NAD-specific glutamate dehydrogenase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glutamate dehydrogenase

Species:

Leishmania major

UniProt:

Q4QF83_LEIMA

TriTrypDb:

LmjF.15.1010 , LMJLV39_150017100 , LMJSD75_150017100

Length:

1020

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005739	mitochondrion	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QF83

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QF83

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	12
GO:0006103	2-oxoglutarate metabolic process	7	12
GO:0006106	fumarate metabolic process	7	12
GO:0006520	amino acid metabolic process	3	12
GO:0006536	glutamate metabolic process	6	12
GO:0006538	glutamate catabolic process	5	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009056	catabolic process	2	12
GO:0009063	amino acid catabolic process	4	12
GO:0009064	glutamine family amino acid metabolic process	5	12
GO:0009065	glutamine family amino acid catabolic process	6	12
GO:0009987	cellular process	1	12
GO:0016054	organic acid catabolic process	4	12
GO:0019551	glutamate catabolic process to 2-oxoglutarate	6	12
GO:0019752	carboxylic acid metabolic process	5	12
GO:0043436	oxoacid metabolic process	4	12
GO:0043648	dicarboxylic acid metabolic process	6	12
GO:0043649	dicarboxylic acid catabolic process	6	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044248	cellular catabolic process	3	12
GO:0044281	small molecule metabolic process	2	12
GO:0044282	small molecule catabolic process	3	12
GO:0046395	carboxylic acid catabolic process	5	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:1901565	organonitrogen compound catabolic process	4	12
GO:1901575	organic substance catabolic process	3	12
GO:1901605	alpha-amino acid metabolic process	4	12
GO:1901606	alpha-amino acid catabolic process	5	12

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	12
GO:0004352	glutamate dehydrogenase (NAD+) activity	6	12
GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	5	12
GO:0016491	oxidoreductase activity	2	12
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3	12
GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	4	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	877	881	PF00656	0.500
CLV_NRD_NRD_1	141	143	PF00675	0.339
CLV_NRD_NRD_1	167	169	PF00675	0.365
CLV_NRD_NRD_1	219	221	PF00675	0.468
CLV_NRD_NRD_1	409	411	PF00675	0.242
CLV_NRD_NRD_1	512	514	PF00675	0.248
CLV_NRD_NRD_1	664	666	PF00675	0.328
CLV_NRD_NRD_1	927	929	PF00675	0.298
CLV_PCSK_FUR_1	513	517	PF00082	0.249
CLV_PCSK_KEX2_1	219	221	PF00082	0.425
CLV_PCSK_KEX2_1	409	411	PF00082	0.262
CLV_PCSK_KEX2_1	512	514	PF00082	0.234
CLV_PCSK_KEX2_1	515	517	PF00082	0.230
CLV_PCSK_KEX2_1	972	974	PF00082	0.318
CLV_PCSK_PC1ET2_1	515	517	PF00082	0.232
CLV_PCSK_PC1ET2_1	972	974	PF00082	0.318
CLV_PCSK_PC7_1	215	221	PF00082	0.458
CLV_PCSK_SKI1_1	1006	1010	PF00082	0.316
CLV_PCSK_SKI1_1	124	128	PF00082	0.525
CLV_PCSK_SKI1_1	204	208	PF00082	0.506
CLV_PCSK_SKI1_1	215	219	PF00082	0.334
CLV_PCSK_SKI1_1	288	292	PF00082	0.354
CLV_PCSK_SKI1_1	350	354	PF00082	0.394
CLV_PCSK_SKI1_1	454	458	PF00082	0.231
CLV_PCSK_SKI1_1	516	520	PF00082	0.256
CLV_PCSK_SKI1_1	58	62	PF00082	0.416
CLV_PCSK_SKI1_1	621	625	PF00082	0.280
CLV_PCSK_SKI1_1	778	782	PF00082	0.201
CLV_PCSK_SKI1_1	787	791	PF00082	0.215
CLV_PCSK_SKI1_1	830	834	PF00082	0.233
CLV_PCSK_SKI1_1	876	880	PF00082	0.244
CLV_PCSK_SKI1_1	887	891	PF00082	0.190
CLV_PCSK_SKI1_1	959	963	PF00082	0.351
CLV_Separin_Metazoa	680	684	PF03568	0.441
DEG_APCC_DBOX_1	218	226	PF00400	0.341
DEG_APCC_DBOX_1	297	305	PF00400	0.337
DEG_APCC_DBOX_1	705	713	PF00400	0.406
DEG_SCF_FBW7_1	338	345	PF00400	0.455
DEG_SPOP_SBC_1	23	27	PF00917	0.434
DEG_SPOP_SBC_1	851	855	PF00917	0.397
DOC_CKS1_1	339	344	PF01111	0.308
DOC_CKS1_1	35	40	PF01111	0.495
DOC_CYCLIN_yClb5_NLxxxL_5	365	373	PF00134	0.459
DOC_MAPK_DCC_7	959	969	PF00069	0.369
DOC_MAPK_gen_1	142	150	PF00069	0.451
DOC_MAPK_gen_1	451	459	PF00069	0.220
DOC_MAPK_gen_1	685	694	PF00069	0.435
DOC_MAPK_gen_1	959	969	PF00069	0.415
DOC_MAPK_MEF2A_6	962	971	PF00069	0.314
DOC_MAPK_RevD_3	55	69	PF00069	0.319
DOC_PP1_RVXF_1	465	472	PF00149	0.243
DOC_PP1_RVXF_1	899	905	PF00149	0.500
DOC_PP2B_LxvP_1	789	792	PF13499	0.426
DOC_PP4_FxxP_1	593	596	PF00568	0.284
DOC_USP7_MATH_1	1015	1019	PF00917	0.467
DOC_USP7_MATH_1	23	27	PF00917	0.555
DOC_USP7_MATH_1	36	40	PF00917	0.483
DOC_USP7_UBL2_3	886	890	PF12436	0.441
DOC_WW_Pin1_4	191	196	PF00397	0.497
DOC_WW_Pin1_4	338	343	PF00397	0.294
DOC_WW_Pin1_4	34	39	PF00397	0.667
DOC_WW_Pin1_4	403	408	PF00397	0.364
DOC_WW_Pin1_4	45	50	PF00397	0.521
DOC_WW_Pin1_4	725	730	PF00397	0.417
LIG_14-3-3_CanoR_1	146	151	PF00244	0.400
LIG_14-3-3_CanoR_1	204	213	PF00244	0.500
LIG_14-3-3_CanoR_1	219	229	PF00244	0.343
LIG_14-3-3_CanoR_1	288	295	PF00244	0.364
LIG_14-3-3_CanoR_1	298	302	PF00244	0.299
LIG_14-3-3_CanoR_1	3	10	PF00244	0.556
LIG_14-3-3_CanoR_1	370	378	PF00244	0.397
LIG_14-3-3_CanoR_1	40	49	PF00244	0.567
LIG_14-3-3_CanoR_1	513	519	PF00244	0.249
LIG_14-3-3_CanoR_1	615	621	PF00244	0.313
LIG_14-3-3_CanoR_1	647	657	PF00244	0.412
LIG_14-3-3_CanoR_1	776	781	PF00244	0.406
LIG_14-3-3_CanoR_1	89	97	PF00244	0.513
LIG_14-3-3_CanoR_1	934	938	PF00244	0.421
LIG_Actin_WH2_2	957	974	PF00022	0.294
LIG_APCC_ABBA_1	177	182	PF00400	0.308
LIG_APCC_ABBA_1	257	262	PF00400	0.425
LIG_APCC_ABBA_1	387	392	PF00400	0.265
LIG_APCC_ABBAyCdc20_2	515	521	PF00400	0.220
LIG_BRCT_BRCA1_1	222	226	PF00533	0.471
LIG_BRCT_BRCA1_1	272	276	PF00533	0.278
LIG_BRCT_BRCA1_1	939	943	PF00533	0.332
LIG_BRCT_BRCA1_1	998	1002	PF00533	0.378
LIG_EH1_1	240	248	PF00400	0.327
LIG_FHA_1	248	254	PF00498	0.520
LIG_FHA_1	25	31	PF00498	0.588
LIG_FHA_1	325	331	PF00498	0.395
LIG_FHA_1	372	378	PF00498	0.449
LIG_FHA_1	381	387	PF00498	0.297
LIG_FHA_1	416	422	PF00498	0.407
LIG_FHA_1	45	51	PF00498	0.602
LIG_FHA_1	526	532	PF00498	0.229
LIG_FHA_1	542	548	PF00498	0.193
LIG_FHA_1	60	66	PF00498	0.436
LIG_FHA_1	641	647	PF00498	0.397
LIG_FHA_2	243	249	PF00498	0.393
LIG_FHA_2	343	349	PF00498	0.373
LIG_FHA_2	623	629	PF00498	0.311
LIG_FHA_2	745	751	PF00498	0.451
LIG_FHA_2	958	964	PF00498	0.310
LIG_GBD_Chelix_1	413	421	PF00786	0.364
LIG_LIR_Apic_2	337	342	PF02991	0.350
LIG_LIR_Apic_2	590	596	PF02991	0.282
LIG_LIR_Gen_1	114	121	PF02991	0.326
LIG_LIR_Gen_1	258	268	PF02991	0.313
LIG_LIR_Gen_1	392	401	PF02991	0.314
LIG_LIR_Gen_1	432	440	PF02991	0.250
LIG_LIR_Gen_1	651	659	PF02991	0.553
LIG_LIR_Gen_1	730	738	PF02991	0.434
LIG_LIR_Gen_1	758	767	PF02991	0.549
LIG_LIR_Gen_1	801	812	PF02991	0.414
LIG_LIR_Gen_1	903	910	PF02991	0.406
LIG_LIR_Gen_1	999	1008	PF02991	0.345
LIG_LIR_Nem_3	114	119	PF02991	0.322
LIG_LIR_Nem_3	167	173	PF02991	0.383
LIG_LIR_Nem_3	223	229	PF02991	0.395
LIG_LIR_Nem_3	258	263	PF02991	0.303
LIG_LIR_Nem_3	346	352	PF02991	0.366
LIG_LIR_Nem_3	392	396	PF02991	0.248
LIG_LIR_Nem_3	432	437	PF02991	0.233
LIG_LIR_Nem_3	468	474	PF02991	0.307
LIG_LIR_Nem_3	619	623	PF02991	0.311
LIG_LIR_Nem_3	651	657	PF02991	0.525
LIG_LIR_Nem_3	730	735	PF02991	0.434
LIG_LIR_Nem_3	758	764	PF02991	0.495
LIG_LIR_Nem_3	801	807	PF02991	0.458
LIG_LIR_Nem_3	857	862	PF02991	0.406
LIG_LIR_Nem_3	883	888	PF02991	0.417
LIG_LIR_Nem_3	903	907	PF02991	0.341
LIG_LIR_Nem_3	999	1005	PF02991	0.356
LIG_LYPXL_S_1	389	393	PF13949	0.364
LIG_PCNA_yPIPBox_3	945	959	PF02747	0.308
LIG_PCNA_yPIPBox_3	972	986	PF02747	0.295
LIG_Pex14_2	336	340	PF04695	0.261
LIG_Pex14_2	489	493	PF04695	0.220
LIG_Pex14_2	904	908	PF04695	0.397
LIG_PTB_Apo_2	304	311	PF02174	0.541
LIG_PTB_Apo_2	459	466	PF02174	0.249
LIG_Rb_LxCxE_1	318	337	PF01857	0.408
LIG_REV1ctd_RIR_1	1002	1010	PF16727	0.326
LIG_SH2_CRK	804	808	PF00017	0.476
LIG_SH2_GRB2like	1012	1015	PF00017	0.270
LIG_SH2_GRB2like	551	554	PF00017	0.248
LIG_SH2_GRB2like	804	807	PF00017	0.414
LIG_SH2_NCK_1	1012	1016	PF00017	0.326
LIG_SH2_NCK_1	764	768	PF00017	0.397
LIG_SH2_SRC	1012	1015	PF00017	0.245
LIG_SH2_SRC	567	570	PF00017	0.232
LIG_SH2_SRC	978	981	PF00017	0.274
LIG_SH2_STAP1	1012	1016	PF00017	0.326
LIG_SH2_STAP1	429	433	PF00017	0.364
LIG_SH2_STAT3	991	994	PF00017	0.287
LIG_SH2_STAT5	118	121	PF00017	0.355
LIG_SH2_STAT5	128	131	PF00017	0.265
LIG_SH2_STAT5	163	166	PF00017	0.311
LIG_SH2_STAT5	252	255	PF00017	0.294
LIG_SH2_STAT5	339	342	PF00017	0.298
LIG_SH2_STAT5	382	385	PF00017	0.244
LIG_SH2_STAT5	551	554	PF00017	0.232
LIG_SH2_STAT5	567	570	PF00017	0.232
LIG_SH2_STAT5	649	652	PF00017	0.500
LIG_SH2_STAT5	888	891	PF00017	0.406
LIG_SH2_STAT5	951	954	PF00017	0.278
LIG_SH2_STAT5	991	994	PF00017	0.319
LIG_SH3_2	195	200	PF14604	0.319
LIG_SH3_3	189	195	PF00018	0.579
LIG_SH3_3	303	309	PF00018	0.356
LIG_SH3_3	469	475	PF00018	0.220
LIG_SH3_3	571	577	PF00018	0.282
LIG_SH3_3	738	744	PF00018	0.406
LIG_SH3_3	766	772	PF00018	0.406
LIG_SH3_3	912	918	PF00018	0.326
LIG_SUMO_SIM_par_1	543	549	PF11976	0.220
LIG_SUMO_SIM_par_1	690	695	PF11976	0.426
LIG_TRAF2_1	185	188	PF00917	0.608
LIG_TRAF2_1	323	326	PF00917	0.413
LIG_TRAF2_1	865	868	PF00917	0.397
LIG_TRFH_1	459	463	PF08558	0.220
LIG_UBA3_1	571	580	PF00899	0.301
LIG_UBA3_1	892	901	PF00899	0.364
LIG_WRC_WIRS_1	434	439	PF05994	0.248
MOD_CDK_SPxK_1	34	40	PF00069	0.493
MOD_CDK_SPxK_1	403	409	PF00069	0.243
MOD_CDK_SPxxK_3	403	410	PF00069	0.364
MOD_CK1_1	255	261	PF00069	0.300
MOD_CK1_1	34	40	PF00069	0.609
MOD_CK1_1	343	349	PF00069	0.447
MOD_CK1_1	371	377	PF00069	0.426
MOD_CK1_1	44	50	PF00069	0.593
MOD_CK1_1	541	547	PF00069	0.220
MOD_CK1_1	619	625	PF00069	0.298
MOD_CK1_1	725	731	PF00069	0.232
MOD_CK1_1	874	880	PF00069	0.243
MOD_CK1_1	936	942	PF00069	0.373
MOD_CK2_1	180	186	PF00069	0.410
MOD_CK2_1	242	248	PF00069	0.401
MOD_CK2_1	320	326	PF00069	0.427
MOD_CK2_1	402	408	PF00069	0.244
MOD_CK2_1	649	655	PF00069	0.265
MOD_CK2_1	744	750	PF00069	0.334
MOD_CK2_1	77	83	PF00069	0.417
MOD_CK2_1	795	801	PF00069	0.219
MOD_CK2_1	851	857	PF00069	0.220
MOD_CK2_1	862	868	PF00069	0.220
MOD_CK2_1	89	95	PF00069	0.313
MOD_CK2_1	957	963	PF00069	0.328
MOD_CMANNOS	908	911	PF00535	0.243
MOD_GlcNHglycan	1017	1020	PF01048	0.399
MOD_GlcNHglycan	182	185	PF01048	0.675
MOD_GlcNHglycan	43	46	PF01048	0.621
MOD_GlcNHglycan	693	697	PF01048	0.220
MOD_GlcNHglycan	79	82	PF01048	0.513
MOD_GlcNHglycan	843	847	PF01048	0.232
MOD_GlcNHglycan	873	876	PF01048	0.270
MOD_GlcNHglycan	988	991	PF01048	0.287
MOD_GSK3_1	18	25	PF00069	0.619
MOD_GSK3_1	268	275	PF00069	0.280
MOD_GSK3_1	320	327	PF00069	0.374
MOD_GSK3_1	334	341	PF00069	0.226
MOD_GSK3_1	36	43	PF00069	0.433
MOD_GSK3_1	376	383	PF00069	0.324
MOD_GSK3_1	429	436	PF00069	0.231
MOD_GSK3_1	541	548	PF00069	0.279
MOD_GSK3_1	70	77	PF00069	0.375
MOD_GSK3_1	867	874	PF00069	0.377
MOD_GSK3_1	933	940	PF00069	0.345
MOD_GSK3_1	992	999	PF00069	0.312
MOD_LATS_1	869	875	PF00433	0.364
MOD_N-GLC_1	173	178	PF02516	0.506
MOD_N-GLC_1	659	664	PF02516	0.207
MOD_N-GLC_1	722	727	PF02516	0.427
MOD_N-GLC_1	89	94	PF02516	0.472
MOD_N-GLC_2	448	450	PF02516	0.243
MOD_NEK2_1	180	185	PF00069	0.615
MOD_NEK2_1	2	7	PF00069	0.520
MOD_NEK2_1	270	275	PF00069	0.257
MOD_NEK2_1	369	374	PF00069	0.381
MOD_NEK2_1	41	46	PF00069	0.608
MOD_NEK2_1	433	438	PF00069	0.243
MOD_NEK2_1	525	530	PF00069	0.220
MOD_NEK2_1	546	551	PF00069	0.300
MOD_NEK2_1	722	727	PF00069	0.235
MOD_NEK2_1	74	79	PF00069	0.355
MOD_NEK2_1	82	87	PF00069	0.331
MOD_NEK2_2	324	329	PF00069	0.356
MOD_NEK2_2	429	434	PF00069	0.231
MOD_NEK2_2	649	654	PF00069	0.364
MOD_PIKK_1	371	377	PF00454	0.417
MOD_PIKK_1	525	531	PF00454	0.220
MOD_PIKK_1	59	65	PF00454	0.351
MOD_PIKK_1	823	829	PF00454	0.220
MOD_PIKK_1	89	95	PF00454	0.483
MOD_PK_1	776	782	PF00069	0.220
MOD_PKA_2	2	8	PF00069	0.587
MOD_PKA_2	297	303	PF00069	0.333
MOD_PKA_2	369	375	PF00069	0.387
MOD_PKA_2	380	386	PF00069	0.232
MOD_PKA_2	39	45	PF00069	0.534
MOD_PKA_2	491	497	PF00069	0.220
MOD_PKA_2	933	939	PF00069	0.332
MOD_PKB_1	776	784	PF00069	0.215
MOD_Plk_1	173	179	PF00069	0.513
MOD_Plk_1	324	330	PF00069	0.251
MOD_Plk_1	429	435	PF00069	0.231
MOD_Plk_1	82	88	PF00069	0.414
MOD_Plk_2-3	182	188	PF00069	0.444
MOD_Plk_2-3	795	801	PF00069	0.213
MOD_Plk_4	221	227	PF00069	0.351
MOD_Plk_4	242	248	PF00069	0.374
MOD_Plk_4	25	31	PF00069	0.644
MOD_Plk_4	252	258	PF00069	0.263
MOD_Plk_4	297	303	PF00069	0.405
MOD_Plk_4	324	330	PF00069	0.255
MOD_Plk_4	382	388	PF00069	0.248
MOD_Plk_4	429	435	PF00069	0.237
MOD_Plk_4	541	547	PF00069	0.220
MOD_Plk_4	649	655	PF00069	0.364
MOD_Plk_4	74	80	PF00069	0.470
MOD_Plk_4	744	750	PF00069	0.248
MOD_Plk_4	795	801	PF00069	0.259
MOD_Plk_4	836	842	PF00069	0.364
MOD_Plk_4	917	923	PF00069	0.343
MOD_Plk_4	933	939	PF00069	0.287
MOD_ProDKin_1	191	197	PF00069	0.486
MOD_ProDKin_1	338	344	PF00069	0.303
MOD_ProDKin_1	34	40	PF00069	0.669
MOD_ProDKin_1	403	409	PF00069	0.364
MOD_ProDKin_1	45	51	PF00069	0.503
MOD_ProDKin_1	725	731	PF00069	0.248
MOD_SUMO_for_1	586	589	PF00179	0.489
MOD_SUMO_for_1	900	903	PF00179	0.356
MOD_SUMO_rev_2	165	171	PF00179	0.531
MOD_SUMO_rev_2	208	213	PF00179	0.611
MOD_SUMO_rev_2	695	704	PF00179	0.302
MOD_SUMO_rev_2	795	805	PF00179	0.395
TRG_DiLeu_BaEn_1	297	302	PF01217	0.525
TRG_DiLeu_BaEn_1	392	397	PF01217	0.377
TRG_DiLeu_BaEn_2	324	330	PF01217	0.395
TRG_DiLeu_BaEn_2	588	594	PF01217	0.438
TRG_DiLeu_BaEn_3	208	214	PF01217	0.344
TRG_DiLeu_BaEn_4	589	595	PF01217	0.429
TRG_DiLeu_BaEn_4	707	713	PF01217	0.229
TRG_DiLeu_BaEn_4	897	903	PF01217	0.364
TRG_ENDOCYTIC_2	349	352	PF00928	0.345
TRG_ENDOCYTIC_2	390	393	PF00928	0.235
TRG_ENDOCYTIC_2	398	401	PF00928	0.204
TRG_ENDOCYTIC_2	654	657	PF00928	0.310
TRG_ENDOCYTIC_2	804	807	PF00928	0.329
TRG_ER_diArg_1	218	220	PF00400	0.466
TRG_ER_diArg_1	511	513	PF00400	0.249
TRG_NLS_MonoExtN_4	134	140	PF00514	0.344
TRG_Pf-PMV_PEXEL_1	959	963	PF00026	0.351

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZF0	Leptomonas seymouri	77%	100%
A0A0S4JKD0	Bodo saltans	53%	100%
A0A1X0NVM8	Trypanosomatidae	62%	100%
A0A3R7KF21	Trypanosoma rangeli	61%	100%
A0A3S7WTK6	Leishmania donovani	97%	100%
A4H874	Leishmania braziliensis	90%	100%
A4HWJ9	Leishmania infantum	97%	100%
C9ZXU0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
E9AQA0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
P00365	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	38%	97%
P33327	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	93%
Q54VI3	Dictyostelium discoideum	43%	98%
Q9USN5	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	92%
V5B4M0	Trypanosoma cruzi	61%	100%