
DOC_MAPK_HePTP_8 512 524 PF00069 0.449
DOC_MAPK_MEF2A_6 327 336 PF00069 0.562
DOC_MAPK_MEF2A_6 515 524 PF00069 0.449
DOC_MAPK_MEF2A_6 544 551 PF00069 0.458
DOC_MAPK_MEF2A_6 814 822 PF00069 0.479
DOC_MAPK_MEF2A_6 858 867 PF00069 0.483
DOC_PP4_FxxP_1 360 363 PF00568 0.417
DOC_PP4_FxxP_1 53 56 PF00568 0.556
DOC_USP7_MATH_1 1029 1033 PF00917 0.325
DOC_USP7_MATH_1 104 108 PF00917 0.338
DOC_USP7_MATH_1 290 294 PF00917 0.482
DOC_USP7_MATH_1 400 404 PF00917 0.524
DOC_USP7_MATH_1 624 628 PF00917 0.671
DOC_USP7_MATH_1 691 695 PF00917 0.535
DOC_USP7_UBL2_3 737 741 PF12436 0.723
DOC_USP7_UBL2_3 794 798 PF12436 0.616
DOC_WW_Pin1_4 328 333 PF00397 0.451
DOC_WW_Pin1_4 492 497 PF00397 0.464
DOC_WW_Pin1_4 538 543 PF00397 0.458
DOC_WW_Pin1_4 63 68 PF00397 0.394
DOC_WW_Pin1_4 778 783 PF00397 0.516
DOC_WW_Pin1_4 929 934 PF00397 0.520
DOC_WW_Pin1_4 97 102 PF00397 0.287
LIG_14-3-3_CanoR_1 263 271 PF00244 0.471
LIG_14-3-3_CanoR_1 350 355 PF00244 0.533
LIG_14-3-3_CanoR_1 413 423 PF00244 0.492
LIG_14-3-3_CanoR_1 743 748 PF00244 0.514
LIG_14-3-3_CanoR_1 853 857 PF00244 0.475
LIG_14-3-3_CanoR_1 858 867 PF00244 0.476
LIG_Actin_WH2_2 249 265 PF00022 0.458
LIG_Actin_WH2_2 723 739 PF00022 0.576
LIG_Actin_WH2_2 751 769 PF00022 0.601
LIG_AP2alpha_2 615 617 PF02296 0.546
LIG_APCC_ABBA_1 477 482 PF00400 0.500
LIG_BIR_III_4 434 438 PF00653 0.590
LIG_BRCT_BRCA1_1 21 25 PF00533 0.733
LIG_deltaCOP1_diTrp_1 266 269 PF00928 0.469
LIG_deltaCOP1_diTrp_1 615 621 PF00928 0.525
LIG_deltaCOP1_diTrp_1 893 899 PF00928 0.269
LIG_DLG_GKlike_1 350 357 PF00625 0.562
LIG_EH1_1 300 308 PF00400 0.501
LIG_eIF4E_1 1041 1047 PF01652 0.372
LIG_eIF4E_1 1052 1058 PF01652 0.372
LIG_FHA_1 1012 1018 PF00498 0.286
LIG_FHA_1 1060 1066 PF00498 0.433
LIG_FHA_1 189 195 PF00498 0.457
LIG_FHA_1 207 213 PF00498 0.408
LIG_FHA_1 220 226 PF00498 0.458
LIG_FHA_1 263 269 PF00498 0.463
LIG_FHA_1 329 335 PF00498 0.581
LIG_FHA_1 367 373 PF00498 0.515
LIG_FHA_1 400 406 PF00498 0.508
LIG_FHA_1 418 424 PF00498 0.386
LIG_FHA_1 482 488 PF00498 0.561
LIG_FHA_1 515 521 PF00498 0.486
LIG_FHA_1 526 532 PF00498 0.453
LIG_FHA_1 554 560 PF00498 0.533
LIG_FHA_1 599 605 PF00498 0.531
LIG_FHA_1 691 697 PF00498 0.505
LIG_FHA_1 744 750 PF00498 0.496
LIG_FHA_1 870 876 PF00498 0.358
LIG_FHA_1 953 959 PF00498 0.375
LIG_FHA_1 980 986 PF00498 0.298
LIG_FHA_2 1078 1084 PF00498 0.522
LIG_FHA_2 420 426 PF00498 0.488
LIG_FHA_2 650 656 PF00498 0.503
LIG_FHA_2 693 699 PF00498 0.586
LIG_FHA_2 737 743 PF00498 0.619
LIG_FHA_2 888 894 PF00498 0.283
LIG_FHA_2 976 982 PF00498 0.273
LIG_LIR_Apic_2 359 363 PF02991 0.468
LIG_LIR_Apic_2 835 839 PF02991 0.459
