zf-LSD1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

LSD1 zinc finger, putative

Species:

Leishmania major

UniProt:

Q4QFS2_LEIMA

TriTrypDb:

LmjF.14.0625 , LMJLV39_140012200 , LMJSD75_140011800

Length:

226

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7

Expansion

Sequence features

Q4QFS2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFS2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	121	123	PF00675	0.761
CLV_NRD_NRD_1	133	135	PF00675	0.589
CLV_NRD_NRD_1	141	143	PF00675	0.715
CLV_PCSK_KEX2_1	121	123	PF00082	0.761
CLV_PCSK_KEX2_1	132	134	PF00082	0.602
CLV_PCSK_KEX2_1	140	142	PF00082	0.722
CLV_PCSK_PC7_1	128	134	PF00082	0.655
CLV_PCSK_SKI1_1	13	17	PF00082	0.514
DEG_Nend_Nbox_1	1	3	PF02207	0.598
DOC_CYCLIN_yCln2_LP_2	15	21	PF00134	0.335
DOC_CYCLIN_yCln2_LP_2	73	76	PF00134	0.527
DOC_MAPK_MEF2A_6	214	221	PF00069	0.694
DOC_PP2B_LxvP_1	49	52	PF13499	0.412
DOC_PP2B_LxvP_1	73	76	PF13499	0.522
DOC_USP7_MATH_1	194	198	PF00917	0.738
DOC_USP7_MATH_1	76	80	PF00917	0.538
LIG_14-3-3_CanoR_1	13	18	PF00244	0.352
LIG_14-3-3_CanoR_1	133	139	PF00244	0.692
LIG_BIR_III_4	165	169	PF00653	0.676
LIG_BRCT_BRCA1_1	134	138	PF00533	0.653
LIG_EVH1_1	74	78	PF00568	0.527
LIG_FHA_1	113	119	PF00498	0.552
LIG_FHA_1	14	20	PF00498	0.453
LIG_FHA_1	216	222	PF00498	0.569
LIG_FHA_1	53	59	PF00498	0.596
LIG_FHA_1	87	93	PF00498	0.543
LIG_FHA_2	158	164	PF00498	0.658
LIG_FHA_2	63	69	PF00498	0.423
LIG_MYND_1	98	102	PF01753	0.717
LIG_RPA_C_Fungi	116	128	PF08784	0.550
LIG_SH2_STAT3	9	12	PF00017	0.335
LIG_SH2_STAT5	195	198	PF00017	0.754
LIG_SH2_STAT5	94	97	PF00017	0.597
LIG_SH3_2	98	103	PF14604	0.696
LIG_SH3_3	185	191	PF00018	0.671
LIG_SH3_3	197	203	PF00018	0.566
LIG_SH3_3	72	78	PF00018	0.540
LIG_SH3_3	92	98	PF00018	0.593
LIG_SUMO_SIM_anti_2	55	60	PF11976	0.539
LIG_SUMO_SIM_par_1	158	165	PF11976	0.572
LIG_SUMO_SIM_par_1	217	223	PF11976	0.569
LIG_TRAF2_1	144	147	PF00917	0.668
LIG_WW_2	75	78	PF00397	0.545
LIG_WW_3	100	104	PF00397	0.715
MOD_CK1_1	198	204	PF00069	0.702
MOD_CK1_1	96	102	PF00069	0.612
MOD_CK2_1	141	147	PF00069	0.762
MOD_Cter_Amidation	130	133	PF01082	0.652
MOD_GlcNHglycan	134	137	PF01048	0.675
MOD_GlcNHglycan	197	200	PF01048	0.745
MOD_GSK3_1	113	120	PF00069	0.760
MOD_GSK3_1	194	201	PF00069	0.753
MOD_N-GLC_1	112	117	PF02516	0.541
MOD_NEK2_1	112	117	PF00069	0.628
MOD_NEK2_1	220	225	PF00069	0.574
MOD_NEK2_2	20	25	PF00069	0.335
MOD_PIKK_1	122	128	PF00454	0.552
MOD_PKA_1	121	127	PF00069	0.742
MOD_PKA_1	132	138	PF00069	0.539
MOD_PKA_1	141	147	PF00069	0.683
MOD_PKA_2	121	127	PF00069	0.750
MOD_PKA_2	132	138	PF00069	0.530
MOD_PKA_2	141	147	PF00069	0.651
MOD_PKB_1	132	140	PF00069	0.713
MOD_PKB_1	25	33	PF00069	0.246
MOD_Plk_1	112	118	PF00069	0.553
MOD_Plk_1	157	163	PF00069	0.669
MOD_Plk_4	113	119	PF00069	0.584
MOD_Plk_4	157	163	PF00069	0.669
MOD_Plk_4	215	221	PF00069	0.571
TRG_ER_diArg_1	102	105	PF00400	0.679
TRG_ER_diArg_1	121	123	PF00400	0.704
TRG_ER_diArg_1	132	134	PF00400	0.567
TRG_ER_diArg_1	140	142	PF00400	0.689
TRG_ER_diArg_1	25	28	PF00400	0.472
TRG_Pf-PMV_PEXEL_1	121	126	PF00026	0.550

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4B1	Leptomonas seymouri	47%	100%
A0A3Q8IBZ4	Leishmania donovani	89%	100%
A4H7M0	Leishmania braziliensis	67%	100%
A4HW05	Leishmania infantum	90%	100%
E9APQ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%