Putative kinesin K39

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinesin K39, putative

Species:

Leishmania major

UniProt:

Q4QFM4_LEIMA

TriTrypDb:

LmjF.14.1100 , LMJLV39_000014400 , LMJLV39_140018500 , LMJSD75_140017900 , LMJSD75_140018000 , LMJSD75_140018100

Length:

2765

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0005576	extracellular region	2	1
GO:0005737	cytoplasm	2	2
GO:0005871	kinesin complex	3	2
GO:0005874	microtubule	6	2
GO:0005875	microtubule associated complex	2	2
GO:0032991	protein-containing complex	1	2
GO:0099080	supramolecular complex	2	2
GO:0099081	supramolecular polymer	3	2
GO:0099512	supramolecular fiber	4	2
GO:0099513	polymeric cytoskeletal fiber	5	2

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Expansion

Sequence features

Q4QFM4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006810	transport	3	1
GO:0006869	lipid transport	5	1
GO:0007017	microtubule-based process	2	9
GO:0007018	microtubule-based movement	3	9
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	9
GO:0019538	protein metabolic process	3	1
GO:0042157	lipoprotein metabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	9
GO:0003774	cytoskeletal motor activity	1	9
GO:0003777	microtubule motor activity	2	9
GO:0003824	catalytic activity	1	3
GO:0005488	binding	1	9
GO:0005515	protein binding	2	9
GO:0005524	ATP binding	5	9
GO:0008017	microtubule binding	5	9
GO:0008092	cytoskeletal protein binding	3	9
GO:0008289	lipid binding	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	83	87	PF00656	0.386
CLV_NRD_NRD_1	1227	1229	PF00675	0.445
CLV_NRD_NRD_1	1396	1398	PF00675	0.463
CLV_NRD_NRD_1	157	159	PF00675	0.386
CLV_NRD_NRD_1	1769	1771	PF00675	0.512
CLV_NRD_NRD_1	190	192	PF00675	0.379
CLV_NRD_NRD_1	2757	2759	PF00675	0.597
CLV_NRD_NRD_1	2762	2764	PF00675	0.444
CLV_NRD_NRD_1	405	407	PF00675	0.572
CLV_NRD_NRD_1	492	494	PF00675	0.545

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8I9Y0	Leishmania donovani	39%	81%
A0A3Q8IA13	Leishmania donovani	72%	78%
A4H7R4	Leishmania braziliensis	43%	100%
A4HW57	Leishmania infantum	64%	84%
A4HW58	Leishmania infantum	29%	94%
A4HX43	Leishmania infantum	27%	98%
C9ZSW6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	72%

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