Complex I-B14

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Complex I-B14

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QFS7_LEIMA

TriTrypDb:

LmjF.14.0580 , LMJLV39_140011700 , LMJSD75_140011300

Length:

126

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QFS7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFS7

PDB structure(s): 7am2_CD

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	39	41	PF00675	0.456
CLV_NRD_NRD_1	69	71	PF00675	0.403
CLV_NRD_NRD_1	88	90	PF00675	0.282
CLV_PCSK_KEX2_1	38	40	PF00082	0.461
CLV_PCSK_KEX2_1	69	71	PF00082	0.404
CLV_PCSK_KEX2_1	88	90	PF00082	0.416
CLV_PCSK_PC7_1	35	41	PF00082	0.430
CLV_PCSK_SKI1_1	69	73	PF00082	0.360
DOC_CYCLIN_RxL_1	66	74	PF00134	0.486
DOC_MAPK_gen_1	35	43	PF00069	0.534
DOC_MAPK_gen_1	88	97	PF00069	0.448
DOC_PP1_RVXF_1	105	112	PF00149	0.449
DOC_USP7_UBL2_3	73	77	PF12436	0.418
DOC_WW_Pin1_4	12	17	PF00397	0.566
DOC_WW_Pin1_4	3	8	PF00397	0.682
LIG_14-3-3_CanoR_1	100	109	PF00244	0.454
LIG_FHA_1	13	19	PF00498	0.618
LIG_FHA_1	76	82	PF00498	0.470
LIG_FHA_2	80	86	PF00498	0.507
LIG_LIR_LC3C_4	78	81	PF02991	0.499
LIG_LIR_Nem_3	74	79	PF02991	0.417
LIG_SH2_CRK	68	72	PF00017	0.388
LIG_SH2_CRK	76	80	PF00017	0.382
LIG_SH2_NCK_1	33	37	PF00017	0.561
LIG_SH2_STAP1	93	97	PF00017	0.418
LIG_SH2_STAT5	33	36	PF00017	0.564
LIG_SH3_3	53	59	PF00018	0.455
LIG_SUMO_SIM_par_1	77	83	PF11976	0.500
LIG_WW_1	30	33	PF00397	0.585
MOD_CDC14_SPxK_1	6	9	PF00782	0.535
MOD_CDK_SPxK_1	3	9	PF00069	0.537
MOD_CK1_1	99	105	PF00069	0.543
MOD_GSK3_1	75	82	PF00069	0.438
MOD_GSK3_1	95	102	PF00069	0.282
MOD_NEK2_1	95	100	PF00069	0.386
MOD_PIKK_1	48	54	PF00454	0.568
MOD_PK_1	14	20	PF00069	0.416
MOD_PKA_2	99	105	PF00069	0.460
MOD_Plk_4	14	20	PF00069	0.525
MOD_Plk_4	75	81	PF00069	0.406
MOD_ProDKin_1	12	18	PF00069	0.560
MOD_ProDKin_1	3	9	PF00069	0.684
TRG_DiLeu_BaLyEn_6	67	72	PF01217	0.425
TRG_ENDOCYTIC_2	68	71	PF00928	0.371
TRG_ENDOCYTIC_2	76	79	PF00928	0.354
TRG_ER_diArg_1	38	40	PF00400	0.463
TRG_ER_diArg_1	68	70	PF00400	0.417
TRG_ER_diArg_1	87	89	PF00400	0.399
TRG_NLS_MonoExtC_3	88	94	PF00514	0.389
TRG_NLS_MonoExtN_4	88	93	PF00514	0.501
TRG_Pf-PMV_PEXEL_1	69	74	PF00026	0.435

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCX7	Leptomonas seymouri	82%	100%
A0A0S4J267	Bodo saltans	59%	100%
A0A1X0NNN4	Trypanosomatidae	64%	100%
A0A3R7MRR7	Trypanosoma rangeli	64%	100%
A0A3S7WSX5	Leishmania donovani	97%	100%
A4H7L5	Leishmania braziliensis	93%	100%
A4HW00	Leishmania infantum	98%	100%
C9ZT21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	100%
E9APQ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%