LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QF98_LEIMA
TriTrypDb:
LmjF.15.0860 , LMJLV39_150015400 * , LMJSD75_150015500
Length:
325

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QF98
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QF98

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 294 298 PF00656 0.645
CLV_NRD_NRD_1 234 236 PF00675 0.561
CLV_NRD_NRD_1 321 323 PF00675 0.608
CLV_NRD_NRD_1 40 42 PF00675 0.522
CLV_PCSK_FUR_1 231 235 PF00082 0.557
CLV_PCSK_KEX2_1 233 235 PF00082 0.573
CLV_PCSK_KEX2_1 40 42 PF00082 0.522
CLV_PCSK_PC1ET2_1 233 235 PF00082 0.573
CLV_PCSK_SKI1_1 54 58 PF00082 0.573
DEG_SCF_FBW7_1 17 22 PF00400 0.486
DEG_SPOP_SBC_1 175 179 PF00917 0.606
DEG_SPOP_SBC_1 223 227 PF00917 0.645
DEG_SPOP_SBC_1 60 64 PF00917 0.622
DOC_ANK_TNKS_1 66 73 PF00023 0.643
DOC_CYCLIN_yCln2_LP_2 102 108 PF00134 0.506
DOC_MAPK_HePTP_8 26 38 PF00069 0.356
DOC_MAPK_MEF2A_6 29 38 PF00069 0.506
DOC_PP2B_LxvP_1 102 105 PF13499 0.493
DOC_USP7_MATH_1 19 23 PF00917 0.448
DOC_USP7_MATH_1 194 198 PF00917 0.602
DOC_USP7_MATH_1 211 215 PF00917 0.618
DOC_USP7_MATH_1 222 226 PF00917 0.692
DOC_USP7_MATH_1 259 263 PF00917 0.625
DOC_USP7_MATH_1 273 277 PF00917 0.676
DOC_USP7_MATH_1 60 64 PF00917 0.670
DOC_USP7_MATH_1 65 69 PF00917 0.676
DOC_USP7_UBL2_3 200 204 PF12436 0.632
DOC_USP7_UBL2_3 252 256 PF12436 0.629
DOC_WW_Pin1_4 15 20 PF00397 0.527
DOC_WW_Pin1_4 206 211 PF00397 0.801
DOC_WW_Pin1_4 274 279 PF00397 0.718
DOC_WW_Pin1_4 5 10 PF00397 0.677
DOC_WW_Pin1_4 87 92 PF00397 0.518
LIG_14-3-3_CanoR_1 112 119 PF00244 0.635
LIG_14-3-3_CanoR_1 29 38 PF00244 0.506
LIG_BIR_II_1 1 5 PF00653 0.664
LIG_BIR_III_1 1 5 PF00653 0.639
LIG_BIR_III_3 1 5 PF00653 0.639
LIG_BRCT_BRCA1_1 213 217 PF00533 0.546
LIG_FHA_1 167 173 PF00498 0.578
LIG_FHA_1 30 36 PF00498 0.502
LIG_FHA_2 149 155 PF00498 0.574
LIG_FHA_2 259 265 PF00498 0.651
LIG_LIR_Gen_1 214 224 PF02991 0.616
LIG_LIR_Gen_1 24 35 PF02991 0.502
LIG_LIR_Gen_1 301 312 PF02991 0.558
LIG_LIR_Nem_3 214 220 PF02991 0.617
LIG_LIR_Nem_3 24 30 PF02991 0.599
LIG_NRP_CendR_1 322 325 PF00754 0.630
LIG_PCNA_yPIPBox_3 20 29 PF02747 0.389
LIG_PTAP_UEV_1 3 8 PF05743 0.603
LIG_SH2_PTP2 27 30 PF00017 0.492
LIG_SH2_STAT5 27 30 PF00017 0.492
LIG_SH3_3 1 7 PF00018 0.774
LIG_SH3_3 241 247 PF00018 0.695
LIG_SH3_3 267 273 PF00018 0.701
LIG_SH3_3 275 281 PF00018 0.653
LIG_SH3_3 74 80 PF00018 0.758
LIG_SUMO_SIM_anti_2 316 322 PF11976 0.532
LIG_TRAF2_1 151 154 PF00917 0.553
LIG_TRAF2_1 22 25 PF00917 0.506
LIG_TRAF2_1 262 265 PF00917 0.722
LIG_TRAF2_1 283 286 PF00917 0.574
LIG_WW_2 280 283 PF00397 0.660
LIG_WW_3 247 251 PF00397 0.641
MOD_CK1_1 107 113 PF00069 0.689
MOD_CK1_1 127 133 PF00069 0.513
MOD_CK1_1 134 140 PF00069 0.630
MOD_CK1_1 199 205 PF00069 0.694
MOD_CK1_1 215 221 PF00069 0.545
MOD_CK1_1 226 232 PF00069 0.637
MOD_CK1_1 274 280 PF00069 0.670
MOD_CK2_1 134 140 PF00069 0.685
MOD_CK2_1 148 154 PF00069 0.558
MOD_CK2_1 155 161 PF00069 0.660
MOD_CK2_1 19 25 PF00069 0.629
MOD_CK2_1 258 264 PF00069 0.805
MOD_CK2_1 87 93 PF00069 0.540
MOD_GlcNHglycan 106 109 PF01048 0.666
MOD_GlcNHglycan 121 125 PF01048 0.552
MOD_GlcNHglycan 126 129 PF01048 0.590
MOD_GlcNHglycan 133 136 PF01048 0.578
MOD_GlcNHglycan 178 181 PF01048 0.633
MOD_GlcNHglycan 214 217 PF01048 0.657
MOD_GlcNHglycan 226 229 PF01048 0.575
MOD_GlcNHglycan 273 276 PF01048 0.731
MOD_GlcNHglycan 81 84 PF01048 0.594
MOD_GSK3_1 104 111 PF00069 0.674
MOD_GSK3_1 120 127 PF00069 0.553
MOD_GSK3_1 129 136 PF00069 0.621
MOD_GSK3_1 15 22 PF00069 0.530
MOD_GSK3_1 166 173 PF00069 0.672
MOD_GSK3_1 211 218 PF00069 0.697
MOD_GSK3_1 222 229 PF00069 0.694
MOD_GSK3_1 61 68 PF00069 0.697
MOD_N-GLC_1 259 264 PF02516 0.722
MOD_NEK2_1 174 179 PF00069 0.562
MOD_PIKK_1 29 35 PF00454 0.502
MOD_PKA_1 234 240 PF00069 0.569
MOD_PKA_1 40 46 PF00069 0.433
MOD_PKA_2 111 117 PF00069 0.701
MOD_PKA_2 234 240 PF00069 0.666
MOD_PKA_2 40 46 PF00069 0.445
MOD_PKA_2 60 66 PF00069 0.601
MOD_Plk_1 170 176 PF00069 0.669
MOD_Plk_1 259 265 PF00069 0.723
MOD_Plk_2-3 148 154 PF00069 0.674
MOD_Plk_2-3 163 169 PF00069 0.546
MOD_Plk_4 170 176 PF00069 0.669
MOD_ProDKin_1 15 21 PF00069 0.513
MOD_ProDKin_1 206 212 PF00069 0.798
MOD_ProDKin_1 274 280 PF00069 0.714
MOD_ProDKin_1 5 11 PF00069 0.678
MOD_ProDKin_1 87 93 PF00069 0.516
TRG_DiLeu_BaLyEn_6 186 191 PF01217 0.621
TRG_ENDOCYTIC_2 27 30 PF00928 0.613
TRG_NLS_MonoExtN_4 231 237 PF00514 0.569
TRG_Pf-PMV_PEXEL_1 189 193 PF00026 0.610

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WTH2 Leishmania donovani 88% 100%
A4H858 Leishmania braziliensis 63% 100%
A4HWI4 Leishmania infantum 87% 100%
E9AQ85 Leishmania mexicana (strain MHOM/GT/2001/U1103) 74% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS