J domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QFX6_LEIMA

TriTrypDb:

LmjF.14.0090 , LMJLV39_140005900 , LMJSD75_140005900

Length:

385

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QFX6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFX6

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	123	125	PF00675	0.774
CLV_NRD_NRD_1	163	165	PF00675	0.813
CLV_NRD_NRD_1	197	199	PF00675	0.677
CLV_NRD_NRD_1	207	209	PF00675	0.581
CLV_NRD_NRD_1	260	262	PF00675	0.661
CLV_NRD_NRD_1	347	349	PF00675	0.689
CLV_PCSK_KEX2_1	162	164	PF00082	0.839
CLV_PCSK_KEX2_1	197	199	PF00082	0.677
CLV_PCSK_KEX2_1	207	209	PF00082	0.581
CLV_PCSK_KEX2_1	259	261	PF00082	0.672

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB18	Leptomonas seymouri	50%	97%
A0A3S7WSS6	Leishmania donovani	94%	100%
A4H7H0	Leishmania braziliensis	73%	100%
A4HVV1	Leishmania infantum	94%	100%
E9APK3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%

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