LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QFN3_LEIMA
TriTrypDb:
LmjF.14.1020 , LMJLV39_140017000 * , LMJSD75_140016400 *
Length:
314

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QFN3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFN3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 120 122 PF00675 0.732
CLV_NRD_NRD_1 20 22 PF00675 0.597
CLV_NRD_NRD_1 204 206 PF00675 0.635
CLV_NRD_NRD_1 207 209 PF00675 0.642
CLV_NRD_NRD_1 273 275 PF00675 0.741
CLV_NRD_NRD_1 293 295 PF00675 0.681
CLV_PCSK_KEX2_1 126 128 PF00082 0.646
CLV_PCSK_KEX2_1 20 22 PF00082 0.597
CLV_PCSK_KEX2_1 293 295 PF00082 0.609
CLV_PCSK_PC1ET2_1 126 128 PF00082 0.646
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IIK5 Leptomonas seymouri 77% 100%
A0A0S4J633 Bodo saltans 40% 76%
A0A1X0NNI6 Trypanosomatidae 58% 96%
A0A3Q8ID70 Leishmania donovani 96% 100%
A0A422N494 Trypanosoma rangeli 59% 98%
A4H7Q5 Leishmania braziliensis 92% 94%
A4HW44 Leishmania infantum 96% 100%
C9ZSX7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 57% 98%
E9APU7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
V5BJ00 Trypanosoma cruzi 59% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS