Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QFB0_LEIMA

TriTrypDb:

LmjF.15.0750 , LMJLV39_150013500 , LMJSD75_150013700

Length:

677

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QFB0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QFB0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	178	182	PF00656	0.632
CLV_C14_Caspase3-7	436	440	PF00656	0.640
CLV_C14_Caspase3-7	508	512	PF00656	0.616
CLV_C14_Caspase3-7	612	616	PF00656	0.780
CLV_C14_Caspase3-7	622	626	PF00656	0.639
CLV_C14_Caspase3-7	670	674	PF00656	0.611
CLV_NRD_NRD_1	172	174	PF00675	0.817
CLV_NRD_NRD_1	420	422	PF00675	0.804
CLV_NRD_NRD_1	469	471	PF00675	0.587
CLV_NRD_NRD_1	591	593	PF00675	0.646
CLV_PCSK_KEX2_1	172	174	PF00082	0.817
CLV_PCSK_KEX2_1	420	422	PF00082	0.804
CLV_PCSK_KEX2_1	469	471	PF00082	0.575
CLV_PCSK_KEX2_1	590	592	PF00082	0.683
CLV_PCSK_PC7_1	416	422	PF00082	0.799
CLV_PCSK_SKI1_1	477	481	PF00082	0.527
DEG_SCF_FBW7_1	227	232	PF00400	0.762
DEG_SPOP_SBC_1	163	167	PF00917	0.769
DEG_SPOP_SBC_1	202	206	PF00917	0.649
DOC_CKS1_1	307	312	PF01111	0.790
DOC_PP2B_LxvP_1	340	343	PF13499	0.644
DOC_PP2B_LxvP_1	547	550	PF13499	0.713
DOC_PP2B_LxvP_1	649	652	PF13499	0.736
DOC_SPAK_OSR1_1	336	340	PF12202	0.654
DOC_USP7_MATH_1	110	114	PF00917	0.719
DOC_USP7_MATH_1	148	152	PF00917	0.722
DOC_USP7_MATH_1	163	167	PF00917	0.597
DOC_USP7_MATH_1	40	44	PF00917	0.709
DOC_USP7_MATH_1	411	415	PF00917	0.781
DOC_USP7_MATH_1	419	423	PF00917	0.670
DOC_USP7_MATH_1	526	530	PF00917	0.707
DOC_USP7_MATH_1	550	554	PF00917	0.712
DOC_USP7_MATH_1	626	630	PF00917	0.723
DOC_USP7_MATH_1	667	671	PF00917	0.705
DOC_USP7_MATH_1	92	96	PF00917	0.616
DOC_WW_Pin1_4	106	111	PF00397	0.659
DOC_WW_Pin1_4	165	170	PF00397	0.768
DOC_WW_Pin1_4	186	191	PF00397	0.792
DOC_WW_Pin1_4	209	214	PF00397	0.793
DOC_WW_Pin1_4	225	230	PF00397	0.587
DOC_WW_Pin1_4	247	252	PF00397	0.795
DOC_WW_Pin1_4	261	266	PF00397	0.649
DOC_WW_Pin1_4	282	287	PF00397	0.600
DOC_WW_Pin1_4	300	305	PF00397	0.677
DOC_WW_Pin1_4	306	311	PF00397	0.725
DOC_WW_Pin1_4	50	55	PF00397	0.801
DOC_WW_Pin1_4	522	527	PF00397	0.675
DOC_WW_Pin1_4	553	558	PF00397	0.624
LIG_14-3-3_CanoR_1	360	368	PF00244	0.733
LIG_14-3-3_CanoR_1	410	419	PF00244	0.837
LIG_14-3-3_CanoR_1	420	429	PF00244	0.632
LIG_14-3-3_CanoR_1	644	650	PF00244	0.720
LIG_AP2alpha_2	564	566	PF02296	0.548
LIG_BIR_III_2	245	249	PF00653	0.618
LIG_CtBP_PxDLS_1	286	290	PF00389	0.604
LIG_deltaCOP1_diTrp_1	481	490	PF00928	0.576
LIG_EVH1_1	340	344	PF00568	0.642
LIG_EVH1_2	342	346	PF00568	0.631
LIG_FHA_1	222	228	PF00498	0.744
LIG_FHA_1	566	572	PF00498	0.456
LIG_FHA_1	576	582	PF00498	0.507
LIG_FHA_1	644	650	PF00498	0.761
LIG_FHA_1	670	676	PF00498	0.623
LIG_FHA_2	283	289	PF00498	0.599
LIG_FHA_2	365	371	PF00498	0.754
LIG_FHA_2	463	469	PF00498	0.481
LIG_FHA_2	559	565	PF00498	0.576
LIG_FHA_2	605	611	PF00498	0.763
LIG_LIR_Gen_1	347	357	PF02991	0.659
LIG_LIR_Gen_1	481	491	PF02991	0.545
LIG_LIR_Nem_3	345	349	PF02991	0.635
LIG_LIR_Nem_3	481	486	PF02991	0.543
LIG_PDZ_Class_2	672	677	PF00595	0.755
LIG_Pex14_2	349	353	PF04695	0.629
LIG_SH2_CRK	476	480	PF00017	0.470
LIG_SH2_CRK	486	490	PF00017	0.573
LIG_SH3_1	338	344	PF00018	0.629
LIG_SH3_3	12	18	PF00018	0.767
LIG_SH3_3	210	216	PF00018	0.665
LIG_SH3_3	245	251	PF00018	0.771
LIG_SH3_3	296	302	PF00018	0.778
LIG_SH3_3	304	310	PF00018	0.723
LIG_SH3_3	336	342	PF00018	0.696
LIG_SH3_3	53	59	PF00018	0.683
LIG_SH3_3	98	104	PF00018	0.767
LIG_SH3_4	493	500	PF00018	0.426
LIG_TRAF2_1	43	46	PF00917	0.812
LIG_TRAF2_1	639	642	PF00917	0.812
MOD_CDK_SPxxK_3	165	172	PF00069	0.732
MOD_CK1_1	109	115	PF00069	0.812
MOD_CK1_1	127	133	PF00069	0.603
MOD_CK1_1	175	181	PF00069	0.742
MOD_CK1_1	183	189	PF00069	0.737
MOD_CK1_1	206	212	PF00069	0.826
MOD_CK1_1	250	256	PF00069	0.786
MOD_CK1_1	300	306	PF00069	0.779
MOD_CK1_1	363	369	PF00069	0.803
MOD_CK1_1	373	379	PF00069	0.671
MOD_CK1_1	453	459	PF00069	0.716
MOD_CK1_1	462	468	PF00069	0.656
MOD_CK1_1	553	559	PF00069	0.583
MOD_CK1_1	616	622	PF00069	0.804
MOD_CK1_1	628	634	PF00069	0.662
MOD_CK1_1	666	672	PF00069	0.635
MOD_CK2_1	128	134	PF00069	0.842
MOD_CK2_1	364	370	PF00069	0.747
MOD_CK2_1	40	46	PF00069	0.685
MOD_CK2_1	409	415	PF00069	0.790
MOD_CK2_1	427	433	PF00069	0.594
MOD_CK2_1	462	468	PF00069	0.689
MOD_CK2_1	489	495	PF00069	0.557
MOD_CK2_1	616	622	PF00069	0.841
MOD_CK2_1	635	641	PF00069	0.505
MOD_GlcNHglycan	149	153	PF01048	0.715
MOD_GlcNHglycan	181	185	PF01048	0.839
MOD_GlcNHglycan	205	208	PF01048	0.716
MOD_GlcNHglycan	258	261	PF01048	0.829
MOD_GlcNHglycan	362	365	PF01048	0.721
MOD_GlcNHglycan	392	395	PF01048	0.718
MOD_GlcNHglycan	421	424	PF01048	0.775
MOD_GlcNHglycan	429	432	PF01048	0.706
MOD_GlcNHglycan	458	461	PF01048	0.686
MOD_GlcNHglycan	528	531	PF01048	0.683
MOD_GlcNHglycan	552	555	PF01048	0.586
MOD_GlcNHglycan	618	621	PF01048	0.796
MOD_GlcNHglycan	638	641	PF01048	0.669
MOD_GlcNHglycan	665	668	PF01048	0.651
MOD_GlcNHglycan	94	97	PF01048	0.755
MOD_GSK3_1	106	113	PF00069	0.850
MOD_GSK3_1	124	131	PF00069	0.527
MOD_GSK3_1	148	155	PF00069	0.732
MOD_GSK3_1	159	166	PF00069	0.663
MOD_GSK3_1	172	179	PF00069	0.685
MOD_GSK3_1	180	187	PF00069	0.719
MOD_GSK3_1	202	209	PF00069	0.824
MOD_GSK3_1	221	228	PF00069	0.521
MOD_GSK3_1	246	253	PF00069	0.664
MOD_GSK3_1	293	300	PF00069	0.783
MOD_GSK3_1	309	316	PF00069	0.546
MOD_GSK3_1	355	362	PF00069	0.657
MOD_GSK3_1	369	376	PF00069	0.645
MOD_GSK3_1	522	529	PF00069	0.629
MOD_GSK3_1	57	64	PF00069	0.646
MOD_GSK3_1	592	599	PF00069	0.582
MOD_GSK3_1	616	623	PF00069	0.833
MOD_GSK3_1	631	638	PF00069	0.597
MOD_GSK3_1	663	670	PF00069	0.610
MOD_N-GLC_1	138	143	PF02516	0.607
MOD_N-GLC_1	355	360	PF02516	0.635
MOD_N-GLC_1	450	455	PF02516	0.553
MOD_N-GLC_1	620	625	PF02516	0.712
MOD_N-GLC_1	660	665	PF02516	0.503
MOD_NEK2_1	159	164	PF00069	0.789
MOD_NEK2_1	201	206	PF00069	0.799
MOD_NEK2_1	221	226	PF00069	0.526
MOD_NEK2_1	292	297	PF00069	0.749
MOD_NEK2_1	352	357	PF00069	0.515
MOD_NEK2_1	409	414	PF00069	0.847
MOD_NEK2_1	645	650	PF00069	0.745
MOD_NEK2_1	660	665	PF00069	0.473
MOD_PIKK_1	138	144	PF00454	0.609
MOD_PIKK_1	375	381	PF00454	0.784
MOD_PIKK_1	41	47	PF00454	0.812
MOD_PK_1	172	178	PF00069	0.819
MOD_PKA_1	172	178	PF00069	0.819
MOD_PKA_2	172	178	PF00069	0.819
MOD_PKA_2	359	365	PF00069	0.638
MOD_PKA_2	409	415	PF00069	0.808
MOD_PKA_2	419	425	PF00069	0.678
MOD_PKA_2	456	462	PF00069	0.742
MOD_PKA_2	643	649	PF00069	0.723
MOD_PKB_1	590	598	PF00069	0.556
MOD_Plk_1	138	144	PF00069	0.609
MOD_Plk_1	453	459	PF00069	0.728
MOD_Plk_1	660	666	PF00069	0.732
MOD_Plk_4	172	178	PF00069	0.860
MOD_Plk_4	206	212	PF00069	0.719
MOD_Plk_4	575	581	PF00069	0.513
MOD_Plk_4	61	67	PF00069	0.736
MOD_Plk_4	94	100	PF00069	0.759
MOD_ProDKin_1	106	112	PF00069	0.660
MOD_ProDKin_1	165	171	PF00069	0.770
MOD_ProDKin_1	186	192	PF00069	0.786
MOD_ProDKin_1	209	215	PF00069	0.792
MOD_ProDKin_1	225	231	PF00069	0.588
MOD_ProDKin_1	247	253	PF00069	0.795
MOD_ProDKin_1	261	267	PF00069	0.648
MOD_ProDKin_1	282	288	PF00069	0.602
MOD_ProDKin_1	300	306	PF00069	0.679
MOD_ProDKin_1	50	56	PF00069	0.797
MOD_ProDKin_1	522	528	PF00069	0.682
MOD_ProDKin_1	553	559	PF00069	0.624
TRG_DiLeu_BaLyEn_6	76	81	PF01217	0.711
TRG_ENDOCYTIC_2	476	479	PF00928	0.489
TRG_ENDOCYTIC_2	486	489	PF00928	0.569
TRG_ER_diArg_1	172	174	PF00400	0.817
TRG_ER_diArg_1	419	421	PF00400	0.799
TRG_ER_diArg_1	590	592	PF00400	0.724
TRG_ER_diArg_1	593	596	PF00400	0.755
TRG_Pf-PMV_PEXEL_1	477	481	PF00026	0.527

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WTM2	Leishmania donovani	87%	100%
A4H850	Leishmania braziliensis	59%	100%
A4HWH2	Leishmania infantum	87%	100%
E9AQ73	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	100%