LeishMANIAdb
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Integrase_SAM-like_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Integrase_SAM-like_N domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QF37_LEIMA
TriTrypDb:
LmjF.15.1430 , LMJLV39_150021300 * , LMJSD75_150021300 *
Length:
95

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QF37
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QF37

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 77 81 PF00082 0.606
DEG_SCF_FBW7_1 1 8 PF00400 0.715
DOC_CYCLIN_yClb5_NLxxxL_5 66 73 PF00134 0.531
DOC_MAPK_RevD_3 73 87 PF00069 0.530
DOC_USP7_MATH_1 11 15 PF00917 0.558
DOC_USP7_MATH_1 5 9 PF00917 0.722
DOC_WW_Pin1_4 1 6 PF00397 0.691
DOC_WW_Pin1_4 32 37 PF00397 0.662
LIG_14-3-3_CanoR_1 24 34 PF00244 0.542
LIG_14-3-3_CanoR_1 52 60 PF00244 0.604
LIG_BIR_II_1 1 5 PF00653 0.588
LIG_FHA_1 17 23 PF00498 0.743
LIG_FHA_1 26 32 PF00498 0.679
LIG_FHA_2 2 8 PF00498 0.790
LIG_LIR_Nem_3 76 82 PF02991 0.566
LIG_SH2_STAT5 82 85 PF00017 0.512
MOD_CK2_1 11 17 PF00069 0.803
MOD_GlcNHglycan 14 17 PF01048 0.479
MOD_GlcNHglycan 7 10 PF01048 0.664
MOD_GSK3_1 1 8 PF00069 0.675
MOD_GSK3_1 12 19 PF00069 0.719
MOD_N-GLC_1 12 17 PF02516 0.656
MOD_PKA_2 51 57 PF00069 0.620
MOD_ProDKin_1 1 7 PF00069 0.692
MOD_ProDKin_1 32 38 PF00069 0.662

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I0X5 Leptomonas seymouri 33% 100%
A0A3Q8IA91 Leishmania donovani 86% 100%
A0A3R7K7I4 Trypanosoma rangeli 34% 88%
A4HWN0 Leishmania infantum 86% 100%
E9AI51 Leishmania braziliensis 59% 100%
E9AQD8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS