Cytochrome b5 heme-binding domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

cytochrome b5-like Heme/Steroid binding domain containing protein, putative

Species:

Leishmania major

UniProt:

Q4QFG4_LEIMA

TriTrypDb:

LmjF.15.0190 , LMJLV39_150007200 , LMJSD75_150007200

Length:

163


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005783	endoplasmic reticulum	5	2
GO:0012505	endomembrane system	2	2
GO:0016020	membrane	2	10
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	10

Q4QFG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFG4


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	46	48	PF00675	0.464
CLV_PCSK_KEX2_1	156	158	PF00082	0.307
CLV_PCSK_KEX2_1	46	48	PF00082	0.335
CLV_PCSK_PC1ET2_1	156	158	PF00082	0.306
CLV_PCSK_SKI1_1	10	14	PF00082	0.511
CLV_PCSK_SKI1_1	47	51	PF00082	0.351
DOC_MAPK_gen_1	66	75	PF00069	0.476
DOC_MAPK_MEF2A_6	66	75	PF00069	0.484
DOC_USP7_MATH_1	4	8	PF00917	0.535
DOC_USP7_UBL2_3	152	156	PF12436	0.553
LIG_14-3-3_CanoR_1	157	162	PF00244	0.599
LIG_14-3-3_CanoR_1	53	58	PF00244	0.485
LIG_BIR_II_1	1	5	PF00653	0.443
LIG_BIR_III_4	3	7	PF00653	0.348
LIG_deltaCOP1_diTrp_1	132	137	PF00928	0.485
LIG_FHA_2	127	133	PF00498	0.401
LIG_FHA_2	54	60	PF00498	0.427
LIG_LIR_Apic_2	83	89	PF02991	0.445
LIG_LIR_Gen_1	118	127	PF02991	0.416
LIG_LIR_Gen_1	90	97	PF02991	0.488
LIG_LIR_Nem_3	118	122	PF02991	0.406
LIG_LIR_Nem_3	139	144	PF02991	0.456
LIG_LIR_Nem_3	90	96	PF02991	0.477
LIG_LYPXL_yS_3	141	144	PF13949	0.480
LIG_Pex14_1	133	137	PF04695	0.464
LIG_SH2_STAP1	93	97	PF00017	0.522
LIG_SH2_STAT5	55	58	PF00017	0.456
LIG_SH3_3	86	92	PF00018	0.461
LIG_TRAF2_1	56	59	PF00917	0.422
LIG_UBA3_1	29	36	PF00899	0.421
MOD_CK1_1	2	8	PF00069	0.456
MOD_CK2_1	126	132	PF00069	0.461
MOD_CK2_1	53	59	PF00069	0.439
MOD_Cter_Amidation	64	67	PF01082	0.277
MOD_GlcNHglycan	6	9	PF01048	0.661
MOD_GlcNHglycan	93	96	PF01048	0.342
MOD_N-GLC_1	80	85	PF02516	0.273
MOD_Plk_1	117	123	PF00069	0.406
MOD_Plk_1	80	86	PF00069	0.501
MOD_Plk_4	13	19	PF00069	0.272
TRG_ENDOCYTIC_2	141	144	PF00928	0.437
TRG_ENDOCYTIC_2	93	96	PF00928	0.445
TRG_ER_diArg_1	45	47	PF00400	0.531
TRG_Pf-PMV_PEXEL_1	128	132	PF00026	0.250


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8C7	Leptomonas seymouri	38%	100%
A0A0N1I2M9	Leptomonas seymouri	67%	100%
A0A0S4IM89	Bodo saltans	39%	100%
A0A0S4KHZ8	Bodo saltans	52%	100%
A0A1X0NM31	Trypanosomatidae	35%	100%
A0A1X0NTL9	Trypanosomatidae	58%	100%
A0A3Q8IGX1	Leishmania donovani	41%	100%
A0A3R7L838	Trypanosoma rangeli	36%	100%
A0A3R7RC54	Trypanosoma rangeli	39%	91%
A0A3S7WTB2	Leishmania donovani	94%	100%
A0A422NSD0	Trypanosoma rangeli	54%	100%
A4H7Y9	Leishmania braziliensis	79%	100%
A4HB24	Leishmania braziliensis	39%	92%
A4HQJ0	Leishmania braziliensis	40%	100%
A4HWB7	Leishmania infantum	96%	100%
C9ZNV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
E9AHZ9	Leishmania infantum	41%	100%
E9AQ17	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
E9AUA3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
O13995	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	98%
Q7YZW5	Caenorhabditis elegans	32%	89%
Q9M2Z4	Arabidopsis thaliana	37%	70%
Q9UMX5	Homo sapiens	34%	95%
V5DM24	Trypanosoma cruzi	35%	91%