F-box domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QFB5_LEIMA

TriTrypDb:

LmjF.15.0700 , LMJLV39_150012800 , LMJSD75_150012900

Length:

1031

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 5
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QFB5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFB5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	354	358	PF00656	0.576
CLV_C14_Caspase3-7	36	40	PF00656	0.652
CLV_C14_Caspase3-7	479	483	PF00656	0.457
CLV_NRD_NRD_1	179	181	PF00675	0.708
CLV_NRD_NRD_1	287	289	PF00675	0.637
CLV_NRD_NRD_1	291	293	PF00675	0.639
CLV_NRD_NRD_1	308	310	PF00675	0.736
CLV_NRD_NRD_1	42	44	PF00675	0.446
CLV_NRD_NRD_1	431	433	PF00675	0.742
CLV_NRD_NRD_1	448	450	PF00675	0.769

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2X2	Leptomonas seymouri	46%	95%
A0A3Q8IA27	Leishmania donovani	90%	99%
A4H840	Leishmania braziliensis	67%	100%
A4HWG7	Leishmania infantum	89%	100%
E9AQ68	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	99%

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