LIG_LIR_Gen_1 1016 1026 PF02991 0.325
LIG_LIR_Gen_1 22 32 PF02991 0.624
LIG_LIR_Gen_1 330 340 PF02991 0.558
LIG_LIR_Gen_1 353 363 PF02991 0.479
LIG_LIR_Gen_1 365 375 PF02991 0.495
LIG_LIR_Gen_1 384 391 PF02991 0.503
LIG_LIR_Gen_1 466 473 PF02991 0.493
LIG_LIR_Gen_1 759 768 PF02991 0.515
LIG_LIR_Gen_1 898 908 PF02991 0.299
LIG_LIR_Nem_3 1016 1021 PF02991 0.325
LIG_LIR_Nem_3 1049 1055 PF02991 0.302
LIG_LIR_Nem_3 22 28 PF02991 0.624
LIG_LIR_Nem_3 236 240 PF02991 0.562
LIG_LIR_Nem_3 266 272 PF02991 0.459
LIG_LIR_Nem_3 279 285 PF02991 0.424
LIG_LIR_Nem_3 330 336 PF02991 0.513
LIG_LIR_Nem_3 353 358 PF02991 0.508
LIG_LIR_Nem_3 365 370 PF02991 0.509
LIG_LIR_Nem_3 466 471 PF02991 0.511
LIG_LIR_Nem_3 62 68 PF02991 0.453
LIG_LIR_Nem_3 69 73 PF02991 0.444
LIG_LIR_Nem_3 759 765 PF02991 0.510
LIG_LIR_Nem_3 78 82 PF02991 0.435
LIG_LIR_Nem_3 898 903 PF02991 0.328
LIG_LIR_Nem_3 938 942 PF02991 0.520
LIG_LIR_Nem_3 984 990 PF02991 0.395
LIG_LYPXL_SIV_4 273 281 PF13949 0.451
LIG_LYPXL_yS_3 964 967 PF13949 0.358
LIG_NRBOX 1018 1024 PF00104 0.462
LIG_NRBOX 598 604 PF00104 0.518
LIG_NRBOX 941 947 PF00104 0.588
LIG_PALB2_WD40_1 1049 1057 PF16756 0.339
LIG_PCNA_yPIPBox_3 135 144 PF02747 0.609
LIG_PCNA_yPIPBox_3 408 419 PF02747 0.489
LIG_PCNA_yPIPBox_3 755 767 PF02747 0.587
LIG_PDZ_Class_3 1092 1097 PF00595 0.704
LIG_Pex14_1 1007 1011 PF04695 0.451
LIG_Pex14_1 347 351 PF04695 0.503
LIG_Pex14_1 617 621 PF04695 0.521
LIG_Pex14_1 895 899 PF04695 0.314
LIG_Pex14_2 1020 1024 PF04695 0.452
LIG_Pex14_2 1054 1058 PF04695 0.358
LIG_Pex14_2 336 340 PF04695 0.586
LIG_Pex14_2 878 882 PF04695 0.357
LIG_Pex14_2 911 915 PF04695 0.287
LIG_PTB_Apo_2 81 88 PF02174 0.286
LIG_SH2_CRK 1027 1031 PF00017 0.358
LIG_SH2_CRK 349 353 PF00017 0.555
LIG_SH2_CRK 510 514 PF00017 0.451
LIG_SH2_CRK 532 536 PF00017 0.501
LIG_SH2_CRK 65 69 PF00017 0.486
LIG_SH2_CRK 836 840 PF00017 0.468
LIG_SH2_CRK 900 904 PF00017 0.392
LIG_SH2_CRK 931 935 PF00017 0.501
LIG_SH2_GRB2like 390 393 PF00017 0.544
LIG_SH2_GRB2like 43 46 PF00017 0.558
LIG_SH2_GRB2like 939 942 PF00017 0.483
LIG_SH2_NCK_1 1027 1031 PF00017 0.392
LIG_SH2_SRC 836 839 PF00017 0.458
LIG_SH2_STAT3 1089 1092 PF00017 0.621
LIG_SH2_STAT3 761 764 PF00017 0.559
LIG_SH2_STAT5 1059 1062 PF00017 0.375
LIG_SH2_STAT5 301 304 PF00017 0.563
LIG_SH2_STAT5 333 336 PF00017 0.488
LIG_SH2_STAT5 351 354 PF00017 0.456
LIG_SH2_STAT5 385 388 PF00017 0.507
LIG_SH2_STAT5 43 46 PF00017 0.529
LIG_SH2_STAT5 467 470 PF00017 0.517
LIG_SH2_STAT5 65 68 PF00017 0.446
LIG_SH2_STAT5 761 764 PF00017 0.584
LIG_SH2_STAT5 86 89 PF00017 0.298
LIG_SH2_STAT5 883 886 PF00017 0.364
LIG_SH2_STAT5 931 934 PF00017 0.490
LIG_SH2_STAT5 939 942 PF00017 0.437
LIG_SH2_STAT5 977 980 PF00017 0.325
LIG_SH3_3 284 290 PF00018 0.451
LIG_SH3_3 584 590 PF00018 0.539
LIG_SH3_3 711 717 PF00018 0.654
LIG_SH3_3 98 104 PF00018 0.286
LIG_SUMO_SIM_anti_2 1062 1069 PF11976 0.358
LIG_SUMO_SIM_anti_2 174 181 PF11976 0.465
LIG_SUMO_SIM_anti_2 497 504 PF11976 0.446
LIG_SUMO_SIM_anti_2 519 524 PF11976 0.586
LIG_SUMO_SIM_anti_2 726 731 PF11976 0.613
LIG_SUMO_SIM_anti_2 872 877 PF11976 0.328
LIG_SUMO_SIM_anti_2 988 994 PF11976 0.358
LIG_SUMO_SIM_par_1 1062 1069 PF11976 0.239
LIG_SUMO_SIM_par_1 174 181 PF11976 0.523
LIG_SUMO_SIM_par_1 519 526 PF11976 0.456
LIG_SUMO_SIM_par_1 745 750 PF11976 0.533
LIG_TRAF2_1 181 184 PF00917 0.517
LIG_TRAF2_1 463 466 PF00917 0.498
LIG_TRFH_1 93 97 PF08558 0.356
LIG_TYR_ITIM 1025 1030 PF00017 0.438
LIG_TYR_ITIM 272 277 PF00017 0.333
LIG_TYR_ITIM 299 304 PF00017 0.438
LIG_TYR_ITIM 352 357 PF00017 0.325
LIG_TYR_ITIM 508 513 PF00017 0.288
LIG_UBA3_1 115 121 PF00899 0.288
LIG_UBA3_1 281 288 PF00899 0.286
LIG_UBA3_1 366 374 PF00899 0.341
LIG_UBA3_1 675 683 PF00899 0.482
LIG_WRC_WIRS_1 1070 1075 PF05994 0.268
LIG_WRC_WIRS_1 357 362 PF05994 0.413
LIG_WRC_WIRS_1 864 869 PF05994 0.328
LIG_WRC_WIRS_1 896 901 PF05994 0.351
MOD_CDK_SPxK_1 538 544 PF00069 0.298
MOD_CDK_SPxxK_3 538 545 PF00069 0.298
MOD_CDK_SPxxK_3 778 785 PF00069 0.367
MOD_CK1_1 100 106 PF00069 0.308
MOD_CK1_1 1032 1038 PF00069 0.338
MOD_CK1_1 1069 1075 PF00069 0.293
MOD_CK1_1 151 157 PF00069 0.441
MOD_CK1_1 417 423 PF00069 0.356
MOD_CK1_1 63 69 PF00069 0.358
MOD_CK1_1 887 893 PF00069 0.316
MOD_CK1_1 952 958 PF00069 0.444
MOD_CK2_1 177 183 PF00069 0.322
MOD_CK2_1 419 425 PF00069 0.343
MOD_CK2_1 492 498 PF00069 0.286
MOD_CK2_1 649 655 PF00069 0.357
MOD_CK2_1 736 742 PF00069 0.562
MOD_CK2_1 932 938 PF00069 0.438
MOD_CK2_1 975 981 PF00069 0.428
MOD_GlcNHglycan 1027 1030 PF01048 0.365
MOD_GlcNHglycan 209 212 PF01048 0.208
MOD_GlcNHglycan 28 31 PF01048 0.625
MOD_GlcNHglycan 596 599 PF01048 0.519
MOD_GlcNHglycan 773 776 PF01048 0.324
MOD_GlcNHglycan 886 889 PF01048 0.337
MOD_GlcNHglycan 987 990 PF01048 0.413
MOD_GSK3_1 100 107 PF00069 0.477
MOD_GSK3_1 1025 1032 PF00069 0.400
MOD_GSK3_1 11 18 PF00069 0.553
MOD_GSK3_1 362 369 PF00069 0.326
MOD_GSK3_1 417 424 PF00069 0.322
MOD_GSK3_1 514 521 PF00069 0.357
MOD_GSK3_1 534 541 PF00069 0.274
MOD_GSK3_1 553 560 PF00069 0.417
MOD_GSK3_1 589 596 PF00069 0.459
MOD_GSK3_1 59 66 PF00069 0.286
MOD_GSK3_1 686 693 PF00069 0.392
MOD_GSK3_1 792 799 PF00069 0.423
MOD_GSK3_1 975 982 PF00069 0.303
MOD_N-GLC_1 219 224 PF02516 0.477
MOD_N-GLC_1 400 405 PF02516 0.380
MOD_N-GLC_1 513 518 PF02516 0.408
MOD_N-GLC_1 629 634 PF02516 0.494
MOD_N-GLC_1 858 863 PF02516 0.358
MOD_N-GLC_1 869 874 PF02516 0.358
MOD_NEK2_1 1011 1016 PF00069 0.323
MOD_NEK2_1 1025 1030 PF00069 0.247
MOD_NEK2_1 1034 1039 PF00069 0.278
MOD_NEK2_1 1046 1051 PF00069 0.375
MOD_NEK2_1 188 193 PF00069 0.300
MOD_NEK2_1 206 211 PF00069 0.298
MOD_NEK2_1 21 26 PF00069 0.530
MOD_NEK2_1 219 224 PF00069 0.352
MOD_NEK2_1 225 230 PF00069 0.308
MOD_NEK2_1 473 478 PF00069 0.336
MOD_NEK2_1 501 506 PF00069 0.347
MOD_NEK2_1 59 64 PF00069 0.314
MOD_NEK2_1 594 599 PF00069 0.454
MOD_NEK2_1 736 741 PF00069 0.519
MOD_NEK2_1 792 797 PF00069 0.411
MOD_NEK2_1 902 907 PF00069 0.358
MOD_NEK2_1 949 954 PF00069 0.402
MOD_NEK2_1 985 990 PF00069 0.332
MOD_NEK2_2 624 629 PF00069 0.577
MOD_NEK2_2 852 857 PF00069 0.438
MOD_NEK2_2 895 900 PF00069 0.295
MOD_PK_1 135 141 PF00069 0.436
MOD_PK_1 545 551 PF00069 0.298
MOD_PKA_1 557 563 PF00069 0.338
MOD_PKA_1 683 689 PF00069 0.389
MOD_PKA_1 743 749 PF00069 0.420
MOD_PKA_1 80 86 PF00069 0.314
MOD_PKA_2 262 268 PF00069 0.312
MOD_PKA_2 514 520 PF00069 0.302
MOD_PKA_2 60 66 PF00069 0.356
MOD_PKA_2 630 636 PF00069 0.527
MOD_PKA_2 683 689 PF00069 0.389
MOD_PKA_2 743 749 PF00069 0.370
MOD_PKA_2 766 772 PF00069 0.447
MOD_PKA_2 852 858 PF00069 0.314
MOD_PKA_2 975 981 PF00069 0.333
MOD_PKB_1 9 17 PF00069 0.460
MOD_Plk_1 219 225 PF00069 0.414
MOD_Plk_1 342 348 PF00069 0.367
MOD_Plk_1 808 814 PF00069 0.373
MOD_Plk_1 858 864 PF00069 0.358
MOD_Plk_1 869 875 PF00069 0.358
MOD_Plk_4 1013 1019 PF00069 0.370
MOD_Plk_4 1029 1035 PF00069 0.301
MOD_Plk_4 1066 1072 PF00069 0.271
MOD_Plk_4 135 141 PF00069 0.504
MOD_Plk_4 350 356 PF00069 0.342
MOD_Plk_4 545 551 PF00069 0.298
MOD_Plk_4 565 571 PF00069 0.158
MOD_Plk_4 66 72 PF00069 0.287
MOD_Plk_4 743 749 PF00069 0.347
MOD_Plk_4 784 790 PF00069 0.495
MOD_Plk_4 808 814 PF00069 0.373
MOD_Plk_4 852 858 PF00069 0.307
MOD_Plk_4 871 877 PF00069 0.225
MOD_Plk_4 887 893 PF00069 0.238
MOD_Plk_4 895 901 PF00069 0.300
MOD_Plk_4 941 947 PF00069 0.392
MOD_Plk_4 949 955 PF00069 0.308
MOD_Plk_4 963 969 PF00069 0.334
MOD_Plk_4 981 987 PF00069 0.176
MOD_ProDKin_1 328 334 PF00069 0.288
MOD_ProDKin_1 492 498 PF00069 0.307
MOD_ProDKin_1 538 544 PF00069 0.298
MOD_ProDKin_1 63 69 PF00069 0.208
MOD_ProDKin_1 778 784 PF00069 0.373
MOD_ProDKin_1 929 935 PF00069 0.384
MOD_ProDKin_1 97 103 PF00069 0.287
MOD_SUMO_for_1 480 483 PF00179 0.333
MOD_SUMO_rev_2 292 299 PF00179 0.302
MOD_SUMO_rev_2 455 461 PF00179 0.515
MOD_SUMO_rev_2 539 547 PF00179 0.314
MOD_SUMO_rev_2 552 559 PF00179 0.298
MOD_SUMO_rev_2 715 720 PF00179 0.519
MOD_SUMO_rev_2 74 82 PF00179 0.268
TRG_DiLeu_BaEn_1 981 986 PF01217 0.288
TRG_DiLeu_BaEn_3 183 189 PF01217 0.392
TRG_DiLeu_BaLyEn_6 508 513 PF01217 0.296
TRG_ENDOCYTIC_2 1027 1030 PF00928 0.335
TRG_ENDOCYTIC_2 1041 1044 PF00928 0.298
TRG_ENDOCYTIC_2 1052 1055 PF00928 0.305
TRG_ENDOCYTIC_2 274 277 PF00928 0.314
TRG_ENDOCYTIC_2 301 304 PF00928 0.438
TRG_ENDOCYTIC_2 333 336 PF00928 0.431
TRG_ENDOCYTIC_2 349 352 PF00928 0.356
TRG_ENDOCYTIC_2 354 357 PF00928 0.351
TRG_ENDOCYTIC_2 385 388 PF00928 0.461
TRG_ENDOCYTIC_2 510 513 PF00928 0.288
TRG_ENDOCYTIC_2 532 535 PF00928 0.314
TRG_ENDOCYTIC_2 65 68 PF00928 0.314
TRG_ENDOCYTIC_2 854 857 PF00928 0.309
TRG_ENDOCYTIC_2 86 89 PF00928 0.298
TRG_ENDOCYTIC_2 883 886 PF00928 0.376
TRG_ENDOCYTIC_2 900 903 PF00928 0.298
TRG_ENDOCYTIC_2 931 934 PF00928 0.347
TRG_ENDOCYTIC_2 939 942 PF00928 0.278
TRG_ENDOCYTIC_2 964 967 PF00928 0.343
TRG_ER_diArg_1 8 11 PF00400 0.478
TRG_NLS_MonoExtC_3 8 13 PF00514 0.466
TRG_NLS_MonoExtN_4 6 13 PF00514 0.463
TRG_Pf-PMV_PEXEL_1 917 921 PF00026 0.392
TRG_Pf-PMV_PEXEL_1 997 1001 PF00026 0.268

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P450 Leptomonas seymouri 30% 93%
A0A0N1I0X4 Leptomonas seymouri 70% 100%
A0A0N1PF54 Leptomonas seymouri 28% 84%
A0A0S4IM76 Bodo saltans 30% 100%
A0A0S4ITW3 Bodo saltans 25% 79%
A0A0S4J0T6 Bodo saltans 30% 85%
A0A0S4JDQ9 Bodo saltans 38% 98%
A0A0S4JP22 Bodo saltans 32% 88%
A0A0S4JUG6 Bodo saltans 55% 100%
A0A1X0NJY2 Trypanosomatidae 58% 100%
A0A1X0NNY6 Trypanosomatidae 23% 100%
A0A1X0P1Z0 Trypanosomatidae 26% 91%
A0A1X0PAR5 Trypanosomatidae 32% 100%
A0A3Q8IFQ5 Leishmania donovani 27% 86%
A0A3Q8INM6 Leishmania donovani 29% 95%
A0A3R7P4C4 Trypanosoma rangeli 54% 100%
A0A3S5IS27 Trypanosoma rangeli 27% 90%
A0A422NNI9 Trypanosoma rangeli 31% 100%
A0A422NTS7 Trypanosoma rangeli 22% 100%
A0A451EJU6 Leishmania donovani 22% 100%
A1A4J6 Bos taurus 31% 97%
A3FIN4 Mus musculus 33% 93%
A4H7E2 Leishmania braziliensis 78% 100%
A4H7E4 Leishmania braziliensis 80% 100%
A4HIF8 Leishmania braziliensis 28% 88%
A4HRZ6 Leishmania infantum 22% 100%
A4HVT2 Leishmania infantum 94% 100%
A4I5Q4 Leishmania infantum 27% 86%
A4IA89 Leishmania infantum 29% 95%
C7EXK4 Bos taurus 35% 96%
C9ZM06 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZR23 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 92%
D0A6F9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 52% 97%
D4AA47 Rattus norvegicus 32% 88%
D4ABB8 Rattus norvegicus 30% 96%
E9APH7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 99%
E9B0Z9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 86%
E9B5B1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 95%
F1Q4S1 Danio rerio 31% 98%
G5E829 Mus musculus 23% 90%
G5EBH1 Caenorhabditis elegans 31% 100%
O23087 Arabidopsis thaliana 22% 100%
O36028 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 31% 80%
O43520 Homo sapiens 32% 88%
O43861 Homo sapiens 30% 96%
O60423 Homo sapiens 28% 84%
O70228 Mus musculus 30% 100%
O75110 Homo sapiens 29% 100%
O94296 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 33% 87%
P04191 Oryctolagus cuniculus 22% 100%
P11505 Rattus norvegicus 23% 90%
P32660 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 70%
P39524 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 81%
P40527 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 95%
P54209 Dunaliella bioculata 23% 100%
P54678 Dictyostelium discoideum 21% 98%
P57792 Arabidopsis thaliana 33% 93%
P70704 Mus musculus 34% 94%
P98195 Mus musculus 30% 96%
P98196 Homo sapiens 31% 97%
P98197 Mus musculus 30% 92%
P98198 Homo sapiens 34% 91%
P98199 Mus musculus 34% 91%
P98200 Mus musculus 35% 96%
P98204 Arabidopsis thaliana 31% 95%
P98205 Arabidopsis thaliana 32% 99%
Q09891 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 31% 78%
Q0VCY0 Bos taurus 22% 100%
Q10309 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 29% 100%
Q12675 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 68%
Q148W0 Mus musculus 32% 88%
Q29449 Bos taurus 34% 95%
Q4Q2M2 Leishmania major 30% 100%
Q4Q767 Leishmania major 28% 86%
Q5BL50 Xenopus tropicalis 32% 88%
Q64578 Rattus norvegicus 22% 100%
Q6DFW5 Mus musculus 33% 93%
Q6UQ17 Mus musculus 31% 82%
Q6VXY9 Leishmania donovani 94% 100%
Q8NB49 Homo sapiens 31% 97%
Q8R429 Mus musculus 22% 100%
Q8TF62 Homo sapiens 34% 92%
Q92105 Pelophylax lessonae 20% 100%
Q95Z93 Leishmania major 22% 100%
Q98SH2 Gallus gallus 22% 91%
Q9HDW7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 22% 85%
Q9LI83 Arabidopsis thaliana 33% 91%
Q9LK90 Arabidopsis thaliana 32% 92%
Q9LNQ4 Arabidopsis thaliana 32% 90%
Q9N0Z4 Oryctolagus cuniculus 33% 94%
Q9NTI2 Homo sapiens 36% 92%
Q9QZW0 Mus musculus 31% 97%
Q9SAF5 Arabidopsis thaliana 33% 91%
Q9SX33 Arabidopsis thaliana 32% 91%
Q9U280 Caenorhabditis elegans 35% 96%
Q9XES1 Arabidopsis thaliana 22% 100%
Q9XIE6 Arabidopsis thaliana 33% 90%
Q9Y2G3 Homo sapiens 33% 93%
Q9Y2Q0 Homo sapiens 34% 94%
V5BHI7 Trypanosoma cruzi 57% 100%
V5BLM1 Trypanosoma cruzi 22% 100%
V5BV40 Trypanosoma cruzi 31% 100%
V5DCY9 Trypanosoma cruzi 30% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS