Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QFG9_LEIMA

TriTrypDb:

LmjF.15.0150 , LMJLV39_150006600 , LMJSD75_150006700

Length:

182

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QFG9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFG9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	122	126	PF00656	0.780
DEG_SPOP_SBC_1	171	175	PF00917	0.680
DOC_CYCLIN_yCln2_LP_2	156	162	PF00134	0.689
DOC_PP2B_LxvP_1	156	159	PF13499	0.582
DOC_PP4_FxxP_1	141	144	PF00568	0.724
DOC_PP4_FxxP_1	96	99	PF00568	0.590
DOC_USP7_MATH_1	161	165	PF00917	0.665
DOC_USP7_MATH_1	169	173	PF00917	0.645
LIG_14-3-3_CanoR_1	65	69	PF00244	0.697
LIG_Actin_WH2_2	61	76	PF00022	0.743
LIG_BIR_II_1	1	5	PF00653	0.639
LIG_BIR_III_3	1	5	PF00653	0.678
LIG_FHA_1	112	118	PF00498	0.769
LIG_LIR_Apic_2	139	144	PF02991	0.723
LIG_LIR_Gen_1	143	154	PF02991	0.660
LIG_LIR_Gen_1	15	24	PF02991	0.568
LIG_LIR_Gen_1	26	35	PF02991	0.539
LIG_LIR_Nem_3	143	149	PF02991	0.661
LIG_LIR_Nem_3	15	20	PF02991	0.568
LIG_LIR_Nem_3	26	30	PF02991	0.530
LIG_SH2_PTP2	146	149	PF00017	0.726
LIG_SH2_STAT5	131	134	PF00017	0.622
LIG_SH2_STAT5	146	149	PF00017	0.632
LIG_SH2_STAT5	84	87	PF00017	0.501
LIG_SH3_2	69	74	PF14604	0.547
LIG_SH3_3	30	36	PF00018	0.521
LIG_SH3_3	66	72	PF00018	0.548
LIG_SH3_3	94	100	PF00018	0.499
LIG_TRFH_1	96	100	PF08558	0.593
LIG_WRC_WIRS_1	138	143	PF05994	0.730
LIG_WRC_WIRS_1	24	29	PF05994	0.699
MOD_CK1_1	116	122	PF00069	0.593
MOD_CK1_1	134	140	PF00069	0.581
MOD_CK1_1	164	170	PF00069	0.760
MOD_CK1_1	172	178	PF00069	0.651
MOD_CK1_1	49	55	PF00069	0.685
MOD_CK2_1	117	123	PF00069	0.685
MOD_CK2_1	137	143	PF00069	0.406
MOD_CK2_1	23	29	PF00069	0.683
MOD_CK2_1	38	44	PF00069	0.560
MOD_GlcNHglycan	119	122	PF01048	0.681
MOD_GSK3_1	113	120	PF00069	0.630
MOD_GSK3_1	127	134	PF00069	0.737
MOD_GSK3_1	163	170	PF00069	0.623
MOD_GSK3_1	171	178	PF00069	0.654
MOD_GSK3_1	34	41	PF00069	0.643
MOD_GSK3_1	45	52	PF00069	0.618
MOD_N-GLC_1	49	54	PF02516	0.667
MOD_NEK2_1	113	118	PF00069	0.586
MOD_NEK2_1	163	168	PF00069	0.625
MOD_NEK2_2	2	7	PF00069	0.671
MOD_PKA_2	64	70	PF00069	0.699
MOD_Plk_1	127	133	PF00069	0.551
MOD_Plk_4	23	29	PF00069	0.602
TRG_DiLeu_BaLyEn_6	97	102	PF01217	0.602
TRG_ENDOCYTIC_2	146	149	PF00928	0.726

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXC4	Leptomonas seymouri	39%	99%
A0A3Q8IDA8	Leishmania donovani	87%	100%
A4HWB2	Leishmania infantum	87%	100%
E9AQ12	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%